4WUA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wua by Molmil](/molmil-images/mine/4wua) | Crystal structure of human SRPK1 complexed to an inhibitor SRPIN340 | Descriptor: | CITRIC ACID, N-[2-(1-piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide, SRSF protein kinase 1, ... | Authors: | Hoshina, M, Ikura, T, Hosoya, T, Hagiwara, M, Ito, N. | Deposit date: | 2014-10-31 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice Mol.Pharmacol., 88, 2015
|
|
4XB3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xb3 by Molmil](/molmil-images/mine/4xb3) | Structure of dextran glucosidase | Descriptor: | CALCIUM ION, Glucan 1,6-alpha-glucosidase, HEXAETHYLENE GLYCOL | Authors: | Kobayashi, M, Kato, K, Yao, M. | Deposit date: | 2014-12-16 | Release date: | 2015-08-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.093 Å) | Cite: | Structural insights into the catalytic reaction that is involved in the reorientation of Trp238 at the substrate-binding site in GH13 dextran glucosidase Febs Lett., 589, 2015
|
|
5B86
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5b86 by Molmil](/molmil-images/mine/5b86) | Crystal structure of M-Sec | Descriptor: | Tumor necrosis factor alpha-induced protein 2 | Authors: | Yamashita, M, Sato, Y, Yamagata, A, Fukai, S. | Deposit date: | 2016-06-12 | Release date: | 2016-10-12 | Last modified: | 2020-02-26 | Method: | X-RAY DIFFRACTION (3.017 Å) | Cite: | Distinct Roles for the N- and C-terminal Regions of M-Sec in Plasma Membrane Deformation during Tunneling Nanotube Formation. Sci Rep, 6, 2016
|
|
8YTN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ytn by Molmil](/molmil-images/mine/8ytn) | Single-chain Fv antibody of E11 | Descriptor: | GLYCEROL, Single-chain Fv antibody of E11 | Authors: | Yoshida, M, Hanazono, Y, Numoto, N, Ito, N, Oda, M. | Deposit date: | 2024-03-26 | Release date: | 2024-07-03 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Affinity-matured antibody with a disulfide bond in H-CDR3 loop. Arch.Biochem.Biophys., 758, 2024
|
|
8YTP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ytp by Molmil](/molmil-images/mine/8ytp) | Single-chain Fv antibody of E11 complex with NP-glycine under reducing conditions | Descriptor: | 2-[2-(3-nitro-4-oxidanyl-phenyl)ethanoylamino]ethanoic acid, Single-chain Fv antibody of E11 | Authors: | Yoshida, M, Hanazono, Y, Numoto, N, Ito, N, Oda, M. | Deposit date: | 2024-03-26 | Release date: | 2024-07-03 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Affinity-matured antibody with a disulfide bond in H-CDR3 loop. Arch.Biochem.Biophys., 758, 2024
|
|
8YTO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yto by Molmil](/molmil-images/mine/8yto) | Single-chain Fv antibody of E11 complex with NP-glycine | Descriptor: | 2-[2-(3-nitro-4-oxidanyl-phenyl)ethanoylamino]ethanoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | Authors: | Yoshida, M, Hanazono, Y, Numoto, N, Ito, N, Oda, M. | Deposit date: | 2024-03-26 | Release date: | 2024-07-03 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.04 Å) | Cite: | Affinity-matured antibody with a disulfide bond in H-CDR3 loop. Arch.Biochem.Biophys., 758, 2024
|
|
6VHF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vhf by Molmil](/molmil-images/mine/6vhf) | Crystal structure of RbBP5 interacting domain of Cfp1 | Descriptor: | PHD-type domain-containing protein, ZINC ION | Authors: | Joshi, M, Couture, J.F. | Deposit date: | 2020-01-09 | Release date: | 2020-01-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.311 Å) | Cite: | A non-canonical monovalent zinc finger stabilizes the integration of Cfp1 into the H3K4 methyltransferase complex COMPASS. Nucleic Acids Res., 48, 2020
|
|
8Y46
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8y46 by Molmil](/molmil-images/mine/8y46) | Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase bound to L-KDF or L-2,4-DKDF | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, L-2,4-diketo-3-deoxyfuconate, ... | Authors: | Akagashi, M, Watanabe, S. | Deposit date: | 2024-01-30 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase reveals a unique binding mode as a alpha-furanosyl hemiketal of substrates. Sci Rep, 14, 2024
|
|
8Y11
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8y11 by Molmil](/molmil-images/mine/8y11) | |
8Y4B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8y4b by Molmil](/molmil-images/mine/8y4b) | |
8Y4J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8y4j by Molmil](/molmil-images/mine/8y4j) | |
1F75
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1f75 by Molmil](/molmil-images/mine/1f75) | CRYSTAL STRUCTURE OF UNDECAPRENYL DIPHOSPHATE SYNTHASE FROM MICROCOCCUS LUTEUS B-P 26 | Descriptor: | SULFATE ION, UNDECAPRENYL PYROPHOSPHATE SYNTHETASE | Authors: | Fujihashi, M, Zhang, Y.-W, Higuchi, Y, Li, X.-Y, Koyama, T, Miki, K. | Deposit date: | 2000-06-26 | Release date: | 2001-03-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of cis-prenyl chain elongating enzyme, undecaprenyl diphosphate synthase. Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
1GCQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1gcq by Molmil](/molmil-images/mine/1gcq) | CRYSTAL STRUCTURE OF VAV AND GRB2 SH3 DOMAINS | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, VAV PROTO-ONCOGENE | Authors: | Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F. | Deposit date: | 2000-08-08 | Release date: | 2001-08-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Novel recognition mode between Vav and Grb2 SH3 domains. EMBO J., 20, 2001
|
|
1GCP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1gcp by Molmil](/molmil-images/mine/1gcp) | CRYSTAL STRUCTURE OF VAV SH3 DOMAIN | Descriptor: | VAV PROTO-ONCOGENE | Authors: | Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F. | Deposit date: | 2000-08-08 | Release date: | 2001-08-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Novel recognition mode between Vav and Grb2 SH3 domains. EMBO J., 20, 2001
|
|
2ZFD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zfd by Molmil](/molmil-images/mine/2zfd) | The crystal structure of plant specific calcium binding protein AtCBL2 in complex with the regulatory domain of AtCIPK14 | Descriptor: | ACETIC ACID, CALCIUM ION, Calcineurin B-like protein 2, ... | Authors: | Akaboshi, M, Hashimoto, H, Ishida, H, Koizumi, N, Sato, M, Shimizu, T. | Deposit date: | 2007-12-29 | Release date: | 2008-02-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | The crystal structure of plant-specific calcium-binding protein AtCBL2 in complex with the regulatory domain of AtCIPK14 J.Mol.Biol., 377, 2008
|
|
6PFX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pfx by Molmil](/molmil-images/mine/6pfx) | |
1HJR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hjr by Molmil](/molmil-images/mine/1hjr) | |
8XWK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xwk by Molmil](/molmil-images/mine/8xwk) | |
6LTG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ltg by Molmil](/molmil-images/mine/6ltg) | Crystal structure of the Fab fragment of murine monoclonal antibody OHV-3 against Human herpesvirus 6B | Descriptor: | MAGNESIUM ION, antibody Fab fragment H-chain, antibody Fab fragment L-chain | Authors: | Nishimura, M, Novita, B.D, Kato, T, Tjan, L.H, Wang, B, Wakata, A, Poetranto, A.L, Kawabata, A, Tang, H, Aoshi, T, Mori, Y. | Deposit date: | 2020-01-22 | Release date: | 2020-06-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Structural basis for the interaction of human herpesvirus 6B tetrameric glycoprotein complex with the cellular receptor, human CD134. Plos Pathog., 16, 2020
|
|
6V11
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v11 by Molmil](/molmil-images/mine/6v11) | Lon Protease from Yersinia pestis | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | Authors: | Shin, M, Puchades, C, Asmita, A, Puri, N, Adjei, E, Wiseman, R.L, Karzai, A.W, Lander, G.C. | Deposit date: | 2019-11-19 | Release date: | 2020-01-22 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis for distinct operational modes and protease activation in AAA+ protease Lon. Sci Adv, 6, 2020
|
|
5BUN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5bun by Molmil](/molmil-images/mine/5bun) | Crystal structure of an antigenic outer membrane protein ST50 from Salmonella Typhi | Descriptor: | Outer membrane protein, octyl beta-D-glucopyranoside | Authors: | Yoshimura, M, Chuankhayan, P, Lin, C.C, Chen, N.C, Yang, M.C, Fun, H.K. | Deposit date: | 2015-06-04 | Release date: | 2015-12-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Crystal structure of an antigenic outer-membrane protein from Salmonella Typhi suggests a potential antigenic loop and an efflux mechanism. Sci Rep, 5, 2015
|
|
8GZC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gzc by Molmil](/molmil-images/mine/8gzc) | Crystal structure of EP300 HAT domain in complex with compound 10 | Descriptor: | (2~{R},4~{R})-4-fluoranyl-1-[1-(4-methoxyphenyl)cyclohexyl]carbonyl-~{N}-(1~{H}-pyrazolo[4,3-b]pyridin-5-yl)pyrrolidine-2-carboxamide, Histone acetyltransferase p300, ZINC ION | Authors: | Takahashi, M, Hanzawa, H. | Deposit date: | 2022-09-26 | Release date: | 2023-01-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of DS-9300: A Highly Potent, Selective, and Once-Daily Oral EP300/CBP Histone Acetyltransferase Inhibitor. J.Med.Chem., 66, 2023
|
|
1HV0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hv0 by Molmil](/molmil-images/mine/1hv0) | DISSECTING ELECTROSTATIC INTERACTIONS AND THE PH-DEPENDENT ACTIVITY OF A FAMILY 11 GLYCOSIDASE | Descriptor: | ENDO-1,4-BETA-XYLANASE | Authors: | Joshi, M.D, Sidhu, G, Nielsen, J.E, Brayer, G.D, Withers, S.G, McIntosh, L.P. | Deposit date: | 2001-01-05 | Release date: | 2001-09-14 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Dissecting the electrostatic interactions and pH-dependent activity of a family 11 glycosidase. Biochemistry, 40, 2001
|
|
4G7L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4g7l by Molmil](/molmil-images/mine/4g7l) | Crystal Structure of rat Heme oxygenase-1 in complex with Heme and O2 | Descriptor: | FORMIC ACID, Heme oxygenase 1, OXYGEN MOLECULE, ... | Authors: | Sugishima, M, Moffat, K, Noguchi, M. | Deposit date: | 2012-07-20 | Release date: | 2012-10-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discrimination between CO and O(2) in heme oxygenase: comparison of static structures and dynamic conformation changes following CO photolysis. Biochemistry, 51, 2012
|
|
4G99
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4g99 by Molmil](/molmil-images/mine/4g99) | Rat Heme Oxygenase-1 in complex with Heme and CO at 100 K after warming to 160 K | Descriptor: | CARBON MONOXIDE, FORMIC ACID, Heme oxygenase 1, ... | Authors: | Sugishima, M, Moffat, K, Noguchi, M. | Deposit date: | 2012-07-23 | Release date: | 2012-10-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discrimination between CO and O(2) in heme oxygenase: comparison of static structures and dynamic conformation changes following CO photolysis. Biochemistry, 51, 2012
|
|