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PDB: 1896 件

8K73
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Factor-inhibiting hypoxia-inducible factor in complex with Zn(II) and 2-(3-hydroxy-2-((1-(phenylsulfonyl)pyrrolidine-3-carbonyl)imino)-2,3-dihydrothiazol-4-yl)acetic acid
分子名称: 2-[(2~{Z})-3-oxidanyl-2-[(3~{R})-1-(phenylsulfonyl)pyrrolidin-3-yl]carbonylimino-1,3-thiazol-4-yl]ethanoic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ...
著者Nakashima, Y, Corner, T.P, Teo, R.Z.R, Brewitz, L, Schofield, C.J.
登録日2023-07-26
公開日2023-12-13
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structure-guided optimisation of N -hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-alpha.
Chem Sci, 14, 2023
8KI1
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BU of 8ki1 by Molmil
Crystal structure of the holo form of the hemophore HasA from Pseudomonas protegens Pf-5
分子名称: GLYCEROL, Heme acquisition protein HasAp, PHOSPHATE ION, ...
著者Shisaka, Y, Inaba, H, Sugimoto, H, Shoji, O.
登録日2023-08-22
公開日2024-03-27
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Heme-substituted protein assembly bridged by synthetic porphyrin: achieving controlled configuration while maintaining rotational freedom.
Rsc Adv, 14, 2024
8KI0
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BU of 8ki0 by Molmil
Crystal structure of the hemophore HasA from Pseudomonas protegens Pf-5 capturing Fe-tetraphenylporphyrin
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Heme acquisition protein HasAp, ...
著者Shisaka, Y, Inaba, H, Sugimoto, H, Shoji, O.
登録日2023-08-22
公開日2024-03-27
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Heme-substituted protein assembly bridged by synthetic porphyrin: achieving controlled configuration while maintaining rotational freedom.
Rsc Adv, 14, 2024
5B3D
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BU of 5b3d by Molmil
Structure of a flagellar type III secretion chaperone, FlgN
分子名称: Flagella synthesis protein FlgN
著者Nakanishi, Y, Kinoshita, M, Namba, K, Minamino, T, Imada, K.
登録日2016-02-15
公開日2016-06-01
最終更新日2020-02-26
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Rearrangements of alpha-helical structures of FlgN chaperone control the binding affinity for its cognate substrates during flagellar type III export
Mol.Microbiol., 101, 2016
7Y3V
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BU of 7y3v by Molmil
Crystal structure of CdpNPT in complex with harmane
分子名称: 1-methyl-9H-pyrido[3,4-b]indole, Cyclic dipeptide N-prenyltransferase, PHOSPHATE ION
著者Nakashima, Y, Morita, H.
登録日2022-06-13
公開日2023-04-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Catalytic potential of a fungal indole prenyltransferase toward beta-carbolines, harmine and harman, and their prenylation effects on antibacterial activity.
J.Biosci.Bioeng., 134, 2022
7XVJ
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BU of 7xvj by Molmil
Crystal structure of CdpNPT in complex with harmol
分子名称: 1-methyl-9~{H}-pyrido[3,4-b]indol-7-ol, Cyclic dipeptide N-prenyltransferase, PHOSPHATE ION
著者Nakashima, Y, Morita, H.
登録日2022-05-24
公開日2023-04-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Enzymatic formation of a prenyl beta-carboline by a fungal indole prenyltransferase.
J Nat Med, 76, 2022
6KS2
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Structure of anti-Ghrelin receptor antibody
分子名称: Fab7881 Heavy Chain (FabH), Fab7881 Light Chain (FabL)
著者Shiimura, Y, Horita, S, Asada, H, Hirata, K, Iwata, S, Kojima, M.
登録日2019-08-23
公開日2020-08-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.753 Å)
主引用文献Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode.
Nat Commun, 11, 2020
3D79
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Crystal structure of hypothetical protein PH0734.1 from hyperthermophilic archaea Pyrococcus horikoshii OT3
分子名称: Putative uncharacterized protein PH0734
著者Nishimura, Y, Miyazono, K, Sawano, Y, Makino, T, Nagata, K, Tanokura, M.
登録日2008-05-20
公開日2008-12-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal structure of hypothetical protein PH0734.1 from hyperthermophilic archaea Pyrococcus horikoshii OT3.
Proteins, 73, 2008
6OY7
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BU of 6oy7 by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 7 min
分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Shin, Y, Murakami, K.S.
登録日2019-05-14
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6OVY
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BU of 6ovy by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1C
分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*CP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Shin, Y, Murakami, K.S.
登録日2019-05-08
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.999 Å)
主引用文献Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6OVR
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BU of 6ovr by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1G
分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*GP*GP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*GP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Shin, Y, Murakami, K.S.
登録日2019-05-08
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.843 Å)
主引用文献Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6OW3
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BU of 6ow3 by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1T
分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*GP*AP*TP*CP*TP*GP*AP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*TP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Shin, Y, Murakami, K.S.
登録日2019-05-09
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.766 Å)
主引用文献Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6OY6
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BU of 6oy6 by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 5 min
分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*GP*AP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Shin, Y, Murakami, K.S.
登録日2019-05-14
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.096 Å)
主引用文献Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6OY5
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BU of 6oy5 by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 3 min
分子名称: DNA (5'-D(*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*CP*TP*CP*TP*GP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*CP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*AP*T)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Shin, Y, Murakami, K.S.
登録日2019-05-14
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6P70
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BU of 6p70 by Molmil
X-ray crystal structure of bacterial RNA polymerase and pyrBI promoter complex
分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*CP*GP*AP*TP*CP*TP*TP*TP*GP*CP*CP*GP*GP*G)-3'), DNA (5'-D(P*TP*CP*CP*CP*GP*GP*CP*AP*AP*AP*TP*TP*GP*TP*CP*CP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Shin, Y, Murakami, K.S.
登録日2019-06-04
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.052 Å)
主引用文献Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6P71
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BU of 6p71 by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrBI promoter
分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*CP*GP*AP*GP*CP*CP*GP*GP*GP*A)-3'), DNA (5'-D(P*CP*TP*CP*CP*CP*GP*GP*CP*AP*AP*AP*TP*TP*GP*T)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Shin, Y, Murakami, K.S.
登録日2019-06-04
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
7A1O
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BU of 7a1o by Molmil
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II), 4-ethyl-2-oxoglutarate, AND CONSENSUS ANKYRIN REPEAT DOMAIN (20-MER)
分子名称: 4-ethyl-2-oxoglutarate, CONSENSUS ANKYRIN REPEAT DOMAIN, Hypoxia-inducible factor 1-alpha inhibitor, ...
著者Nakashima, Y, Brewitz, L, Schofield, C.J.
登録日2020-08-13
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.
Nat Commun, 12, 2021
7A1Q
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BU of 7a1q by Molmil
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II), 3-(carboxycarbonyl)cyclopentane-1-carboxylic acid, AND CONSENSUS ANKYRIN REPEAT DOMAIN (20-MER)
分子名称: 3-(carboxycarbonyl)cyclopentane-1-carboxylic acid, CONSENSUS ANKYRIN REPEAT DOMAIN, Hypoxia-inducible factor 1-alpha inhibitor, ...
著者Nakashima, Y, Brewitz, L, Schofield, C.J.
登録日2020-08-13
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.
Nat Commun, 12, 2021
7A1P
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BU of 7a1p by Molmil
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II), 4-propyl-2-oxoglutarate, AND CONSENSUS ANKYRIN REPEAT DOMAIN (20-MER)
分子名称: (4~{S})-2-oxidanylidene-4-propyl-pentanedioic acid, CONSENSUS ANKYRIN REPEAT DOMAIN, Hypoxia-inducible factor 1-alpha inhibitor, ...
著者Nakashima, Y, Brewitz, L, Schofield, C.J.
登録日2020-08-13
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.
Nat Commun, 12, 2021
7A1M
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BU of 7a1m by Molmil
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II) AND 3-propyl-2-oxoglutarate
分子名称: 3-propyl-2-oxoglutarate, Hypoxia-inducible factor 1-alpha inhibitor, SULFATE ION, ...
著者Nakashima, Y, Brewitz, L, Schofield, C.J.
登録日2020-08-13
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.
Nat Commun, 12, 2021
7A1N
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BU of 7a1n by Molmil
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II), 3-methyl-2-oxoglutarate, AND CONSENSUS ANKYRIN REPEAT DOMAIN (20-MER)
分子名称: (3~{S})-3-methyl-2-oxidanylidene-pentanedioic acid, CONSENSUS ANKYRIN REPEAT DOMAIN, Hypoxia-inducible factor 1-alpha inhibitor, ...
著者Nakashima, Y, Brewitz, L, Schofield, C.J.
登録日2020-08-13
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.
Nat Commun, 12, 2021
7A1L
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BU of 7a1l by Molmil
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II) AND 3-methyl-2-oxoglutarate
分子名称: (3~{S})-3-methyl-2-oxidanylidene-pentanedioic acid, Hypoxia-inducible factor 1-alpha inhibitor, SULFATE ION, ...
著者Nakashima, Y, Brewitz, L, Schofield, C.J.
登録日2020-08-13
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.
Nat Commun, 12, 2021
7A1J
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BU of 7a1j by Molmil
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II) AND 3-(3-phenylpropyl)-2-oxoglutarate
分子名称: 3-(3-phenylpropyl)-2-oxoglutarate, Hypoxia-inducible factor 1-alpha inhibitor, SULFATE ION, ...
著者Nakashima, Y, Brewitz, L, Schofield, C.J.
登録日2020-08-13
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.
Nat Commun, 12, 2021
7A1S
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BU of 7a1s by Molmil
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II), 3-methyl-2-oxoglutarate, AND TANKYRASE-2 (TNKS2) FRAGMENT PEPTIDE (21-MER)
分子名称: (3~{S})-3-methyl-2-oxidanylidene-pentanedioic acid, Hypoxia-inducible factor 1-alpha inhibitor, SULFATE ION, ...
著者Nakashima, Y, Brewitz, L, Schofield, C.J.
登録日2020-08-13
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.
Nat Commun, 12, 2021
7A1K
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BU of 7a1k by Molmil
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II) AND 3-((9,9-dimethyl-9H-fluoren-2-yl)methyl)-2-oxoglutarate
分子名称: 3-((9,9-dimethyl-9H-fluoren-2-yl)methyl)-2-oxoglutarate, Hypoxia-inducible factor 1-alpha inhibitor, SULFATE ION, ...
著者Nakashima, Y, Brewitz, L, Schofield, C.J.
登録日2020-08-13
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.
Nat Commun, 12, 2021

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件を2024-07-10に公開中

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