5XH6
Crystal structure of the Acidaminococcus sp. BV3L6 Cpf1 RVR variant in complex with crRNA and target DNA (TATA PAM)
Summary for 5XH6
| Entry DOI | 10.2210/pdb5xh6/pdb |
| Related | 5XH7 |
| Descriptor | CRISPR-associated endonuclease Cpf1, crRNA, Target DNA strand, ... (8 entities in total) |
| Functional Keywords | nuclease, hydrolase-rna-dna complex, hydrolase/rna/dna |
| Biological source | Acidaminococcus sp. (strain BV3L6) More |
| Total number of polymer chains | 4 |
| Total formula weight | 180246.86 |
| Authors | Nishimasu, H.,Yamano, T.,Ishitani, R.,Nureki, O. (deposition date: 2017-04-19, release date: 2017-06-14, Last modification date: 2023-11-22) |
| Primary citation | Nishimasu, H.,Yamano, T.,Gao, L.,Zhang, F.,Ishitani, R.,Nureki, O. Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1 Mol. Cell, 67:139-147.e2, 2017 Cited by PubMed: 28595896DOI: 10.1016/j.molcel.2017.04.019 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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