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PDB: 283 件
3G6E
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BU of 3g6e by Molmil
Co-crystal structure of Homoharringtonine bound to the large ribosomal subunit
分子名称: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 23S ribosomal RNA, 50S ribosomal protein L10E, ...
著者Gurel, G, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2009-02-06
公開日2009-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
J.Mol.Biol., 389, 2009
3HL2
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BU of 3hl2 by Molmil
The crystal structure of the human SepSecS-tRNASec complex
分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, Monothiophosphate, O-phosphoseryl-tRNA(Sec) selenium transferase, ...
著者Palioura, S, Steitz, T.A, Soll, D, Simonovic, M.
登録日2009-05-26
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献The human SepSecS-tRNASec complex reveals the mechanism of selenocysteine formation.
Science, 325, 2009
3I55
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BU of 3i55 by Molmil
Co-crystal structure of Mycalamide A Bound to the Large Ribosomal Subunit
分子名称: 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Gurel, G, Blaha, G, Steitz, T.A, Moore, P.B.
登録日2009-07-03
公開日2010-03-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Structures of triacetyloleandomycin and mycalamide A bind to the large ribosomal subunit of Haloarcula marismortui.
Antimicrob.Agents Chemother., 53, 2009
3G71
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BU of 3g71 by Molmil
Co-crystal structure of Bruceantin bound to the large ribosomal subunit
分子名称: 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Gurel, G, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2009-02-09
公開日2009-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
J.Mol.Biol., 389, 2009
3G4S
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BU of 3g4s by Molmil
Co-crystal structure of Tiamulin bound to the large ribosomal subunit
分子名称: 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L10e, ...
著者Gurel, G, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2009-02-04
公開日2009-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
J.Mol.Biol., 389, 2009
5J4C
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BU of 5j4c by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (soaked) and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S.
登録日2016-03-31
公開日2016-04-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome.
Nucleic Acids Res., 44, 2016
5J4B
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BU of 5j4b by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (co-crystallized) and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S.
登録日2016-03-31
公開日2016-04-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome.
Nucleic Acids Res., 44, 2016
5J8B
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BU of 5j8b by Molmil
Crystal structure of Elongation Factor 4 (EF-4/LepA) in complex with GDPCP bound to the Thermus thermophilus 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Gagnon, M.G, Lin, J, Steitz, T.A.
登録日2016-04-07
公開日2016-05-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Elongation factor 4 remodels the A-site tRNA on the ribosome.
Proc.Natl.Acad.Sci.USA, 113, 2016
3OVB
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BU of 3ovb by Molmil
How the CCA-adding Enzyme Selects Adenine over Cytosine in Position 76 of tRNA
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CCA-Adding Enzyme, ...
著者Pan, B.C, Xiong, Y, Steitz, T.A.
登録日2010-09-16
公開日2010-12-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献How the CCA-Adding Enzyme Selects Adenine over Cytosine at Position 76 of tRNA.
Science, 330, 2010
1FFK
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BU of 1ffk by Molmil
CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM HALOARCULA MARISMORTUI AT 2.4 ANGSTROM RESOLUTION
分子名称: 23S RRNA, 5S RRNA, CADMIUM ION, ...
著者Ban, N, Nissen, P, Hansen, J, Moore, P.B, Steitz, T.A.
登録日2000-07-25
公開日2000-08-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The complete atomic structure of the large ribosomal subunit at 2.4 A resolution.
Science, 289, 2000
4KJZ
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BU of 4kjz by Molmil
Crystal Structure of Thermus Thermophilus IF2, Apo and GDP-bound Forms (2-474)
分子名称: GUANOSINE-5'-DIPHOSPHATE, Translation initiation factor IF-2
著者Eiler, D.R, Lin, J, Steitz, T.A.
登録日2013-05-04
公開日2013-09-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Initiation factor 2 crystal structure reveals a different domain organization from eukaryotic initiation factor 5B and mechanism among translational GTPases.
Proc.Natl.Acad.Sci.USA, 110, 2013
5IPM
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BU of 5ipm by Molmil
SigmaS-transcription initiation complex with 4-nt nascent RNA
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Liu, B, Zuo, Y, Steitz, T.A.
登録日2016-03-09
公開日2016-03-30
最終更新日2016-06-22
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IPN
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BU of 5ipn by Molmil
SigmaS-transcription initiation complex with 4-nt nascent RNA
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Liu, B, Zuo, Y, Steitz, T.A.
登録日2016-03-09
公開日2016-03-30
最終更新日2016-06-22
実験手法X-RAY DIFFRACTION (4.61 Å)
主引用文献Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
3OVS
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BU of 3ovs by Molmil
How the CCA-adding Enzyme Selects Adenine over Cytosine in Position 76 of tRNA
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CCA-Adding Enzyme, ...
著者Pan, B.C, Xiong, Y, Steitz, T.A.
登録日2010-09-17
公開日2010-12-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献How the CCA-Adding Enzyme Selects Adenine over Cytosine at Position 76 of tRNA.
Science, 330, 2010
1WAF
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BU of 1waf by Molmil
DNA POLYMERASE FROM BACTERIOPHAGE RB69
分子名称: DNA POLYMERASE, GUANOSINE
著者Wang, J, Satter, A.K.M.A, Wang, C.C, Karam, J.D, Konigsberg, W.H, Steitz, T.A.
登録日1997-04-13
公開日1998-01-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69.
Cell(Cambridge,Mass.), 89, 1997
1WAJ
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BU of 1waj by Molmil
DNA POLYMERASE FROM BACTERIOPHAGE RB69
分子名称: DNA POLYMERASE, GUANOSINE-5'-MONOPHOSPHATE
著者Wang, J, Satter, A.K.M.A, Wang, C.C, Karam, J.D, Konigsberg, W.H, Steitz, T.A.
登録日1997-04-13
公開日1998-01-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69.
Cell(Cambridge,Mass.), 89, 1997
5IPL
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BU of 5ipl by Molmil
SigmaS-transcription initiation complex with 4-nt nascent RNA
分子名称: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Zuo, Y, Steitz, T.A.
登録日2016-03-09
公開日2016-03-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
4M4W
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BU of 4m4w by Molmil
Mechanistic implications for the bacterial primosome assembly of the structure of a helicase-helicase loader complex
分子名称: DNA primase, Primosomal protein DnaI, Replicative helicase
著者Liu, B, Eliason, W.K, Steitz, T.A.
登録日2013-08-07
公開日2013-09-25
最終更新日2013-10-02
実験手法X-RAY DIFFRACTION (6.1 Å)
主引用文献Structure of a helicase-helicase loader complex reveals insights into the mechanism of bacterial primosome assembly.
Nat Commun, 4, 2013
1YI2
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BU of 1yi2 by Molmil
Crystal Structure Of Erythromycin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui
分子名称: 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ...
著者Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2005-01-11
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121, 2005
1YIJ
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BU of 1yij by Molmil
Crystal Structure Of Telithromycin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui
分子名称: 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ...
著者Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2005-01-12
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121, 2005
1YJ9
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BU of 1yj9 by Molmil
Crystal Structure Of The Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui Containing a three residue deletion in L22
分子名称: 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ...
著者Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2005-01-13
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121, 2005
1YJN
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BU of 1yjn by Molmil
Crystal Structure Of Clindamycin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui
分子名称: 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ...
著者Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2005-01-14
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121, 2005
1CEZ
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BU of 1cez by Molmil
CRYSTAL STRUCTURE OF A T7 RNA POLYMERASE-T7 PROMOTER COMPLEX
分子名称: DNA (5'-D(P*TP*AP*AP*TP*AP*CP*GP*AP*CP*TP*CP*AP*CP*TP*A)-3'), DNA (5'-D(P*TP*AP*TP*AP*GP*TP*GP*AP*GP*TP*CP*GP*TP*AP*TP*TP*A)-3'), PROTEIN (BACTERIOPHAGE T7 RNA POLYMERASE)
著者Cheetham, G.M.T, Jeruzalmi, D, Steitz, T.A.
登録日1999-03-11
公開日1999-05-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for initiation of transcription from an RNA polymerase-promoter complex.
Nature, 399, 1999
2HPI
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BU of 2hpi by Molmil
Eubacterial and Eukaryotic Replicative DNA Polymerases are not Homologous: X-ray Structure of DNA Polymerase III
分子名称: CHLORIDE ION, DNA polymerase III alpha subunit, MAGNESIUM ION, ...
著者Bailey, S, Wing, R.A, Steitz, T.A.
登録日2006-07-17
公開日2006-09-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases.
Cell(Cambridge,Mass.), 126, 2006
2HPM
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BU of 2hpm by Molmil
Eubacterial and Eukaryotic Replicative DNA Polymerases are not Homologous: X-ray Structure of DNA Polymerase III
分子名称: CHLORIDE ION, DNA Polymerase III alpha subunit, MAGNESIUM ION, ...
著者Bailey, S, Wing, R.A, Steitz, T.A.
登録日2006-07-17
公開日2006-09-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases.
Cell(Cambridge,Mass.), 126, 2006

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