6SA5
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![BU of 6sa5 by Molmil](/molmil-images/mine/6sa5) | SALSA / DMBT1 / GP340 SRCR domain 8 | Descriptor: | Deleted in malignant brain tumors 1 protein, GLYCEROL, MAGNESIUM ION, ... | Authors: | Reichhardt, M.P, Johnson, S, Loimaranta, V, Lea, S.M. | Deposit date: | 2019-07-16 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR fold. Life Sci Alliance, 3, 2020
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5TIS
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![BU of 5tis by Molmil](/molmil-images/mine/5tis) | Room temperature XFEL structure of the native, doubly-illuminated photosystem II complex | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | Authors: | Young, I.D, Ibrahim, M, Chatterjee, R, Gul, S, Fuller, F, Koroidov, S, Brewster, A.S, Tran, R, Alonso-Mori, R, Kroll, T, Michels-Clark, T, Laksmono, H, Sierra, R.G, Stan, C.A, Hussein, R, Zhang, M, Douthit, L, Kubin, M, de Lichtenberg, C, Pham, L.V, Nilsson, H, Cheah, M.H, Shevela, D, Saracini, C, Bean, M.A, Seuffert, I, Sokaras, D, Weng, T.-C, Pastor, E, Weninger, C, Fransson, T, Lassalle, L, Braeuer, P, Aller, P, Docker, P.T, Andi, B, Orville, A.M, Glownia, J.M, Nelson, S, Sikorski, M, Zhu, D, Hunter, M.S, Aquila, A, Koglin, J.E, Robinson, J, Liang, M, Boutet, S, Lyubimov, A.Y, Uervirojnangkoorn, M, Moriarty, N.W, Liebschner, D, Afonine, P.V, Watermann, D.G, Evans, G, Wernet, P, Dobbek, H, Weis, W.I, Brunger, A.T, Zwart, P.H, Adams, P.D, Zouni, A, Messinger, J, Bergmann, U, Sauter, N.K, Kern, J, Yachandra, V.K, Yano, J. | Deposit date: | 2016-10-03 | Release date: | 2016-11-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.25000381 Å) | Cite: | Structure of photosystem II and substrate binding at room temperature. Nature, 540, 2016
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4YAA
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![BU of 4yaa by Molmil](/molmil-images/mine/4yaa) | YopH W354Y Yersinia enterocolitica PTPase apo form | Descriptor: | ACETATE ION, SULFATE ION, Tyrosine-protein phosphatase YopH | Authors: | Moise, G.E, Johnson, S.J, Hengge, A.C. | Deposit date: | 2015-02-17 | Release date: | 2015-10-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Conservative Tryptophan Mutants of the Protein Tyrosine Phosphatase YopH Exhibit Impaired WPD-Loop Function and Crystallize with Divanadate Esters in Their Active Sites. Biochemistry, 54, 2015
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7M4H
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![BU of 7m4h by Molmil](/molmil-images/mine/7m4h) | DNA Polymerase Lambda, dCTP:At Mn2+ Reaction State Ternary Complex, 225 min | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3'), ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2021-03-21 | Release date: | 2022-07-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.923 Å) | Cite: | Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
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7M4F
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![BU of 7m4f by Molmil](/molmil-images/mine/7m4f) | DNA Polymerase Lambda, dCTP:At Mg2+ Product State Ternary Complex, 300 min | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2021-03-21 | Release date: | 2022-07-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.947 Å) | Cite: | Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
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7M4J
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![BU of 7m4j by Molmil](/molmil-images/mine/7m4j) | DNA Polymerase Lambda, dCTP:At Mn2+ Product State Ternary Complex, 960 min | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2021-03-21 | Release date: | 2022-07-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.377 Å) | Cite: | Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
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7M4E
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![BU of 7m4e by Molmil](/molmil-images/mine/7m4e) | DNA Polymerase Lambda, dCTP:At Mg2+ Reaction State Ternary Complex, 120 min | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3'), ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2021-03-21 | Release date: | 2022-07-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.903 Å) | Cite: | Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
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7M46
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![BU of 7m46 by Molmil](/molmil-images/mine/7m46) | DNA Polymerase Lambda, TTP:At Mg2+ Product State Ternary Complex, 5 min | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2021-03-21 | Release date: | 2022-07-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
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7M4G
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![BU of 7m4g by Molmil](/molmil-images/mine/7m4g) | DNA Polymerase Lambda, dCTP:At Mg2+ Product State Ternary Complex, 960 min | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2021-03-21 | Release date: | 2022-07-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
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7M4D
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![BU of 7m4d by Molmil](/molmil-images/mine/7m4d) | DNA Polymerase Lambda, dCTP:At Ca2+ Ground State Ternary Complex | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2021-03-21 | Release date: | 2022-07-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.817 Å) | Cite: | Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
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7M4I
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![BU of 7m4i by Molmil](/molmil-images/mine/7m4i) | DNA Polymerase Lambda, dCTP:At Mn2+ Product State Ternary Complex, 420 min | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2021-03-21 | Release date: | 2022-07-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.005 Å) | Cite: | Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
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6RQJ
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![BU of 6rqj by Molmil](/molmil-images/mine/6rqj) | Structure of human complement C5 complexed with tick inhibitors OmCI, RaCI1 and CirpT1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5, Complement inhibitor, ... | Authors: | Reichhardt, M.P, Johnson, S, Lea, S.M. | Deposit date: | 2019-05-15 | Release date: | 2020-01-08 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | An inhibitor of complement C5 provides structural insights into activation. Proc.Natl.Acad.Sci.USA, 117, 2020
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6SA4
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![BU of 6sa4 by Molmil](/molmil-images/mine/6sa4) | SALSA / DMBT1 / GP340 SRCR domain 1 | Descriptor: | CHLORIDE ION, Deleted in malignant brain tumors 1 protein, GLYCEROL, ... | Authors: | Reichhardt, M.P, Lea, S.M, Johnson, S. | Deposit date: | 2019-07-16 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR fold. Life Sci Alliance, 3, 2020
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7S3B
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![BU of 7s3b by Molmil](/molmil-images/mine/7s3b) | |
7S3A
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![BU of 7s3a by Molmil](/molmil-images/mine/7s3a) | |
3IYV
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![BU of 3iyv by Molmil](/molmil-images/mine/3iyv) | Clathrin D6 coat as full-length Triskelions | Descriptor: | Clathrin heavy chain, Clathrin light chain A | Authors: | Johnson, G.T, Fotin, A, Cheng, Y, Sliz, P, Grigorieff, N, Harrison, S.C, Kirchhausen, T, Walz, T. | Deposit date: | 2010-06-17 | Release date: | 2010-07-21 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7.9 Å) | Cite: | Molecular model for a complete clathrin lattice from electron cryomicroscopy. Nature, 432, 2004
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2BM2
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![BU of 2bm2 by Molmil](/molmil-images/mine/2bm2) | human beta-II tryptase in complex with 4-(3-Aminomethyl-phenyl)- piperidin-1-yl-(5-phenethyl- pyridin-3-yl)-methanone | Descriptor: | 1-[3-(1-{[5-(2-PHENYLETHYL)PYRIDIN-3-YL]CARBONYL}PIPERIDIN-4-YL)PHENYL]METHANAMINE, HUMAN BETA2 TRYPTASE | Authors: | Maignan, S, Guilloteau, J.-P, Dupuy, A, Levell, J, Astles, P, Eastwood, P, Cairns, J, Houille, O, Aldous, S, Merriman, G, Whiteley, B, Pribish, J, Czekaj, M, Liang, G, Davidson, J, Harrison, T, Morley, A, Watson, S, Fenton, G, Mccarthy, C, Romano, J, Mathew, R, Engers, D, Gardyan, M, Sides, K, Kwong, J, Tsay, J, Rebello, S, Shen, L, Wang, J, Luo, Y, Giardino, O, Lim, H.-K, Smith, K, Pauls, H. | Deposit date: | 2005-03-09 | Release date: | 2005-03-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure Based Design of 4-(3-Aminomethylphenyl) Piperidinyl-1-Amides: Novel, Potent, Selective, and Orally Bioavailable Inhibitors of Bii Tryptase Bioorg.Med.Chem., 13, 2005
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7KSX
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![BU of 7ksx by Molmil](/molmil-images/mine/7ksx) | DNA Polymerase Mu, dGTP:Ct Product State Ternary Complex, 10 mM Mg2+ (30min) | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2020-11-24 | Release date: | 2021-12-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
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6NB1
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![BU of 6nb1 by Molmil](/molmil-images/mine/6nb1) | Crystal structure of Escherichia coli ClpP protease complexed with small molecule activator, ACP1-06 | Descriptor: | ATP-dependent Clp protease proteolytic subunit, GLYCEROL, N-{2-[(2-chlorophenyl)sulfanyl]ethyl}-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]sulfonyl}propanamide | Authors: | Mabanglo, M.F, Houry, W.A, Eger, B.T, Bryson, S, Pai, E.F. | Deposit date: | 2018-12-06 | Release date: | 2019-11-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores. Commun Biol, 2, 2019
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7KTA
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![BU of 7kta by Molmil](/molmil-images/mine/7kta) | DNA Polymerase Mu, 8-oxodGTP:Ct Pre-Catalytic Ground State Ternary Complex, 20 mM Ca2+ (120min) | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2020-11-24 | Release date: | 2021-12-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.844 Å) | Cite: | Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
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7KT9
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![BU of 7kt9 by Molmil](/molmil-images/mine/7kt9) | DNA Polymerase Mu, 8-oxodGTP:At Product State Ternary Complex, 50 mM Mg2+ (960min) | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2020-11-24 | Release date: | 2021-12-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.482 Å) | Cite: | Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
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7KTN
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![BU of 7ktn by Molmil](/molmil-images/mine/7ktn) | DNA Polymerase Mu, 8-oxodGTP:At Product State Ternary Complex, 10 mM Mg2+ (2160min) | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2020-11-24 | Release date: | 2021-12-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
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8ASB
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![BU of 8asb by Molmil](/molmil-images/mine/8asb) | Structure of the SFTSV L protein stalled at early elongation with the endonuclease domain in a raised conformation [EARLY-ELONGATION-ENDO] | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*CP*AP*GP*A)-3'), ... | Authors: | Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. | Deposit date: | 2022-08-18 | Release date: | 2023-01-18 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 51, 2023
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8ASD
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![BU of 8asd by Molmil](/molmil-images/mine/8asd) | Structure of the SFTSV L protein stalled at late elongation [LATE-ELONGATION] | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*GP*AP*UP*CP*UP*GP*GP*GP*CP*GP*GP*UP*CP*UP*UP*UP*GP*UP*GP*U)-3'), ... | Authors: | Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. | Deposit date: | 2022-08-19 | Release date: | 2023-01-18 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 51, 2023
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8AS7
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![BU of 8as7 by Molmil](/molmil-images/mine/8as7) | Structure of the SFTSV L protein stalled at early elongation [EARLY-ELONGATION] | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, ... | Authors: | Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. | Deposit date: | 2022-08-18 | Release date: | 2023-01-18 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 51, 2023
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