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PDB: 1963 件

2PKU
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Solution structure of PICK1 PDZ in complex with the carboxyl tail peptide of GluR2
分子名称: PRKCA-binding protein, peptide (GLU)(SER)(VAL)(LYS)(ILE)
著者Pan, L, Wu, H, Shen, C, Shi, Y, Xia, J, Zhang, M.
登録日2007-04-18
公開日2007-11-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes
Embo J., 26, 2007
2PPH
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BU of 2pph by Molmil
solution structure of human MEKK3 PB1 domain
分子名称: Mitogen-activated protein kinase kinase kinase 3
著者Hu, Q, Zhang, J, Wu, J, Shi, Y.
登録日2007-04-30
公開日2007-05-22
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Insight into the Binding Properties of MEKK3 PB1 to MEK5 PB1 from Its Solution Structure.
Biochemistry, 46, 2007
2Q0O
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Crystal structure of an anti-activation complex in bacterial quorum sensing
分子名称: 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE, Probable transcriptional activator protein traR, Probable transcriptional repressor traM
著者Chen, G, Jeffrey, P.D, Fuqua, C, Shi, Y, Chen, L.
登録日2007-05-22
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for antiactivation in bacterial quorum sensing.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4I5J
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PP2A PR70 Holoenzyme
分子名称: CALCIUM ION, Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
著者Xing, Y, Jeffery, P.D, Shi, Y.
登録日2012-11-28
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.091 Å)
主引用文献Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Cell Res., 23, 2013
4I5K
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PP2A PR70 Holoenzyme model3_diCa_rcsb.pdb bppnat5_extend.mtz
分子名称: CALCIUM ION, Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
著者Xing, Y, Jeffrey, P.D, Shi, Y.
登録日2012-11-28
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Cell Res., 23, 2013
5YYZ
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Crystal structure of the MEK1 FHA domain in complex with the HOP1 pThr318 peptide.
分子名称: Meiosis-specific protein HOP1, Meiosis-specific serine/threonine-protein kinase MEK1
著者Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y.
登録日2017-12-11
公開日2018-10-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献Structural insights into the recognition of phosphorylated Hop1 by Mek1
Acta Crystallogr D Struct Biol, 74, 2018
5Z4M
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Structure of TailorD343A with bound UTP and Mg
分子名称: MAGNESIUM ION, Terminal uridylyltransferase Tailor, URIDINE 5'-TRIPHOSPHATE
著者Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q.
登録日2018-01-11
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
5Z4D
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Structure of Tailor in complex with AGUU RNA
分子名称: RNA (5'-R(*AP*GP*UP*U)-3'), Terminal uridylyltransferase Tailor
著者Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q.
登録日2018-01-11
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
5Z4C
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Crystal structure of Tailor
分子名称: Terminal uridylyltransferase Tailor
著者Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q.
登録日2018-01-10
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
5Z4J
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Structure of Tailor in complex with U4 RNA
分子名称: RNA (5'-R(*UP*UP*UP*U)-3'), Terminal uridylyltransferase Tailor
著者Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q.
登録日2018-01-11
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
5Z4A
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BU of 5z4a by Molmil
Structure of Tailor in complex with AGU RNA
分子名称: RNA (5'-R(*AP*GP*U)-3'), Terminal uridylyltransferase Tailor
著者Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q.
登録日2018-01-10
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.637 Å)
主引用文献Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
5YYX
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Crystal Structure of the MEK1 FHA domain
分子名称: Meiosis-specific serine/threonine-protein kinase MEK1
著者Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y.
登録日2017-12-11
公開日2018-10-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.684 Å)
主引用文献Structural insights into the recognition of phosphorylated Hop1 by Mek1
Acta Crystallogr D Struct Biol, 74, 2018
5Y1U
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Crystal structure of RBBP4 bound to AEBP2 RRK motif
分子名称: Histone-binding protein RBBP4, SULFATE ION, Zinc finger protein AEBP2
著者Sun, A, Li, F, Wu, J, Shi, Y.
登録日2017-07-21
公開日2018-04-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.141 Å)
主引用文献Structural and biochemical insights into human zinc finger protein AEBP2 reveals interactions with RBBP4
Protein Cell, 2017
5YLZ
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BU of 5ylz by Molmil
Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
著者Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y.
登録日2017-10-20
公開日2018-07-18
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae
Cell, 171, 2017
8J3S
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BU of 8j3s by Molmil
Complex structure of human cytomegalovirus protease and a macrocyclic peptide ligand
分子名称: Assemblin, PHE-ILE-THR-GLY-HIS-TYR-TRP-VAL-ARG-PHE-LEU-PRO-CYS-GLY
著者Yoshida, S, Sako, Y, Nikaido, E, Ueda, T, Kozono, I, Ichihashi, Y, Nakahashi, A, Onishi, M, Yamatsu, Y, Kato, T, Nishikawa, J, Tachibana, Y.
登録日2023-04-18
公開日2023-11-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Peptide-to-Small Molecule: Discovery of Non-Covalent, Active-Site Inhibitors of beta-Herpesvirus Proteases.
Acs Med.Chem.Lett., 14, 2023
8J3T
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Complex structure of human cytomegalovirus protease and a non-covalent small-molecule ligand
分子名称: (4R)-1-[1-[(S)-[1-cyclopentyl-3-(2-methylphenyl)pyrazol-4-yl]-(4-methylphenyl)methyl]-2-oxidanylidene-pyridin-3-yl]-3-methyl-2-oxidanylidene-N-(3-oxidanylidene-2-azabicyclo[2.2.2]octan-4-yl)imidazolidine-4-carboxamide, Assemblin
著者Yoshida, S, Sako, Y, Nikaido, E, Ueda, T, Kozono, I, Ichihashi, Y, Nakahashi, A, Onishi, M, Yamatsu, Y, Kato, T, Nishikawa, J, Tachibana, Y.
登録日2023-04-18
公開日2023-11-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Peptide-to-Small Molecule: Discovery of Non-Covalent, Active-Site Inhibitors of beta-Herpesvirus Proteases.
Acs Med.Chem.Lett., 14, 2023
5Y88
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Cryo-EM structure of the intron-lariat spliceosome ready for disassembly from S.cerevisiae at 3.5 angstrom
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat, ...
著者Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y.
登録日2017-08-20
公開日2018-08-01
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Structure of an Intron Lariat Spliceosome from Saccharomyces cerevisiae
Cell(Cambridge,Mass.), 171, 2017
5Y0U
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The solution structure of AEBP2 C2H2 zinc fingers
分子名称: ZINC ION, Zinc finger protein AEBP2
著者Sun, A, Shi, Y, Wu, J.
登録日2017-07-18
公開日2018-08-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural and biochemical insights into human zinc finger protein AEBP2 reveals interactions with RBBP4.
Protein Cell, 9, 2018
5Z58
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Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom.
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
著者Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y.
登録日2018-01-17
公開日2018-09-19
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
5ZWO
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Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom
分子名称: 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ...
著者Bai, R, Wan, R, Yan, C, Shi, Y.
登録日2018-05-16
公開日2018-08-29
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018
5YXA
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Crystal structure of the C-terminal fragment of NS1 protein from yellow fever virus
分子名称: Non-structural protein 1
著者Wang, H, Song, H, Qi, J, Shi, Y, Gao, G.F.
登録日2017-12-04
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the C-terminal fragment of NS1 protein from yellow fever virus.
Sci China Life Sci, 60, 2017
5Z56
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cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom.
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
著者Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y.
登録日2018-01-17
公開日2018-09-19
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
5Z57
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Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ALANINE, BUD13 homolog, ...
著者Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y.
登録日2018-01-17
公開日2018-09-19
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
5YZG
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The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Zhan, X, Yan, C, Zhang, X, Lei, J, Shi, Y.
登録日2017-12-14
公開日2018-08-08
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structure of a human catalytic step I spliceosome
Science, 359, 2018
5ZWN
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Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.3 angstrom (Part II: U1 snRNP region)
分子名称: 56 kDa U1 small nuclear ribonucleoprotein component, Pre-mRNA-processing factor 39, Pre-mRNA-splicing ATP-dependent RNA helicase PRP28, ...
著者Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y.
登録日2018-05-16
公開日2018-08-29
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018

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