2PKU
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![BU of 2pku by Molmil](/molmil-images/mine/2pku) | Solution structure of PICK1 PDZ in complex with the carboxyl tail peptide of GluR2 | 分子名称: | PRKCA-binding protein, peptide (GLU)(SER)(VAL)(LYS)(ILE) | 著者 | Pan, L, Wu, H, Shen, C, Shi, Y, Xia, J, Zhang, M. | 登録日 | 2007-04-18 | 公開日 | 2007-11-20 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes Embo J., 26, 2007
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2PPH
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2Q0O
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![BU of 2q0o by Molmil](/molmil-images/mine/2q0o) | Crystal structure of an anti-activation complex in bacterial quorum sensing | 分子名称: | 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE, Probable transcriptional activator protein traR, Probable transcriptional repressor traM | 著者 | Chen, G, Jeffrey, P.D, Fuqua, C, Shi, Y, Chen, L. | 登録日 | 2007-05-22 | 公開日 | 2007-09-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for antiactivation in bacterial quorum sensing. Proc.Natl.Acad.Sci.Usa, 104, 2007
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4I5J
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![BU of 4i5j by Molmil](/molmil-images/mine/4i5j) | PP2A PR70 Holoenzyme | 分子名称: | CALCIUM ION, Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha | 著者 | Xing, Y, Jeffery, P.D, Shi, Y. | 登録日 | 2012-11-28 | 公開日 | 2013-05-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.091 Å) | 主引用文献 | Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation. Cell Res., 23, 2013
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4I5K
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5YYZ
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![BU of 5yyz by Molmil](/molmil-images/mine/5yyz) | Crystal structure of the MEK1 FHA domain in complex with the HOP1 pThr318 peptide. | 分子名称: | Meiosis-specific protein HOP1, Meiosis-specific serine/threonine-protein kinase MEK1 | 著者 | Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y. | 登録日 | 2017-12-11 | 公開日 | 2018-10-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | 主引用文献 | Structural insights into the recognition of phosphorylated Hop1 by Mek1 Acta Crystallogr D Struct Biol, 74, 2018
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5Z4M
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![BU of 5z4m by Molmil](/molmil-images/mine/5z4m) | Structure of TailorD343A with bound UTP and Mg | 分子名称: | MAGNESIUM ION, Terminal uridylyltransferase Tailor, URIDINE 5'-TRIPHOSPHATE | 著者 | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | 登録日 | 2018-01-11 | 公開日 | 2018-10-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor. Nucleic Acids Res., 47, 2019
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5Z4D
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![BU of 5z4d by Molmil](/molmil-images/mine/5z4d) | Structure of Tailor in complex with AGUU RNA | 分子名称: | RNA (5'-R(*AP*GP*UP*U)-3'), Terminal uridylyltransferase Tailor | 著者 | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | 登録日 | 2018-01-11 | 公開日 | 2018-10-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | 主引用文献 | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor. Nucleic Acids Res., 47, 2019
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5Z4C
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![BU of 5z4c by Molmil](/molmil-images/mine/5z4c) | Crystal structure of Tailor | 分子名称: | Terminal uridylyltransferase Tailor | 著者 | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | 登録日 | 2018-01-10 | 公開日 | 2018-10-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor. Nucleic Acids Res., 47, 2019
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5Z4J
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![BU of 5z4j by Molmil](/molmil-images/mine/5z4j) | Structure of Tailor in complex with U4 RNA | 分子名称: | RNA (5'-R(*UP*UP*UP*U)-3'), Terminal uridylyltransferase Tailor | 著者 | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | 登録日 | 2018-01-11 | 公開日 | 2018-10-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor. Nucleic Acids Res., 47, 2019
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5Z4A
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![BU of 5z4a by Molmil](/molmil-images/mine/5z4a) | Structure of Tailor in complex with AGU RNA | 分子名称: | RNA (5'-R(*AP*GP*U)-3'), Terminal uridylyltransferase Tailor | 著者 | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | 登録日 | 2018-01-10 | 公開日 | 2018-10-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.637 Å) | 主引用文献 | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor. Nucleic Acids Res., 47, 2019
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5YYX
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![BU of 5yyx by Molmil](/molmil-images/mine/5yyx) | Crystal Structure of the MEK1 FHA domain | 分子名称: | Meiosis-specific serine/threonine-protein kinase MEK1 | 著者 | Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y. | 登録日 | 2017-12-11 | 公開日 | 2018-10-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.684 Å) | 主引用文献 | Structural insights into the recognition of phosphorylated Hop1 by Mek1 Acta Crystallogr D Struct Biol, 74, 2018
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5Y1U
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![BU of 5y1u by Molmil](/molmil-images/mine/5y1u) | Crystal structure of RBBP4 bound to AEBP2 RRK motif | 分子名称: | Histone-binding protein RBBP4, SULFATE ION, Zinc finger protein AEBP2 | 著者 | Sun, A, Li, F, Wu, J, Shi, Y. | 登録日 | 2017-07-21 | 公開日 | 2018-04-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.141 Å) | 主引用文献 | Structural and biochemical insights into human zinc finger protein AEBP2 reveals interactions with RBBP4 Protein Cell, 2017
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5YLZ
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![BU of 5ylz by Molmil](/molmil-images/mine/5ylz) | Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. | 登録日 | 2017-10-20 | 公開日 | 2018-07-18 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae Cell, 171, 2017
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8J3S
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![BU of 8j3s by Molmil](/molmil-images/mine/8j3s) | Complex structure of human cytomegalovirus protease and a macrocyclic peptide ligand | 分子名称: | Assemblin, PHE-ILE-THR-GLY-HIS-TYR-TRP-VAL-ARG-PHE-LEU-PRO-CYS-GLY | 著者 | Yoshida, S, Sako, Y, Nikaido, E, Ueda, T, Kozono, I, Ichihashi, Y, Nakahashi, A, Onishi, M, Yamatsu, Y, Kato, T, Nishikawa, J, Tachibana, Y. | 登録日 | 2023-04-18 | 公開日 | 2023-11-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Peptide-to-Small Molecule: Discovery of Non-Covalent, Active-Site Inhibitors of beta-Herpesvirus Proteases. Acs Med.Chem.Lett., 14, 2023
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8J3T
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![BU of 8j3t by Molmil](/molmil-images/mine/8j3t) | Complex structure of human cytomegalovirus protease and a non-covalent small-molecule ligand | 分子名称: | (4R)-1-[1-[(S)-[1-cyclopentyl-3-(2-methylphenyl)pyrazol-4-yl]-(4-methylphenyl)methyl]-2-oxidanylidene-pyridin-3-yl]-3-methyl-2-oxidanylidene-N-(3-oxidanylidene-2-azabicyclo[2.2.2]octan-4-yl)imidazolidine-4-carboxamide, Assemblin | 著者 | Yoshida, S, Sako, Y, Nikaido, E, Ueda, T, Kozono, I, Ichihashi, Y, Nakahashi, A, Onishi, M, Yamatsu, Y, Kato, T, Nishikawa, J, Tachibana, Y. | 登録日 | 2023-04-18 | 公開日 | 2023-11-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Peptide-to-Small Molecule: Discovery of Non-Covalent, Active-Site Inhibitors of beta-Herpesvirus Proteases. Acs Med.Chem.Lett., 14, 2023
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5Y88
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![BU of 5y88 by Molmil](/molmil-images/mine/5y88) | Cryo-EM structure of the intron-lariat spliceosome ready for disassembly from S.cerevisiae at 3.5 angstrom | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat, ... | 著者 | Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. | 登録日 | 2017-08-20 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Structure of an Intron Lariat Spliceosome from Saccharomyces cerevisiae Cell(Cambridge,Mass.), 171, 2017
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5Y0U
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5Z58
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![BU of 5z58 by Molmil](/molmil-images/mine/5z58) | Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | 登録日 | 2018-01-17 | 公開日 | 2018-09-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
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5ZWO
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![BU of 5zwo by Molmil](/molmil-images/mine/5zwo) | Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... | 著者 | Bai, R, Wan, R, Yan, C, Shi, Y. | 登録日 | 2018-05-16 | 公開日 | 2018-08-29 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation Science, 360, 2018
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5YXA
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![BU of 5yxa by Molmil](/molmil-images/mine/5yxa) | Crystal structure of the C-terminal fragment of NS1 protein from yellow fever virus | 分子名称: | Non-structural protein 1 | 著者 | Wang, H, Song, H, Qi, J, Shi, Y, Gao, G.F. | 登録日 | 2017-12-04 | 公開日 | 2018-01-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of the C-terminal fragment of NS1 protein from yellow fever virus. Sci China Life Sci, 60, 2017
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5Z56
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![BU of 5z56 by Molmil](/molmil-images/mine/5z56) | cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | 登録日 | 2018-01-17 | 公開日 | 2018-09-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | 主引用文献 | Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
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5Z57
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![BU of 5z57 by Molmil](/molmil-images/mine/5z57) | Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ALANINE, BUD13 homolog, ... | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | 登録日 | 2018-01-17 | 公開日 | 2018-09-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
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5YZG
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![BU of 5yzg by Molmil](/molmil-images/mine/5yzg) | The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Zhan, X, Yan, C, Zhang, X, Lei, J, Shi, Y. | 登録日 | 2017-12-14 | 公開日 | 2018-08-08 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structure of a human catalytic step I spliceosome Science, 359, 2018
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5ZWN
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![BU of 5zwn by Molmil](/molmil-images/mine/5zwn) | Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.3 angstrom (Part II: U1 snRNP region) | 分子名称: | 56 kDa U1 small nuclear ribonucleoprotein component, Pre-mRNA-processing factor 39, Pre-mRNA-splicing ATP-dependent RNA helicase PRP28, ... | 著者 | Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y. | 登録日 | 2018-05-16 | 公開日 | 2018-08-29 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation Science, 360, 2018
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