6XHS
| Crystal structure of S. aureus TarI in complex with CTP (space group P1211) | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ribitol-5-phosphate cytidylyltransferase 1, ... | Authors: | Li, F.K.K, Strynadka, N.C.J. | Deposit date: | 2020-06-19 | Release date: | 2021-04-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis. J.Struct.Biol., 213, 2021
|
|
6XHR
| Crystal structure of S. aureus TarI (space group P1211) | Descriptor: | Ribitol-5-phosphate cytidylyltransferase 1, THIOCYANATE ION | Authors: | Li, F.K.K, Strynadka, N.C.J. | Deposit date: | 2020-06-19 | Release date: | 2021-04-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis. J.Struct.Biol., 213, 2021
|
|
6XHT
| |
6XFL
| Structural characterization of the type III secretion system pilotin-secretin complex InvH-InvG by NMR spectroscopy | Descriptor: | Type 3 secretion system pilotin, Type 3 secretion system secretin | Authors: | Majewski, D.D, Okon, M, Heinkel, F, Robb, C.S, Vuckovic, M, McIntosh, L.P, Strynadka, N.C.J. | Deposit date: | 2020-06-15 | Release date: | 2020-09-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods. Structure, 29, 2021
|
|
1K0W
| CRYSTAL STRUCTURE OF L-RIBULOSE-5-PHOSPHATE 4-EPIMERASE | Descriptor: | L-RIBULOSE 5 PHOSPHATE 4-EPIMERASE, ZINC ION | Authors: | Luo, Y, Samuel, J, Mosimann, S.C, Lee, J.E, Strynadka, N.C.J. | Deposit date: | 2001-09-21 | Release date: | 2003-01-28 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of L-ribulose-5-phosphate 4-epimerase: an aldolase-like platform for epimerization Biochemistry, 40, 2001
|
|
5BO8
| Structure of human sialyltransferase ST8SiaIII | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ... | Authors: | Volkers, G, Worrall, L, Strynadka, N.C.J. | Deposit date: | 2015-05-27 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation. Nat.Struct.Mol.Biol., 22, 2015
|
|
5BO6
| Structure of human sialyltransferase ST8SiaIII in complex with CDP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Volkers, G, Worrall, L, Strynadka, N.C.J. | Deposit date: | 2015-05-27 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation. Nat.Struct.Mol.Biol., 22, 2015
|
|
5BO7
| Structure of human sialyltransferase ST8SiaIII in complex with CTP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Volkers, G, Worrall, L, Strynadka, N.C.J. | Deposit date: | 2015-05-27 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation. Nat.Struct.Mol.Biol., 22, 2015
|
|
5BO9
| Structure of human sialyltransferase ST8SiaIII in complex with CMP-3FNeu5Ac and Sia-6S-LacNAc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Volkers, G, Worrall, L, Strynadka, N.C.J. | Deposit date: | 2015-05-27 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation. Nat.Struct.Mol.Biol., 22, 2015
|
|
5TW4
| |
5TY7
| Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with nafcillin | Descriptor: | (2R,4S)-2-[(1R)-1-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Penicillin-binding protein 4, SODIUM ION, ... | Authors: | Alexander, J.A.N, Strynadka, N.C.J. | Deposit date: | 2016-11-18 | Release date: | 2018-06-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.894 Å) | Cite: | Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus. J. Biol. Chem., 2018
|
|
5TX9
| Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with ceftobiprole | Descriptor: | (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr rolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Penicillin-binding protein 4, SODIUM ION, ... | Authors: | Alexander, J.A.N, Strynadka, N.C.J. | Deposit date: | 2016-11-16 | Release date: | 2018-05-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus. J. Biol. Chem., 2018
|
|
5TY2
| Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with nafcillin | Descriptor: | (2R,4S)-2-[(1R)-1-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, Penicillin-binding protein 4, ... | Authors: | Alexander, J.A.N, Strynadka, N.C.J. | Deposit date: | 2016-11-18 | Release date: | 2018-06-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus. J. Biol. Chem., 2018
|
|
5TW8
| |
5TXI
| Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with ceftobiprole | Descriptor: | (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr rolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, CHLORIDE ION, GLYCEROL, ... | Authors: | Alexander, J.A.N, Strynadka, N.C.J. | Deposit date: | 2016-11-16 | Release date: | 2018-05-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus. J. Biol. Chem., 2018
|
|
5CUL
| crystal structure of the PscU C-terminal domain | Descriptor: | Translocation protein in type III secretion | Authors: | Bergeron, J.R.C, Strynadka, N.C.J. | Deposit date: | 2015-07-24 | Release date: | 2015-12-02 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The Structure of a Type 3 Secretion System (T3SS) Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing. J.Biol.Chem., 291, 2016
|
|
5CUK
| Crystal structure of the PscP SS domain | Descriptor: | GLYCEROL, Ruler protein | Authors: | Bergeron, J.R.C, Strynadka, N.C.J. | Deposit date: | 2015-07-24 | Release date: | 2015-12-02 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Structure of a Type 3 Secretion System (T3SS) Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing. J.Biol.Chem., 291, 2016
|
|
5WC8
| |
5WC6
| |
5WD7
| Structure of a bacterial polysialyltransferase in complex with fondaparinux | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, SULFATE ION, SiaD | Authors: | Worrall, L.J, Lizak, C, Strynadka, N.C.J. | Deposit date: | 2017-07-04 | Release date: | 2017-08-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid. Sci Rep, 7, 2017
|
|
1SLJ
| Solution structure of the S1 domain of RNase E from E. coli | Descriptor: | Ribonuclease E | Authors: | Schubert, M, Edge, R.E, Lario, P, Cook, M.A, Strynadka, N.C.J, Mackie, G.A, McIntosh, L.P. | Deposit date: | 2004-03-05 | Release date: | 2004-08-17 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Structural characterization of the RNase E S1 domain and identification of its oligonucleotide-binding and dimerization interfaces. J.Mol.Biol., 341, 2004
|
|
1SN8
| Crystal structure of the S1 domain of RNase E from E. coli (Pb derivative) | Descriptor: | LEAD (II) ION, Ribonuclease E | Authors: | Schubert, M, Edge, R.E, Lario, P, Cook, M.A, Strynadka, N.C.J, Mackie, G.A, McIntosh, L.P. | Deposit date: | 2004-03-10 | Release date: | 2004-08-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural characterization of the RNase E S1 domain and identification of its oligonucleotide-binding and dimerization interfaces. J.Mol.Biol., 341, 2004
|
|
1SMX
| Crystal structure of the S1 domain of RNase E from E. coli (native) | Descriptor: | Ribonuclease E | Authors: | Schubert, M, Edge, R.E, Lario, P, Cook, M.A, Strynadka, N.C.J, Mackie, G.A, McIntosh, L.P. | Deposit date: | 2004-03-09 | Release date: | 2004-08-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural characterization of the RNase E S1 domain and identification of its oligonucleotide-binding and dimerization interfaces. J.Mol.Biol., 341, 2004
|
|
2WQP
| Crystal structure of sialic acid synthase NeuB-inhibitor complex | Descriptor: | (2S)-2-hydroxybutanedioic acid, 1,2-ETHANEDIOL, 5-(ACETYLAMINO)-3,5-DIDEOXY-2-O-PHOSPHONO-D-ERYTHRO-L-MANNO-NONONIC ACID, ... | Authors: | Liu, F, Lee, H.J, Strynadka, N.C.J, Tanner, M.E. | Deposit date: | 2009-08-25 | Release date: | 2009-09-15 | Last modified: | 2011-10-12 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The Inhibition of Neisseria Meningitidis Sialic Acid Synthase by a Tetrahedral Intermediate Analog. Biochemistry, 48, 2009
|
|
2WLG
| Crystallographic analysis of the polysialic acid O-acetyltransferase OatWY | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, POLYSIALIC ACID O-ACETYLTRANSFERASE, ... | Authors: | Lee, H.J, Rakic, B, Gilbert, M, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.J. | Deposit date: | 2009-06-23 | Release date: | 2009-06-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Kinetic Characterizations of the Polysialic Acid O-Acetyltransferase Oatwy from Neisseria Meningitidis. J.Biol.Chem., 284, 2009
|
|