5BO9
Structure of human sialyltransferase ST8SiaIII in complex with CMP-3FNeu5Ac and Sia-6S-LacNAc
Summary for 5BO9
Entry DOI | 10.2210/pdb5bo9/pdb |
Related | 5BO6 5BO7 5BO8 |
Descriptor | Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | sialyltransferase, ternary complex, donor, acceptor, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Golgi apparatus membrane ; Single-pass type II membrane protein : O43173 |
Total number of polymer chains | 2 |
Total formula weight | 81544.01 |
Authors | Volkers, G.,Worrall, L.,Strynadka, N.C.J. (deposition date: 2015-05-27, release date: 2015-07-15, Last modification date: 2023-09-27) |
Primary citation | Volkers, G.,Worrall, L.J.,Kwan, D.H.,Yu, C.C.,Baumann, L.,Lameignere, E.,Wasney, G.A.,Scott, N.E.,Wakarchuk, W.,Foster, L.J.,Withers, S.G.,Strynadka, N.C. Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation. Nat.Struct.Mol.Biol., 22:627-635, 2015 Cited by PubMed: 26192331DOI: 10.1038/nsmb.3060 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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