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PDB: 1926 results

8TDR
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BU of 8tdr by Molmil
Crystal structure of the methyltransferase domain of DNMT3A homotetramer
Descriptor: DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Lu, J.W, Song, J.K.
Deposit date:2023-07-04
Release date:2024-03-13
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations.
Nat Commun, 15, 2024
4PR6
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BU of 4pr6 by Molmil
A Second Look at the HDV Ribozyme Structure and Dynamics.
Descriptor: HDV RIBOZYME SELF-CLEAVED, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A
Authors:Kapral, G.J, Jain, S, Noeske, J, Doudna, J.A, Richardson, D.C, Richardson, J.S.
Deposit date:2014-03-05
Release date:2014-10-29
Last modified:2014-11-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:New tools provide a second look at HDV ribozyme structure, dynamics and cleavage.
Nucleic Acids Res., 42, 2014
6BRR
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BU of 6brr by Molmil
Crystal structure of DNMT3A (R836A)-DNMT3L in complex with DNA containing two CpG sites
Descriptor: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ...
Authors:Zhang, Z.M, Song, J.
Deposit date:2017-11-30
Release date:2018-01-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Structural basis for DNMT3A-mediated de novo DNA methylation.
Nature, 554, 2018
8TE3
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BU of 8te3 by Molmil
Crystal structure of the methyltransferase domain of R882C/R676K DNMT3A homotetramer
Descriptor: DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Lu, J.W, Song, J.K.
Deposit date:2023-07-05
Release date:2024-03-13
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations.
Nat Commun, 15, 2024
8TE1
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BU of 8te1 by Molmil
Crystal structure of the methyltransferase domain of R882H/R676K DNMT3A homotetramer
Descriptor: DNA (cytosine-5)-methyltransferase 3A, GLYCEROL, L(+)-TARTARIC ACID, ...
Authors:Lu, J.W, Song, J.K.
Deposit date:2023-07-05
Release date:2024-03-13
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations.
Nat Commun, 15, 2024
8TE4
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BU of 8te4 by Molmil
Crystal structure of the methyltransferase domain of R882H/N879A DNMT3A homotetramer
Descriptor: DNA (cytosine-5)-methyltransferase 3A, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Lu, J.W, Song, J.K.
Deposit date:2023-07-05
Release date:2024-03-13
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations.
Nat Commun, 15, 2024
9AAT
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BU of 9aat by Molmil
X-RAY STRUCTURE REFINEMENT AND COMPARISON OF THREE FORMS OF MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE
Authors:Mcphalen, C.A, Vincent, M.G, Jansonius, J.N.
Deposit date:1991-12-02
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase.
J.Mol.Biol., 225, 1992
2GP1
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BU of 2gp1 by Molmil
Bacteriophage HK97 Prohead II crystal structure
Descriptor: Major capsid protein
Authors:Gertsman, I, Gan, L, Johnson, J.E.
Deposit date:2006-04-15
Release date:2006-05-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (5.2 Å)
Cite:Structure and Flexibility of Bacteriophage HK97 Pre-expanded State Prohead II
To be Published
1L3L
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BU of 1l3l by Molmil
Crystal structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA
Descriptor: 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE, 5'-D(*GP*AP*TP*GP*TP*GP*CP*AP*GP*AP*TP*CP*TP*GP*CP*AP*CP*AP*TP*C)-3', Transcriptional activator protein traR
Authors:Zhang, R, Pappas, T, Brace, J.L, Miller, P.C, Oulmassov, T, Molyneaux, J.M, Anderson, J.C, Bashkin, J.K, Winans, S.C, Joachimiak, A.
Deposit date:2002-02-27
Release date:2002-07-03
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA.
Nature, 417, 2002
3HHA
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BU of 3hha by Molmil
Crystal structure of cathepsin L in complex with AZ12878478
Descriptor: ACETATE ION, Cathepsin L1, GLYCEROL, ...
Authors:Asaad, N, Bethel, P.A, Coulson, M.D, Dawson, J, Ford, S.J, Gerhardt, S, Grist, M, Hamlin, G.A, James, M.J, Jones, E.V, Karoutchi, G.I, Kenny, P.W, Morley, A.D, Oldham, K, Rankine, N, Ryan, D, Wells, S.L, Wood, L, Augustin, M, Krapp, S, Simader, H, Steinbacher, S.
Deposit date:2009-05-15
Release date:2009-06-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Dipeptidyl nitrile inhibitors of Cathepsin L.
Bioorg.Med.Chem.Lett., 19, 2009
1KWA
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BU of 1kwa by Molmil
HUMAN CASK/LIN-2 PDZ DOMAIN
Descriptor: HCASK/LIN-2 PROTEIN, SULFATE ION
Authors:Daniels, D.L, Cohen, A.R, Anderson, J.M, Brunger, A.T.
Deposit date:1998-01-16
Release date:1998-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition
Nat.Struct.Biol., 5, 1998
6BA8
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BU of 6ba8 by Molmil
YbtT - Type II thioesterase from Yersiniabactin NRPS/PKS biosynthetic pathway
Descriptor: Iron aquisition yersiniabactin synthesis enzyme, YbtT
Authors:Brett, T.J, Kober, D.L, Ohlemacher, S.I, Henderson, J.P.
Deposit date:2017-10-12
Release date:2018-10-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:YbtT is a low-specificity type II thioesterase that maintains production of the metallophore yersiniabactin in pathogenic enterobacteria.
J. Biol. Chem., 293, 2018
4ICG
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BU of 4icg by Molmil
N-terminal dimerization domain of H-NS in complex with Hha (Salmonella Typhimurium)
Descriptor: DNA-binding protein H-NS, Hemolysin expression modulating protein (Involved in environmental regulation of virulence factors)
Authors:Ali, S.S, Whitney, J.C, Stevenson, J, Robinson, H, Howell, P.L, Navarre, W.W.
Deposit date:2012-12-10
Release date:2013-03-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9217 Å)
Cite:Structural Insights into the Regulation of Foreign Genes in Salmonella by the Hha/H-NS Complex.
J.Biol.Chem., 288, 2013
3BX4
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BU of 3bx4 by Molmil
Crystal structure of the snake venom toxin aggretin
Descriptor: Aggretin alpha chain, Aggretin beta chain, GLYCEROL, ...
Authors:Hooley, E, Papagrigoriou, E, Navdaev, A, Pandey, A, Clemetson, J.M, Clemetson, K.J, Emsley, J.
Deposit date:2008-01-11
Release date:2008-08-26
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of the platelet activator aggretin reveals a novel (alphabeta)2 dimeric structure.
Biochemistry, 47, 2008
4NPD
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BU of 4npd by Molmil
High-resolution structure of C domain of staphylococcal protein A at cryogenic temperature
Descriptor: Immunoglobulin G-binding protein A, THIOCYANATE ION, ZINC ION
Authors:Deis, L.N, Pemble IV, C.W, Oas, T.G, Richardson, J.S, Richardson, D.C.
Deposit date:2013-11-21
Release date:2014-10-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:Multiscale conformational heterogeneity in staphylococcal protein a: possible determinant of functional plasticity.
Structure, 22, 2014
6I4O
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BU of 6i4o by Molmil
Dodecamer DNA containing the synthetic base pair P-Z
Descriptor: (DCZ)(DG)(DA)(DT)(DP)(DT)(DA)(DZ)(DA)(DT)(DC)(DG3)
Authors:Padroni, G, Reichenbach, L.F, Parkinson, J.A, Burley, G.A.
Deposit date:2018-11-10
Release date:2019-06-12
Last modified:2024-07-03
Method:SOLUTION NMR
Cite:Sequence-Selective Minor Groove Recognition of a DNA Duplex Containing Synthetic Genetic Components.
J.Am.Chem.Soc., 141, 2019
1M56
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BU of 1m56 by Molmil
Structure of cytochrome c oxidase from Rhodobactor sphaeroides (Wild Type)
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, COPPER (II) ION, ...
Authors:Svensson-Ek, M, Abramson, J, Larsson, G, Tornroth, S, Brezezinski, P, Iwata, S.
Deposit date:2002-07-08
Release date:2002-08-28
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The X-ray crystal structures of wild-type and EQ(I-286) mutant cytochrome c oxidases from Rhodobacter sphaeroides.
J.Mol.Biol., 321, 2002
5TLQ
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BU of 5tlq by Molmil
Model structure of the oxidized PaDsbA1 and 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine complex
Descriptor: 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine, Thiol:disulfide interchange protein DsbA
Authors:Mohanty, B, Rimmer, K.A, McMahon, R.M, Headey, S.J, Vazirani, M, Shouldice, S.R, Coincon, M, Tay, S, Morton, C.J, Simpson, J.S, Martin, J.L, Scanlon, M.S.
Deposit date:2016-10-11
Release date:2017-04-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1.
PLoS ONE, 12, 2017
8R2C
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BU of 8r2c by Molmil
Crystal structure of the Vint domain from Tetrahymena thermophila
Descriptor: DI(HYDROXYETHYL)ETHER, SULFATE ION, von willebrand factor type A (VWA) domain was originally protein
Authors:Iwai, H, Beyer, H.M, Johannson, J.E, Li, M, Wlodawer, A.
Deposit date:2023-11-03
Release date:2024-02-28
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The three-dimensional structure of the Vint domain from Tetrahymena thermophila suggests a ligand-regulated cleavage mechanism by the HINT fold.
Febs Lett., 598, 2024
7E4K
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BU of 7e4k by Molmil
WNV envelope protein
Descriptor: Core protein
Authors:Xiao, H, Qi, J, Huang, C, Song, J, Cheng, H.
Deposit date:2021-02-13
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:WNV envelope protein
To Be Published
4NPF
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BU of 4npf by Molmil
High-resolution structure of two tandem B domains of staphylococcal protein A connected by the conserved linker
Descriptor: Immunoglobulin G-binding protein A
Authors:Deis, L.N, Pemble IV, C.W, Oas, T.G, Richardson, J.S, Richardson, D.C.
Deposit date:2013-11-21
Release date:2014-10-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Multiscale conformational heterogeneity in staphylococcal protein a: possible determinant of functional plasticity.
Structure, 22, 2014
6I4N
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BU of 6i4n by Molmil
Dodecamer DNA containing the synthetic base pair P-Z in complex with a pyrrole-imidazole polyamide
Descriptor: 3-[3-[[4-[[4-[[4-[[4-[[(2~{R})-2-azaniumyl-4-[[1-methyl-4-[[1-methyl-4-[[1-methyl-4-[(1-methylimidazol-2-yl)carbonylamino]pyrrol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]butanoyl]amino]-1-methyl-imidazol-2-yl]carbonylamino]-1-methyl-pyrrol-2-yl]carbonylamino]-1-methyl-pyrrol-2-yl]carbonylamino]-1-methyl-pyrrol-2-yl]carbonylamino]propanoylamino]propyl-dimethyl-azanium, DNA (5'-D(*CP*GP*AP*TP*(DP)P*TP*AP*(DZ)P*AP*TP*CP*G)-3')
Authors:Padroni, G, Parkison, J, Burley, G.A.
Deposit date:2018-11-10
Release date:2019-06-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Sequence-Selective Minor Groove Recognition of a DNA Duplex Containing Synthetic Genetic Components.
J.Am.Chem.Soc., 141, 2019
7DXO
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BU of 7dxo by Molmil
The mutant of bifunctional thioesterase catalyzing epimerization and cyclization
Descriptor: Non-ribosomal peptide synthetase 4
Authors:Yu, J.H, Song, J, Chi, C.B, Ma, M.
Deposit date:2021-01-19
Release date:2022-01-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Functional Characterization and Crystal Structure of the Bifunctional Thioesterase Catalyzing Epimerization and Cyclization in Skyllamycin Biosynthesis
Acs Catalysis, 11, 2021
3Q6F
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BU of 3q6f by Molmil
Crystal structure of Fab of human mAb 2909 specific for quaternary neutralizing epitope of HIV-1 gp120
Descriptor: DI(HYDROXYETHYL)ETHER, Heavy chain of Fab of human mAb 2909, Light chain of Fab of human mAb 2909
Authors:Spurrier, B, Sampson, J, Totrov, M, Li, H, O'Neal, T, William, C, Robinson, J, Gorny, M.K, Zolla-Pazner, S, Kong, X.P.
Deposit date:2010-12-31
Release date:2011-05-25
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (3.192 Å)
Cite:Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120.
Structure, 19, 2011
7KW7
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BU of 7kw7 by Molmil
Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glucocorticoid receptor, Heat shock 70 kDa protein 1A, ...
Authors:Wang, R.Y, Noddings, C.M, Kirschke, E, Myasnikov, A, Johnson, J.L, Agard, D.A.
Deposit date:2020-11-30
Release date:2021-12-08
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism.
Nature, 601, 2022

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