3B8J
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1YM9
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![BU of 1ym9 by Molmil](/molmil-images/mine/1ym9) | Crystal structure of the CDC25B phosphatase catalytic domain with the active site cysteine in the sulfinic form | Descriptor: | CHLORIDE ION, M-phase inducer phosphatase 2 | Authors: | Buhrman, G.K, Parker, B, Sohn, J, Rudolph, J, Mattos, C. | Deposit date: | 2005-01-20 | Release date: | 2005-04-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Mechanism of Oxidative Regulation of the Phosphatase Cdc25B via an Intramolecular Disulfide Bond Biochemistry, 44, 2005
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1YML
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![BU of 1yml by Molmil](/molmil-images/mine/1yml) | Crystal Structure of the CDC25B phosphatase catalytic domain with the active site cysteine in the sulfenic form | Descriptor: | CHLORIDE ION, M-phase inducer phosphatase 2 | Authors: | Buhrman, G.K, Parker, B, Sohn, J, Rudolph, J, Mattos, C. | Deposit date: | 2005-01-21 | Release date: | 2005-04-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Mechanism of Oxidative Regulation of the Phosphatase Cdc25B via an Intramolecular Disulfide Bond Biochemistry, 44, 2005
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1YMD
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![BU of 1ymd by Molmil](/molmil-images/mine/1ymd) | Crystal Structure of the CDC25B phosphatase catalytic domain with the active site cysteine in the sulfonic form | Descriptor: | CHLORIDE ION, M-phase inducer phosphatase 2 | Authors: | Buhrman, G.K, Parker, B, Sohn, J, Rudolph, J, Mattos, C. | Deposit date: | 2005-01-20 | Release date: | 2005-04-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Mechanism of Oxidative Regulation of the Phosphatase Cdc25B via an Intramolecular Disulfide Bond Biochemistry, 44, 2005
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1YMK
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![BU of 1ymk by Molmil](/molmil-images/mine/1ymk) | Crystal Structure of the CDC25B phosphatase catalytic domain in the apo form | Descriptor: | CHLORIDE ION, M-phase inducer phosphatase 2 | Authors: | Buhrman, G.K, Parker, B, Sohn, J, Rudolph, J, Mattos, C. | Deposit date: | 2005-01-21 | Release date: | 2005-04-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Mechanism of Oxidative Regulation of the Phosphatase Cdc25B via an Intramolecular Disulfide Bond Biochemistry, 44, 2005
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1YS0
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![BU of 1ys0 by Molmil](/molmil-images/mine/1ys0) | Crystal Structure of the CDC25B phosphatase catalytic domain with the active site cysteine in the disulfide form | Descriptor: | CHLORIDE ION, M-phase inducer phosphatase 2 | Authors: | Buhrman, G.K, Parker, B, Sohn, J, Rudolph, J, Mattos, C. | Deposit date: | 2005-02-05 | Release date: | 2005-04-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Mechanism of Oxidative Regulation of the Phosphatase Cdc25B via an Intramolecular Disulfide Bond Biochemistry, 44, 2005
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7UXW
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![BU of 7uxw by Molmil](/molmil-images/mine/7uxw) | Structure of ATP and GTP bind to Cyclic GMP AMP synthase (cGAS) through Mg coordination | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Wu, S, Gabelli, S.B, Sohn, J. | Deposit date: | 2022-05-06 | Release date: | 2023-05-10 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS Nat Commun, 15, 2024
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7UYQ
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![BU of 7uyq by Molmil](/molmil-images/mine/7uyq) | Structure of GTP binds to Cyclic GMP AMP synthase (cGAS) through Mg coordination | Descriptor: | Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wu, S, Gabelli, S.B, Sohn, J. | Deposit date: | 2022-05-07 | Release date: | 2023-05-10 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS Nat Commun, 15, 2024
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7UYZ
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![BU of 7uyz by Molmil](/molmil-images/mine/7uyz) | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG | Descriptor: | Cyclic GMP-AMP synthase, GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Wu, S, Gabelli, S.B, Sohn, J. | Deposit date: | 2022-05-07 | Release date: | 2023-05-10 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS Nat Commun, 15, 2024
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7UZR
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![BU of 7uzr by Molmil](/molmil-images/mine/7uzr) | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG | Descriptor: | Cyclic GMP-AMP synthase, MANGANESE (II) ION, Palindromic DNA18, ... | Authors: | Wu, S, Gabelli, S.B, Sohn, J. | Deposit date: | 2022-05-09 | Release date: | 2023-05-10 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS Nat Commun, 15, 2024
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8SJ2
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8SJ8
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![BU of 8sj8 by Molmil](/molmil-images/mine/8sj8) | Structure of binary complex of human cGAS and bound ppp(2'-5')GpG | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION, [[(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | Authors: | Wu, S, Sohn, J. | Deposit date: | 2023-04-17 | Release date: | 2024-04-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
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8SJ0
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8SI0
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8SHU
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![BU of 8shu by Molmil](/molmil-images/mine/8shu) | Structure of mouse cGAS | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION | Authors: | Wu, S, Sohn, J. | Deposit date: | 2023-04-14 | Release date: | 2024-04-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
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8SHK
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8SJ1
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8SHY
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8SHZ
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![BU of 8shz by Molmil](/molmil-images/mine/8shz) | Structure of human cGAS | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION | Authors: | Wu, S, Sohn, J. | Deposit date: | 2023-04-14 | Release date: | 2024-04-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
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8SKT
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8G10
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8G1J
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8G23
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8G2Q
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8G2P
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![BU of 8g2p by Molmil](/molmil-images/mine/8g2p) | |