6UVC
 
 | | Crystal structure of BCL-XL bound to compound 8: (R)-3-(Benzylthio)-2-(3-(2-((4'-chloro-[1,1'-biphenyl]-2-yl)methyl)-1,2,3,4-tetrahydroisoquinoline-6-carbonyl)-3-(4-methylbenzyl)ureido)propanoic acid | | Descriptor: | (R)-3-(Benzylthio)-2-(3-(2-((4'-chloro-[1,1'-biphenyl]-2-yl)methyl)-1,2,3,4-tetrahydroisoquinoline-6-carbonyl)-3-(4-methylbenzyl)ureido)propanoic acid, 1,2-ETHANEDIOL, Bcl-2-like protein 1, ... | | Authors: | Roy, M.J, Birkinshaw, R, Lessene, G, Czabotar, P.E. | | Deposit date: | 2019-11-02 | | Release date: | 2021-05-05 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-X L and BCL-2.
J.Med.Chem., 64, 2021
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6UVD
 | | Crystal structure of BCL-XL bound to compound 2: (2R)-3-(Benzylsulfanyl)-2-({[(4-methylphenyl)methyl] [(4 phenylphenyl)carbonyl] carbamoyl}amino) propanoic acid | | Descriptor: | (2R)-3-(Benzylsulfanyl)-2-({[(4-methylphenyl)methyl] [(4 phenylphenyl)carbonyl] carbamoyl}amino) propanoic acid, 1,2-ETHANEDIOL, Bcl-2-like protein 1, ... | | Authors: | Roy, M.J, Birkinshaw, R, Lessene, G, Czabotar, P.E. | | Deposit date: | 2019-11-02 | | Release date: | 2021-05-05 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-X L and BCL-2.
J.Med.Chem., 64, 2021
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3FBK
 | | Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A | | Descriptor: | Regulator of G-protein signaling 3, SULFATE ION | | Authors: | Forouhar, F, Lew, S, Seetharaman, J, Mao, L, Xiao, R, Ciccosanti, C, Foote, E.L, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-11-19 | | Release date: | 2008-12-02 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A
To be Published
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1T5Y
 | | Crystal Structure of Northeast Structural Genomics Consortium Target HR2118: A Human Homolog of Saccharomyces cerevisiae Nip7p | | Descriptor: | SACCHAROMYCES CEREVISIAE Nip7p HOMOLOG | | Authors: | Kuzin, A.P, Chen, Y, Forouhar, F, Acton, T.B, Shastry, R, Ma, L.-C, Cooper, B, Xiao, R, Montelione, G, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2004-05-05 | | Release date: | 2004-06-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of Northeast Structural Genomics Consortium Target HR2118:
A Human Homolog of Saccharomyces cerevisiae Nip7p
To be Published
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1TO0
 | | X-ray structure of Northeast Structural Genomics target protein sr145 from Bacillus subtilis | | Descriptor: | Hypothetical UPF0247 protein yyda | | Authors: | Kuzin, A.P, Edstrom, W, Vorobiev, S.M, Shastry, R, Ma, L.-C, Xiao, R, Acton, T, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2004-06-11 | | Release date: | 2004-07-20 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | X-ray structure of Northeast Structural Genomics target protein sr145 from Bacillus subtilis
To be Published
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1TZA
 | | X-ray structure of Northeast Structural Genomics Consortium target SoR45 | | Descriptor: | CACODYLATE ION, apaG protein | | Authors: | Kuzin, A.P, Vorobiev, S.M, Edstrom, W, Acton, T.B, Shastry, R, Ma, L.-C, Cooper, B, Xiao, R, Montelione, G, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2004-07-09 | | Release date: | 2004-07-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | X-ray structure of Northeast Structural Genomics Consortium
target SoR45
To be Published
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1TWD
 | | Crystal Structure of the Putative Copper Homeostasis Protein (CutC) from Shigella flexneri, Northeast Structural Genomics Target SfR33 | | Descriptor: | Copper homeostasis protein cutC | | Authors: | Forouhar, F, Lee, I, Vorobiev, S.M, Ma, L.-C, Shastry, R, Conover, K, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2004-06-30 | | Release date: | 2004-07-20 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal Structure of the Putative Copper Homeostasis Protein (CutC) from Shigella flexneri, Northeast Structural Genomics Target SfR33
To be Published
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1TZ9
 | | Crystal Structure of the Putative Mannonate Dehydratase from Enterococcus faecalis, Northeast Structural Genomics Target EfR41 | | Descriptor: | Mannonate dehydratase | | Authors: | Forouhar, F, Chen, Y, Xiao, R, Cooper, B, Shastry, R, Acton, T.A, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2004-07-09 | | Release date: | 2004-07-20 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal Structure of the Putative Mannonate Dehydratase from Enterococcus faecalis, Northeast Structural Genomics Target EfR41
To be Published
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6AVK
 | | Streptavidin bound to peptide-like compound KPM-6 | | Descriptor: | 1-hydroxydodecan-4-one, N-[(2H-1,3-benzodioxol-5-yl)methyl]-2-({[(2H-1,3-benzodioxol-5-yl)methyl][2-(chloromethyl)-1,3-oxazole-4-carbonyl]amino}methyl)-N-[(4-carbamoyl-1,3-oxazol-2-yl)methyl]-1,3-oxazole-4-carboxamide, Streptavidin | | Authors: | Park, H, Shamim, R, McEnaney, P, Kodadek, T. | | Deposit date: | 2017-09-02 | | Release date: | 2018-08-08 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Efficient Workflow for Screening DNA-encoded One Bead One Compound Libraries Using a Flow Cytometer
To be Published
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1SQR
 | | Solution Structure of the 50S Ribosomal Protein L35AE from Pyrococcus furiosus. Northeast Structural Genomics Consortium Target PfR48. | | Descriptor: | 50S ribosomal protein L35Ae | | Authors: | Snyder, D.A, Aramini, J.M, Huang, Y.J, Xiao, R, Cort, J.R, Shastry, R, Ma, L.C, Liu, J, Rost, B, Acton, T.B, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2004-03-19 | | Release date: | 2004-11-16 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the 50S Ribosomal Protein L35AE from Pyrococcus furiosus: Northeast Structural Genomics Consortium Target PfR48
To be Published
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1T3H
 | | X-ray Structure of Dephospho-CoA Kinase from E. coli Norteast Structural Genomics Consortium Target ER57 | | Descriptor: | Dephospho-CoA kinase, SULFATE ION | | Authors: | Kuzin, A.P, Chen, Y, Forouhar, F, Edstrom, W, Benach, J, Vorobiev, S, Acton, T, Shastry, R, Ma, L.-C, Xia, R, Montelione, G, Tong, L, Hunt, J, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2004-04-26 | | Release date: | 2004-05-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | X-ray Structure of Dephospho-CoA Kinase from E. coli
Norteast Structural Genomics Consortium Target ER57
TO BE PUBLISHED
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1R9P
 | | Solution NMR Structure Of The Haemophilus Influenzae Iron-Sulfur Cluster Assembly Protein U (IscU) with Zinc Bound at the Active Site. Northeast Structural Genomics Consortium Target IR24. | | Descriptor: | NifU-like protein, ZINC ION | | Authors: | Ramelot, T.A, Cort, J.R, Xiao, R, Shastry, R, Acton, T.B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2003-10-30 | | Release date: | 2004-11-09 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of the iron-sulfur cluster assembly protein U (IscU) with zinc bound at the active site.
J.Mol.Biol., 344, 2004
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3FB2
 | | Crystal structure of the human brain alpha spectrin repeats 15 and 16. Northeast Structural Genomics Consortium target HR5563a. | | Descriptor: | Spectrin alpha chain, brain spectrin | | Authors: | Vorobiev, S.M, Su, M, Seetharaman, J, Shastry, R, Foote, E.L, Ciccosanti, C, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-11-18 | | Release date: | 2008-11-25 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the human brain alpha spectrin repeats 15 and 16.
To be Published
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3EXA
 | | Crystal structure of the full-length tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans, Northeast Structural Genomics Consortium target BhR41. | | Descriptor: | tRNA delta(2)-isopentenylpyrophosphate transferase | | Authors: | Forouhar, F, Abashidze, M, Neely, H, Seetharaman, J, Shastry, R, Janjua, H, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-10-16 | | Release date: | 2008-11-11 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the full-length tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans, Northeast Structural Genomics Consortium target BhR41.
To be Published
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3CER
 | | Crystal structure of the exopolyphosphatase-like protein Q8G5J2. Northeast Structural Genomics Consortium target BlR13 | | Descriptor: | Possible exopolyphosphatase-like protein, SULFATE ION | | Authors: | Kuzin, A.P, Su, M, Chen, Y, Neely, H, Seetharaman, J, Shastry, R, Fang, Y, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-02-29 | | Release date: | 2008-04-01 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the exopolyphosphatase-like protein Q8G5J2. Northeast Structural Genomics Consortium target BlR13.
To be Published
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3GQQ
 | | Crystal structure of the human retinal protein 4 (unc-119 homolog A). Northeast Structural Genomics Consortium target HR3066a | | Descriptor: | Protein unc-119 homolog A, UNKNOWN LIGAND | | Authors: | Vorobiev, S.M, Chen, Y, Seetharaman, J, Shastry, R, Foote, E.L, Ciccosanti, C, Sahdev, S, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-03-24 | | Release date: | 2009-04-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.945 Å) | | Cite: | Crystal structure of the human retinal protein 4 (unc-119 homolog A).
To be Published
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2W29
 | | Gly102Thr mutant of Rv3291c | | Descriptor: | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN | | Authors: | Shrivastava, T, Dey, S, Ravishankar, R. | | Deposit date: | 2008-10-25 | | Release date: | 2009-11-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (4.1 Å) | | Cite: | Ligand-Induced Structural Transitions, Mutational Analysis, and 'Open' Quaternary Structure of the M. Tuberculosis Feast/Famine Regulatory Protein (Rv3291C).
J.Mol.Biol., 392, 2009
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2BEX
 | | Crystal structure of Placental Ribonuclease Inhibitor in complex with Human Eosinophil Derived Neurotoxin at 2A resolution | | Descriptor: | ALPHA-KETOMALONIC ACID, GLYCEROL, NONSECRETORY RIBONUCLEASE, ... | | Authors: | Iyer, S, Holloway, D.E, Kumar, K, Shapiro, R, Acharya, K.R. | | Deposit date: | 2004-12-01 | | Release date: | 2005-03-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Molecular Recognition of Human Eosinophil-Derived Neurotoxin (Rnase 2) by Placental Ribonuclease Inhibitor
J.Mol.Biol., 347, 2005
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1ERP
 | | NUCLEAR MAGNETIC RESONANCE SOLUTION STRUCTURE OF THE PHEROMONE ER-10 FROM THE CILIATED PROTOZOAN EUPLOTES RAIKOVI | | Descriptor: | PHEROMONE ER-10 | | Authors: | Brown, L.R, Mronga, S, Bradshaw, R, Ortenzi, C, Luporini, P, Wuthrich, K. | | Deposit date: | 1992-12-02 | | Release date: | 1993-10-31 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | Nuclear magnetic resonance solution structure of the pheromone Er-10 from the ciliated protozoan Euplotes raikovi.
J.Mol.Biol., 231, 1993
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4GH4
 | | Crystal Structure of Foot and Mouth Disease Virus A22 Serotype | | Descriptor: | capsid protein VP1, capsid protein VP2, capsid protein VP3, ... | | Authors: | Kotecha, A, Jinshan, R, Curry, S, Fry, E, Stuart, D. | | Deposit date: | 2012-08-07 | | Release date: | 2013-02-20 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Perturbations in the surface structure of A22 Iraq foot-and-mouth disease virus accompanying coupled changes in host cell specificity and antigenicity.
Structure, 4, 1996
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5UAE
 | | Crystal structure of the coiled-coil domain from Listeria Innocua Phage Integrase (Trigonal Form) | | Descriptor: | CITRATE ANION, Putative integrase | | Authors: | Gupta, K, Sharp, R, Yuan, J.B, Van Duyne, G.D. | | Deposit date: | 2016-12-19 | | Release date: | 2017-05-24 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Coiled-coil interactions mediate serine integrase directionality.
Nucleic Acids Res., 45, 2017
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5UDO
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5U96
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2EPE
 | | Crystal structure analysis of Hen egg white lysozyme grown by capillary method | | Descriptor: | Lysozyme C | | Authors: | Naresh, M.D, Subramanian, V, Jaimohan, S.M, Rajaram, A, Arumugam, V, Usha, R, Mandal, A.B. | | Deposit date: | 2007-03-29 | | Release date: | 2007-04-17 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure analysis of Hen egg white lysozyme grown by capillary method
To be published
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7CFE
 | | Crystal structure of RsmG methyltransferase of M. tuberculosis | | Descriptor: | ISOPROPYL ALCOHOL, PHOSPHATE ION, Ribosomal RNA small subunit methyltransferase G, ... | | Authors: | Bijpuria, S, Maurya, A, Kumar, P, Sharma, R, Taneja, B. | | Deposit date: | 2020-06-25 | | Release date: | 2021-06-30 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Crystal structure of RsmG methyltransferase of M. tuberculosis
To Be Published
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