4HWZ
 
 | | Structure of HLA-A68 complexed with an HIV derived peptide | | 分子名称: | 9-mer peptide from Pol protein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | | 登録日 | 2012-11-09 | | 公開日 | 2013-10-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | | 主引用文献 | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
|
|
4I48
 | | Structure of HLA-A68 complexed with an HIV Env derived peptide | | 分子名称: | 9-mer peptide from Envelope glycoprotein gp160, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | | 登録日 | 2012-11-27 | | 公開日 | 2013-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.799 Å) | | 主引用文献 | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
|
|
7XYQ
 | | Crystal strucutre of PD-L1 and the computationally designed DBL1_03 protein binder | | 分子名称: | ARGININE, CD274 molecule, DBL1_03 | | 著者 | Liu, K, Xu, Z, Han, P, Pacesa, M, Gao, G.F, Chai, Y, Tan, S. | | 登録日 | 2022-06-02 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-05-17 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | De novo design of protein interactions with learned surface fingerprints.
Nature, 617, 2023
|
|
7WVM
 | | The complex structure of PD-1 and cemiplimab | | 分子名称: | Heavy Chain of Cemiplimab, Light Chain of Cemiplimab, Programmed cell death protein 1 | | 著者 | Lu, D, Xu, Z.P, Liu, K.F, Tan, S.G, Gao, G.F, Chai, Y. | | 登録日 | 2022-02-10 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | PD-1 N58-Glycosylation-Dependent Binding of Monoclonal Antibody Cemiplimab for Immune Checkpoint Therapy.
Front Immunol, 13, 2022
|
|
4HX1
 | | Structure of HLA-A68 complexed with a tumor antigen derived peptide | | 分子名称: | 9-mer peptide from Tyrosinase-related protein-2, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | | 登録日 | 2012-11-09 | | 公開日 | 2013-10-02 | | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | | 主引用文献 | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
|
|
7C8J
 | | Structural basis for cross-species recognition of COVID-19 virus spike receptor binding domain to bat ACE2 | | 分子名称: | Angiotensin-converting enzyme, SARS-CoV-2 Receptor binding domain, ZINC ION | | 著者 | Liu, K.F, Wang, J, Tan, S.G, Niu, S, Wu, L.L, Zhang, Y.F, Pan, X.Q, Meng, Y.M, Chen, Q, Wang, Q.H, Wang, H.W, Qi, J.X, Gao, G.F. | | 登録日 | 2020-06-01 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | | 主引用文献 | Cross-species recognition of SARS-CoV-2 to bat ACE2.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
3RL1
 | | HIV RT derived peptide complexed to HLA-A*0301 | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-3 alpha chain, ... | | 著者 | Zhang, S, Liu, J, Cheng, H, Tan, S, Qi, J, Yan, J, Gao, G.F. | | 登録日 | 2011-04-19 | | 公開日 | 2012-02-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Mol.Immunol., 49, 2011
|
|
4JZG
 | | Crystal structure of a single cambialistic SOD2 occupied by Manganese ion from Clostridium difficile | | 分子名称: | MANGANESE (II) ION, Superoxide dismutase | | 著者 | Li, W, Wang, C.L, Zhao, Y, Wang, H.F, Tan, S.X. | | 登録日 | 2013-04-02 | | 公開日 | 2014-04-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.321 Å) | | 主引用文献 | Crystal structure of a single cambialistic SOD2 occupied by Manganese ion from Clostridium difficile
To be Published
|
|
3RL2
 | | HIV Nef derived peptide Nef73 complexed to HLA-A*0301 | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-3 alpha chain, ... | | 著者 | Zhang, S, Liu, J, Cheng, H, Tan, S, Qi, J, Yan, J, Gao, G.F. | | 登録日 | 2011-04-19 | | 公開日 | 2012-02-29 | | 実験手法 | X-RAY DIFFRACTION (2.386 Å) | | 主引用文献 | Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Mol.Immunol., 49, 2011
|
|
7XAE
 | | Crystal strucutre of PD-L1 and 3ONJA protein | | 分子名称: | 2IC6, Programmed cell death 1 ligand 1 | | 著者 | Liu, K.F, Xu, Z.P, Han, P, Gao, G.F, Chai, Y, Tan, S.G. | | 登録日 | 2022-03-17 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.44 Å) | | 主引用文献 | Crystal strucutre of PD-L1 and 2IC6 protein
To Be Published
|
|
7XOE
 | | Cryo-EM structure of S glycoprotein encoded by the Covid-19 mRNA vaccine candidate RQ3013 (Prefusion state) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,peptide | | 著者 | Wu, Z, Yu, Z, Tan, S, Lu, J, Lu, G, Lin, J. | | 登録日 | 2022-05-01 | | 公開日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants.
Sci Bull (Beijing), 68, 2023
|
|
7XOG
 | | Cryo-EM structure of S glycoprotein encoded by the Covid-19 mRNA vaccine candidate RQ3013 (Postfusion state) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,peptide, ... | | 著者 | Wu, Z, Yu, Z, Tan, S, Lu, J, Lu, G, Lin, J. | | 登録日 | 2022-05-01 | | 公開日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants.
Sci Bull (Beijing), 68, 2023
|
|
6CW2
 | | Crystal structure of a yeast SAGA transcriptional coactivator Ada2/Gcn5 HAT subcomplex, crystal form 1 | | 分子名称: | Histone acetyltransferase GCN5, Transcriptional adapter 2, ZINC ION, ... | | 著者 | Sun, J, Paduch, M, Kim, S.A, Kramer, R.M, Barrios, A.F, Lu, V, Luke, J, Usatyuk, S, Kossiakoff, A.A, Tan, S. | | 登録日 | 2018-03-29 | | 公開日 | 2018-09-19 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6CW3
 | | Crystal structure of a yeast SAGA transcriptional coactivator Ada2/Gcn5 HAT subcomplex, crystal form 2 | | 分子名称: | Histone acetyltransferase GCN5, Transcriptional adapter 2, ZINC ION, ... | | 著者 | Sun, J, Paduch, M, Kim, S.A, Kramer, R.M, Barrios, A.F, Lu, V, Luke, J, Usatyuk, S, Kossiakoff, A.A, Tan, S. | | 登録日 | 2018-03-29 | | 公開日 | 2018-09-19 | | 最終更新日 | 2020-03-04 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
7C8K
 | | Structural basis for cross-species recognition of COVID-19 virus spike receptor binding domain to bat ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | | 著者 | Liu, K.F, Wang, J, Tan, S.G, Niu, S, Wu, L.L, Zhang, Y.F, Pan, X.Q, Meng, Y.M, Chen, Q, Wang, Q.H, Wang, H.W, Qi, J.X, Gao, G.F. | | 登録日 | 2020-06-02 | | 公開日 | 2021-01-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cross-species recognition of SARS-CoV-2 to bat ACE2.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
8Y46
 | | Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase bound to L-KDF or L-2,4-DKDF | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, L-2,4-diketo-3-deoxyfuconate, ... | | 著者 | Akagashi, M, Watanabe, S. | | 登録日 | 2024-01-30 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase reveals a unique binding mode as a alpha-furanosyl hemiketal of substrates.
Sci Rep, 14, 2024
|
|
7C3M
 | | Structure of FERM protein | | 分子名称: | Fermitin family homolog 3,Fermitin family homolog 3,Fermitin family homolog 3 | | 著者 | Bu, W, Loh, Z.Y, Jin, S, Basu, S, Ero, R, Park, J.E, Yan, X, Wang, M, Sze, S.K, Tan, S.M, Gao, Y.G. | | 登録日 | 2020-05-13 | | 公開日 | 2020-06-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural basis of human full-length kindlin-3 homotrimer in an auto-inhibited state.
Plos Biol., 18, 2020
|
|
7CU5
 | | N-Glycosylation of PD-1 and glycosylation dependent binding of PD-1 specific monoclonal antibody camrelizumab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Programmed cell death protein 1, ... | | 著者 | Liu, K.F, Tan, S.G, Jin, W.J, Guan, J.W, Wang, W.L, Sun, H, Qi, J.X, Yan, J.H, Chai, Y, Wang, Z.F, Chu, X.D, Gao, G.F. | | 登録日 | 2020-08-21 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | N-glycosylation of PD-1 promotes binding of camrelizumab.
Embo Rep., 21, 2020
|
|
8Y11
 | |
8Y4B
 | |
8Y4J
 | |
7C88
 | | Complex structure of JS003 and PD-L1 | | 分子名称: | JS003 Heavy chain, JS003 Light chain, Programmed cell death 1 ligand 1 | | 著者 | Bi, X, Shi, R, Chai, Y, Qi, J, Yan, J, Tan, S. | | 登録日 | 2020-05-29 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | | 主引用文献 | Identification of a hotspot on PD-L1 for pH-dependent binding by monoclonal antibodies for tumor therapy.
Signal Transduct Target Ther, 5, 2020
|
|
8XWK
 | |
2P28
 | | Structure of the PHE2 and PHE3 fragments of the integrin beta2 subunit | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-2 | | 著者 | Shi, M, Foo, S.Y, Tan, S.M, Mitchell, E.P, Law, S.K.A, Lescar, J. | | 登録日 | 2007-03-07 | | 公開日 | 2007-08-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A structural hypothesis for the transition between bent and extended conformations of the leukocyte beta2 integrins
J.Biol.Chem., 282, 2007
|
|
7CP2
 | | Crystal structure of the African swine fever virus core shell protein p15 | | 分子名称: | CP530R | | 著者 | Liu, K.F, Meng, Y.M, Chai, Y, Li, L.J, Sun, H, Gao, G.F, Tan, S.G, Qi, J.X. | | 登録日 | 2020-08-05 | | 公開日 | 2020-10-28 | | 最終更新日 | 2021-05-19 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Crystal structure of the African swine fever virus core shell protein p15
Biosaf Health, 2021
|
|
