3IIH
Crystal structure of mouse Bcl-xl (wt) at pH 6.0
Summary for 3IIH
Entry DOI | 10.2210/pdb3iih/pdb |
Related | 3IHC 3IHD 3IHE 3IHF 3IIG |
Descriptor | Bcl-2-like protein 1 (1 entity in total) |
Functional Keywords | apoptosis, bh3 domain, bcl-2, membrane, mitochondrion, transmembrane |
Biological source | Mus musculus (mouse) |
Cellular location | Mitochondrion membrane; Single-pass membrane protein. Isoform Bcl-X(L): Mitochondrion inner membrane. Isoform Bcl-X(delta-TM): Cytoplasm: Q64373 |
Total number of polymer chains | 1 |
Total formula weight | 22056.21 |
Authors | Priyadarshi, A.,Hwang, K.Y. (deposition date: 2009-08-01, release date: 2010-04-14, Last modification date: 2023-11-01) |
Primary citation | Priyadarshi, A.,Roy, A.,Kim, K.S.,Kim, E.E.,Hwang, K.Y. Structural insights into mouse anti-apoptotic Bcl-xl reveal affinity for Beclin 1 and gossypol. Biochem.Biophys.Res.Commun., 394:515-521, 2010 Cited by PubMed: 20206602DOI: 10.1016/j.bbrc.2010.03.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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