1OVD
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![BU of 1ovd by Molmil](/molmil-images/mine/1ovd) | THE K136E MUTANT OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE A IN COMPLEX WITH OROTATE | 分子名称: | DIHYDROOROTATE DEHYDROGENASE A, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | 著者 | Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S. | 登録日 | 2003-03-26 | 公開日 | 2003-08-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function. J.Biol.Chem., 278, 2003
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1Y93
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![BU of 1y93 by Molmil](/molmil-images/mine/1y93) | Crystal structure of the catalytic domain of human MMP12 complexed with acetohydroxamic acid at atomic resolution | 分子名称: | ACETOHYDROXAMIC ACID, CALCIUM ION, Macrophage metalloelastase, ... | 著者 | Bertini, I, Calderone, V, Cosenza, M, Fragai, M, Lee, Y.-M, Luchinat, C, Mangani, S, Terni, B, Turano, P. | 登録日 | 2004-12-14 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | 主引用文献 | Conformational variability of matrix metalloproteinases: Beyond a single 3D structure Proc.Natl.Acad.Sci.Usa, 102, 2005
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1S88
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![BU of 1s88 by Molmil](/molmil-images/mine/1s88) | NMR structure of a DNA duplex with two INA nucleotides inserted opposite each other, dCTCAACXCAAGCT:dAGCTTGXGTTGAG | 分子名称: | 5'-D(*AP*GP*CP*TP*TP*GP*(2DM)P*GP*TP*TP*GP*AP*G)-3', 5'-D(*CP*TP*CP*AP*AP*CP*(2DM)P*CP*AP*AP*GP*CP*T)-3' | 著者 | Nielsen, C.B, Petersen, M, Pedersen, E.B, Hansen, P.E, Christensen, U.B. | 登録日 | 2004-01-31 | 公開日 | 2004-05-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure determination of a modified DNA oligonucleotide containing a new intercalating nucleic acid. Bioconjug.Chem., 15, 2004
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3Q2S
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![BU of 3q2s by Molmil](/molmil-images/mine/3q2s) | Crystal Structure of CFIm68 RRM/CFIm25 complex | 分子名称: | Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6 | 著者 | Yang, Q, Coseno, M, Gilmartin, G.M, Doublie, S. | 登録日 | 2010-12-20 | 公開日 | 2011-02-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structure of a Human Cleavage Factor CFI(m)25/CFI(m)68/RNA Complex Provides an Insight into Poly(A) Site Recognition and RNA Looping. Structure, 19, 2011
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3B7S
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![BU of 3b7s by Molmil](/molmil-images/mine/3b7s) | [E296Q]LTA4H in complex with RSR substrate | 分子名称: | ACETIC ACID, GLYCEROL, Leukotriene A-4 hydrolase, ... | 著者 | Tholander, F, Haeggstrom, J, Thunnissen, M, Muroya, A, Roques, B.-P, Fournie-Zaluski, M.-C. | 登録日 | 2007-10-31 | 公開日 | 2008-09-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.465 Å) | 主引用文献 | Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design. Chem.Biol., 15, 2008
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3B7U
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![BU of 3b7u by Molmil](/molmil-images/mine/3b7u) | Leukotriene A4 Hydrolase Complexed with KELatorphan | 分子名称: | ACETIC ACID, IMIDAZOLE, Leukotriene A-4 hydrolase, ... | 著者 | Tholander, F, Haeggstrom, J, Thunnissen, M, Muroya, A, Roques, B.-P, Fournie-Zaluski, M.-C. | 登録日 | 2007-10-31 | 公開日 | 2008-09-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design. Chem.Biol., 15, 2008
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3B7R
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![BU of 3b7r by Molmil](/molmil-images/mine/3b7r) | Leukotriene A4 Hydrolase Complexed with Inhibitor RB3040 | 分子名称: | IMIDAZOLE, Leukotriene A-4 hydrolase, N-[3-[(1-AMINOETHYL)(HYDROXY)PHOSPHORYL]-2-(1,1'-BIPHENYL-4-YLMETHYL)PROPANOYL]ALANINE, ... | 著者 | Tholander, F, Haeggstrom, J, Thunnissen, M, Muroya, A, Roques, B.-P, Fournie-Zaluski, M.-C. | 登録日 | 2007-10-31 | 公開日 | 2008-09-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.811 Å) | 主引用文献 | Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design. Chem.Biol., 15, 2008
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1Z3J
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![BU of 1z3j by Molmil](/molmil-images/mine/1z3j) | Solution Structure of MMP12 in the presence of N-isobutyl-N-4-methoxyphenylsulfonyl]glycyl hydroxamic acid (NNGH) | 分子名称: | CALCIUM ION, Macrophage metalloelastase, N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID, ... | 著者 | Bertini, I, Calderone, V, Cosenza, M, Fragai, M, Lee, Y.M, Luchinat, C, Mangani, S, Terni, B, Turano, P. | 登録日 | 2005-03-13 | 公開日 | 2005-04-19 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformational variability of matrix metalloproteinases: Beyond a single 3D structure. Proc.Natl.Acad.Sci.Usa, 102, 2005
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1YUO
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![BU of 1yuo by Molmil](/molmil-images/mine/1yuo) | Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA N-glycosylase (UNG)from atlantic cod (Gadus morhua) | 分子名称: | Uracil-DNA glycosylase | 著者 | Moe, E, Leiros, I, Riise, E.K, Olufsen, M, Lanes, O, Smalas, A.O, Willassen, N.P. | 登録日 | 2005-02-14 | 公開日 | 2005-03-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua) J.Mol.Biol., 343, 2004
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3B7T
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![BU of 3b7t by Molmil](/molmil-images/mine/3b7t) | [E296Q]LTA4H in complex with Arg-Ala-Arg substrate | 分子名称: | IMIDAZOLE, Leukotriene A-4 hydrolase, RAR peptide, ... | 著者 | Tholander, F, Haeggstrom, J, Thunnissen, M, Muroya, A, Roques, B.-P, Fournie-Zaluski, M.-C. | 登録日 | 2007-10-31 | 公開日 | 2008-09-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design. Chem.Biol., 15, 2008
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4AXP
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![BU of 4axp by Molmil](/molmil-images/mine/4axp) | NMR structure of Hsp12, a protein induced by and required for dietary restriction-induced lifespan extension in yeast. | 分子名称: | 12 KDA HEAT SHOCK PROTEIN | 著者 | Herbert, A.P, Riesen, M, Bloxam, L, Kosmidou, E, Wareing, B.M, Johnson, J.R, Phelan, M.M, Pennington, S.R, Lian, L.Y, Morgan, A. | 登録日 | 2012-06-13 | 公開日 | 2012-08-08 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure of Hsp12, a Protein Induced by and Required for Dietary Restriction-Induced Lifespan Extension in Yeast. Plos One, 7, 2012
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1YCM
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![BU of 1ycm by Molmil](/molmil-images/mine/1ycm) | Solution Structure of matrix metalloproteinase 12 (MMP12) in the presence of N-Isobutyl-N-[4-methoxyphenylsulfonyl]glycyl hydroxamic acid (NNGH) | 分子名称: | CALCIUM ION, Macrophage metalloelastase, N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID, ... | 著者 | Bertini, I, Calderone, V, Cosenza, M, Fragai, M, Lee, Y.M, Luchinat, C, Mangani, S, Terni, B, Turano, P, Structural Proteomics in Europe (SPINE) | 登録日 | 2004-12-22 | 公開日 | 2005-04-19 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformational variability of matrix metalloproteinases: Beyond a single 3D structure. Proc.Natl.Acad.Sci.Usa, 102, 2005
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4BAA
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![BU of 4baa by Molmil](/molmil-images/mine/4baa) | Redesign of a Phenylalanine Aminomutase into a beta-Phenylalanine Ammonia Lyase | 分子名称: | PHENYLALANINE AMMONIA-LYASE | 著者 | Bartsch, S, Wybenga, G.G, Jansen, M, Heberling, M.M, Wu, B, Dijkstra, B.W, Janssen, D.B. | 登録日 | 2012-09-12 | 公開日 | 2013-01-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Redesign of a Phenylalanine Aminomutase Into a Phenylalanine Ammonia Lyase To be Published
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2E50
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![BU of 2e50 by Molmil](/molmil-images/mine/2e50) | Crystal structure of SET/TAF-1beta/INHAT | 分子名称: | Protein SET, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | 著者 | Muto, S, Senda, M, Senda, T, Horikoshi, M. | 登録日 | 2006-12-18 | 公開日 | 2007-02-20 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Relationship between the structure of SET/TAF-Ibeta/INHAT and its histone chaperone activity Proc.Natl.Acad.Sci.Usa, 104, 2007
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4HWK
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![BU of 4hwk by Molmil](/molmil-images/mine/4hwk) | Crystal structure of human sepiapterin reductase in complex with sulfapyridine | 分子名称: | 4-amino-N-(pyridin-2-yl)benzenesulfonamide, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Groenlund Pedersen, M, Pojer, F, Johnsson, K. | 登録日 | 2012-11-08 | 公開日 | 2013-06-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Tetrahydrobiopterin biosynthesis as an off-target of sulfa drugs. Science, 340, 2013
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2P05
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![BU of 2p05 by Molmil](/molmil-images/mine/2p05) | Structural Insights into the Evolution of a Non-Biological Protein | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... | 著者 | Smith, M, Rosenow, M, Wang, M, Allen, J.P, Szostak, J.W, Chaput, J.C. | 登録日 | 2007-02-28 | 公開日 | 2007-06-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization. PLoS ONE, 2, 2007
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2GR2
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![BU of 2gr2 by Molmil](/molmil-images/mine/2gr2) | |
2GQW
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![BU of 2gqw by Molmil](/molmil-images/mine/2gqw) | |
2GR0
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![BU of 2gr0 by Molmil](/molmil-images/mine/2gr0) | |
2GR3
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![BU of 2gr3 by Molmil](/molmil-images/mine/2gr3) | |
2GR1
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![BU of 2gr1 by Molmil](/molmil-images/mine/2gr1) | |
2P09
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![BU of 2p09 by Molmil](/molmil-images/mine/2p09) | Structural Insights into the Evolution of a Non-Biological Protein | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... | 著者 | Smith, M, Rosenow, M, Wang, M, Allen, J.P, Szostak, J.W, Chaput, J.C. | 登録日 | 2007-02-28 | 公開日 | 2007-06-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization. PLoS ONE, 2, 2007
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4J7U
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![BU of 4j7u by Molmil](/molmil-images/mine/4j7u) | Crystal structure of human sepiapterin reductase in complex with sulfathiazole | 分子名称: | 4-amino-N-(1,3-thiazol-2-yl)benzenesulfonamide, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Groenlund Pedersen, M, Pojer, F, Johnsson, K. | 登録日 | 2013-02-14 | 公開日 | 2013-06-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Tetrahydrobiopterin biosynthesis as an off-target of sulfa drugs. Science, 340, 2013
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1W86
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![BU of 1w86 by Molmil](/molmil-images/mine/1w86) | |
1EK4
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![BU of 1ek4 by Molmil](/molmil-images/mine/1ek4) | BETA-KETOACYL [ACYL CARRIER PROTEIN] SYNTHASE I IN COMPLEX WITH DODECANOIC ACID TO 1.85 RESOLUTION | 分子名称: | BETA-KETOACYL [ACYL CARRIER PROTEIN] SYNTHASE I, LAURIC ACID | 著者 | Olsen, J.G, Kadziola, A, Siggaard-Andersen, M, von Wettstein-Knowles, P, Larsen, S. | 登録日 | 2000-03-06 | 公開日 | 2001-04-11 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structures of beta-ketoacyl-acyl carrier protein synthase I complexed with fatty acids elucidate its catalytic machinery. Structure, 9, 2001
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