2G3Y
 
 | | Crystal structure of the human small GTPase GEM | | Descriptor: | GTP-binding protein GEM, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Ugochukwu, E, Soundararajan, M, Elkins, J, Gileadi, C, Schoch, G, Sobott, F, Fedorov, O, Bray, J, Pantic, N, Berridge, G, Burgess, N, Lee, W.H, Turnbull, A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-02-21 | | Release date: | 2006-04-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the human small GTPase GEM
To be Published
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2ZOG
 | | Crystal structure of mouse carnosinase CN2 complexed with ZN and bestatin | | Descriptor: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, Cytosolic non-specific dipeptidase, ZINC ION | | Authors: | Unno, H, Yamashita, T, Okumura, N, Kusunoki, M. | | Deposit date: | 2008-05-14 | | Release date: | 2008-06-10 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural basis for substrate recognition and hydrolysis by mouse carnosinase CN2.
J.Biol.Chem., 283, 2008
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2ZRU
 | | Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with FMN | | Descriptor: | FLAVIN MONONUCLEOTIDE, Isopentenyl-diphosphate delta-isomerase | | Authors: | Unno, H, Yamashita, S, Ikeda, Y, Sekiguchi, S, Yoshida, N, Yoshimura, T, Kusunoki, M, Nakayama, T, Nishino, T, Hemmi, H. | | Deposit date: | 2008-09-01 | | Release date: | 2009-01-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.
J.Biol.Chem., 284, 2009
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2GNQ
 | | Structure of wdr5 | | Descriptor: | CHLORIDE ION, WD-repeat protein 5 | | Authors: | Min, J, Schuetz, A, Allali-Hassani, A, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-04-10 | | Release date: | 2006-06-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
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2GWH
 | | Human Sulfotranferase SULT1C2 in complex with PAP and pentachlorophenol | | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, PENTACHLOROPHENOL, Sulfotransferase 1C2, ... | | Authors: | Tempel, W, Pan, P.W, Dombrovski, L, Allali-Hassani, A, Vedadi, M, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-05-04 | | Release date: | 2006-05-16 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and chemical profiling of the human cytosolic sulfotransferases.
Plos Biol., 5, 2007
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2H9N
 | | WDR5 in complex with monomethylated H3K4 peptide | | Descriptor: | H3 histone, WD-repeat protein 5 | | Authors: | Min, J.R, Schuetz, A, Allali-Hassani, A, Martin, F, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-06-10 | | Release date: | 2006-08-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
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2ZRX
 | | Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with FMN and DMAPP. | | Descriptor: | DIMETHYLALLYL DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, Isopentenyl-diphosphate delta-isomerase, ... | | Authors: | Unno, H, Yamashita, S, Ikeda, Y, Sekiguchi, S, Yoshida, N, Yoshimura, T, Kusunoki, M, Nakayama, T, Nishino, T, Hemmi, H. | | Deposit date: | 2008-09-01 | | Release date: | 2009-01-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.
J.Biol.Chem., 284, 2009
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324D
 | | CRYSTAL STRUCTURES OF D(CCGGGCCM5CGG)-ORTHOGONAL FORM | | Descriptor: | DNA (5'-D(*CP*CP*GP*GP*GP*CP*CP*(5CM)P*GP*G)-3'), SPERMINE | | Authors: | Tippin, D.B, Sundaralingam, M. | | Deposit date: | 1997-03-17 | | Release date: | 1997-05-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Nine polymorphic crystal structures of d(CCGGGCCCGG), d(CCGGGCCm5CGG), d(Cm5CGGGCCm5CGG) and d(CCGGGCC(Br)5CGG) in three different conformations: effects of spermine binding and methylation on the bending and condensation of A-DNA.
J.Mol.Biol., 267, 1997
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377D
 | | 5'-R(*CP*GP*UP*AP*CP*DG)-3' | | Descriptor: | RNA-DNA (5'-R(*CP*GP*UP*AP*CP*DG)-3') | | Authors: | Biswas, R, Mitra, S.N, Sundaralingam, M. | | Deposit date: | 1998-01-26 | | Release date: | 1998-08-10 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | 1.76 A structure of a pyrimidine start alternating A-RNA hexamer r(CGUAC)dG.
Acta Crystallogr.,Sect.D, 54, 1998
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315D
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325D
 | | CRYSTAL STRUCTURES OF D(CM5CGGGCCM5CGG)-HEXAGONAL FORM | | Descriptor: | DNA (5'-D(*CP*(5CM)P*GP*GP*GP*CP*CP*(5CM)P*GP*G)-3') | | Authors: | Tippin, D.B, Sundaralingam, M. | | Deposit date: | 1997-03-17 | | Release date: | 1997-05-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Nine polymorphic crystal structures of d(CCGGGCCCGG), d(CCGGGCCm5CGG), d(Cm5CGGGCCm5CGG) and d(CCGGGCC(Br)5CGG) in three different conformations: effects of spermine binding and methylation on the bending and condensation of A-DNA.
J.Mol.Biol., 267, 1997
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320D
 | | CRYSTAL STRUCTURES OF D(CCGGGCCCGG)-ORTHOGONAL FORM | | Descriptor: | DNA (5'-D(*CP*CP*GP*GP*GP*CP*CP*CP*GP*G)-3'), SPERMINE | | Authors: | Tippin, D.B, Sundaralingam, M. | | Deposit date: | 1997-03-17 | | Release date: | 1997-05-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Nine polymorphic crystal structures of d(CCGGGCCCGG), d(CCGGGCCm5CGG), d(Cm5CGGGCCm5CGG) and d(CCGGGCC(Br)5CGG) in three different conformations: effects of spermine binding and methylation on the bending and condensation of A-DNA.
J.Mol.Biol., 267, 1997
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319D
 | | CRYSTAL STRUCTURES OF D(CCGGG(BR)5CCCGG)-ORTHOGONAL FORM | | Descriptor: | DNA (5'-D(*CP*CP*GP*GP*GP*(CBR)P*CP*CP*GP*G)-3'), THERMINE | | Authors: | Tippin, D.B, Sundaralingam, M. | | Deposit date: | 1997-03-17 | | Release date: | 1997-05-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Nine polymorphic crystal structures of d(CCGGGCCCGG), d(CCGGGCCm5CGG), d(Cm5CGGGCCm5CGG) and d(CCGGGCC(Br)5CGG) in three different conformations: effects of spermine binding and methylation on the bending and condensation of A-DNA.
J.Mol.Biol., 267, 1997
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396D
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375D
 | | A NOVEL END-TO-END BINDING OF TWO NETROPSINS TO THE DNA DECAMER D(CCCCCIIIII)2 | | Descriptor: | DNA (5'-D(*CP*CP*CP*CP*CP*IP*IP*IP*IP*I)-3'), NETROPSIN | | Authors: | Chen, X, Rao, S.T, Sekar, K, Sundaralingam, M. | | Deposit date: | 1998-01-14 | | Release date: | 1998-12-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A Novel End-to-End Binding of Two Netropsins to the DNA Decamers d(CCCCCIIIII) 2, d(CCCBr5CCIIIII)2, d(CBr5CCCCIIIII)2
Nucleic Acids Res., 26, 1998
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323D
 | | CRYSTAL STRUCTURES OF D(CCGGGCCM5CGG)-ORTHOGONAL FORM | | Descriptor: | DNA (5'-D(*CP*CP*GP*GP*GP*CP*CP*(5CM)P*GP*G)-3'), SPERMINE | | Authors: | Tippin, D.B, Sundaralingam, M. | | Deposit date: | 1997-03-17 | | Release date: | 1997-05-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Nine polymorphic crystal structures of d(CCGGGCCCGG), d(CCGGGCCm5CGG), d(Cm5CGGGCCm5CGG) and d(CCGGGCC(Br)5CGG) in three different conformations: effects of spermine binding and methylation on the bending and condensation of A-DNA.
J.Mol.Biol., 267, 1997
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395D
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3AJ7
 | | Crystal Structure of isomaltase from Saccharomyces cerevisiae | | Descriptor: | CALCIUM ION, Oligo-1,6-glucosidase | | Authors: | Yamamoto, K, Miyake, H, Kusunoki, M, Osaki, S. | | Deposit date: | 2010-05-26 | | Release date: | 2010-08-11 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Crystal structures of isomaltase from Saccharomyces cerevisiae and in complex with its competitive inhibitor maltose
Febs J., 277, 2010
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2O1O
 | | Cryptosporidium parvum putative polyprenyl pyrophosphate synthase (cgd4_2550) in complex with risedronate. | | Descriptor: | 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, MAGNESIUM ION, Putative farnesyl pyrophosphate synthase | | Authors: | Chruszcz, M, Artz, J.D, Dong, A, Dunford, J, Lew, J, Zhao, Y, Kozieradski, I, Kavanaugh, K.L, Oppermann, U, Sundstrom, M, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Hui, R, Minor, W, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-11-29 | | Release date: | 2006-12-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis
Chem.Biol., 15, 2008
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2O9K
 | | WDR5 in Complex with Dimethylated H3K4 Peptide | | Descriptor: | H3 HISTONE, WD repeat protein 5 | | Authors: | Min, J.R, Schuetz, A, Allali-Hassani, A, Martin, F, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-12-13 | | Release date: | 2006-12-19 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis for Molecular Recognition and Presentation of Histone H3 by Wdr5.
Embo J., 25, 2006
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2O8P
 | | Crystal structure of a putative 14-3-3 protein from Cryptosporidium parvum, cgd7_2470 | | Descriptor: | 14-3-3 domain containing protein | | Authors: | Dong, A, Lew, J, Wasney, G, Lin, L, Hassanali, A, Zhao, Y, Vedadi, M, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Walker, J.R, Bochkarev, A, Hui, R, Brokx, S.J, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-12-12 | | Release date: | 2007-01-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Characterization of 14-3-3 proteins from Cryptosporidium parvum.
Plos One, 6, 2011
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2IWR
 | | Gtpase Like Domain Of Centaurin Gamma 1 (Human) | | Descriptor: | CENTAURIN GAMMA 1 | | Authors: | Elkins, J.M, Soundararajan, M, Yang, X, Papagrigoriou, E, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Doyle, D.A, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-07-03 | | Release date: | 2006-07-04 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The Centaurin Gamma-1 Gtpase-Like Domain Functions as an Ntpase.
Biochem.J., 401, 2007
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2ODB
 | | The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6) | | Descriptor: | CHLORIDE ION, Human Cell Division Cycle 42 (CDC42), MAGNESIUM ION, ... | | Authors: | Ugochukwu, E, Yang, X, Elkins, J, Soundararajan, M, Pike, A.C.W, Eswaran, J, Burgess, N, Debreczeni, J.E, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Gileadi, O, von Delft, F, Knapp, S, Doyle, D, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-12-22 | | Release date: | 2007-01-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6)
To be Published
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3TB2
 | | 1-Cys peroxidoxin from Plasmodium Yoelli | | Descriptor: | 1,2-ETHANEDIOL, 1-Cys peroxiredoxin, GLYCEROL, ... | | Authors: | Qiu, W, Artz, J.D, Vedadi, M, Sharma, S, Houston, S, Lew, J, Wasney, G, Amani, M, Xu, X, Bray, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Hui, R, Bochkarev, A, Structural Genomics Consortium (SGC) | | Deposit date: | 2011-08-04 | | Release date: | 2011-10-19 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
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2BZG
 | | Crystal structure of thiopurine S-methyltransferase. | | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-ADENOSYL-L-HOMOCYSTEINE, THIOPURINE S-METHYLTRANSFERASE | | Authors: | Battaile, K.P, Wu, H, Zeng, H, Loppnau, P, Dong, A, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | Deposit date: | 2005-08-17 | | Release date: | 2005-08-25 | | Last modified: | 2019-05-15 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Structural Basis of Allele Variation of Human Thiopurine-S-Methyltransferase.
Proteins, 67, 2007
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