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PDB: 71 件
7P59
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Variant Surface Glycoprotein 3 (VSG3, MiTat1.3, VSG224) with two O-linked post-translational modifications
分子名称: Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Gkeka, A, Arest-Branco, F, Stebbins, C.E, Papavasiliou, F.N.
登録日2021-07-14
公開日2022-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Immunodominant surface epitopes power immune evasion in the African trypanosome.
Cell Rep, 42, 2023
7P5B
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Variant Surface Glycoprotein 3 (VSG3, MiTat1.3, VSG224) mutant (serine 319 to alanine), single O-linked glycosylated at Ser317
分子名称: Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Gkeka, A, Aresta-Branco, F, Stebbins, C.E, Papavasiliou, F.N.
登録日2021-07-14
公開日2022-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Immunodominant surface epitopes power immune evasion in the African trypanosome.
Cell Rep, 42, 2023
7P5A
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BU of 7p5a by Molmil
Variant Surface Glycoprotein 3 (VSG3, MiTat1.3, VSG224) mutant (serine 317 to alanine), single O-linked glycosylated at Ser319
分子名称: Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Gkeka, A, Aresta-Branco, F, Stebbins, C.E, Papavasiliou, F.N.
登録日2021-07-14
公開日2022-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Immunodominant surface epitopes power immune evasion in the African trypanosome.
Cell Rep, 42, 2023
8Q0P
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Crystal Structure of an N-terminal Domain of Variant Surface Glycoprotein 21 (VSG21) of Trypanosome brucei brucei Lister 427
分子名称: Variant surface glycoprotein MITat 1.21
著者Zeelen, J.P, Stebbins, C.E.
登録日2023-07-28
公開日2023-09-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
8Q0E
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Crystal Structure of the N-terminal Domain of Variant Surface Glycoprotein 545 (VSG545) of Trypanosome brucei brucei Lister 427
分子名称: Variant surface glycoprotein 545
著者van Straaten, M, Stebbins, C.E.
登録日2023-07-28
公開日2023-09-13
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
4YX7
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BU of 4yx7 by Molmil
Complex of SpaO(SPOA1,2) and OrgB(APAR)::T4lysozyme fusion protein
分子名称: Oxygen-regulated invasion protein OrgB,Endolysin, Surface presentation of antigens protein SpaO
著者Notti, R.Q, Stebbins, C.E.
登録日2015-03-22
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.0007 Å)
主引用文献A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
4YX1
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SpaO(SPOA2)
分子名称: CALCIUM ION, Surface presentation of antigens protein SpaO
著者Notti, R.Q, Stebbins, C.E.
登録日2015-03-21
公開日2015-06-03
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
4YXC
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Complex of FliM(SPOA)::FliN fusion protein and FliH(APAR)::T4lysozyme fusion protein
分子名称: Flagellar assembly protein H,Endolysin, Flagellar motor switch protein FliM,Flagellar motor switch protein FliN
著者Notti, R.Q, Stebbins, C.E.
登録日2015-03-23
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
4YXB
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FliM(SPOA)::FliN fusion protein
分子名称: Ambiguous peptide density, Flagellar motor switch protein FliM,Flagellar motor switch protein FliN, FliM::FliN fragment, ...
著者Notti, R.Q, Stebbins, C.E.
登録日2015-03-22
公開日2015-06-03
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
4YXA
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Complex of SpaO(SPOA1,2 SeMet) and OrgB(APAR)::T4lysozyme fusion protein
分子名称: Oxygen-regulated invasion protein OrgB,Endolysin, Surface presentation of antigens protein SpaO
著者Notti, R.Q, Stebbins, C.E.
登録日2015-03-22
公開日2015-06-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
6Z7C
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Variant Surface Glycoprotein VSGsur mutant H122A
分子名称: Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zeelen, J.P, Straaten van, M, Stebbins, C.E.
登録日2020-05-30
公開日2021-03-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
6Z7B
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Variant Surface Glycoprotein VSGsur bound to suramin
分子名称: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zeelen, J.P, Straaten van, M, Stebbins, C.E, Jeffrey, P.
登録日2020-05-30
公開日2021-03-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
6Z7E
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Variant Surface Glycoprotein VSGsur mutant H122A soaked in 7.7 mM suramin
分子名称: Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zeelen, J.P, Straaten van, M, Stebbins, C.E.
登録日2020-05-30
公開日2021-03-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.663 Å)
主引用文献Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
6Z7D
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Variant Surface Glycoprotein VSGsur mutant H122A soaked in 0.77 mM Suramin.
分子名称: Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zeelen, J.P, Straaten van, M, Stebbins, C.E.
登録日2020-05-30
公開日2021-03-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
6Z79
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Variant Surface Glycoprotein VSGsur, I3C ("Magic Triangle") derivative used for phasing of the structure and subsequently as a model for molecular replacement of native, mutants, and drug soaks.
分子名称: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zeelen, J.P, Straaten van, M, Stebbins, C.E.
登録日2020-05-30
公開日2021-03-17
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structure of trypanosome coat protein VSGsur and function in suramin resistance.
Nat Microbiol, 6, 2021
6Z7A
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Variant Surface Glycoprotein VSGsur
分子名称: Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zeelen, J.P, Straaten van, M, Stebbins, C.E, Hashemi, H.
登録日2020-05-30
公開日2021-05-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献A Parasite Coat Protein Binds Suramin to Confer Drug Resistance
Nat Microbiol, 6, 2021
2FD4
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Crystal Structure of AvrPtoB (436-553)
分子名称: avirulence protein AvrptoB
著者Janjusevic, R, Stebbins, C.E.
登録日2005-12-13
公開日2005-12-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A bacterial inhibitor of host programmed cell death defenses is an E3 ubiquitin ligase.
Science, 311, 2006
2FM9
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Structure of Salmonella SipA residues 48-264
分子名称: Cell invasion protein sipA
著者Lilic, M, Vujanac, M, Stebbins, C.E.
登録日2006-01-08
公開日2006-03-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A common structural motif in the binding of virulence factors to bacterial secretion chaperones.
Mol.Cell, 21, 2006
2FM8
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Crystal Structure of the Salmonella Secretion Chaperone InvB in Complex with SipA
分子名称: Cell invasion protein sipA, Surface presentation of antigens protein spaK
著者Lilic, M, Vujanac, M, Stebbins, C.E.
登録日2006-01-08
公開日2006-03-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A common structural motif in the binding of virulence factors to bacterial secretion chaperones.
Mol.Cell, 21, 2006
2H7O
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Crystal structure of the Rho-GTPase binding domain of YpkA
分子名称: Protein kinase ypkA
著者Prehna, G, Ivanov, M, Bliska, J.B, Stebbins, C.E.
登録日2006-06-02
公開日2006-09-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Yersinia virulence depends on mimicry of host rho-family nucleotide dissociation inhibitors.
Cell(Cambridge,Mass.), 126, 2006
2H7V
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Co-crystal structure of YpkA-Rac1
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Migration-inducing protein 5, ...
著者Prehna, G, Ivanov, M, Bliska, J.B, Stebbins, C.E.
登録日2006-06-04
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Yersinia virulence depends on mimicry of host rho-family nucleotide dissociation inhibitors.
Cell(Cambridge,Mass.), 126, 2006
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