3BZZ
 
 | | Crystal structural of the mutated R313T EscU/SpaS C-terminal domain | | 分子名称: | EscU | | 著者 | Zarivach, R, Deng, W, Vuckovic, M, Felise, H.B, Nguyen, H.V, Miller, S.I, Finlay, B.B, Strynadka, N.C.J. | | 登録日 | 2008-01-18 | | 公開日 | 2008-04-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.407 Å) | | 主引用文献 | Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
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6PEE
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3BZO
 | | Crystal structural of native EscU C-terminal domain | | 分子名称: | EscU, SULFATE ION | | 著者 | Zarivach, R, Deng, W, Vuckovic, M, Felise, H.B, Nguyen, H.V, Miller, S.I, Finlay, B.B, Strynadka, N.C.J. | | 登録日 | 2008-01-18 | | 公開日 | 2008-04-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
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3BZV
 | | Crystal structural of the mutated T264A EscU C-terminal domain | | 分子名称: | EscU | | 著者 | Zarivach, R, Deng, W, Vuckovic, M, Felise, H.B, Nguyen, H.V, Miller, S.I, Finlay, B.B, Strynadka, N.C.J. | | 登録日 | 2008-01-18 | | 公開日 | 2008-04-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
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6PEM
 | | Focussed refinement of InvGN0N1:SpaPQR:PrgHK from Salmonella SPI-1 injectisome NC-base | | 分子名称: | Lipoprotein PrgK, Protein InvG, Protein PrgH, ... | | 著者 | Hu, J, Worrall, L.J, Strynadka, N.C.J. | | 登録日 | 2019-06-20 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
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3T0T
 | | Crystal structure of S. aureus Pyruvate Kinase | | 分子名称: | N'-[(1E)-1-(1H-benzimidazol-2-yl)ethylidene]-5-bromo-2-hydroxybenzohydrazide, PHOSPHATE ION, Pyruvate kinase | | 著者 | Worrall, L.J, Vuckovic, M, Strynadka, N.C.J. | | 登録日 | 2011-07-20 | | 公開日 | 2012-06-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Cheminformatics-driven discovery of selective, nanomolar inhibitors for staphylococcal pyruvate kinase.
Acs Chem.Biol., 7, 2012
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6Q15
 | | Structure of the Salmonella SPI-1 injectisome needle complex | | 分子名称: | Lipoprotein PrgK, Protein InvG, Protein PrgH, ... | | 著者 | Hu, J, Worrall, L.J, Strynadka, N.C.J. | | 登録日 | 2019-08-02 | | 公開日 | 2019-10-23 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (5.15 Å) | | 主引用文献 | T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
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6Q14
 | | Structure of the Salmonella SPI-1 injectisome NC-base | | 分子名称: | Lipoprotein PrgK, Protein InvG, Protein PrgH, ... | | 著者 | Hu, J, Worrall, L.J, Strynadka, N.C.J. | | 登録日 | 2019-08-02 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
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6Q16
 | | Focussed refinement of InvGN0N1:PrgHK:SpaPQR:PrgIJ from Salmonella SPI-1 injectisome NC-base | | 分子名称: | Lipoprotein PrgK, Protein InvG, Protein PrgH, ... | | 著者 | Hu, J, Worrall, L.J, Strynadka, N.C.J. | | 登録日 | 2019-08-02 | | 公開日 | 2019-10-23 | | 最終更新日 | 2020-01-15 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
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3UJZ
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4G2S
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4G1I
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4DKI
 | | Structural Insights into the Anti- Methicillin-Resistant Staphylococcus aureus (MRSA) Activity of Ceftobiprole | | 分子名称: | (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr rolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, BICARBONATE ION, CADMIUM ION, ... | | 著者 | Lovering, A.L, Gretes, M.C, Strynadka, N.C.J. | | 登録日 | 2012-02-03 | | 公開日 | 2012-08-01 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural Insights into the Anti-methicillin-resistant Staphylococcus aureus (MRSA) Activity of Ceftobiprole.
J.Biol.Chem., 287, 2012
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6N7O
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6NJO
 | | Structure of the assembled ATPase EscN from the enteropathogenic E. coli (EPEC) type III secretion system | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | 著者 | Majewski, D.D, Worrall, L.J, Hong, C, Atkinson, C.E, Vuckovic, M, Watanabe, N, Yu, Z, Strynadka, N.C.J. | | 登録日 | 2019-01-03 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | | 主引用文献 | Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry.
Nat Commun, 10, 2019
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6NTZ
 | | Crystal structure of E. coli PBP5-meropenem | | 分子名称: | (2S,3R,4S)-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, D-alanyl-D-alanine carboxypeptidase | | 著者 | Caveney, N.A, Strynadka, N.C.J, Caballero, G, Worrall, L.J. | | 登録日 | 2019-01-30 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli.
Nat Commun, 10, 2019
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6NTW
 | | Crystal structure of E. coli YcbB | | 分子名称: | (2S,3R,4S)-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Probable L,D-transpeptidase YcbB, SULFATE ION | | 著者 | Caveney, N.A, Strynadka, N.C.J, Caballero, G, Worrall, L.J. | | 登録日 | 2019-01-30 | | 公開日 | 2019-03-20 | | 最終更新日 | 2020-01-08 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli.
Nat Commun, 10, 2019
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6O9S
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6NJP
 | | Structure of the assembled ATPase EscN in complex with its central stalk EscO from the enteropathogenic E. coli (EPEC) type III secretion system | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, EscO, ... | | 著者 | Majewski, D.D, Worrall, L.J, Hong, C, Atkinson, C.E, Vuckovic, M, Watanabe, N, Yu, Z, Strynadka, N.C.J. | | 登録日 | 2019-01-03 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | | 主引用文献 | Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry.
Nat Commun, 10, 2019
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6O9W
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4G08
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1VQQ
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2QF5
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5FA7
 | | CTX-M-15 in complex with FPI-1523 | | 分子名称: | Beta-lactamase, [[(3~{R},6~{S})-6-(acetamidocarbamoyl)-1-methanoyl-piperidin-3-yl]amino] hydrogen sulfate | | 著者 | King, A.M, King, D.T, French, S, Brouillette, E, Asli, A, Alexander, A.N, Vuckovic, M, Maiti, S.N, Parr, T.R, Brown, E.D, Malouin, F, Strynadka, N.C.J, Wright, G.D. | | 登録日 | 2015-12-11 | | 公開日 | 2016-01-20 | | 最終更新日 | 2019-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-beta-Lactamases and Penicillin-Binding Proteins.
Acs Chem.Biol., 11, 2016
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2QF4
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