1IV2
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![BU of 1iv2 by Molmil](/molmil-images/mine/1iv2) | Structure of 2C-Methyl-D-erythritol-2,4-cyclodiphosphate Synthase (bound form CDP) | Descriptor: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Kishida, H, Wada, T, Unzai, S, Kuzuyama, T, Terada, T, Sirouzu, M, Yokoyama, S, Tame, J.R.H, Park, S.-Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-03-11 | Release date: | 2002-09-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure and catalytic mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MECDP) synthase, an enzyme in the non-mevalonate pathway of isoprenoid synthesis. Acta Crystallogr.,Sect.D, 59, 2003
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2QUL
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![BU of 2qul by Molmil](/molmil-images/mine/2qul) | Crystal structure of D-tagatose 3-epimerase from Pseudomonas cichorii at 1.79 A resolution | Descriptor: | D-tagatose 3-epimerase, MANGANESE (II) ION | Authors: | Yoshida, H, Yamada, M, Nishitani, T, Takada, G, Izumori, K, Kamitori, S. | Deposit date: | 2007-08-06 | Release date: | 2007-12-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Crystal structures of D-tagatose 3-epimerase from Pseudomonas cichorii and its complexes with D-tagatose and D-fructose J.Mol.Biol., 374, 2007
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3WAW
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![BU of 3waw by Molmil](/molmil-images/mine/3waw) | Crystal Structure of Autotaxin in Complex with 2BoA | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2013-05-09 | Release date: | 2013-07-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.954 Å) | Cite: | Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
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3WAX
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![BU of 3wax by Molmil](/molmil-images/mine/3wax) | Crystal Structure of Autotaxin in Complex with 3BoA | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2013-05-09 | Release date: | 2013-07-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.899 Å) | Cite: | Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
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3WAY
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![BU of 3way by Molmil](/molmil-images/mine/3way) | Crystal Structure of Autotaxin in Complex with 4BoA | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2013-05-09 | Release date: | 2013-07-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.746 Å) | Cite: | Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
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3WAV
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![BU of 3wav by Molmil](/molmil-images/mine/3wav) | Crystal Structure of Autotaxin in Complex with Compound 10 | Descriptor: | (5Z)-5-(3,4-dichlorobenzylidene)-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4(5H)-one, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2013-05-09 | Release date: | 2013-07-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.797 Å) | Cite: | Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
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1UF8
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![BU of 1uf8 by Molmil](/molmil-images/mine/1uf8) | Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-Phenylalanine | Descriptor: | D-[(AMINO)CARBONYL]PHENYLALANINE, N-carbamyl-D-amino acid amidohydrolase | Authors: | Hashimoto, H, Aoki, M, Shimizu, T, Nakai, T, Morikawa, H, Ikenaka, Y, Takahashi, S, Sato, M. | Deposit date: | 2003-05-26 | Release date: | 2004-06-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase To be published
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1UF4
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![BU of 1uf4 by Molmil](/molmil-images/mine/1uf4) | Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase | Descriptor: | N-carbamyl-D-amino acid amidohydrolase | Authors: | Hashimoto, H, Aoki, M, Shimizu, T, Nakai, T, Morikawa, H, Ikenaka, Y, Takahashi, S, Sato, M. | Deposit date: | 2003-05-23 | Release date: | 2004-06-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid To be published
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2MQE
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![BU of 2mqe by Molmil](/molmil-images/mine/2mqe) | |
1UF7
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![BU of 1uf7 by Molmil](/molmil-images/mine/1uf7) | Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-valine | Descriptor: | 3-METHYL-2-UREIDO-BUTYRIC ACID, N-carbamyl-D-amino acid amidohydrolase | Authors: | Hashimoto, H, Aoki, M, Shimizu, T, Nakai, T, Morikawa, H, Ikenaka, Y, Takahashi, S, Sato, M. | Deposit date: | 2003-05-26 | Release date: | 2004-06-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase To be published
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1UF5
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![BU of 1uf5 by Molmil](/molmil-images/mine/1uf5) | Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-methionine | Descriptor: | 1,2-ETHANEDIOL, 4-METHYLSULFANYL-2-UREIDO-BUTYRIC ACID, N-carbamyl-D-amino acid amidohydrolase | Authors: | Hashimoto, H, Aoki, M, Shimizu, T, Nakai, T, Morikawa, H, Ikenaka, Y, Takahashi, S, Sato, M. | Deposit date: | 2003-05-23 | Release date: | 2004-06-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of C171A/V236A mutant of N-carbamyl-D-amino acid amidohydrolase To be published
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1V6R
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![BU of 1v6r by Molmil](/molmil-images/mine/1v6r) | Solution Structure of Endothelin-1 with its C-terminal Folding | Descriptor: | Endothelin-1 | Authors: | Takashima, H, Mimura, N, Ohkubo, T, Yoshida, T, Tamaoki, H, Kobayashi, Y. | Deposit date: | 2003-12-03 | Release date: | 2004-03-16 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Distributed Computing and NMR Constraint-Based High-Resolution Structure
Determination: Applied for Bioactive Peptide Endothelin-1 To Determine C-Terminal
Folding J.Am.Chem.Soc., 126, 2004
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3VKM
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![BU of 3vkm by Molmil](/molmil-images/mine/3vkm) | Protease-resistant mutant form of Human Galectin-8 in complex with sialyllactose and lactose | Descriptor: | 1,2-ETHANEDIOL, Galectin-8, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... | Authors: | Yoshida, H, Yamashita, S, Teraoka, M, Nakakita, S, Nishi, N, Kamitori, S. | Deposit date: | 2011-11-18 | Release date: | 2012-09-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | X-ray structure of a protease-resistant mutant form of human galectin-8 with two carbohydrate recognition domains Febs J., 279, 2012
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8JF5
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![BU of 8jf5 by Molmil](/molmil-images/mine/8jf5) | Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAS1440 | Descriptor: | 4-[5-[(3~{R})-3-azanylpyrrolidin-1-yl]carbonyl-2-[2-fluoranyl-4-(2-methyl-2-oxidanyl-propyl)phenyl]phenyl]-2-fluoranyl-benzenecarbonitrile, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Fukushima, H, Machida, T, Yamashita, S, Suzuki, T. | Deposit date: | 2023-05-17 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | TAS1440, a histone H3 competitive LSD1 inhibitor, activates both TGF-beta and notch signaling pathways via INSM1 dissociation in neuroendocrine small cell lung cancer To Be Published
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5XH7
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![BU of 5xh7 by Molmil](/molmil-images/mine/5xh7) | Crystal structure of the Acidaminococcus sp. BV3L6 Cpf1 RR variant in complex with crRNA and target DNA (TCCA PAM) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, CRISPR-associated endonuclease Cpf1, ... | Authors: | Nishimasu, H, Yamano, T, Ishitani, R, Nureki, O. | Deposit date: | 2017-04-19 | Release date: | 2017-06-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1 Mol. Cell, 67, 2017
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5XH6
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![BU of 5xh6 by Molmil](/molmil-images/mine/5xh6) | Crystal structure of the Acidaminococcus sp. BV3L6 Cpf1 RVR variant in complex with crRNA and target DNA (TATA PAM) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, CRISPR-associated endonuclease Cpf1, ... | Authors: | Nishimasu, H, Yamano, T, Ishitani, R, Nureki, O. | Deposit date: | 2017-04-19 | Release date: | 2017-06-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1 Mol. Cell, 67, 2017
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5XGC
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![BU of 5xgc by Molmil](/molmil-images/mine/5xgc) | Crystal structure of SmgGDS-558 | Descriptor: | Rap1 GTPase-GDP dissociation stimulator 1 | Authors: | Shimizu, H, Toma-Fukai, S, Shimizu, T. | Deposit date: | 2017-04-13 | Release date: | 2017-06-28 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding J. Biol. Chem., 292, 2017
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5ZFS
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![BU of 5zfs by Molmil](/molmil-images/mine/5zfs) | Crystal structure of Arthrobacter globiformis M30 sugar epimerase which can produce D-allulose from D-fructose | Descriptor: | ACETATE ION, D-allulose-3-epimerase, MANGANESE (II) ION | Authors: | Yoshida, H, Yoshihara, A, Gullapalli, P.K, Ohtani, K, Akimitsu, K, Izumori, K, Kamitori, S. | Deposit date: | 2018-03-07 | Release date: | 2018-10-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | X-ray structure of Arthrobacter globiformis M30 ketose 3-epimerase for the production of D-allulose from D-fructose. Acta Crystallogr F Struct Biol Commun, 74, 2018
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5ZHX
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![BU of 5zhx by Molmil](/molmil-images/mine/5zhx) | |
1UMG
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![BU of 1umg by Molmil](/molmil-images/mine/1umg) | Crystal structure of fructose-1,6-bisphosphatase | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,6-FRUCTOSE DIPHOSPHATE (LINEAR FORM), 385aa long conserved hypothetical protein, ... | Authors: | Nishimasu, H, Fushinobu, S, Shoun, H, Wakagi, T. | Deposit date: | 2003-09-30 | Release date: | 2004-07-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The first crystal structure of the novel class of fructose-1,6-bisphosphatase present in thermophilic archaea. Structure, 12, 2004
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5XAX
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![BU of 5xax by Molmil](/molmil-images/mine/5xax) | |
5XAW
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![BU of 5xaw by Molmil](/molmil-images/mine/5xaw) | Parallel homodimer structures of voltage-gated sodium channel beta4 for cell-cell adhesion | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, GLYCEROL, Sodium channel subunit beta-4, ... | Authors: | Shimizu, H, Yokoyama, S. | Deposit date: | 2017-03-15 | Release date: | 2017-07-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | Parallel homodimer structures of the extracellular domains of the voltage-gated sodium channel beta 4 subunit explain its role in cell-cell adhesion J. Biol. Chem., 292, 2017
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5YD8
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![BU of 5yd8 by Molmil](/molmil-images/mine/5yd8) | |
3VUY
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![BU of 3vuy by Molmil](/molmil-images/mine/3vuy) | Crystal structure of A20 ZF7 in complex with linear tetraubiquitin | Descriptor: | POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ... | Authors: | Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2012-07-09 | Release date: | 2013-02-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.981 Å) | Cite: | Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
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3VYV
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![BU of 3vyv by Molmil](/molmil-images/mine/3vyv) | Crystal structure of subtilisin NAT at 1.36 | Descriptor: | CALCIUM ION, GLYCEROL, Subtilisin NAT | Authors: | Ushijima, H, Fuchita, N, Kajiwara, T, Motoshima, H, Ueno, G, Watanabe, K. | Deposit date: | 2012-10-03 | Release date: | 2013-10-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Crystal structure of subtilisin NAT at 1.36 TO BE PUBLISHED
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