7DXO

The mutant of bifunctional thioesterase catalyzing epimerization and cyclization

Summary for 7DXO

• Entry DOI: 10.2210/pdb7dxo/pdb
• Descriptor: Non-ribosomal peptide synthetase 4 (2 entities in total)
• Functional Keywords: hydrolase fold, thioesterase, epimerization, cyclization, biosynthetic protein
• Biological source: Streptomyces abietis
• Total number of polymer chains: 3
• Total formula weight: 90614.93

Authors

Yu, J.H.,Song, J.,Chi, C.B.,Ma, M. (deposition date: 2021-01-19, release date: 2022-01-26, Last modification date: 2023-11-29)

• Primary citation: Yu, J.,Juan, S.,Chi, C.,Liu, T.,Geng, T.,Cai, Z.,Dong, W.,Shi, C.,Ma, X.,Zhang, Z.,Ma, X.,Xing, B.,Jin, H.,Zhang, L.,Dong, S.,Yang, D.,Ma, M.; Functional Characterization and Crystal Structure of the Bifunctional Thioesterase Catalyzing Epimerization and Cyclization in Skyllamycin Biosynthesis; Acs Catalysis, 11:11733-11741, 2021; DOI: 10.1021/acscatal.1c03064

Experimental method

X-RAY DIFFRACTION (2.4 Å)