1CTA
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1PON
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2F09
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2JPF
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1CTD
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9C5E
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![BU of 9c5e by Molmil](/molmil-images/mine/9c5e) | Covalent Complex Between Parkin Catalytic (Rcat) Domain and Ubiquitin | Descriptor: | 1.7.6 3-bromanylpropan-1-amine, E3 ubiquitin-protein ligase parkin, Ubiquitin, ... | Authors: | Connelly, E.M, Rintala-Dempsey, A.C, Gundogdu, M, Freeman, E.A, Koszela, J, Aguirre, J.D, Zhu, G, Kamarainen, O, Tadayon, R, Walden, H, Shaw, G.S. | Deposit date: | 2024-06-06 | Release date: | 2024-08-14 | Method: | SOLUTION NMR | Cite: | Capturing the catalytic intermediates of parkin ubiquitination. Proc.Natl.Acad.Sci.USA, 121, 2024
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1MQ1
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![BU of 1mq1 by Molmil](/molmil-images/mine/1mq1) | Ca2+-S100B-TRTK-12 complex | Descriptor: | F-actin capping protein alpha-1 subunit, S-100 protein, beta chain | Authors: | McClintock, K.A, Shaw, G.S. | Deposit date: | 2002-09-13 | Release date: | 2002-12-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A novel S100 target conformation is revealed by the solution structure of the Ca2+-S100B-TRTK-12 complex. J.Biol.Chem., 278, 2003
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6N13
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![BU of 6n13 by Molmil](/molmil-images/mine/6n13) | UbcH7-Ub Complex with R0RBR Parkin and phosphoubiquitin | Descriptor: | E3 ubiquitin-protein ligase parkin, Ubiquitin-conjugating enzyme E2 L3, ZINC ION, ... | Authors: | Condos, T.E.C, Dunkerley, K.M, Freeman, E.A, Barber, K.R, Aguirre, J.D, Chaugule, V.K, Xiao, Y, Konermann, L, Walden, H, Shaw, G.S. | Deposit date: | 2018-11-08 | Release date: | 2018-11-28 | Last modified: | 2020-01-08 | Method: | SOLUTION NMR | Cite: | Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation. EMBO J., 37, 2018
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7K6B
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7KRB
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7JOF
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![BU of 7jof by Molmil](/molmil-images/mine/7jof) | Calcium-bound C2A Domain from Human Dysferlin | Descriptor: | CALCIUM ION, Isoform 6 of Dysferlin | Authors: | Tadayon, R, Wang, Y, Santamaria, L, Mercier, P, Forristal, C, Shaw, G.S. | Deposit date: | 2020-08-06 | Release date: | 2021-06-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner. Biochem.J., 478, 2021
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5C1Z
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![BU of 5c1z by Molmil](/molmil-images/mine/5c1z) | Parkin (UblR0RBR) | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... | Authors: | kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H. | Deposit date: | 2015-06-15 | Release date: | 2015-07-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis. Embo J., 34, 2015
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5C23
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![BU of 5c23 by Molmil](/molmil-images/mine/5c23) | Parkin (S65DUblR0RBR) | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... | Authors: | Kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H. | Deposit date: | 2015-06-15 | Release date: | 2015-07-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis. Embo J., 34, 2015
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2ASY
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![BU of 2asy by Molmil](/molmil-images/mine/2asy) | Solution Structure of ydhR protein from Escherichia coli | Descriptor: | Protein ydhR precursor | Authors: | Revington, M, Semesi, A, Yee, A, Shaw, G.S, Ontario Centre for Structural Proteomics (OCSP) | Deposit date: | 2005-08-24 | Release date: | 2005-11-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the Escherichia coli protein ydhR: A putative mono-oxygenase. Protein Sci., 14, 2005
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4DRW
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![BU of 4drw by Molmil](/molmil-images/mine/4drw) | Crystal Structure of the Ternary Complex between S100A10, an Annexin A2 N-terminal Peptide and an AHNAK Peptide | Descriptor: | Neuroblast differentiation-associated protein AHNAK, Protein S100-A10/Annexin A2 chimeric protein | Authors: | Rezvanpour, A, Lee, T.-W, Junop, M.S, Shaw, G.S. | Deposit date: | 2012-02-17 | Release date: | 2012-10-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure of an asymmetric ternary protein complex provides insight for membrane interaction. Structure, 20, 2012
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1NSH
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2JMO
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![BU of 2jmo by Molmil](/molmil-images/mine/2jmo) | IBR domain of Human Parkin | Descriptor: | Parkin, ZINC ION | Authors: | Beasley, S.A, Hristova, V.A, Shaw, G.S. | Deposit date: | 2006-11-24 | Release date: | 2007-02-27 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Structure of the Parkin in-between-ring domain provides insights for E3-ligase dysfunction in autosomal recessive Parkinson's disease. Proc.Natl.Acad.Sci.USA, 104, 2007
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2KJH
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1UWO
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2LGY
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![BU of 2lgy by Molmil](/molmil-images/mine/2lgy) | Ubiquitin-like domain from HOIL-1 | Descriptor: | RanBP-type and C3HC4-type zinc finger-containing protein 1 | Authors: | Beasley, S.A, Shaw, G.S. | Deposit date: | 2011-08-03 | Release date: | 2012-06-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the E3 ligase HOIL-1 Ubl domain. Protein Sci., 21, 2012
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2LGV
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![BU of 2lgv by Molmil](/molmil-images/mine/2lgv) | Rbx1 | Descriptor: | E3 ubiquitin-protein ligase RBX1, ZINC ION | Authors: | Spratt, D.E, Shaw, G.S. | Deposit date: | 2011-08-02 | Release date: | 2012-03-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Selective recruitment of an e2~ubiquitin complex by an e3 ubiquitin ligase. J.Biol.Chem., 287, 2012
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2M48
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![BU of 2m48 by Molmil](/molmil-images/mine/2m48) | Solution Structure of IBR-RING2 Tandem Domain from Parkin | Descriptor: | E3 UBIQUITIN-PROTEIN LIGASE PARKIN, ZINC ION | Authors: | Noh, Y.J, Mercier, P, Spratt, D.E, Shaw, G.S. | Deposit date: | 2013-01-30 | Release date: | 2013-05-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A molecular explanation for the recessive nature of parkin-linked Parkinson's disease. Nat Commun, 4, 2013
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2LWR
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![BU of 2lwr by Molmil](/molmil-images/mine/2lwr) | Solution Structure of RING2 Domain from Parkin | Descriptor: | SD01679p, ZINC ION | Authors: | Mercier, P, Spratt, D.E, Manczyk, N, Shaw, G.S. | Deposit date: | 2012-08-06 | Release date: | 2013-06-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A molecular explanation for the recessive nature of parkin-linked Parkinson's disease. Nat Commun, 4, 2013
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2M9Y
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2PRU
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![BU of 2pru by Molmil](/molmil-images/mine/2pru) | NMR Structure of Human apoS100B at 10C | Descriptor: | Protein S100-B | Authors: | Malik, S, Shaw, G.S, Revington, M. | Deposit date: | 2007-05-04 | Release date: | 2008-04-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Analysis of the structure of human apo-S100B at low temperature indicates a unimodal conformational distribution is adopted by calcium-free S100 proteins. Proteins, 73, 2008
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