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7KT9

DNA Polymerase Mu, 8-oxodGTP:At Product State Ternary Complex, 50 mM Mg2+ (960min)

Summary for 7KT9
Entry DOI10.2210/pdb7kt9/pdb
DescriptorDNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, GLYCOLIC ACID, ... (12 entities in total)
Functional Keywordstime-lapse crystallography, oxidized nucleotide insertion, double strand break repair, replication
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight46283.65
Authors
Jamsen, J.A.,Wilson, S.H. (deposition date: 2020-11-24, release date: 2021-12-15, Last modification date: 2023-11-15)
Primary citationJamsen, J.A.,Sassa, A.,Shock, D.D.,Beard, W.A.,Wilson, S.H.
Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide.
Nat Commun, 12:2059-2059, 2021
Cited by
PubMed: 33824325
DOI: 10.1038/s41467-021-21354-6
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.482 Å)
Structure validation

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