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PDB: 367 results

5WC1
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BU of 5wc1 by Molmil
katanin AAA ATPase domain
Descriptor: Meiotic spindle formation protein mei-1, SULFATE ION
Authors:Szyk, A, Roll-Mecak, A.
Deposit date:2017-06-29
Release date:2017-08-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Katanin spiral and ring structures shed light on power stroke for microtubule severing.
Nat. Struct. Mol. Biol., 24, 2017
1R1G
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BU of 1r1g by Molmil
Crystal Structure of the Scorpion Toxin BmBKTtx1
Descriptor: Neurotoxin BmK37
Authors:Szyk, A, Lu, W, Xu, C, Lubkowski, J.
Deposit date:2003-09-23
Release date:2004-03-02
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structure of the scorpion toxin BmBKTtx1 solved from single wavelength anomalous scattering of sulfur.
J.Struct.Biol., 145, 2004
4PK3
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BU of 4pk3 by Molmil
tubulin acetyltransferase complex with bisubstrate analog
Descriptor: ACETYL-SER-ASP-(N-ACETYL-LYS)-THR-NH2 PEPTIDE, Alpha-tubulin N-acetyltransferase 1, COENZYME A
Authors:Szyk, A, Roll-Mecak, A.
Deposit date:2014-05-13
Release date:2014-08-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.347 Å)
Cite:Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase.
Cell, 157, 2014
4PK2
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tubulin acetyltransferase complex with bisubstrate analog
Descriptor: ACETYL-SER-(N-PROPANOYL-LYS)-ASP--THR-NH2 PEPTIDE, Alpha-tubulin N-acetyltransferase 1, COENZYME A
Authors:Szyk, A, Roll-Mecak, A.
Deposit date:2014-05-13
Release date:2014-08-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase.
Cell, 157, 2014
2FZS
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BU of 2fzs by Molmil
Crystal structure of E. coli ClpP with a Peptide Chloromethyl Ketone Covalently Bound at the Active Site
Descriptor: ATP-dependent Clp protease proteolytic subunit, GLYCEROL, N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE, ...
Authors:Szyk, A, Maurizi, M.R.
Deposit date:2006-02-10
Release date:2006-05-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure at 1.9A of E. coli ClpP with a peptide covalently bound at the active site.
J.Struct.Biol., 156, 2006
6YYE
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BU of 6yye by Molmil
TREM2 extracellular domain (19-131) in complex with single-chain variable fragment (scFv-2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, TREM2 Single chain variable 2, Triggering receptor expressed on myeloid cells 2
Authors:Szykowska, A, Preger, C, Krojer, T, Mukhopadhyay, S.M.M, McKinley, G, Graslund, S, Wigren, E, Persson, H, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Di Daniel, E, Burgess-Brown, N, Bullock, A.
Deposit date:2020-05-04
Release date:2021-02-17
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.36 Å)
Cite:Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.
Structure, 29, 2021
6YMQ
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BU of 6ymq by Molmil
TREM2 extracellular domain (19-131) in complex with single-chain variable 4 (scFv-4)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Single-chain variable 4, ...
Authors:Szykowska, A, Preger, C, Scacioc, A, Mukhopadhyay, S.M.M, McKinley, G, Graslund, S, Wigren, E, Persson, H, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Di Daniel, E, Davis, J.B, Burgess-Brown, N, Bullock, A.
Deposit date:2020-04-09
Release date:2021-02-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.
Structure, 29, 2021
6Y6C
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BU of 6y6c by Molmil
TREM2 extracellular domain (19-174) in complex with single-chain variable fragment (scFv-4)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Single chain variable, Triggering receptor expressed on myeloid cells 2
Authors:Szykowska, A, Preger, C, Williams, E, Mukhopadhyay, S.M.M, McKinley, G, Gruslund, S, Wigren, E, Persson, H, Arrowsmith, C.H, Edwards, A, von Delft, F, Bountra, C, Davis, J.B, Di Daniel, E, Burgess-Brown, N, Bullock, A.
Deposit date:2020-02-26
Release date:2021-02-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.
Structure, 29, 2021
5JCO
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BU of 5jco by Molmil
Structure and dynamics of single-isoform recombinant neuronal human tubulin
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Vemu, A, Atherton, J, Spector, J.O, Szyk, A, Moores, C.A, Roll-Mecak, A.
Deposit date:2016-04-15
Release date:2016-05-04
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure and Dynamics of Single-isoform Recombinant Neuronal Human Tubulin.
J.Biol.Chem., 291, 2016
5WC0
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BU of 5wc0 by Molmil
katanin hexamer in spiral conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Meiotic spindle formation protein mei-1
Authors:Zehr, E.A, Szyk, A, Piszczek, G, Szczesna, E, Zuo, X, Roll-Mecak, A.
Deposit date:2017-06-29
Release date:2017-08-09
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Katanin spiral and ring structures shed light on power stroke for microtubule severing.
Nat. Struct. Mol. Biol., 24, 2017
5WCB
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BU of 5wcb by Molmil
Katanin hexamer in the ring conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Meiotic spindle formation protein mei-1
Authors:Zehr, E.A, Szyk, A, Piszczek, G, Szczesna, E, Zuo, X, Roll-Mecak, A.
Deposit date:2017-06-29
Release date:2017-08-09
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Katanin spiral and ring structures shed light on power stroke for microtubule severing.
Nat. Struct. Mol. Biol., 24, 2017
6P07
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BU of 6p07 by Molmil
Spastin hexamer in complex with substrate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Sandate, C.R, Szyk, A, Zehr, E, Roll-Mecak, A, Lander, G.C.
Deposit date:2019-05-16
Release date:2019-06-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:An allosteric network in spastin couples multiple activities required for microtubule severing.
Nat.Struct.Mol.Biol., 26, 2019
1ZMM
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BU of 1zmm by Molmil
Crystal structure of human alpha-defensin-4
Descriptor: Neutrophil defensin 4
Authors:Lubkowski, J, Szyk, A, Lu, W.
Deposit date:2005-05-10
Release date:2006-05-30
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6.
Protein Sci., 15, 2006
1ZMQ
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BU of 1zmq by Molmil
Crystal structure of human alpha-defensin-6
Descriptor: CHLORIDE ION, Defensin 6
Authors:Lubkowski, J, Szyk, A, Lu, W.
Deposit date:2005-05-10
Release date:2006-05-30
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6.
Protein Sci., 15, 2006
4YLR
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BU of 4ylr by Molmil
Tubulin Glutamylase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Tubulin polyglutamylase TTLL7
Authors:Garnham, C.P, Vemu, A, Wilson-Kubalek, E.M, Yu, I, Szyk, A, Lander, G.C, Milligan, R.A, Roll-Mecak, A.
Deposit date:2015-03-05
Release date:2015-06-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.
Cell, 161, 2015
4YLS
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BU of 4yls by Molmil
Tubulin Glutamylase
Descriptor: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Tubulin polyglutamylase TTLL7
Authors:Garnham, C.P, Vemu, A, Wilson-Kubalek, E.M, Yu, I, Szyk, A, Lander, G.C, Milligan, R.A, Roll-Mecak, A.
Deposit date:2015-03-05
Release date:2015-06-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.
Cell, 161, 2015
1ZMP
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BU of 1zmp by Molmil
Crystal structure of human defensin-5
Descriptor: CHLORIDE ION, Defensin 5, GLYCEROL, ...
Authors:Lubkowski, J, Szyk, A, Lu, W.
Deposit date:2005-05-10
Release date:2006-05-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6.
Protein Sci., 15, 2006
4H6U
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BU of 4h6u by Molmil
Tubulin acetyltransferase mutant
Descriptor: ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, PHOSPHATE ION, ...
Authors:Roll-Mecak, A, Kizub, V, Szyk, A.
Deposit date:2012-09-19
Release date:2012-11-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4482 Å)
Cite:Crystal structures of tubulin acetyltransferase reveal a conserved catalytic core and the plasticity of the essential N terminus.
J.Biol.Chem., 287, 2012
4H6Z
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BU of 4h6z by Molmil
Tubulin acetyltransferase
Descriptor: ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, PHOSPHATE ION
Authors:Kizub, L, Szyk, A, Piszczek, G, Roll-Mecak, A.
Deposit date:2012-09-19
Release date:2012-11-07
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Crystal structures of tubulin acetyltransferase reveal a conserved catalytic core and the plasticity of the essential N terminus.
J.Biol.Chem., 287, 2012
3TII
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BU of 3tii by Molmil
Tubulin tyrosine ligase
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ttl protein
Authors:Roll-Mecak, A, Szyk, A, Deaconescu, A, Piszczek, G.
Deposit date:2011-08-20
Release date:2011-10-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin.
Nat.Struct.Mol.Biol., 18, 2011
3TIG
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BU of 3tig by Molmil
Tubulin tyrosine ligase
Descriptor: MAGNESIUM ION, Ttl protein
Authors:Roll-Mecak, A, Szyk, A, Deaconescu, A, Piszczek, G.
Deposit date:2011-08-20
Release date:2011-10-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin.
Nat.Struct.Mol.Biol., 18, 2011
3TIN
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BU of 3tin by Molmil
Tubulin tyrosine ligase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ttl protein
Authors:Roll-Mecak, A, Szyk, A, Deaconescu, A, Piszczek, G.
Deposit date:2011-08-20
Release date:2011-10-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin.
Nat.Struct.Mol.Biol., 18, 2011
3OII
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BU of 3oii by Molmil
Crystal structure of Saccharomyces Cerevisiae Nep1/Emg1 bound to S-adenosylhomocysteine
Descriptor: Essential for mitotic growth 1, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Thomas, S.R, Szyk, A, LaRonde-LeBlanc, N.
Deposit date:2010-08-19
Release date:2010-12-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
Nucleic Acids Res., 39, 2011
8V4K
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BU of 8v4k by Molmil
CCP5 in complex with microtubules class1
Descriptor: Cytosolic carboxypeptidase-like protein 5, GLUTAMIC ACID, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Chen, J, Zehr, E.A, Gruschus, J.M, Szyk, A, Liu, Y, Tanner, M.E, Tjandra, N, Roll-Mecak, A.
Deposit date:2023-11-29
Release date:2024-07-17
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Tubulin code eraser CCP5 binds branch glutamates by substrate deformation.
Nature, 631, 2024
8V3O
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BU of 8v3o by Molmil
CCP5 in complex with Glu-P-peptide 1 transition state analog
Descriptor: Cytosolic carboxypeptidase-like protein 5, D-MALATE, POTASSIUM ION, ...
Authors:Chen, J, Zehr, E.A, Gruschus, J.M, Szyk, A, Liu, Y, Tanner, M.E, Tjandra, N, Roll-Mecak, A.
Deposit date:2023-11-28
Release date:2024-07-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Tubulin code eraser CCP5 binds branch glutamates by substrate deformation.
Nature, 631, 2024

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