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PDB: 1963 件

5ZWM
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Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom (tri-snRNP and U2 snRNP Part)
分子名称: 13 kDa ribonucleoprotein-associated protein, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, ...
著者Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y.
登録日2018-05-16
公開日2018-08-29
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018
6AHD
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The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Brr2, U5 small nuclear ribonucleoprotein 200 kDa helicase, ...
著者Zhan, X, Yan, C, Zhang, X, Shi, Y.
登録日2018-08-17
公開日2018-11-14
最終更新日2021-06-30
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
6AH0
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The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhan, X, Yan, C, Zhang, X, Shi, Y.
登録日2018-08-15
公開日2018-11-14
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
5YGH
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Crystal Structure of the Capsid Protein from Zika Virus
分子名称: Capsid protein
著者Shang, Z, Song, H, Shi, Y, Qi, J, Gao, G.F.
登録日2017-09-23
公開日2018-02-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.884 Å)
主引用文献Crystal Structure of the Capsid Protein from Zika Virus.
J. Mol. Biol., 430, 2018
6AJK
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Crystal structure of TFB1M and h45 in homo sapiens
分子名称: Dimethyladenosine transferase 1, mitochondrial, RNA (28-MER)
著者Liu, X, Shen, S, Wu, P, Li, F, Wang, C, Gong, Q, Wu, J, Zhang, H, Shi, Y.
登録日2018-08-28
公開日2019-06-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献Structural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function.
Nucleic Acids Res., 47, 2019
6AAX
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Crystal structure of TFB1M and h45 with SAM in homo sapiens
分子名称: DI(HYDROXYETHYL)ETHER, Dimethyladenosine transferase 1, mitochondrial, ...
著者Liu, X, Shen, S, Wu, P, Li, F, Gong, Q, Wu, J, Zhang, H, Shi, Y.
登録日2018-07-19
公開日2019-06-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.994 Å)
主引用文献Structural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function.
Nucleic Acids Res., 47, 2019
6A70
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Structure of the human PKD1/PKD2 complex
分子名称: Polycystin-1, Polycystin-2
著者Su, Q, Hu, F, Ge, X, Lei, J, Yu, S, Wang, T, Zhou, Q, Mei, C, Shi, Y.
登録日2018-06-29
公開日2018-08-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of the human PKD1-PKD2 complex.
Science, 361, 2018
1CMN
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CRYSTAL STRUCTURES OF FERRIC-NO COMPLEXES OF FUNGAL NITRIC OXIDE REDUCTASE AND THEIR SER286 MUTANTS AT CRYOGENIC TEMPERATURE
分子名称: CYTOCHROME P450, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE
著者Park, S.-Y, Shiro, Y.
登録日1999-05-07
公開日2000-03-22
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Proton delivery in NO reduction by fungal nitric-oxide reductase. Cryogenic crystallography, spectroscopy, and kinetics of ferric-NO complexes of wild-type and mutant enzymes.
J.Biol.Chem., 275, 2000
2QH6
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Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed with an Oxabicyclic diarylethylene Compound
分子名称: DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE, Estrogen receptor, Nuclear receptor coactivator 2
著者Nettles, K.W, Bruning, J.B, Nowak, J, Sharma, S.K, Hahm, J.B, Shi, Y, Kulp, K, Hochberg, R.B, Zhou, H, Katzenellenbogen, J.A, Katzenellenbogen, B.S, Kim, Y, Joachmiak, A, Greene, G.L.
登録日2007-06-29
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2QXM
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Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed to Burned Meat Compound PhIP
分子名称: 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE, Estrogen receptor, Nuclear receptor coactivator 2
著者Nettles, K.W, Bruning, J.B, Gil, G, Nowak, J, Sharma, S.K, Hahm, J.B, Shi, Y, Kulp, K, Hochberg, R.B, Zhou, H, Katzenellenbogen, J.A, Katzenellenbogen, B.S, Kim, Y, Joachmiak, A, Greene, G.L.
登録日2007-08-12
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2QGT
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Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed to an Ether Estradiol Compound
分子名称: (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL, Estrogen receptor, Nuclear receptor coactivator 2
著者Nettles, K.W, Bruning, J.B, Nowak, J, Sharma, S.K, Hahm, J.B, Shi, Y, Kulp, K, Hochberg, R.B, Zhou, H, Katzenellenbogen, J.A, Katzenellenbogen, B.S, Kim, Y, Joachmiak, A, Greene, G.L.
登録日2007-06-29
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2QA8
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Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Mutant 537S Complexed with Genistein
分子名称: Estrogen receptor, GENISTEIN, nuclear receptor coactivator 2
著者Nettles, K.W, Bruning, J.B, Nowak, J, Sharma, S.K, Hahm, J.B, Shi, Y, Kulp, K, Hochberg, R.B, Zhou, H, Katzenellenbogen, J.A, Katzenellenbogen, B.S, Kim, Y, Joachmiak, A, Greene, G.L.
登録日2007-06-14
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2QAB
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Crystal Structure of Estrogen Receptor Alpha Ligand Binding Domain Mutant 537S Complexed with an Ethyl Indazole Compound
分子名称: 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL, Estrogen receptor, nuclear receptor coactivator 2
著者Nettles, K.W, Bruning, J.B, Nowak, J, Sharma, S.K, Hahm, J.B, Shi, Y, Kulp, K, Hochberg, R.B, Zhou, H, Katzenellenbogen, J.A, Katzenellenbogen, B.S, Kim, Y, Joachmiak, A, Greene, G.L.
登録日2007-06-14
公開日2008-03-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2QA6
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Crystal Structure of Estrogen Receptor Alpha mutant 537S Complexed with 4-(6-hydroxy-1H-indazol-3-yl)benzene-1,3-diol
分子名称: 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL, Estrogen receptor, nuclear receptor coactivator 2
著者Nettles, K.W, Bruning, J.B, Nowak, J, Sharma, S.K, Hahm, J.B, Shi, Y, Kulp, K, Hochberg, R.B, Zhou, H, Katzenellenbogen, J.A, Katzenellenbogen, B.S, Kim, Y, Joachmiak, A, Greene, G.L.
登録日2007-06-14
公開日2008-03-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2NPP
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Structure of the Protein Phosphatase 2A Holoenzyme
分子名称: MANGANESE (II) ION, Protein Phosphatase 2, regulatory subunit A (PR 65), ...
著者Xu, Y, Chen, Y, Xing, Y, Chao, Y, Shi, Y.
登録日2006-10-28
公開日2006-12-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of the protein phosphatase 2A holoenzyme
Cell(Cambridge,Mass.), 127, 2006
2QGW
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Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed with a Chloro-Indazole Compound
分子名称: 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL, Estrogen receptor, Nuclear receptor coactivator 2
著者Nettles, K.W, Bruning, J.B, Nowak, J, Sharma, S.K, Hahm, J.B, Shi, Y, Kulp, K, Hochberg, R.B, Zhou, H, Katzenellenbogen, J.A, Katzenellenbogen, B.S, Kim, Y, Joachmiak, A, Greene, G.L.
登録日2007-06-29
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2NYL
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Crystal structure of Protein Phosphatase 2A (PP2A) holoenzyme with the catalytic subunit carboxyl terminus truncated
分子名称: MANGANESE (II) ION, Protein phosphatase 2, regulatory subunit A (PR 65), ...
著者Xing, Y, Xu, Y, Chen, Y, Chao, Y, Lin, Z, Shi, Y.
登録日2006-11-20
公開日2006-12-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure of the Protein Phosphatase 2A Holoenzyme.
Cell(Cambridge,Mass.), 127, 2006
2NYM
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Crystal Structure of Protein Phosphatase 2A (PP2A) with C-terminus truncated catalytic subunit
分子名称: MANGANESE (II) ION, Protein phosphatase 2, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ...
著者Chen, Y, Xing, Y, Xu, Y, Chao, Y, Lin, Z, Jeffrey, P.D, Shi, Y.
登録日2006-11-21
公開日2006-12-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of the Protein Phosphatase 2A Holoenzyme.
Cell(Cambridge,Mass.), 127, 2006
2MK6
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Structure determination of substrate binding domain of MecA
分子名称: Adapter protein MecA
著者Zhang, Y.-H, Zhang, Y, Jin, C, Shi, Y.
登録日2014-01-29
公開日2015-02-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure and interaction analysis of the substrate binding domain of MecA
To be Published
2JWE
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Solution structure of the second PDZ domain from human zonula occludens-1: A dimeric form with 3D domain swapping
分子名称: Tight junction protein ZO-1
著者Ji, P, Wu, J.W, Zhang, J.H, Yang, Y.S, Wu, J.H, Shi, Y.Y.
登録日2007-10-10
公開日2007-10-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the second PDZ domain of Zonula Occludens 1
Proteins, 79, 2011
3FHP
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A neutron crystallographic analysis of a porcine 2Zn insulin at 2.0 A resolution
分子名称: Insulin, ZINC ION
著者Iwai, W, Kurihara, K, Yamada, T, Kobayashi, Y, Ohnishi, Y, Tanaka, I, Takahashi, H, Niimura, N.
登録日2008-12-09
公開日2009-10-20
最終更新日2023-11-01
実験手法NEUTRON DIFFRACTION (2 Å)
主引用文献A neutron crystallographic analysis of T6 porcine insulin at 2.1 A resolution
Acta Crystallogr.,Sect.D, 65, 2009
2M80
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Solution structure of yeast dithiol glutaredoxin Grx8
分子名称: Glutaredoxin-8
著者Tang, Y, Zhang, J, Yu, J, Wu, J, Zhou, C.Z, Shi, Y.
登録日2013-05-02
公開日2014-05-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure-guided activity enhancement and catalytic mechanism of yeast grx8
Biochemistry, 53, 2014
2IRP
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Crystal structure of the l-fuculose-1-phosphate aldolase (aq_1979) from aquifex aeolicus VF5
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, Putative aldolase class 2 protein aq_1979
著者Jeyakanthan, J, Gayathri, D, Yogavel, M, Velmurugan, D, Baba, S, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-10-16
公開日2007-10-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the l-fuculose-1-phosphate aldolase (aq_1979) from aquifex aeolicus VF5
To be Published
2JXW
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Solution Structure of the Tandem WW Domains of FBP21
分子名称: WW domain-binding protein 4
著者Huang, X, Zhang, J, Wu, J, Shi, Y.
登録日2007-11-30
公開日2008-12-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and function of the two tandem WW domains of the pre-mRNA splicing factor FBP21 (formin-binding protein 21)
J.Biol.Chem., 284, 2009
2MOX
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solution structure of tandem SH3 domain of Sorbin and SH3 domain-containing protein 1
分子名称: Sorbin and SH3 domain-containing protein 1
著者Zhao, D, Wang, C, Zhang, J, Wu, J, Shi, Y, Zhang, Z, Gong, Q.
登録日2014-05-07
公開日2014-05-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014

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