1VB6
| Crystal Structure of the heme PAS sensor domain of Ec DOS (oxygen-bound form) | 分子名称: | Heme pas sensor protein, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Kurokawa, H, Watanabe, M, Sagami, I, Mikami, B, Shimizu, T. | 登録日 | 2004-02-24 | 公開日 | 2005-04-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Structure of oxygen-bound form of a Heme PAS domain of Ec DOS To be Published
|
|
5Y3M
| |
5Y3L
| Crystal structure of horse TLR9 in complex with two DNAs (CpG DNA and CCGCAC DNA) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (5'-D(*AP*GP*GP*CP*GP*TP*TP*TP*TP*T)-3'), ... | 著者 | Ohto, U, Shimizu, T. | 登録日 | 2017-07-29 | 公開日 | 2018-04-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation Immunity, 48, 2018
|
|
5WRD
| Crystal structure of LC3B in complex with FYCO1 LIR | 分子名称: | GLYCEROL, Microtubule-associated proteins 1A/1B light chain 3B, Peptide from FYVE and coiled-coil domain-containing protein 1 | 著者 | Sakurai, S, Ohto, U, Shimizu, T. | 登録日 | 2016-12-01 | 公開日 | 2017-03-29 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The crystal structure of mouse LC3B in complex with the FYCO1 LIR reveals the importance of the flanking region of the LIR motif Acta Crystallogr F Struct Biol Commun, 73, 2017
|
|
5Y3J
| Crystal structure of horse TLR9 in complex with two DNAs (CpG DNA and TCGCAC DNA) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (5'-D(*AP*GP*GP*CP*GP*TP*TP*TP*TP*T)-3'), ... | 著者 | Ohto, U, Ishida, H, Shimizu, T. | 登録日 | 2017-07-29 | 公開日 | 2018-04-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation Immunity, 48, 2018
|
|
5Y3K
| Crystal structure of horse TLR9 in complex with two DNAs (CpG DNA and GCGCAC DNA) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (5'-D(*AP*GP*GP*CP*GP*TP*TP*TP*TP*T)-3'), ... | 著者 | Ohto, U, Shimizu, T. | 登録日 | 2017-07-29 | 公開日 | 2018-04-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation Immunity, 48, 2018
|
|
7VTQ
| Cryo-EM structure of mouse NLRP3 (full-length) dodecamer | 分子名称: | 1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea, ADENOSINE-5'-DIPHOSPHATE, NACHT, ... | 著者 | Ohto, U, Shimizu, T. | 登録日 | 2021-10-30 | 公開日 | 2022-03-09 | 最終更新日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | 主引用文献 | Structural basis for the oligomerization-mediated regulation of NLRP3 inflammasome activation. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7VTP
| Cryo-EM structure of PYD-deleted human NLRP3 hexamer | 分子名称: | 1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea, ADENOSINE-5'-DIPHOSPHATE, NACHT, ... | 著者 | Ohto, U, Shimizu, T. | 登録日 | 2021-10-30 | 公開日 | 2022-03-09 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Structural basis for the oligomerization-mediated regulation of NLRP3 inflammasome activation. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7WBU
| Cryo-EM structure of bovine NLRP9 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, NACHT, LRR and PYD domains-containing protein 9 | 著者 | Kamitsukasa, Y, Shimizu, T, Ohto, U. | 登録日 | 2021-12-17 | 公開日 | 2022-04-06 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | The structure of NLRP9 reveals a unique C-terminal region with putative regulatory function. Febs Lett., 596, 2022
|
|
7WBT
| Crystal structure of bovine NLRP9 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, NACHT, LRR and PYD domains-containing protein 9 | 著者 | Kamitsukasa, Y, Shimizu, T, Ohto, U. | 登録日 | 2021-12-17 | 公開日 | 2022-04-06 | 最終更新日 | 2022-04-27 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | The structure of NLRP9 reveals a unique C-terminal region with putative regulatory function. Febs Lett., 596, 2022
|
|
2DM6
| Crystal structure of anti-configuration of indomethacin and leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complex | 分子名称: | INDOMETHACIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent leukotriene B4 12-hydroxydehydrogenase, ... | 著者 | Hori, T, Ishijima, J, Yokomizo, T, Ago, H, Shimizu, T, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-04-20 | 公開日 | 2006-11-28 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of anti-configuration of indomethacin and leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complex reveals the structural basis of broad spectrum indomethacin efficacy J.Biochem.(Tokyo), 140, 2006
|
|
5XDR
| Crystal structure of human DEAH-box RNA helicase DHX15 in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15, ... | 著者 | Murakami, K, Nakano, K, Shimizu, T, Ohto, U. | 登録日 | 2017-03-29 | 公開日 | 2017-06-21 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The crystal structure of human DEAH-box RNA helicase 15 reveals a domain organization of the mammalian DEAH/RHA family Acta Crystallogr F Struct Biol Commun, 73, 2017
|
|
5YAQ
| Crystal structure of scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity complexed with scyllo-inosose | 分子名称: | (2R,3S,4s,5R,6S)-2,3,4,5,6-pentahydroxycyclohexanone, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity | 著者 | Fukano, K, Shimizu, T, Sasaki, Y, Nakamura, A, Yajima, S. | 登録日 | 2017-09-01 | 公開日 | 2018-05-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural basis of L-glucose oxidation by scyllo-inositol dehydrogenase: Implications for a novel enzyme subfamily classification PLoS ONE, 13, 2018
|
|
5YAB
| Crystal structure of scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity | 分子名称: | ACETATE ION, Scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity | 著者 | Fukano, K, Shimizu, T, Sasaki, Y, Nakamura, A, Yajima, S. | 登録日 | 2017-08-31 | 公開日 | 2018-05-23 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural basis of L-glucose oxidation by scyllo-inositol dehydrogenase: Implications for a novel enzyme subfamily classification PLoS ONE, 13, 2018
|
|
5YAP
| Crystal structure of scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity complexed with L-glucono-1,5-lactone | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-glucono-1,5-lactone, Scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity | 著者 | Fukano, K, Shimizu, T, Sasaki, Y, Nakamura, A, Yajima, S. | 登録日 | 2017-09-01 | 公開日 | 2018-05-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis of L-glucose oxidation by scyllo-inositol dehydrogenase: Implications for a novel enzyme subfamily classification PLoS ONE, 13, 2018
|
|
5Y7Y
| Crystal structure of AhRR/ARNT complex | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, Aryl hydrocarbon receptor repressor, GLYCEROL | 著者 | Sakurai, S, Shimizu, T, Ohto, U. | 登録日 | 2017-08-18 | 公開日 | 2017-09-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The crystal structure of the AhRR-ARNT heterodimer reveals the structural basis of the repression of AhR-mediated transcription. J. Biol. Chem., 292, 2017
|
|
5YA8
| Crystal structure of scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity complexed with myo-inositol | 分子名称: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity | 著者 | Fukano, K, Shimizu, T, Sasaki, Y, Nakamura, A, Yajima, S. | 登録日 | 2017-08-31 | 公開日 | 2018-05-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis of L-glucose oxidation by scyllo-inositol dehydrogenase: Implications for a novel enzyme subfamily classification PLoS ONE, 13, 2018
|
|
5WYX
| Crystal structure of human TLR8 in complex with CU-CPT8m | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide, ... | 著者 | Tanji, H, Ohto, U, Shimizu, T. | 登録日 | 2017-01-16 | 公開日 | 2017-12-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Small-molecule inhibition of TLR8 through stabilization of its resting state Nat. Chem. Biol., 14, 2018
|
|
5Z15
| Crystal structure of human TLR8 in complex with CU-CPT9c | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(7-chloranylquinolin-4-yl)-2-methyl-phenol, ... | 著者 | Tanji, H, Ohto, U, Shimizu, T. | 登録日 | 2017-12-25 | 公開日 | 2018-07-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Inhibition of Toll-like Receptor 8 by Specifically Targeting a Unique Allosteric Site and Locking Its Resting State To Be Published
|
|
5WYZ
| Crystal structure of human TLR8 in complex with CU-CPT9b | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(3-methyl-4-oxidanyl-phenyl)quinolin-7-ol, ... | 著者 | Tanji, H, Ohto, U, Shimizu, T. | 登録日 | 2017-01-16 | 公開日 | 2017-12-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Small-molecule inhibition of TLR8 through stabilization of its resting state Nat. Chem. Biol., 14, 2018
|
|
5Z14
| Crystal structure of human TLR8 in complex with CU-CPT9a | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(7-methoxyquinolin-4-yl)-2-methyl-phenol, ... | 著者 | Tanji, H, Ohto, U, Shimizu, T. | 登録日 | 2017-12-25 | 公開日 | 2018-07-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Inhibition of Toll-like Receptor 8 by Specifically Targeting a Unique Allosteric Site and Locking Its Resting State To Be Published
|
|
2COV
| Crystal structure of CBM31 from beta-1,3-xylanase | 分子名称: | beta-1,3-xylanase | 著者 | Hashimoto, H, Tamai, Y, Okazaki, F, Tamaru, Y, Shimizu, T, Araki, T, Sato, M. | 登録日 | 2005-05-18 | 公開日 | 2005-09-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | The first crystal structure of a family 31 carbohydrate-binding module with affinity to beta-1,3-xylan Febs Lett., 579, 2005
|
|
2DEX
| Crystal structure of human peptidylarginine deiminase 4 in complex with histone H3 N-terminal peptide including Arg17 | 分子名称: | 10-mer peptide from histone H3, CALCIUM ION, Protein-arginine deiminase type IV, ... | 著者 | Arita, K, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M. | 登録日 | 2006-02-18 | 公開日 | 2006-04-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4 Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2DEW
| Crystal structure of human peptidylarginine deiminase 4 in complex with histone H3 N-terminal tail including Arg8 | 分子名称: | 10-mer peptide from histone H3, CALCIUM ION, Protein-arginine deiminase type IV, ... | 著者 | Arita, K, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M. | 登録日 | 2006-02-18 | 公開日 | 2006-04-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4 Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2E1N
| |