6DBH
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![BU of 6dbh by Molmil](/molmil-images/mine/6dbh) | Crystal structure of PPAR gamma in complex with NMP422 | Descriptor: | 4-{2-[(2,3-dioxo-1-pentyl-2,3-dihydro-1H-indol-5-yl)sulfanyl]ethyl}benzoic acid, CHLORIDE ION, Peroxisome proliferator-activated receptor gamma | Authors: | Mou, T.C, Chrisman, I.M, Hughes, T.S, Sprang, S.R. | Deposit date: | 2018-05-03 | Release date: | 2019-05-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.597 Å) | Cite: | Crystal structure of PPAR gamma in complex with NMP422 To Be Published
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2GVD
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![BU of 2gvd by Molmil](/molmil-images/mine/2gvd) | |
2GVZ
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![BU of 2gvz by Molmil](/molmil-images/mine/2gvz) | |
6XAZ
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6XAX
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![BU of 6xax by Molmil](/molmil-images/mine/6xax) | Structure of a fragment of human fibronectin containing the 11th type III domain, extra domain A, and the 12th type III domain | Descriptor: | Fibronectin, GLYCEROL | Authors: | Mou, T.C, Nepomuceno, P.A, Sprang, S.R, Briknarova, K. | Deposit date: | 2020-06-04 | Release date: | 2021-06-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Fragment of human fibronectin containing the 11th type III domain, extra domain A, and 12th type III domain To Be Published
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6XAY
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![BU of 6xay by Molmil](/molmil-images/mine/6xay) | Structure of a fragment of human fibronectin containing the 10th, 11th and 12th type III domains | Descriptor: | Fibronectin, GLYCEROL | Authors: | Mou, T.C, Nepomuceno, P.A, Sprang, S.R, Briknarova, K. | Deposit date: | 2020-06-05 | Release date: | 2021-06-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Fragment of human fibronectin containing the 10th, 11th and 12th type III domains To Be Published
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5I57
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![BU of 5i57 by Molmil](/molmil-images/mine/5i57) | Glutamate- and glycine-bound GluN1/GluN2A agonist binding domains | Descriptor: | GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ... | Authors: | Mou, T.-C, Sprang, S.R, Hansen, K.B. | Deposit date: | 2016-02-14 | Release date: | 2016-09-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors. Neuron, 91, 2016
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5I58
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![BU of 5i58 by Molmil](/molmil-images/mine/5i58) | GLUTAMATE- AND GLYCINE-BOUND GLUN1/GLUN2A AGONIST BINDING DOMAINS WITH MPX-004 | Descriptor: | 5-({[(3-chloro-4-fluorophenyl)sulfonyl]amino}methyl)-N-[(2-methyl-1,3-thiazol-5-yl)methyl]pyrazine-2-carboxamide, GLUTAMIC ACID, GLYCINE, ... | Authors: | Mou, T.-C, Sprang, S.R, Hansen, K.B. | Deposit date: | 2016-02-14 | Release date: | 2016-09-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors. Neuron, 91, 2016
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5JTY
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![BU of 5jty by Molmil](/molmil-images/mine/5jty) | Glutamate- and DCKA-bound GluN1/GluN2A agonist binding domains with MPX-007 | Descriptor: | 4-hydroxy-5,7-dimethylquinoline-2-carboxylic acid, 5-({[(3,4-difluorophenyl)sulfonyl]amino}methyl)-6-methyl-N-[(2-methyl-1,3-thiazol-5-yl)methyl]pyrazine-2-carboxamide, GLUTAMIC ACID, ... | Authors: | Mou, T.-C, Sprang, S.R, Hansen, K.B. | Deposit date: | 2016-05-10 | Release date: | 2016-09-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors. Neuron, 91, 2016
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6MSV
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6MFA
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5DF0
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![BU of 5df0 by Molmil](/molmil-images/mine/5df0) | Crystal structure of AcMNPV Chitinase A in complex WITH CHITOTRIO-THIAZOLINE DITHIOAMIDE | Descriptor: | (2R,3aR,5R,6R,7R,7aR)-5-(hydroxymethyl)-2-methylhexahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-2-(ethanethioylamino)-beta-D-glucopyranose, ... | Authors: | Mou, T.-C, Sprang, S.R. | Deposit date: | 2015-08-26 | Release date: | 2016-09-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.251 Å) | Cite: | Crystal structure of AcMNPV Chitinase A To Be Published
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3ODX
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3ODO
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3ODW
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5T7H
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![BU of 5t7h by Molmil](/molmil-images/mine/5t7h) | Crystal structure of dimeric yeast iso-1-cytochrome C with CYMAL6 | Descriptor: | 6-cyclohexylhexan-1-ol, Cytochrome c iso-1, HEME C, ... | Authors: | Mcclelland, L, Mou, T.C, Sprang, S.R, Bowler, B.E. | Deposit date: | 2016-09-05 | Release date: | 2017-03-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Cytochrome c Can Form a Well-Defined Binding Pocket for Hydrocarbons. J. Am. Chem. Soc., 138, 2016
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6MM1
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![BU of 6mm1 by Molmil](/molmil-images/mine/6mm1) | Structure of the cysteine-rich region from human EHMT2 | Descriptor: | Histone-lysine N-methyltransferase EHMT2, ZINC ION | Authors: | Kerchner, K.M, Mou, T.C, Sprang, S.R, Briknarova, K. | Deposit date: | 2018-09-28 | Release date: | 2019-10-02 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structure of the cysteine-rich region from human histone-lysine N-methyltransferase EHMT2 (G9a). J Struct Biol X, 5, 2021
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6NMG
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![BU of 6nmg by Molmil](/molmil-images/mine/6nmg) | Crystal Structure of Rat Ric-8A G alpha binding domain | Descriptor: | Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans), SULFATE ION | Authors: | Zeng, B, Mou, T.C, Sprang, S.R. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure, Function, and Dynamics of the G alpha Binding Domain of Ric-8A. Structure, 27, 2019
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3P6A
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![BU of 3p6a by Molmil](/molmil-images/mine/3p6a) | |
5DEZ
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![BU of 5dez by Molmil](/molmil-images/mine/5dez) | Crystal structure of AcMNPV Chitinase A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ac-ChiA, ... | Authors: | Mou, T.-C, Sprang, S.R. | Deposit date: | 2015-08-26 | Release date: | 2016-09-07 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of AcMNPV Chitinase A To Be Published
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5DFT
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6NMJ
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![BU of 6nmj by Molmil](/molmil-images/mine/6nmj) | Crystal Structure of Rat Ric-8A G alpha binding domain, "Paratone-N Immersed" | Descriptor: | Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) | Authors: | Zeng, B, Mou, T.C, Sprang, S.R. | Deposit date: | 2019-01-11 | Release date: | 2019-06-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure, Function, and Dynamics of the G alpha Binding Domain of Ric-8A. Structure, 27, 2019
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3C15
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3C16
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![BU of 3c16 by Molmil](/molmil-images/mine/3c16) | |
3C14
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![BU of 3c14 by Molmil](/molmil-images/mine/3c14) | |