Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005179 | molecular_function | hormone activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006144 | biological_process | purine nucleobase metabolic process |
| A | 0007165 | biological_process | signal transduction |
| A | 0035578 | cellular_component | azurophil granule lumen |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0070324 | molecular_function | thyroid hormone binding |
| B | 0005179 | molecular_function | hormone activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006144 | biological_process | purine nucleobase metabolic process |
| B | 0007165 | biological_process | signal transduction |
| B | 0035578 | cellular_component | azurophil granule lumen |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 0070324 | molecular_function | thyroid hormone binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 201 |
| Chain | Residue |
| A | ASN27 |
| A | ALA36 |
| A | GLU42 |
| A | THR49 |
| A | GLU51 |
| A | HOH318 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 202 |
| Chain | Residue |
| A | THR59 |
| A | PHE44 |
| A | LYS48 |
| A | LEU58 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue PEG A 203 |
| Chain | Residue |
| A | LYS76 |
| A | PRO86 |
| A | PHE87 |
| A | GLU89 |
| A | HOH312 |
| B | ILE68 |
| B | THR96 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue RE A 204 |
| Chain | Residue |
| A | GLU89 |
| A | HIS90 |
| A | HOH322 |
| B | VAL93 |
| B | VAL94 |
| B | HOH351 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 205 |
| Chain | Residue |
| A | ILE26 |
| A | ASN27 |
| A | GLU63 |
| A | TYR78 |
| A | HOH308 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 201 |
| Chain | Residue |
| B | PHE44 |
| B | LEU58 |
| B | THR59 |
| B | GLU63 |
| B | HOH322 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue RE B 202 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue RE B 203 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue IMD B 204 |
| Chain | Residue |
| B | ASN27 |
| B | ALA36 |
| B | ALA37 |
| B | THR49 |
| B | HOH332 |
Functional Information from PROSITE/UniProt
| site_id | PS00768 |
| Number of Residues | 16 |
| Details | TRANSTHYRETIN_1 Transthyretin signature 1. KVLDavrGsPAinVaV |
| Chain | Residue | Details |
| A | LYS15-VAL30 | |
| site_id | PS00769 |
| Number of Residues | 13 |
| Details | TRANSTHYRETIN_2 Transthyretin signature 2. YTIAalLSPYSYS |
| Chain | Residue | Details |
| A | TYR105-SER117 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LYS15 | |
| A | GLU54 | |
| A | SER117 | |
| B | LYS15 | |
| B | GLU54 | |
| B | SER117 | |
| Chain | Residue | Details |
| A | CYS10 | |
| B | CYS10 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: 4-carboxyglutamate; in a patient with Moyamoya disease => ECO:0000269|PubMed:18221012 |
| Chain | Residue | Details |
| A | GLU42 | |
| B | GLU42 | |
| Chain | Residue | Details |
| A | SER52 | |
| B | SER52 | |
| Chain | Residue | Details |
| A | ASN98 | |
| B | ASN98 | |
