2FWV
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![BU of 2fwv by Molmil](/molmil-images/mine/2fwv) | Crystal Structure of Rv0813 | Descriptor: | 1,4-DIETHYLENE DIOXIDE, GLYCEROL, hypothetical protein MtubF_01000852 | Authors: | Shepard, W, Haouz, A, Grana, M, Buschiazzo, A, Betton, J.M, Cole, S.T, Alzari, P.M, Structural Proteomics in Europe (SPINE) | Deposit date: | 2006-02-03 | Release date: | 2006-08-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Crystal Structure of Rv0813c from Mycobacterium tuberculosis Reveals a New Family of Fatty Acid-Binding Protein-Like Proteins in Bacteria J.Bacteriol., 189, 2007
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4TZH
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![BU of 4tzh by Molmil](/molmil-images/mine/4tzh) | Structure of Leptospira interrogans LRR protein LIC12234 | Descriptor: | ACETATE ION, CHLORIDE ION, LIC12234, ... | Authors: | Shepard, W, Saul, F.A, Haouz, A, Picardeau, M. | Deposit date: | 2014-07-10 | Release date: | 2015-06-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Structural characterization of a novel subfamily of leucine-rich repeat proteins from the human pathogen Leptospira interrogans. Acta Crystallogr.,Sect.D, 71, 2015
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4U06
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![BU of 4u06 by Molmil](/molmil-images/mine/4u06) | Structure of Leptospira interrogans LRR protein LIC10831 | Descriptor: | CHLORIDE ION, LIC10831, ZINC ION | Authors: | Shepard, W, Saul, F.A, Haouz, A, Picardeau, M. | Deposit date: | 2014-07-11 | Release date: | 2015-06-03 | Last modified: | 2015-06-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural characterization of a novel subfamily of leucine-rich repeat proteins from the human pathogen Leptospira interrogans. Acta Crystallogr.,Sect.D, 71, 2015
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4U08
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![BU of 4u08 by Molmil](/molmil-images/mine/4u08) | Structure of Leptospira interrogans LRR protein LIC11098 | Descriptor: | CALCIUM ION, LIC11098, SULFATE ION, ... | Authors: | Shepard, W, Saul, F.A, Haouz, A, Picardeau, M. | Deposit date: | 2014-07-11 | Release date: | 2015-06-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural characterization of a novel subfamily of leucine-rich repeat proteins from the human pathogen Leptospira interrogans. Acta Crystallogr.,Sect.D, 71, 2015
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4U09
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![BU of 4u09 by Molmil](/molmil-images/mine/4u09) | Structure of Leptospira interrogans LRR protein LIC12759 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Shepard, W, Saul, F.A, Haouz, A, Picardeau, M. | Deposit date: | 2014-07-11 | Release date: | 2015-06-03 | Last modified: | 2015-06-17 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural characterization of a novel subfamily of leucine-rich repeat proteins from the human pathogen Leptospira interrogans. Acta Crystallogr.,Sect.D, 71, 2015
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2Y75
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![BU of 2y75 by Molmil](/molmil-images/mine/2y75) | The Structure of CymR (YrzC) the Global Cysteine Regulator of B. subtilis | Descriptor: | CHLORIDE ION, HTH-TYPE TRANSCRIPTIONAL REGULATOR CYMR, SULFATE ION | Authors: | Shepard, W, Soutourina, O, Courtois, E, England, P, Haouz, A, Martin-Verstraete, I. | Deposit date: | 2011-01-28 | Release date: | 2011-08-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights Into the Rrf2 Repressor Family - the Structure of Cymr, the Global Cysteine Regulator of Bacillus Subtilis. FEBS J., 278, 2011
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5K1J
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![BU of 5k1j by Molmil](/molmil-images/mine/5k1j) | Human TTR altered by a rhenium tris-carbonyl Pyta-C8 derivative | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DIMETHYL SULFOXIDE, ... | Authors: | Stura, E.A, Ciccone, L, Shepard, W. | Deposit date: | 2016-05-18 | Release date: | 2016-07-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Human TTR conformation altered by rhenium tris-carbonyl derivatives. J.Struct.Biol., 195, 2016
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6TI9
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![BU of 6ti9 by Molmil](/molmil-images/mine/6ti9) | Human transthyretin (TTR) complexed with (E)-3-(((3,5-dibromo-2-hydroxybenzylidene)amino)oxy)propanoic acid. | Descriptor: | 3-[(~{E})-[3,5-bis(bromanyl)-2-oxidanyl-phenyl]methylideneamino]oxypropanoic acid, GLYCEROL, S-1,2-PROPANEDIOL, ... | Authors: | Ciccone, L, Nencetti, S, Orlandini, E, Rossello, A, Legrand, P, Shepard, W. | Deposit date: | 2019-11-22 | Release date: | 2020-10-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis. Bioorg.Med.Chem., 28, 2020
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6TJN
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![BU of 6tjn by Molmil](/molmil-images/mine/6tjn) | Human transthyretin (TTR) complexed with (E)-3-(((4-hydroxybenzylidene)amino)oxy)propanoic acid | Descriptor: | 3-[(~{E})-(4-hydroxyphenyl)methylideneamino]oxypropanoic acid, Transthyretin | Authors: | Ciccone, L, Shepard, W, Nencetti, S, Orlandini, E, Rossello, A. | Deposit date: | 2019-11-26 | Release date: | 2020-12-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.702 Å) | Cite: | Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis. Bioorg.Med.Chem., 28, 2020
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5K1N
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![BU of 5k1n by Molmil](/molmil-images/mine/5k1n) | Human TTR altered by a rhenium tris-carbonyl Pyta-C12 derivative | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Stura, E.A, Ciccone, L, Shepard, W. | Deposit date: | 2016-05-18 | Release date: | 2016-07-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Human TTR conformation altered by rhenium tris-carbonyl derivatives. J.Struct.Biol., 195, 2016
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1I1P
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![BU of 1i1p by Molmil](/molmil-images/mine/1i1p) | REFINEMENT INCLUDING EXPERIMENTAL MAD PHASES ALLOWS AN EXHAUSTIVE STUDY OF ORDERED SOLVENT MOLECULES FOR A PLATINATED DECANUCLEOTIDE | Descriptor: | 5'-D(*CP*CP*TP*CP*GP*CP*TP*CP*TP*C)-3', 5'-D(*GP*AP*GP*AP*GP*CP*GP*AP*GP*G)-3', Cisplatin, ... | Authors: | Coste, F, Shepard, W, Zelwer, C. | Deposit date: | 2001-02-02 | Release date: | 2002-06-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Description of ordered solvent molecules in a platinated decanucleotide duplex refined at 1.6A resolution against experimental MAD phases. Acta Crystallogr.,Sect.D, 58, 2002
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5N7C
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![BU of 5n7c by Molmil](/molmil-images/mine/5n7c) | Human TTR altered conformation from soaking in CuCl2. | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, COPPER (II) ION, ... | Authors: | Ciccone, L, Savko, M, Shepard, W, Stura, E.A. | Deposit date: | 2017-02-20 | Release date: | 2018-03-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Copper mediated amyloid-beta binding to Transthyretin. Sci Rep, 8, 2018
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5N62
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![BU of 5n62 by Molmil](/molmil-images/mine/5n62) | Human TTR crystals soaked in manganese chloride. | Descriptor: | MANGANESE (II) ION, Transthyretin | Authors: | Ciccone, L, Savko, M, Shepard, W, Stura, E.A. | Deposit date: | 2017-02-14 | Release date: | 2018-03-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Copper mediated amyloid-beta binding to Transthyretin. Sci Rep, 8, 2018
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5N5Q
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![BU of 5n5q by Molmil](/molmil-images/mine/5n5q) | Human TTR altered conformation from soaking in iron chloride. | Descriptor: | ACETATE ION, FE (III) ION, Transthyretin, ... | Authors: | Ciccone, L, Savko, M, Shepard, W, Stura, E.A. | Deposit date: | 2017-02-14 | Release date: | 2018-03-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Copper mediated amyloid-beta binding to Transthyretin. Sci Rep, 8, 2018
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2JFS
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![BU of 2jfs by Molmil](/molmil-images/mine/2jfs) | Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis in complex with cacodylate | Descriptor: | CACODYLATE ION, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Bellinzoni, M, Wehenkel, A, Shepard, W, Alzari, P.M. | Deposit date: | 2007-02-04 | Release date: | 2007-07-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Insights Into the Mechanism of Ppm Ser/Thr Phosphatases from the Atomic Resolution Structures of a Mycobacterial Enzyme Structure, 15, 2007
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2JFT
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![BU of 2jft by Molmil](/molmil-images/mine/2jft) | Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis in complex with sulfate | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, SER-THR PHOSPHATASE MSPP, ... | Authors: | Bellinzoni, M, Wehenkel, A, Shepard, W, Alzari, P.M. | Deposit date: | 2007-02-04 | Release date: | 2007-07-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Insights Into the Mechanism of Ppm Ser/Thr Phosphatases from the Atomic Resolution Structures of a Mycobacterial Enzyme Structure, 15, 2007
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2JFR
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![BU of 2jfr by Molmil](/molmil-images/mine/2jfr) | Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis in complex with phosphate at 0.83 A resolution | Descriptor: | CHLORIDE ION, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Bellinzoni, M, Wehenkel, A, Shepard, W, Alzari, P.M. | Deposit date: | 2007-02-04 | Release date: | 2007-07-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (0.83 Å) | Cite: | Insights Into the Mechanism of Ppm Ser/Thr Phosphatases from the Atomic Resolution Structures of a Mycobacterial Enzyme Structure, 15, 2007
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376D
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![BU of 376d by Molmil](/molmil-images/mine/376d) | A ZIPPER-LIKE DNA DUPLEX D(GCGAAAGCT) | Descriptor: | COBALT HEXAMMINE(III), DNA (5'-D(*GP*(CBR)P*GP*AP*AP*AP*GP*CP*T)-3') | Authors: | Cruse, W.B.T, Shepard, W, Prange, T, delalFortelle, E, Fourme, R. | Deposit date: | 1998-01-22 | Release date: | 1999-10-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A zipper-like duplex in DNA: the crystal structure of d(GCGAAAGCT) at 2.1 A resolution. Structure, 6, 1998
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2UYQ
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![BU of 2uyq by Molmil](/molmil-images/mine/2uyq) | Crystal structure of ML2640c from Mycobacterium leprae in complex with S-adenosylmethionine | Descriptor: | HYPOTHETICAL PROTEIN ML2640, S-ADENOSYLMETHIONINE | Authors: | Grana, M, Buschiazzo, A, Wehenkel, A, Haouz, A, Miras, I, Shepard, W, Alzari, P.M. | Deposit date: | 2007-04-11 | Release date: | 2007-08-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Crystal Structure of M. Leprae Ml2640C Defines a Large Family of Putative S-Adenosylmethionine- Dependent Methyltransferases in Mycobacteria. Protein Sci., 16, 2007
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2UYO
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![BU of 2uyo by Molmil](/molmil-images/mine/2uyo) | Crystal structure of ML2640c from Mycobacterium leprae in an hexagonal crystal form | Descriptor: | HYPOTHETICAL PROTEIN ML2640 | Authors: | Grana, M, Buschiazzo, A, Wehenkel, A, Haouz, A, Miras, I, Shepard, W, Alzari, P.M. | Deposit date: | 2007-04-11 | Release date: | 2007-08-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Crystal Structure of M. Leprae Ml2640C Defines a Large Family of Putative S-Adenosylmethionine- Dependent Methyltransferases in Mycobacteria. Protein Sci., 16, 2007
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1HH5
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![BU of 1hh5 by Molmil](/molmil-images/mine/1hh5) | cytochrome c7 from Desulfuromonas acetoxidans | Descriptor: | CYTOCHROME C7, HEME C | Authors: | Czjzek, M, Haser, R, Arnoux, P, Shepard, W. | Deposit date: | 2000-12-21 | Release date: | 2001-05-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of Cytochrome C7 from Desulfuromonas Acetoxidans at 1.9A Resolutio N Acta Crystallogr.,Sect.D, 57, 2001
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4PMO
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![BU of 4pmo by Molmil](/molmil-images/mine/4pmo) | Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c, monoclinic crystal form I | Descriptor: | FORMIC ACID, GLYCEROL, SODIUM ION, ... | Authors: | Bellinzoni, M, Haouz, A, Shepard, W, Alzari, P.M. | Deposit date: | 2014-05-22 | Release date: | 2014-10-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c. J.Struct.Biol., 188, 2014
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4PMQ
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![BU of 4pmq by Molmil](/molmil-images/mine/4pmq) | Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c in complex with L-tartrate (orthorhombic crystal form) | Descriptor: | GLYCEROL, L(+)-TARTARIC ACID, Tat-secreted protein Rv2525c | Authors: | Bellinzoni, M, Haouz, A, Shepard, W, Alzari, P.M. | Deposit date: | 2014-05-22 | Release date: | 2014-10-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c. J.Struct.Biol., 188, 2014
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4PMN
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![BU of 4pmn by Molmil](/molmil-images/mine/4pmn) | Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c in complex with MES (monoclinic crystal form I) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, SULFATE ION, ... | Authors: | Bellinzoni, M, Haouz, A, Shepard, W, Alzari, P.M. | Deposit date: | 2014-05-22 | Release date: | 2014-10-08 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c. J.Struct.Biol., 188, 2014
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4PMR
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![BU of 4pmr by Molmil](/molmil-images/mine/4pmr) | Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c in complex with HEPES (monoclinic crystal form II) | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SODIUM ION, Tat-secreted protein Rv2525c | Authors: | Bellinzoni, M, Haouz, A, Shepard, W, Alzari, P.M. | Deposit date: | 2014-05-22 | Release date: | 2014-10-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c. J.Struct.Biol., 188, 2014
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