4IDC
| Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and HDMF | Descriptor: | (2R)-4-hydroxy-2,5-dimethylfuran-3(2H)-one, 1,2-ETHANEDIOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Schiefner, A, Skerra, A. | Deposit date: | 2012-12-12 | Release date: | 2013-04-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone J.Biol.Chem., 288, 2013
|
|
4IDA
| |
5N5V
| |
5N5U
| |
3LY8
| |
3LRH
| |
3LYA
| |
3LRG
| Structure of anti-huntingtin VL domain | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IMIDAZOLE, anti-huntingtin VL domain | Authors: | Schiefner, A, Chatwell, L, Skerra, A. | Deposit date: | 2010-02-11 | Release date: | 2011-02-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | A Disulfide-Free Single-Domain V(L) Intrabody with Blocking Activity towards Huntingtin Reveals a Novel Mode of Epitope Recognition. J.Mol.Biol., 414, 2011
|
|
3LY9
| |
3LY7
| |
3MBT
| Structure of monomeric Blc from E. coli | Descriptor: | Outer membrane lipoprotein blc | Authors: | Schiefner, A, Skerra, A. | Deposit date: | 2010-03-26 | Release date: | 2010-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and biochemical analyses reveal a monomeric state of the bacterial lipocalin Blc. Acta Crystallogr.,Sect.D, 66, 2010
|
|
4I5D
| Crystal structure of Ralstonia sp. alcohol dehydrogenase in its apo form | Descriptor: | Alclohol dehydrogenase/short-chain dehydrogenase, SULFATE ION | Authors: | Jarasch, A, Lerchner, A, Meining, W, Schiefner, A, Skerra, A. | Deposit date: | 2012-11-28 | Release date: | 2013-06-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. Alcohol dehydrogenase toward NADH cosubstrate specificity. Biotechnol.Bioeng., 110, 2013
|
|
4I5E
| Crystal structure of Ralstonia sp. alcohol dehydrogenase in complex with NADP+ | Descriptor: | Alclohol dehydrogenase/short-chain dehydrogenase, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Jarasch, A, Lerchner, A, Meining, W, Schiefner, A, Skerra, A. | Deposit date: | 2012-11-28 | Release date: | 2013-06-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. Alcohol dehydrogenase toward NADH cosubstrate specificity. Biotechnol.Bioeng., 110, 2013
|
|
4I5F
| Crystal structure of Ralstonia sp. alcohol dehydrogenase mutant N15G, G37D, R38V, R39S | Descriptor: | Alclohol dehydrogenase/short-chain dehydrogenase | Authors: | Jarasch, A, Lerchner, A, Meining, W, Schiefner, A, Skerra, A. | Deposit date: | 2012-11-28 | Release date: | 2013-06-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. Alcohol dehydrogenase toward NADH cosubstrate specificity. Biotechnol.Bioeng., 110, 2013
|
|
4H8J
| Structure of GluA2-LBD in complex with MES | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Glutamate receptor 2, ... | Authors: | Reiter, A, Skerra, A, Trauner, D, Schiefner, A. | Deposit date: | 2012-09-22 | Release date: | 2013-09-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of an artificial photoreceptor To be Published
|
|
4H8I
| Structure of GluK2-LBD in complex with GluAzo | Descriptor: | (4R)-4-[(2E)-3-{4-[(E)-phenyldiazenyl]phenyl}prop-2-en-1-yl]-L-glutamic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | Authors: | Reiter, A, Skerra, A, Trauner, D, Schiefner, A. | Deposit date: | 2012-09-22 | Release date: | 2013-09-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A photoswitchable neurotransmitter analogue bound to its receptor. Biochemistry, 52, 2013
|
|
4GRX
| Structure of an omega-aminotransferase from Paracoccus denitrificans | Descriptor: | Aminotransferase, DELTA-AMINO VALERIC ACID, SODIUM ION | Authors: | Rausch, C, Lerchner, A, Schiefner, A, Skerra, A. | Deposit date: | 2012-08-27 | Release date: | 2012-12-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the omega-aminotransferase from Paracoccus denitrificans and its phylogenetic relationship with other class III aminotransferases that have biotechnological potential. Proteins, 81, 2013
|
|
3KQ0
| Crystal structure of human alpha1-acid glycoprotein | Descriptor: | (2R)-2,3-dihydroxypropyl acetate, Alpha-1-acid glycoprotein 1, CHLORIDE ION | Authors: | Schiefner, A, Schonfeld, D.L, Ravelli, R.B.G, Mueller, U, Skerra, A. | Deposit date: | 2009-11-17 | Release date: | 2010-02-02 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The 1.8-A crystal structure of alpha1-acid glycoprotein (Orosomucoid) solved by UV RIP reveals the broad drug-binding activity of this human plasma lipocalin. J.Mol.Biol., 384, 2008
|
|
4GH7
| |
4HH8
| Crystal structure of bovine butyrophilin | Descriptor: | Butyrophilin subfamily 1 member A1 | Authors: | Eichinger, A, Skerra, A. | Deposit date: | 2012-10-09 | Release date: | 2013-11-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The extracellular region of bovine butyrophilin exhibits high structural similarity to human myelin oligodendrocyte glycoprotein To be Published
|
|
1T0V
| NMR Solution Structure of the Engineered Lipocalin FluA(R95K) Northeast Structural Genomics Target OR17 | Descriptor: | BILIN-BINDING PROTEIN | Authors: | Mills, J.L, Liu, G, Skerra, A, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-04-13 | Release date: | 2005-06-14 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | NMR structure and dynamics of the engineered fluorescein-binding lipocalin FluA reveal rigidification of beta-barrel and variable loops upon enthalpy-driven ligand binding. Biochemistry, 48, 2009
|
|
4IAW
| Engineered human lipocalin 2 (C26) in complex with Y-DTPA | Descriptor: | N-{(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl}-N-{(2R)-2-[bis(carboxymethyl)amino]-3-[4-({[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamothioyl}amino)phenyl]propyl}glycine, Neutrophil gelatinase-associated lipocalin, YTTRIUM (III) ION | Authors: | Eichinger, A, Skerra, A. | Deposit date: | 2012-12-07 | Release date: | 2013-06-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure-guided engineering of Anticalins with improved binding behavior and biochemical characteristics for application in radio-immuno imaging and/or therapy J.Struct.Biol., 185, 2014
|
|
4IAX
| Engineered human lipocalin 2 (CL31) in complex with Y-DTPA | Descriptor: | N-{(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl}-N-{(2R)-2-[bis(carboxymethyl)amino]-3-[4-({[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamothioyl}amino)phenyl]propyl}glycine, Neutrophil gelatinase-associated lipocalin, YTTRIUM (III) ION | Authors: | Eichinger, A, Skerra, A. | Deposit date: | 2012-12-07 | Release date: | 2013-06-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-guided engineering of Anticalins with improved binding behavior and biochemical characteristics for application in radio-immuno imaging and/or therapy J.Struct.Biol., 185, 2014
|
|