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PDB: 311 件

1A0A
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PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4/DNA COMPLEX
分子名称: DNA (5'-D(*CP*TP*AP*GP*TP*CP*CP*CP*AP*CP*GP*TP*GP*TP*GP*AP*G )-3'), DNA (5'-D(*CP*TP*CP*AP*CP*AP*CP*GP*TP*GP*GP*GP*AP*CP*TP*AP*G )-3'), PROTEIN (PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4)
著者Shimizu, T, Toumoto, A, Ihara, K, Shimizu, M, Kyogoku, Y, Ogawa, N, Oshima, Y, Hakoshima, T.
登録日1997-11-27
公開日1998-03-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition.
EMBO J., 16, 1997
2MLQ
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Human CCR2 Membrane-Proximal C-Terminal Region (PRO-C) in a frount bound form
分子名称: MCP-1 receptor
著者Esaki, K, Yoshinaga, S, Tsuji, T, Toda, E, Terashima, Y, Saitoh, T, Kohda, D, Kohno, T, Osawa, M, Ueda, T, Shimada, I, Matsushima, K, Terasawa, H.
登録日2014-03-04
公開日2014-10-08
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNT.
Febs J., 281, 2014
3WZU
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THE STRUCTURE OF MAP2K7 IN COMPLEX WITH 5Z-7-oxozeaenol
分子名称: (3S,5Z,8S,9S,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione, Dual specificity mitogen-activated protein kinase kinase 7
著者Sogabe, Y, Hashimoto, Y, Matsumoto, T, Kinoshita, T.
登録日2014-10-07
公開日2015-01-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献5Z-7-Oxozeaenol covalently binds to MAP2K7 at Cys218 in an unprecedented manner.
Bioorg.Med.Chem.Lett., 25, 2015
3WZQ
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Crystal structure of the core streptavidin mutant V212 (Y22S/N23D/S27D/S45N/Y83S/R84K/E101D/R103K/E116N) complexed with iminobiotin long tail (IMNtail) at 1.7 A resolution
分子名称: 6-({5-[(2E,3aS,4S,6aR)-2-iminohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)hexanoic acid, HEXAETHYLENE GLYCOL, Streptavidin
著者Kawato, T, Mizohata, E, Shimizu, Y, Meshizuka, T, Yamamoto, T, Takasu, N, Matsuoka, M, Matsumura, H, Tsumoto, K, Kodama, T, Kanai, M, Doi, H, Inoue, T, Sugiyama, A.
登録日2014-10-01
公開日2015-02-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-based design of a streptavidin mutant specific for an artificial biotin analogue.
J.Biochem., 157, 2015
3WZP
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Crystal structure of the core streptavidin mutant V21 (Y22S/N23D/S27D/Y83S/R84K/E101D/R103K/E116N) complexed with iminobiotin long tail (IMNtail) at 1.2 A resolution
分子名称: 6-({5-[(2E,3aS,4S,6aR)-2-iminohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)hexanoic acid, GLYCEROL, Streptavidin
著者Kawato, T, Mizohata, E, Shimizu, Y, Meshizuka, T, Yamamoto, T, Takasu, N, Matsuoka, M, Matsumura, H, Tsumoto, K, Kodama, T, Kanai, M, Doi, H, Inoue, T, Sugiyama, A.
登録日2014-10-01
公開日2015-02-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure-based design of a streptavidin mutant specific for an artificial biotin analogue.
J.Biochem., 157, 2015
3X00
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Crystal structure of the core streptavidin mutant V212 (Y22S/N23D/S27D/S45N/Y83S/R84K/E101D/R103K/E116N) complexed with bis iminobiotin long tail (Bis-IMNtail) at 1.3 A resolution
分子名称: 6-({5-[(2E,3aS,4S,6aR)-2-iminohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)hexanoic acid, ETHANE-1,2-DIAMINE, Streptavidin
著者Kawato, T, Mizohata, E, Shimizu, Y, Meshizuka, T, Yamamoto, T, Takasu, N, Matsuoka, M, Matsumura, H, Kodama, T, Kanai, M, Doi, H, Inoue, T, Sugiyama, A.
登録日2014-10-09
公開日2015-01-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure-based design and synthesis of a bivalent iminobiotin analog showing strong affinity toward a low immunogenic streptavidin mutant.
Biosci.Biotechnol.Biochem., 79, 2015
7Q5V
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HIF PROLYL HYDROXYLASE 2 (PHD2/EGLN1) IN COMPLEX WITH N-OXALYLGLYCINE (NOG) AND HIF-2 ALPHA CODD (523-542)
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Egl nine homolog 1, ...
著者Figg Jr, W.D, McDonough, M.A, Chowdhury, R, Nakashima, Y, Schofield, C.J.
登録日2021-11-04
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Structural basis for binding of the renal carcinoma target hypoxia-inducible factor 2 alpha to prolyl hydroxylase domain 2.
Proteins, 91, 2023
5ZX8
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Crystal structure of peptidyl-tRNA hydrolase from Thermus thermophilus
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CITRATE ANION, Peptidyl-tRNA hydrolase
著者Matsumoto, A, Uehara, U, Shimizu, Y, Ueda, T, Uchiumi, T, Ito, K.
登録日2018-05-18
公開日2018-09-26
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献High-resolution crystal structure of peptidyl-tRNA hydrolase from Thermus thermophilus.
Proteins, 87, 2019
3WZN
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Crystal structure of the core streptavidin mutant V21 (Y22S/N23D/S27D/Y83S/R84K/E101D/R103K/E116N) complexed with biotin at 1.3 A resolution
分子名称: BIOTIN, SULFATE ION, Streptavidin
著者Kawato, T, Mizohata, E, Shimizu, Y, Meshizuka, T, Yamamoto, T, Takasu, N, Matsuoka, M, Matsumura, H, Tsumoto, K, Kodama, T, Kanai, M, Doi, H, Inoue, T, Sugiyama, A.
登録日2014-10-01
公開日2015-02-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure-based design of a streptavidin mutant specific for an artificial biotin analogue.
J.Biochem., 157, 2015
7BWI
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Solution structure of recombinant APETx1
分子名称: Kappa-actitoxin-Ael2a
著者Matsumura, K, Kobayashi, N, Kurita, J, Nishimura, Y, Yokogawa, M, Imai, S, Shimada, I, Osawa, M.
登録日2020-04-14
公開日2020-12-23
最終更新日2024-10-16
実験手法SOLUTION NMR
主引用文献Mechanism of hERG inhibition by gating-modifier toxin, APETx1, deduced by functional characterization.
Bmc Mol Cell Biol, 22, 2021
3WZO
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Crystal structure of the core streptavidin mutant V21 (Y22S/N23D/S27D/Y83S/R84K/E101D/R103K/E116N) complexed with biotin long tail (BTNtail) at 1.5 A resolution
分子名称: 6-({5-[(3aS,4S,5S,6aR)-5-oxido-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)hexanoic acid, CADMIUM ION, GLYCEROL, ...
著者Kawato, T, Mizohata, E, Shimizu, Y, Meshizuka, T, Yamamoto, T, Takasu, N, Matsuoka, M, Matsumura, H, Tsumoto, K, Kodama, T, Kanai, M, Doi, H, Inoue, T, Sugiyama, A.
登録日2014-10-01
公開日2015-02-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-based design of a streptavidin mutant specific for an artificial biotin analogue.
J.Biochem., 157, 2015
7Q5X
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HIF PROLYL HYDROXYLASE 2 (PHD2/EGLN1) IN COMPLEX WITH 2-OXOGLUTARATE (2OG) AND HIF-2 ALPHA CODD (523-542)
分子名称: 2-OXOGLUTARIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Figg Jr, W.D, McDonough, M.A, Chowdhury, R, Nakashima, Y, Schofield, C.J.
登録日2021-11-04
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Structural basis for binding of the renal carcinoma target hypoxia-inducible factor 2 alpha to prolyl hydroxylase domain 2.
Proteins, 91, 2023
8YFY
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CRYSTAL STRUCTURE OF THE EST1 H274D MUTANT AT PH 4.2
分子名称: Carboxylesterase, octyl beta-D-glucopyranoside
著者Unno, H, Oshima, Y, Nishino, T, Nakayama, T, Kusunoki, M.
登録日2024-02-26
公開日2024-07-10
最終更新日2024-08-28
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Lowering pH optimum of activity of SshEstI, a slightly alkaliphilic archaeal esterase of the hormone-sensitive lipase family.
J.Biosci.Bioeng., 138, 2024
8YFZ
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CRYSTAL STRUCTURE OF THE EST1 H274E MUTANT AT PH 4.2
分子名称: Carboxylesterase, octyl beta-D-glucopyranoside
著者Unno, H, Oshima, Y, Nishino, T, Nakayama, T, Kusunoki, M.
登録日2024-02-26
公開日2024-07-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Lowering pH optimum of activity of SshEstI, a slightly alkaliphilic archaeal esterase of the hormone-sensitive lipase family.
J.Biosci.Bioeng., 2024
1BA5
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DNA-BINDING DOMAIN OF HUMAN TELOMERIC PROTEIN, HTRF1, NMR, 18 STRUCTURES
分子名称: HTRF1
著者Nishikawa, T, Nagadoi, A, Yoshimura, S, Aimoto, S, Nishimura, Y.
登録日1998-04-22
公開日1999-04-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA-binding domain of human telomeric protein, hTRF1.
Structure, 6, 1998
1UBB
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Crystal structure of rat HO-1 in complex with ferrous heme
分子名称: Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
著者Sugishima, M, Sakamoto, H, Higashimoto, Y, Noguchi, M, Fukuyama, K.
登録日2003-04-03
公開日2003-09-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Ferrous and CO-, CN(-)-, and NO-Bound Forms of Rat Heme Oxygenase-1 (HO-1) in Complex with Heme: Structural Implications for Discrimination between CO and O(2) in HO-1.
Biochemistry, 42, 2003
3WKT
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Complex structure of an open form of NADPH-cytochrome P450 reductase and heme oxygenase-1
分子名称: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, Heme oxygenase 1, ...
著者Sugishima, M, Sato, H, Higashimoto, Y, Harada, J, Wada, K, Fukuyama, K, Noguchi, M.
登録日2013-10-31
公開日2014-01-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Structural basis for the electron transfer from an open form of NADPH-cytochrome P450 oxidoreductase to heme oxygenase.
Proc.Natl.Acad.Sci.USA, 111, 2014
3J3Z
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Structure of MA28-7 neutralizing antibody Fab fragment from electron cryo-microscopy of enterovirus 71 complexed with a Fab fragment
分子名称: MA28-7 neutralizing antibody heavy chain, MA28-7 neutralizing antibody light chain
著者Lee, H, Cifuente, J.O, Ashley, R.E, Conway, J.F, Makhov, A.M, Tano, Y, Shimizu, H, Nishimura, Y, Hafenstein, S.
登録日2013-05-21
公開日2013-08-28
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (23.4 Å)
主引用文献A strain-specific epitope of enterovirus 71 identified by cryo-electron microscopy of the complex with fab from neutralizing antibody.
J.Virol., 87, 2013
2RSO
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Solution structure of the chromodomain of Swi6
分子名称: Chromatin-associated protein swi6
著者Shimojo, H, Nishimura, Y.
登録日2012-04-18
公開日2012-08-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Intrinsic nucleic Acid-binding activity of chp1 chromodomain is required for heterochromatic gene silencing
Mol.Cell, 47, 2012
2RSN
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Solution structure of the chromodomain of Chp1 in complex with H3K9me3 peptide
分子名称: Chromo domain-containing protein 1, peptide from Histone H3
著者Shimojo, H, Nishimura, Y.
登録日2012-04-18
公開日2012-08-29
実験手法SOLUTION NMR
主引用文献Intrinsic nucleic Acid-binding activity of chp1 chromodomain is required for heterochromatic gene silencing
Mol.Cell, 47, 2012
8Z8R
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norbelladine 4'-O-methyltransferase S52T complexed with Mg and SAH
分子名称: GLYCEROL, MAGNESIUM ION, Norbelladine 4'-O-methyltransferase, ...
著者Saw, Y.Y.H, Nakashima, Y, Morita, H.
登録日2024-04-22
公開日2024-08-07
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases
Acs Catalysis, 2024
8ZFW
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norbelladine 4'-O-methyltransferase S52T Y186F complexed with Mg and SAH
分子名称: GLYCEROL, MAGNESIUM ION, Norbelladine, ...
著者Saw, Y.Y.H, Nakashima, Y, Morita, H.
登録日2024-05-08
公開日2024-08-07
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases
Acs Catalysis, 2024
8Z8S
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norbelladine 4'-O-methyltransferase S52M Y186F complexed with Mg and SAH
分子名称: GLYCEROL, MAGNESIUM ION, Norbelladine 4'-O-methyltransferase, ...
著者Saw, Y.Y.H, Nakashima, Y, Morita, H.
登録日2024-04-22
公開日2024-08-07
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases
Acs Catalysis, 2024
8Z8P
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norbelladine 4'-O-methyltransferase S52M variant complexed with Mg and SAH
分子名称: GLYCEROL, MAGNESIUM ION, Norbelladine 4'-O-methyltransferase, ...
著者Saw, Y.Y.H, Nakashima, Y, Morita, H.
登録日2024-04-22
公開日2024-08-07
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases
Acs Catalysis, 2024
8Z8O
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norbelladine 4'-O-methyltransferase Y186F complexed with Mg and SAH
分子名称: GLYCEROL, MAGNESIUM ION, Norbelladine 4'-O-methyltransferase, ...
著者Saw, Y.Y.H, Nakashima, Y, Morita, H.
登録日2024-04-22
公開日2024-08-07
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases
Acs Catalysis, 2024

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