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PDB: 1022 results

4H4S
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BU of 4h4s by Molmil
Crystal Structure of Ferredoxin reductase, BphA4 E175C/Q177G mutant (reduced form)
Descriptor: Biphenyl dioxygenase ferredoxin reductase subunit, FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, ...
Authors:Nishizawa, A, Harada, A, Senda, M, Tachihara, Y, Muramatsu, D, Kishigami, S, Mori, S, Sugiyama, K, Senda, T, Kimura, S.
Deposit date:2012-09-18
Release date:2013-10-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Random Mutagenesis with the Project Assessment for Complete Conversion of Co-Factor Specificity of a Ferredoxin Reductase BphA4
To be Published
5I4N
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BU of 5i4n by Molmil
Crystal Structure of the E596A V617F Mutant JAK2 Pseudokinase Domain Bound to Mg-ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Shiau, A.K, Motamedi, A.
Deposit date:2016-02-12
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Uncoupling JAK2 V617F activation from cytokine-induced signalling by modulation of JH2 alpha C helix.
Biochem.J., 473, 2016
7M1V
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BU of 7m1v by Molmil
Structure of Zika virus NS2b-NS3 protease mutant binding the compound NSC86314 in the super-open conformation
Descriptor: 1,2-ETHANEDIOL, 4-(2-{2,4-diamino-5-[2-(4-{[(2E)-1,3-thiazolidin-2-ylidene]sulfamoyl}phenyl)hydrazinyl]phenyl}hydrazinyl)-N-[(2S)-1,3-thiazolidin-2-yl]benzene-1-sulfonamide, CHLORIDE ION, ...
Authors:Aleshin, A.E, Shiryaev, S.A, Liddington, R.C.
Deposit date:2021-03-15
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:To be provided
To Be Published
7EV7
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BU of 7ev7 by Molmil
Bovine heart cytochrome c oxidase in the carbon monoxide-bound fully reduced state at a 50 K
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Shimada, A, Yoshikawa, S, Tsukihara, T.
Deposit date:2021-05-20
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of CO-bound fully reduced state of bovine heart cytochrome c oxidase
To Be Published
3LY2
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BU of 3ly2 by Molmil
Catalytic Domain of Human Phosphodiesterase 4B in Complex with A Coumarin-Based Inhibitor
Descriptor: 8-(cyclopentyloxy)-4-[(3,5-dichloropyridin-4-yl)amino]-7-methoxy-2H-chromen-2-one, MAGNESIUM ION, SULFATE ION, ...
Authors:Shiau, A.K, Coyle, A.R, Hsien, J.H, Staszewski, L.M.
Deposit date:2010-02-26
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Water-soluble PDE4 inhibitors for the treatment of dry eye.
Bioorg.Med.Chem.Lett., 20, 2010
8HFH
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BU of 8hfh by Molmil
CENP-E motor domain in complex with AMPPNP and Mg2+
Descriptor: Centromere-associated protein E, IMIDAZOLE, MAGNESIUM ION, ...
Authors:Shibuya, A, Yokoyama, H.
Deposit date:2022-11-10
Release date:2023-03-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the motor domain of centromere-associated protein E in complex with a non-hydrolysable ATP analogue.
Febs Lett., 597, 2023
2RT3
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BU of 2rt3 by Molmil
Solution structure of the second RRM domain of Nrd1
Descriptor: Negative regulator of differentiation 1
Authors:Kobayashi, A, Kanaba, T, Mishima, M.
Deposit date:2013-04-16
Release date:2014-04-16
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the second RRM domain of Nrd1, a fission yeast MAPK target RNA binding protein, and implication for its RNA recognition and regulation
Biochem.Biophys.Res.Commun., 437, 2013
1IPE
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BU of 1ipe by Molmil
TROPINONE REDUCTASE-II COMPLEXED WITH NADPH
Descriptor: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TROPINONE REDUCTASE-II
Authors:Yamashita, A, Endo, M, Higashi, T, Nakatsu, T, Yamada, Y, Oda, J, Kato, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2001-05-09
Release date:2003-06-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Capturing Enzyme Structure Prior to Reaction Initiation: Tropinone Reductase-II-Substrate Complexes
BIOCHEMISTRY, 42, 2003
1IPF
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BU of 1ipf by Molmil
TROPINONE REDUCTASE-II COMPLEXED WITH NADPH AND TROPINONE
Descriptor: 8-METHYL-8-AZABICYCLO[3,2,1]OCTAN-3-ONE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TROPINONE REDUCTASE-II
Authors:Yamashita, A, Endo, M, Higashi, T, Nakatsu, T, Yamada, Y, Oda, J, Kato, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2001-05-09
Release date:2003-06-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Capturing Enzyme Structure Prior to Reaction Initiation: Tropinone Reductase-II-Substrate Complexes
BIOCHEMISTRY, 42, 2003
3ACO
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BU of 3aco by Molmil
Crystal structure of the EFC/F-BAR domain of human PACSIN2/Syndapin II (2.7 A)
Descriptor: CALCIUM ION, Protein kinase C and casein kinase substrate in neurons protein 2
Authors:Shimada, A, Shirouzu, M, Hanawa-Suetsugu, K, Terada, T, Umehara, T, Suetsugu, S, Yamamoto, M, Yokoyama, S.
Deposit date:2010-01-07
Release date:2010-04-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mapping of the basic amino-acid residues responsible for tubulation and cellular protrusion by the EFC/F-BAR domain of pacsin2/Syndapin II
Febs Lett., 584, 2010
7VVR
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BU of 7vvr by Molmil
Bovine cytochrome c oxidese in CN-bound mixed valence state at 50 K
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Shimada, A, Tsukihara, T.
Deposit date:2021-11-08
Release date:2022-11-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystallographic cyanide-probing for cytochrome c oxidase reveals structural bases suggesting that a putative proton transfer H-pathway pumps protons.
J.Biol.Chem., 299, 2023
7VUW
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BU of 7vuw by Molmil
Bovine heart cytochrome c oxidase in the cyanide-bound fully oxidized state at 50 K
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Shimada, A, Tsukihara, T.
Deposit date:2021-11-04
Release date:2022-11-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic cyanide-probing for cytochrome c oxidase reveals structural bases suggesting that a putative proton transfer H-pathway pumps protons.
J.Biol.Chem., 299, 2023
7YPY
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BU of 7ypy by Molmil
Bovine heart cytochrome c oxidase in fully oxidized state at 1.5 angstrom resolution
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Shimada, A, Tsukihara, T.
Deposit date:2022-08-05
Release date:2022-09-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Mg2+-containing water cluster of mammalian cytochrome c oxidase collects four pumping proton equivalents in each catalytic cycle.
J. Biol. Chem., 291, 2016
3MJG
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BU of 3mjg by Molmil
The structure of a platelet derived growth factor receptor complex
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-type platelet-derived growth factor receptor, ...
Authors:Shim, A.H.R, He, X.
Deposit date:2010-04-12
Release date:2010-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KLR
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BU of 3klr by Molmil
Bovine H-protein at 0.88 angstrom resolution
Descriptor: GLYCEROL, Glycine cleavage system H protein, SULFATE ION
Authors:Higashiura, A, Kurakane, T, Matsuda, M, Suzuki, M, Inaka, K, Sato, M, Tanaka, H, Fujiwara, K, Nakagawa, A.
Deposit date:2009-11-09
Release date:2010-06-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (0.88 Å)
Cite:High-resolution X-ray crystal structure of bovine H-protein at 0.88 A resolution
Acta Crystallogr.,Sect.D, 66, 2010
7XGP
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BU of 7xgp by Molmil
Human renin in complex with compound3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, UNKNOWN LIGAND
Authors:Kashima, A.
Deposit date:2022-04-05
Release date:2022-09-07
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Discovery of SPH3127: A Novel, Highly Potent, and Orally Active Direct Renin Inhibitor.
J.Med.Chem., 65, 2022
3ABH
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BU of 3abh by Molmil
Crystal structure of the EFC/F-BAR domain of human PACSIN2/Syndapin II (2.0 A)
Descriptor: Protein kinase C and casein kinase substrate in neurons protein 2
Authors:Shimada, A, Shirouzu, M, Hanawa-Suetsugu, K, Terada, T, Umehara, T, Suetsugu, S, Yamamoto, M, Yokoyama, S.
Deposit date:2009-12-11
Release date:2010-04-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mapping of the basic amino-acid residues responsible for tubulation and cellular protrusion by the EFC/F-BAR domain of pacsin2/Syndapin II
Febs Lett., 584, 2010
1IQ0
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BU of 1iq0 by Molmil
THERMUS THERMOPHILUS ARGINYL-TRNA SYNTHETASE
Descriptor: ARGINYL-TRNA SYNTHETASE
Authors:Shimada, A, Nureki, O, Goto, M, Takahashi, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2001-05-24
Release date:2001-11-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and mutational studies of the recognition of the arginine tRNA-specific major identity element, A20, by arginyl-tRNA synthetase.
Proc.Natl.Acad.Sci.USA, 98, 2001
6K4Z
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BU of 6k4z by Molmil
Single-chain Fv antibody of C6 COMPLEXED WITH 2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACID
Descriptor: 2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACID, GLYCEROL, SULFATE ION, ...
Authors:Nishiguchi, A, Numoto, N, Ito, N, Azuma, T, Oda, M.
Deposit date:2019-05-27
Release date:2019-09-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Three-dimensional structure of a high affinity anti-(4-hydroxy-3-nitrophenyl)acetyl antibody possessing a glycine residue at position 95 of the heavy chain.
Mol.Immunol., 114, 2019
1L2J
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BU of 1l2j by Molmil
Human Estrogen Receptor beta Ligand-binding Domain in Complex with (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol
Descriptor: (R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE-2,8-DIOL, ESTROGEN RECEPTOR BETA
Authors:Shiau, A.K, Barstad, D, Radek, J.T, Meyers, M.J, Nettles, K.W, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Agard, D.A, Greene, G.L.
Deposit date:2002-02-21
Release date:2002-05-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.
Nat.Struct.Biol., 9, 2002
7TZK
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BU of 7tzk by Molmil
EPS8 SH3 Domain with NleH1 PxxDY Motif
Descriptor: Epidermal growth factor receptor kinase substrate 8, T3SS secreted effector NleH homolog
Authors:Grishin, A.M, Cygler, M.
Deposit date:2022-02-15
Release date:2022-07-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli
Proc.Natl.Acad.Sci.USA, 119, 2022
7XGO
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BU of 7xgo by Molmil
Human renin in complex with compound2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, UNKNOWN LIGAND
Authors:Kashima, A.
Deposit date:2022-04-05
Release date:2022-08-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of Novel 2-Carbamoyl Morpholine Derivatives as Highly Potent and Orally Active Direct Renin Inhibitors.
Acs Med.Chem.Lett., 13, 2022
7XGK
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BU of 7xgk by Molmil
Human renin in complex with compound1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, UNKNOWN LIGAND
Authors:Kashima, A.
Deposit date:2022-04-05
Release date:2022-08-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of Novel 2-Carbamoyl Morpholine Derivatives as Highly Potent and Orally Active Direct Renin Inhibitors.
Acs Med.Chem.Lett., 13, 2022
1L2I
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BU of 1l2i by Molmil
Human Estrogen Receptor alpha Ligand-binding Domain in Complex with (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol and a Glucocorticoid Receptor Interacting Protein 1 NR box II Peptide
Descriptor: (R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE-2,8-DIOL, CHLORIDE ION, ESTROGEN RECEPTOR, ...
Authors:Shiau, A.K, Barstad, D, Radek, J.T, Meyers, M.J, Nettles, K.W, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Agard, D.A, Greene, G.L.
Deposit date:2002-02-21
Release date:2002-05-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.
Nat.Struct.Biol., 9, 2002
6K3N
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BU of 6k3n by Molmil
Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with BPA-monoF
Descriptor: 2-fluoranyl-4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, Estrogen-related receptor gamma
Authors:Matsushima, A, Nose, T, Kakuta, Y.
Deposit date:2019-05-21
Release date:2020-05-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Evaluation of the Influence of Halogenation on the Binding of Bisphenol A to the Estrogen-Related Receptor gamma.
Chem.Res.Toxicol., 33, 2020

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数据于2024-06-26公开中

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