5BO9

Structure of human sialyltransferase ST8SiaIII in complex with CMP-3FNeu5Ac and Sia-6S-LacNAc

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006486	biological_process	protein glycosylation
A	0008373	molecular_function	sialyltransferase activity
B	0006486	biological_process	protein glycosylation
B	0008373	molecular_function	sialyltransferase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton donor/acceptor => ECO:0000305|PubMed:26192331

Chain	Residue	Details
A	HIS354
B	HIS354

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site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000305|PubMed:26192331, ECO:0007744|PDB:5BO9

Chain	Residue	Details
A	SER300
B	ASN167
B	ASN190
B	SER300
B	THR301
B	GLY302
B	TRP322
B	TYR336
B	HIS337
A	ASN190
A	THR301
A	GLY302
A	TRP322
A	TYR336
A	HIS337
A	ASN167

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site_id	SWS_FT_FI3
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:26192331, ECO:0000269|Ref.7, ECO:0007744|PDB:5BO6, ECO:0007744|PDB:5BO8, ECO:0007744|PDB:5BO9, ECO:0007744|PDB:5CXY

Chain	Residue	Details
A	ASN93
B	ASN93

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site_id	SWS_FT_FI4
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:26192331, ECO:0007744|PDB:5BO9

Chain	Residue	Details
A	ASN113
B	ASN113

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site_id	SWS_FT_FI5
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:26192331, ECO:0000269|Ref.7, ECO:0007744|PDB:5BO6, ECO:0007744|PDB:5BO7, ECO:0007744|PDB:5BO9, ECO:0007744|PDB:5CXY

Chain	Residue	Details
A	ASN160
B	ASN160

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site_id	SWS_FT_FI6
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255, ECO:0000269|PubMed:26192331, ECO:0007744|PDB:5BO6, ECO:0007744|PDB:5BO7, ECO:0007744|PDB:5BO8, ECO:0007744|PDB:5BO9, ECO:0007744|PDB:5CXY

Chain	Residue	Details
A	ASN206
B	ASN206

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