5K1N

Human TTR altered by a rhenium tris-carbonyl Pyta-C12 derivative

Summary for 5K1N

Entry DOI	10.2210/pdb5k1n/pdb
Related	5K1J
Descriptor	Transthyretin, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... (8 entities in total)
Functional Keywords	large conformational change, human ttr, potentiality for scavenging beta-amyloid in alzheimer disease, transport protein
Biological source	Homo sapiens (Human)
Cellular location	Secreted: P02766
Total number of polymer chains	2
Total formula weight	26918.16
Authors	Stura, E.A.,Ciccone, L.,Shepard, W. (deposition date: 2016-05-18, release date: 2016-07-20, Last modification date: 2024-01-10)
Primary citation	Ciccone, L.,Policar, C.,Stura, E.A.,Shepard, W. Human TTR conformation altered by rhenium tris-carbonyl derivatives. J.Struct.Biol., 195:353-364, 2016 Cited by PubMed: 27402536 DOI: 10.1016/j.jsb.2016.07.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.81 Å)

Structure validation