8W6T
| NaS1 in IN/OUT state | Descriptor: | Solute carrier family 13 member 1 | Authors: | Chi, X, Chen, Y, Li, Y, Zhang, Y, Shen, Y, Chen, Y, Wang, Z, Yan, R. | Deposit date: | 2023-08-29 | Release date: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structures of the human NaS1 and NaDC1 transporters revealed the elevator transport and allosteric regulation mechanism. Sci Adv, 10, 2024
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8W6C
| CryoEM structure of NaDC1 with Citrate | Descriptor: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CHOLESTEROL HEMISUCCINATE, CITRIC ACID, ... | Authors: | Chi, X, Chen, Y, Li, Y, Dai, L, Zhang, Y, Shen, Y, Chen, Y, Shi, T, Yang, H, Wang, Z, Yan, R. | Deposit date: | 2023-08-28 | Release date: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structures of the human NaS1 and NaDC1 transporters revealed the elevator transport and allosteric regulation mechanism. Sci Adv, 10, 2024
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8W6H
| NaS1 with sulfate - IN/IN state | Descriptor: | CHOLESTEROL, SODIUM ION, SULFATE ION, ... | Authors: | Chi, X, Chen, Y, Li, Y, Zhang, Y, Shen, Y, Chen, Y, Wang, Z, Yan, R. | Deposit date: | 2023-08-28 | Release date: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structures of the human NaS1 and NaDC1 transporters revealed the elevator transport and allosteric regulation mechanism. Sci Adv, 10, 2024
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8W6N
| NaS1 with sulfate in IN/OUT state | Descriptor: | SODIUM ION, SULFATE ION, Solute carrier family 13 member 1 | Authors: | Chi, X, Chen, Y, Li, Y, Zhang, Y, Shen, Y, Chen, Y, Wang, Z, Yan, R. | Deposit date: | 2023-08-29 | Release date: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures of the human NaS1 and NaDC1 transporters revealed the elevator transport and allosteric regulation mechanism. Sci Adv, 10, 2024
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8W6D
| CryoEM structure of NaDC1 in apo state | Descriptor: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ... | Authors: | Chi, X, Chen, Y, Li, Y, Zhang, Y, Shen, Y, Chen, Y, Wang, Z, Yan, R. | Deposit date: | 2023-08-28 | Release date: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Cryo-EM structures of the human NaS1 and NaDC1 transporters revealed the elevator transport and allosteric regulation mechanism. Sci Adv, 10, 2024
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8W6O
| NaS1 in IN/IN state | Descriptor: | CHOLESTEROL, SODIUM ION, Solute carrier family 13 member 1 | Authors: | Chi, X, Chen, Y, Li, Y, Zhang, Y, Shen, Y, Chen, Y, Wang, Z, Yan, R. | Deposit date: | 2023-08-29 | Release date: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM structures of the human NaS1 and NaDC1 transporters revealed the elevator transport and allosteric regulation mechanism. Sci Adv, 10, 2024
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3NK6
| Structure of the Nosiheptide-resistance methyltransferase | Descriptor: | 23S rRNA methyltransferase | Authors: | Yang, H, Wang, Z, Shen, Y, Wang, P, Murchie, A, Xu, Y. | Deposit date: | 2010-06-18 | Release date: | 2010-07-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the Nosiheptide-Resistance Methyltransferase of Streptomyces actuosus Biochemistry, 49, 2010
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4Q2J
| A novel structure-based mechanism for DNA-binding of SATB1 | Descriptor: | DNA-binding protein SATB1 | Authors: | Wang, Z, Long, J, Yang, X, Shen, Y. | Deposit date: | 2014-04-08 | Release date: | 2015-03-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.603 Å) | Cite: | Crystal structure of the ubiquitin-like domain-CUT repeat-like tandem of special AT-rich sequence binding protein 1 (SATB1) reveals a coordinating DNA-binding mechanism. J.Biol.Chem., 289, 2014
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1YWY
| Solution Structure of Pseudomonas aeruginosa Protein PA2021. The Northeast Structural Genomics Consortium Target Pat85. | Descriptor: | hypothetical protein PA2021 | Authors: | Lin, Y.C, Liu, G, Shen, Y, Yee, A, Arrowsmith, C.H, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-02-18 | Release date: | 2005-04-12 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution Structure of Pseudomonas aeruginosa Protein PA2021. To be Published
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3NK7
| Structure of the Nosiheptide-resistance methyltransferase S-adenosyl-L-methionine Complex | Descriptor: | 23S rRNA methyltransferase, S-ADENOSYLMETHIONINE | Authors: | Yang, H, Wang, Z, Shen, Y, Wang, P, Murchie, A, Xu, Y. | Deposit date: | 2010-06-18 | Release date: | 2010-07-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of the Nosiheptide-Resistance Methyltransferase of Streptomyces actuosus Biochemistry, 49, 2010
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1YRU
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1YRT
| Crystal Structure analysis of the adenylyl cyclaes catalytic domain of adenylyl cyclase toxin of Bordetella pertussis in presence of c-terminal calmodulin | Descriptor: | Bifunctional hemolysin-adenylate cyclase, CALCIUM ION, Calmodulin | Authors: | Guo, Q, Shen, Y, Lee, Y.S, Gibbs, C.S, Mrksich, M, Tang, W.J. | Deposit date: | 2005-02-04 | Release date: | 2006-01-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin. Embo J., 24, 2005
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4EJS
| Structure of yeast elongator subcomplex Elp456 | Descriptor: | Elongator complex protein 4, Elongator complex protein 5, Elongator complex protein 6 | Authors: | Lin, Z, Zhao, W, Long, J, Shen, Y. | Deposit date: | 2012-04-07 | Release date: | 2012-05-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.606 Å) | Cite: | Crystal structure of elongator subcomplex Elp4-6 J.Biol.Chem., 287, 2012
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1XN8
| Solution Structure of Bacillus subtilis Protein yqbG: The Northeast Structural Genomics Consortium Target SR215 | Descriptor: | Hypothetical protein yqbG | Authors: | Liu, G, Ma, L, Shen, Y, Acton, T, Atreya, H.S, Xiao, R, Joachimiak, A, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-10-04 | Release date: | 2004-12-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR data collection and analysis protocol for high-throughput protein structure determination. Proc.Natl.Acad.Sci.Usa, 102, 2005
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1KK7
| SCALLOP MYOSIN IN THE NEAR RIGOR CONFORMATION | Descriptor: | CALCIUM ION, MAGNESIUM ION, MYOSIN ESSENTIAL LIGHT CHAIN, ... | Authors: | Himmel, D.M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, A.G, Cohen, C. | Deposit date: | 2001-12-06 | Release date: | 2002-10-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor. Proc.Natl.Acad.Sci.USA, 99, 2002
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5WZE
| The structure of Pseudomonas aeruginosa aminopeptidase PepP | Descriptor: | 1,2-ETHANEDIOL, ALANINE, Aminopeptidase P, ... | Authors: | Bao, R, Peng, C.T, Liu, L, He, L.H, Li, C.C, Li, T, Shen, Y.L, Zhu, Y.B, Song, Y.J. | Deposit date: | 2017-01-17 | Release date: | 2018-01-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.783 Å) | Cite: | Structure-Function Relationship of Aminopeptidase P from Pseudomonas aeruginosa. Front Microbiol, 8, 2017
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1ZNV
| How a His-metal finger endonuclease ColE7 binds and cleaves DNA with a transition metal ion cofactor | Descriptor: | Colicin E7, Colicin E7 immunity protein, NICKEL (II) ION, ... | Authors: | Doudeva, L.G, Huang, H, Hsia, K.C, Shi, Z, Li, C.L, Shen, Y, Yuan, H.S. | Deposit date: | 2005-05-12 | Release date: | 2006-03-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structural analysis and metal-dependent stability and activity studies of the ColE7 endonuclease domain in complex with DNA/Zn2+ or inhibitor/Ni2+ Protein Sci., 15, 2006
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5CQR
| Dimerization of Elp1 is essential for Elongator complex assembly | Descriptor: | Elongator complex protein 1 | Authors: | Lin, Z, Xu, H, Li, F, Diao, W, Long, J, Shen, Y. | Deposit date: | 2015-07-22 | Release date: | 2015-08-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.015 Å) | Cite: | Dimerization of elongator protein 1 is essential for Elongator complex assembly. Proc.Natl.Acad.Sci.USA, 112, 2015
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4R3Q
| Crystal structure of SYCE3 | Descriptor: | Synaptonemal complex central element protein 3 | Authors: | Lu, J, Feng, J, Zhou, W, Yang, X, Shen, Y. | Deposit date: | 2014-08-17 | Release date: | 2014-11-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Structural insight into the central element assembly of the synaptonemal complex Sci Rep, 4, 2014
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4NSC
| Crystal Structure of CBARA1 in the Apo-form | Descriptor: | Calcium uptake protein 1, mitochondrial | Authors: | Wang, L, Yang, X, Li, S, Shen, Y. | Deposit date: | 2013-11-28 | Release date: | 2014-02-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake. Embo J., 33, 2014
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1ZNS
| Crystal structure of N-ColE7/12-bp DNA/Zn complex | Descriptor: | 5'-D(*CP*GP*GP*GP*AP*TP*AP*TP*CP*CP*CP*G)-3', Colicin E7, ZINC ION | Authors: | Doudeva, L.G, Huang, H, Hsia, K.C, Shi, Z, Li, C.L, Shen, Y, Yuan, H.S. | Deposit date: | 2005-05-12 | Release date: | 2006-03-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structural analysis and metal-dependent stability and activity studies of the ColE7 endonuclease domain in complex with DNA/Zn2+ or inhibitor/Ni2+ Protein Sci., 15, 2006
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1XPV
| Solution Structure of Northeast Structural Genomics Target Protein XcR50 from X. Campestris | Descriptor: | hypothetical protein XCC2852 | Authors: | Shao, Y, Acton, T.B, Liu, G, Ma, L, Shen, Y, Xiao, R, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-10-09 | Release date: | 2004-12-14 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution Structure of Northeast Structural Genomics Target Protein XcR50 from X. Campestris To be Published
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3PFN
| Crystal Structure of human NAD kinase | Descriptor: | NAD kinase, UNKNOWN ATOM OR ION | Authors: | Wang, H, Tempel, W, Wernimont, A.K, Tong, Y, Guan, X, Shen, Y, Li, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-10-28 | Release date: | 2010-11-10 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of human NAD kinase to be published
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1SK6
| Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin, 3',5' cyclic AMP (cAMP), and pyrophosphate | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CALCIUM ION, Calmodulin, ... | Authors: | Guo, Q, Shen, Y, Zhukovskaya, N.L, Tang, W.J. | Deposit date: | 2004-03-04 | Release date: | 2004-06-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and pyrophosphate. J.Biol.Chem., 279, 2004
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8WWW
| Crystal structure of the adenylation domain of SyAstC | Descriptor: | Carrier domain-containing protein, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Li, Z, Zhu, Z, Zhu, D, Shen, Y. | Deposit date: | 2023-10-27 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Functional Application of the Single-Module NRPS-like d-Alanyltransferase in Maytansinol Biosynthesis Acs Catalysis, 14, 2024
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