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PDB: 439 件

1MGT
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CRYSTAL STRUCTURE OF O6-METHYLGUANINE-DNA METHYLTRANSFERASE FROM HYPERTHERMOPHILIC ARCHAEON PYROCOCCUS KODAKARAENSIS STRAIN KOD1
分子名称: PROTEIN (O6-METHYLGUANINE-DNA METHYLTRANSFERASE), SULFATE ION
著者Hashimoto, H, Inoue, T, Nishioka, M, Fujiwara, S, Takagi, M, Imanaka, T, Kai, Y.
登録日1999-01-12
公開日2000-01-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Hyperthermostable protein structure maintained by intra and inter-helix ion-pairs in archaeal O6-methylguanine-DNA methyltransferase.
J.Mol.Biol., 292, 1999
4FNC
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BU of 4fnc by Molmil
Human TDG in a post-reactive complex with 5-hydroxymethyluracil (5hmU)
分子名称: 5-HYDROXYMETHYL URACIL, DNA (28-MER), DNA (29-MER), ...
著者Hashimoto, H, Hong, S, Bhagwat, A.S, Zhang, X, Cheng, X.
登録日2012-06-19
公開日2012-09-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.493 Å)
主引用文献Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation.
Nucleic Acids Res., 40, 2012
6DNZ
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BU of 6dnz by Molmil
Trypanosoma brucei PRMT1 enzyme-prozyme heterotetrameric complex with AdoHcy
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Arginine N-methyltransferase, putative, ...
著者Hashimoto, H, Kafkova, L, Jordan, K, Read, L.K, Debler, E.W.
登録日2018-06-08
公開日2019-06-12
最終更新日2020-02-12
実験手法X-RAY DIFFRACTION (2.384 Å)
主引用文献Structural Basis of Protein Arginine Methyltransferase Activation by a Catalytically Dead Homolog (Prozyme).
J.Mol.Biol., 432, 2020
5CZZ
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BU of 5czz by Molmil
Crystal structure of Staphylococcus aureus Cas9 in complex with sgRNA and target DNA (TTGAAT PAM)
分子名称: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, DNA (28-MER), ...
著者Nishimasu, H, Ishitani, R, Nureki, O.
登録日2015-08-01
公開日2015-09-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Staphylococcus aureus Cas9.
Cell, 162, 2015
6LEH
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BU of 6leh by Molmil
Crystal structure of Autotaxin in complex with an inhibitor
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Nishimasu, H, Osamu, N.
登録日2019-11-25
公開日2020-03-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification of PotentIn VivoAutotaxin Inhibitors that Bind to Both Hydrophobic Pockets and Channels in the Catalytic Domain.
J.Med.Chem., 63, 2020
5K5L
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BU of 5k5l by Molmil
Homo sapiens CCCTC-binding factor (CTCF) ZnF6-8 and H19 sequence DNA complex structure
分子名称: DNA (5'-D(*GP*TP*TP*GP*CP*CP*GP*CP*GP*TP*G)-3'), DNA (5'-D(P*AP*CP*GP*CP*GP*GP*CP*AP*AP*C)-3'), Transcriptional repressor CTCF, ...
著者Hashimoto, H, Cheng, X.
登録日2016-05-23
公開日2017-05-24
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.125 Å)
主引用文献Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
5K5H
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Homo sapiens CCCTC-binding factor (CTCF) ZnF4-7 and DNA complex structure
分子名称: DNA (5'-D(*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*C)-3'), DNA (5'-D(*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*G)-3'), Transcriptional repressor CTCF, ...
著者Hashimoto, H, Cheng, X.
登録日2016-05-23
公開日2017-05-24
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.108 Å)
主引用文献Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
5KE8
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mouse Klf4 E446P ZnF1-3 and MpG/MpG sequence DNA complex structure
分子名称: DNA (5'-D(*GP*AP*GP*GP*(5CM)P*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*GP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-09
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Distinctive Klf4 mutants determine preference for DNA methylation status.
Nucleic Acids Res., 44, 2016
5K5J
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Homo sapiens CCCTC-binding factor (CTCF) ZnF5-8 and DNA complex structure in space group P41212
分子名称: ACETATE ION, DNA (5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*GP*CP*AP*AP*C)-3'), DNA (5'-D(*TP*TP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*G)-3'), ...
著者Hashimoto, H, Cheng, X.
登録日2016-05-23
公開日2017-05-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.287 Å)
主引用文献Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
5KE9
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mouse Klf4 E446P ZnF1-3 and TpG/CpA sequence DNA complex structure
分子名称: DNA (5'-D(*GP*AP*GP*GP*TP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*CP*AP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-09
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.336 Å)
主引用文献Distinctive Klf4 mutants determine preference for DNA methylation status.
Nucleic Acids Res., 44, 2016
5KEA
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BU of 5kea by Molmil
mouse Klf4 ZnF1-3 (E446D) and CpG/CpG sequence DNA complex structure: Form I
分子名称: DNA (5'-D(*GP*AP*GP*GP*CP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*CP*GP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-09
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.458 Å)
主引用文献Distinctive Klf4 mutants determine preference for DNA methylation status.
Nucleic Acids Res., 44, 2016
5KL6
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Wilms Tumor Protein (WT1) Q369R ZnF2-4 in complex with DNA
分子名称: DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*CP*CP*CP*CP*AP*CP*GP*C)-3'), Wilms tumor protein, ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-23
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.641 Å)
主引用文献Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.
Nucleic Acids Res., 44, 2016
5KL4
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Wilms Tumor Protein (WT1) ZnF2-4 Q369H in complex with formylated DNA
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5FC)P*GP*T)-3'), ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-23
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.783 Å)
主引用文献Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.
Nucleic Acids Res., 44, 2016
5KKQ
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BU of 5kkq by Molmil
Homo sapiens CCCTC-binding factor (CTCF) ZnF3-7 and DNA complex structure
分子名称: DNA (5'-D(*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*CP*TP*A)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*GP*C)-3'), Transcriptional repressor CTCF, ...
著者Hashimoto, H, Wang, D, Cheng, X.
登録日2016-06-22
公開日2017-05-24
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.744 Å)
主引用文献Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
5KL5
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BU of 5kl5 by Molmil
Wilms Tumor Protein (WT1) ZnF2-4 Q369H in complex with carboxylated DNA
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(1CC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-23
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.289 Å)
主引用文献Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.
Nucleic Acids Res., 44, 2016
5KL2
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BU of 5kl2 by Molmil
Wilms Tumor Protein (WT1) ZnF2-4 in complex with DNA
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*AP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*TP*CP*CP*CP*AP*CP*GP*C)-3'), ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-23
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.692 Å)
主引用文献Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.
Nucleic Acids Res., 44, 2016
5KL3
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BU of 5kl3 by Molmil
Wilms Tumor Protein (WT1) ZnF2-4 Q369H in complex with DNA
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*AP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*TP*CP*CP*CP*AP*CP*GP*C)-3'), ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-23
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.449 Å)
主引用文献Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.
Nucleic Acids Res., 44, 2016
8XI6
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BU of 8xi6 by Molmil
SARS-CoV-2 Omicron BQ.1.1 Variant Spike Protein Complexed with MO11 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ishimaru, H, Nishimura, M, Shigematsu, H, Marini, M.I, Hasegawa, N, Takamiya, R, Iwata, S, Mori, Y.
登録日2023-12-19
公開日2024-04-24
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Epitopes of an antibody that neutralizes a wide range of SARS-CoV-2 variants in a conserved subdomain 1 of the spike protein.
J.Virol., 98, 2024
3A57
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BU of 3a57 by Molmil
Crystal structure of Thermostable Direct Hemolysin
分子名称: Thermostable direct hemolysin 2
著者Hashimoto, H, Yanagihara, I, Nakahira, K, Hamada, D, Ikegami, T, Mayanagi, K, Kaieda, S, Fukui, T, Ohnishi, K, Kajiyama, S, Yamane, T, Ikeguchi, M, Honda, T, Shimizu, T, Sato, M.
登録日2009-08-03
公開日2010-03-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure and functional characterization of Vibrio parahaemolyticus thermostable direct hemolysin
J.Biol.Chem., 285, 2010
3ALR
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BU of 3alr by Molmil
Crystal structure of Nanos
分子名称: Nanos protein, ZINC ION
著者Hashimoto, H, Hara, K, Hishiki, A, Kawaguchi, S, Shichijo, N, Nakamura, K, Unzai, S, Tamaru, Y, Shimizu, T, Sato, M.
登録日2010-08-06
公開日2011-02-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of zinc-finger domain of Nanos and its functional implications
Embo Rep., 11, 2010
7RDN
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BU of 7rdn by Molmil
Crystal structure of S. cerevisiae pre-mRNA leakage protein 39 (Pml39)
分子名称: Pre-mRNA leakage protein 39, ZINC ION
著者Hashimoto, H, Ramirez, D.H, Pawlak, N, Blobel, G, Palancade, B, Debler, E.W.
登録日2021-07-09
公開日2022-07-27
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structure of the pre-mRNA leakage 39-kDa protein reveals a single domain of integrated zf-C3HC and Rsm1 modules.
Sci Rep, 12, 2022
4GEL
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BU of 4gel by Molmil
Crystal structure of Zucchini
分子名称: 1,2-ETHANEDIOL, Mitochondrial cardiolipin hydrolase, PHOSPHATE ION, ...
著者Nishimasu, H, Fukuhara, S, Ishitani, R, Nureki, O.
登録日2012-08-02
公開日2012-10-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.756 Å)
主引用文献Structure and function of Zucchini endoribonuclease in piRNA biogenesis
Nature, 491, 2012
4GEN
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BU of 4gen by Molmil
Crystal structure of Zucchini (monomer)
分子名称: CHLORIDE ION, Mitochondrial cardiolipin hydrolase
著者Nishimasu, H, Fukuhara, S, Ishitani, R, Nureki, O.
登録日2012-08-02
公開日2012-10-17
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and function of Zucchini endoribonuclease in piRNA biogenesis
Nature, 491, 2012
4GEM
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BU of 4gem by Molmil
Crystal structure of Zucchini (K171A)
分子名称: 1,2-ETHANEDIOL, Mitochondrial cardiolipin hydrolase, ZINC ION
著者Nishimasu, H, Fukuhara, S, Ishitani, R, Nureki, O.
登録日2012-08-02
公開日2012-10-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.206 Å)
主引用文献Structure and function of Zucchini endoribonuclease in piRNA biogenesis
Nature, 491, 2012
1UF8
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Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-Phenylalanine
分子名称: D-[(AMINO)CARBONYL]PHENYLALANINE, N-carbamyl-D-amino acid amidohydrolase
著者Hashimoto, H, Aoki, M, Shimizu, T, Nakai, T, Morikawa, H, Ikenaka, Y, Takahashi, S, Sato, M.
登録日2003-05-26
公開日2004-06-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase
To be published

222415

件を2024-07-10に公開中

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