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PDB: 63 件

5EX5
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Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with 7-deaza-ADP and inorganic phosphate
分子名称: 7-deazaadenosine-5'-diphosphate, 78 kDa glucose-regulated protein, MAGNESIUM ION, ...
著者Hughes, S.J, Antoshchenko, T, Song, J.H, Pizarro, J, Park, H.W.
登録日2015-11-23
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs.
Plos One, 11, 2016
5EVZ
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Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with ADP and inorganic phosphate
分子名称: 78 kDa glucose-regulated protein, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Hughes, S.J, Antoshchenko, T, Song, J.H, Pizarro, J, Park, H.W.
登録日2015-11-20
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs.
Plos One, 11, 2016
1HLK
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METALLO-BETA-LACTAMASE FROM BACTEROIDES FRAGILIS IN COMPLEX WITH A TRICYCLIC INHIBITOR
分子名称: 7,8-DIHYDROXY-1-METHOXY-3-METHYL-10-OXO-4,10-DIHYDRO-1H,3H-PYRANO[4,3-B]CHROMENE-9-CARBOXYLIC ACID, BETA-LACTAMASE, TYPE II, ...
著者Payne, D.J, Hueso-Rodriguez, J.A, Boyd, H, Concha, N.O, Janson, C.A, Gilpin, M, Bateson, J.H, Chever, C, Niconovich, N.L, Pearson, S, Rittenhouse, S, Tew, D, Diez, E, Perez, P, de la Fuente, J, Rees, M, Rivera-Sagredo, A.
登録日2000-12-01
公開日2001-11-30
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Identification of a series of tricyclic natural products as potent broad spectrum inhibitors of metallo-beta-lactamases
Antimicrob.Agents Chemother., 46, 2002
5UM6
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Crystal Structure of S. pombe Uba1 in a closed conformation
分子名称: 2-(decylamino)ethane-1-thiol, N-(2-{[(4-chlorophenyl)methyl]disulfanyl}ethyl)decan-1-amine, SULFATE ION, ...
著者Lv, Z, Yuan, L, Aldana-Masangkay, G, Atkison, J.H, Chen, Y, Olsen, S.K.
登録日2017-01-26
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.794 Å)
主引用文献Domain alternation and active site remodeling are conserved structural features of ubiquitin E1.
J. Biol. Chem., 292, 2017
1JXN
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Crystal Structure of the Lectin I from Ulex europaeus in complex with the methyl glycoside of alpha-L-fucose
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, CALCIUM ION, MANGANESE (II) ION, ...
著者Audette, G.F, Olson, D.J.H, Ross, A.R.S, Quail, J.W, Delbaere, L.T.J.
登録日2001-09-07
公開日2002-12-06
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Examination of the Structural Basis for O(H) Blood Group Specificity by Ulex europaeus Lectin I
Can.J.Chem., 80, 2002
1KR3
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Crystal Structure of the Metallo beta-Lactamase from Bacteroides fragilis (CfiA) in Complex with the Tricyclic Inhibitor SB-236050.
分子名称: 7,8-DIHYDROXY-1-METHOXY-3-METHYL-10-OXO-4,10-DIHYDRO-1H,3H-PYRANO[4,3-B]CHROMENE-9-CARBOXYLIC ACID, SODIUM ION, ZINC ION, ...
著者Payne, D.J, Hueso-Rodrguez, J.A, Boyd, H, Concha, N.O, Janson, C.A, Gilpin, M, Bateson, J.H, Cheever, C, Niconovich, N.L, Pearson, S, Rittenhouse, S, Tew, D, Dez, E, Prez, P, de la Fuente, J, Rees, M, Rivera-Sagredo, A.
登録日2002-01-08
公開日2003-01-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Identification of a series of tricyclic natural products as potent broad-spectrum inhibitors of metallo-beta-lactamases
ANTIMICROB.AGENTS CHEMOTHER., 46, 2002
4HAB
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Crystal structure of Plk1 Polo-box domain in complex with PL-49
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, PHOSPHATE ION, PL-49, ...
著者Lee, W.C, Song, J.H, Kim, H.Y.
登録日2012-09-26
公開日2013-04-03
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1.
Bioorg.Med.Chem., 21, 2013
4HY2
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Crystal structure of Plk1 Polo-box domain in complex with PL-42
分子名称: PL-42, Serine/threonine-protein kinase PLK1
著者Lee, W.C, Song, J.H, Kim, H.Y.
登録日2012-11-12
公開日2013-04-03
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1.
Bioorg.Med.Chem., 21, 2013
1DDK
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CRYSTAL STRUCTURE OF IMP-1 METALLO BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA
分子名称: ACETIC ACID, IMP-1 METALLO BETA-LACTAMASE, ZINC ION
著者Concha, N.O, Janson, C.A, Rowling, P, Pearson, S, Cheever, C.A, Clarke, B.P, Lewis, C, Galleni, M, Frere, J.M, Payne, D.J, Bateson, J.H, Abdel-Meguid, S.S.
登録日1999-11-10
公開日2000-11-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor.
Biochemistry, 39, 2000
1DD6
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IMP-1 METALLO BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH A MERCAPTOCARBOXYLATE INHIBITOR
分子名称: (2-MERCAPTOMETHYL-4-PHENYL-BUTYRYLIMINO)-(5-TETRAZOL-1-YLMETHYL-THIOPHEN-2-YL)-ACETIC ACID, IMP-1 METALLO BETA-LACTAMASE, SULFATE ION, ...
著者Concha, N.O, Janson, C.A, Rowling, P, Pearson, S, Cheever, C.A, Clarke, B.P, Lewis, C, Galleni, M, Frere, J.M, Payne, D.J, Bateson, J.H, Abdel-Meguid, S.S.
登録日1999-11-08
公開日2000-11-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor.
Biochemistry, 39, 2000
3U66
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Crystal structure of T6SS SciP/TssL from Escherichia Coli Enteroaggregative 042
分子名称: GLYCEROL, Putative type VI secretion protein
著者Durand, E, Aschtgen, M.S, Zoued, A, Spinelli, S, Watson, P.J.H, Cambillau, C, Cascales, E.
登録日2011-10-12
公開日2012-03-07
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structural characterization and oligomerization of the TssL protein, a component shared by bacterial type VI and type IVb secretion systems.
J.Biol.Chem., 287, 2012
1OFU
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Crystal structure of SulA:FtsZ from Pseudomonas aeruginosa
分子名称: CELL DIVISION PROTEIN FTSZ, GUANOSINE-5'-DIPHOSPHATE, HYPOTHETICAL PROTEIN PA3008
著者Cordell, S.C, Robinson, E.J.H, Lowe, J.
登録日2003-04-21
公開日2003-06-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the SOS Cell Division Inhibitor Sula and in Complex with Ftsz
Proc.Natl.Acad.Sci.USA, 100, 2003
1OFT
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Crystal structure of SulA from Pseudomonas aeruginosa
分子名称: HYPOTHETICAL PROTEIN PA3008
著者Cordell, S.C, Robinson, E.J.H, Lowe, J.
登録日2003-04-21
公開日2003-06-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of the SOS Cell Division Inhibitor Sula and in Complex with Ftsz
Proc.Natl.Acad.Sci.USA, 100, 2003
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