2RCS
 
 | | IMMUNOGLOBULIN 48G7 GERMLINE FAB-AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY | | 分子名称: | IMMUNOGLOBULIN 48G7 GERMLINE FAB | | 著者 | Wedemayer, G.J, Wang, L.H, Patten, P.A, Schultz, P.G, Stevens, R.C. | | 登録日 | 1997-05-14 | | 公開日 | 1997-11-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural insights into the evolution of an antibody combining site.
Science, 276, 1997
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2QMI
 | | Structure of the octameric penicillin-binding protein homologue from Pyrococcus abyssi | | 分子名称: | 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, LUTETIUM (III) ION, Pbp related beta-lactamase | | 著者 | Delfosse, V, Girard, E, Moulinier, L, Schultz, P, Mayer, C. | | 登録日 | 2007-07-16 | | 公開日 | 2008-07-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the archaeal pab87 peptidase reveals a novel self-compartmentalizing protease family
Plos One, 4, 2009
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3QE4
 | | An evolved aminoacyl-tRNA Synthetase with atypical polysubstrate specificity | | 分子名称: | 4-cyano-L-phenylalanine, Tyrosyl-tRNA synthetase | | 著者 | Young, D.D, Young, T.S, Jahnz, M, Ahmad, I, Spraggon, G, Schultz, P.G. | | 登録日 | 2011-01-19 | | 公開日 | 2011-02-16 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | An Evolved Aminoacyl-tRNA Synthetase with Atypical Polysubstrate Specificity .
Biochemistry, 50, 2011
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4ZJ3
 | | Crystal structure of cephalexin bound acyl-enzyme intermediate of Val216AcrF mutant TEM1 beta-lactamase from Escherichia coli: E166N and V216AcrF mutant. | | 分子名称: | Beta-lactamase TEM | | 著者 | Xiao, H, Nasertorabi, F, Choi, S, Han, G.W, Reed, S.A, Stevens, R.C, Schultz, P.G. | | 登録日 | 2015-04-29 | | 公開日 | 2015-05-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Exploring the potential impact of an expanded genetic code on protein function.
Proc.Natl.Acad.Sci.USA, 112, 2015
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1HKL
 | | FREE AND LIGANDED FORM OF AN ESTEROLYTIC CATALYTIC ANTIBODY | | 分子名称: | 48G7 FAB | | 著者 | Wedemayer, G.J, Wang, L.H, Patten, P.A, Schultz, P.G, Stevens, R.C. | | 登録日 | 1996-12-20 | | 公開日 | 1997-03-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Crystal structures of the free and liganded form of an esterolytic catalytic antibody.
J.Mol.Biol., 268, 1997
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1A4K
 | | DIELS ALDER CATALYTIC ANTIBODY WITH TRANSITION STATE ANALOGUE | | 分子名称: | ANTIBODY FAB, CADMIUM ION, [4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID | | 著者 | Spiller, B.W, Romesburg, F.E, Schultz, P.G, Stevens, R.C. | | 登録日 | 1998-01-30 | | 公開日 | 1998-05-13 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Immunological origins of binding and catalysis in a Diels-Alderase antibody.
Science, 279, 1998
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1D6V
 | | CONFORMATION EFFECTS IN BIOLOGICAL CATALYSIS INTRODUCED BY OXY-COPE ANTIBODY MATURATION | | 分子名称: | (1S,2S,5S)2-(4-GLUTARIDYLBENZYL)-5-PHENYL-1-CYCLOHEXANOL, CADMIUM ION, CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (HEAVY CHAIN), ... | | 著者 | Mundorff, E.C, Hanson, M.A, Schultz, P.G, Stevens, R.C. | | 登録日 | 1999-10-15 | | 公開日 | 2000-02-09 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Conformational effects in biological catalysis: an antibody-catalyzed oxy-cope rearrangement.
Biochemistry, 39, 2000
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1UM5
 | | Catalytic Antibody 21H3 with alcohol substrate | | 分子名称: | 1-PHENYLETHANOL, Antibody 21H3 H chain, Antibody 21H3 L chain | | 著者 | Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C. | | 登録日 | 2003-09-23 | | 公開日 | 2004-10-05 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms
To be Published
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1UM6
 | | catalytic antibody 21h3 | | 分子名称: | antibody 21h3, H chain, L chain | | 著者 | Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C. | | 登録日 | 2003-09-23 | | 公開日 | 2004-10-05 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms
To be Published
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1JES
 | | Crystal Structure of a Copper-Mediated Base Pair in DNA | | 分子名称: | 5'-D(*CP*GP*CP*GP*(DPY)P*AP*TP*(DRP)P*CP*GP*CP*G)-3', COPPER (II) ION | | 著者 | Atwell, S, Meggers, E, Spraggon, G, Schultz, P.G. | | 登録日 | 2001-06-18 | | 公開日 | 2001-11-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of a Copper-Mediated Base Pair in DNA
J.Am.Chem.Soc., 123, 2001
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1GAF
 | | 48G7 HYBRIDOMA LINE FAB COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID | | 分子名称: | 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID, CHIMERIC 48G7 FAB | | 著者 | Wedemayer, G.J, Patten, P.A, Stevens, R.C, Schultz, P.G. | | 登録日 | 1996-02-06 | | 公開日 | 1996-07-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | The immunological evolution of catalysis.
Science, 271, 1996
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1UM4
 | | Catalytic Antibody 21H3 with hapten | | 分子名称: | (1R)-1-PHENYLETHYL 4-(ACETYLAMINO)BENZYLPHOSPHONATE, Antibody 21H3 H chain, Antibody 21H3 L chain | | 著者 | Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C. | | 登録日 | 2003-09-23 | | 公開日 | 2004-10-05 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms
To be Published
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4ZJ1
 | | Crystal Structure of p-acrylamido-phenylalanine modified TEM1 beta-lactamase from Escherichia coli : V216AcrF mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-lactamase TEM, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Xiao, H, Nasertorabi, F, Choi, S, Han, G.W, Reed, S.A, Stevens, R.C, Schultz, P.G. | | 登録日 | 2015-04-28 | | 公開日 | 2015-05-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Exploring the potential impact of an expanded genetic code on protein function.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4ZJ2
 | | Crystal Structure of p-acrylamido-phenylalanine modified TEM1 beta-lactamase from Escherichia coli :E166N mutant | | 分子名称: | Beta-lactamase TEM | | 著者 | Xiao, H, Nasertorabi, F, Choi, S, Han, G.W, Reed, S.A, Stevens, C.S, Schultz, P.G. | | 登録日 | 2015-04-28 | | 公開日 | 2015-05-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Exploring the potential impact of an expanded genetic code on protein function.
Proc.Natl.Acad.Sci.USA, 112, 2015
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1ZH0
 | | Crystal Structure of L-3-(2-napthyl)alanine-tRNA synthetase in complex with L-3-(2-napthyl)alanine | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-(2-NAPHTHYL)-ALANINE, Tyrosyl-tRNA synthetase | | 著者 | Turner, J.M, Graziano, J, Spraggon, G, Schultz, P.G. | | 登録日 | 2005-04-22 | | 公開日 | 2006-04-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural plasticity of an aminoacyl-tRNA synthetase active site
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2AG6
 | | Crystal structure of p-bromo-l-phenylalanine-tRNA sythetase in complex with p-bromo-l-phenylalanine | | 分子名称: | 4-BROMO-L-PHENYLALANINE, Tyrosyl-tRNA synthetase | | 著者 | Turner, J.M, Graziano, J, Spraggon, G, Schultz, P.G. | | 登録日 | 2005-07-26 | | 公開日 | 2006-04-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural plasticity of an aminoacyl-tRNA synthetase active site
Proc.Natl.Acad.Sci.Usa, 103, 2006
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1AJ7
 | | IMMUNOGLOBULIN 48G7 GERMLINE FAB ANTIBODY COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID. AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY | | 分子名称: | 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID, IMMUNOGLOBULIN 48G7 FAB (HEAVY CHAIN), IMMUNOGLOBULIN 48G7 FAB (LIGHT CHAIN) | | 著者 | Wedemayer, G.J, Wang, L.H, Patten, P.A, Schultz, P.G, Stevens, R.C. | | 登録日 | 1997-05-15 | | 公開日 | 1997-11-12 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural insights into the evolution of an antibody combining site.
Science, 276, 1997
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3HWL
 | | Crystal Structure of T4 lysozyme with the unnatural amino acid p-Acetyl-L-Phenylalanine incorporated at position 131 | | 分子名称: | AZIDE ION, CHLORIDE ION, Lysozyme | | 著者 | Fleissner, M.R, Cascio, D, Schultz, P.G, Hubbell, W.L. | | 登録日 | 2009-06-17 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Site-directed spin labeling of a genetically encoded unnatural amino acid.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2HGZ
 | | Crystal structure of a p-benzoyl-L-phenylalanyl-tRNA synthetase | | 分子名称: | PARA-(BENZOYL)-PHENYLALANINE, Tyrosyl-tRNA synthetase | | 著者 | Liu, W, Alfonta, L, Mack, A.V, Schultz, P.G. | | 登録日 | 2006-06-27 | | 公開日 | 2007-06-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for the recognition of para-benzoyl-L-phenylalanine by evolved aminoacyl-tRNA synthetases.
Angew.Chem.Int.Ed.Engl., 46, 2007
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1ZH6
 | | Crystal Structure of p-acetylphenylalanine-tRNA synthetase in complex with p-acetylphenylalanine | | 分子名称: | 4-ACETYL-L-PHENYLALANINE, BETA-MERCAPTOETHANOL, Tyrosyl-tRNA synthetase | | 著者 | Turner, J.M, Graziano, J, Spraggon, G, Schultz, P.G. | | 登録日 | 2005-04-22 | | 公開日 | 2006-04-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural characterization of a p-acetylphenylalanyl aminoacyl-tRNA synthetase.
J.Am.Chem.Soc., 127, 2005
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3RIX
 | | 1.7A resolution structure of a firefly luciferase-Aspulvinone J inhibitor complex | | 分子名称: | (5Z)-4-hydroxy-3-[(2R)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl]-5-{[(2R)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl]methylidene}furan-2(5H)-one, Luciferin 4-monooxygenase | | 著者 | Lovell, S, Battaile, K.P, Lopez, P.C, Auld, D.S, Schultz, P.J, MacArthur, R, Shen, M, Tamayo, G, Inglese, J, Sherman, D.H. | | 登録日 | 2011-04-14 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Titration-based screening for evaluation of natural product extracts: identification of an aspulvinone family of luciferase inhibitors.
Chem.Biol., 18, 2011
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2PIS
 | | Efforts toward Expansion of the Genetic Alphabet: Structure and Replication of Unnatural Base Pairs | | 分子名称: | DNA (5'-D(*CP*GP*(CBR)P*GP*AP*AP*(FFD)P*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION | | 著者 | Matsuda, S, Fillo, J.D, Henry, A.A, Wilkins, S.J, Rai, P, Dwyer, T.J, Geierstanger, B.H, Wemmer, D.E, Schultz, P.G, Spraggon, G, Romesberg, F.E. | | 登録日 | 2007-04-13 | | 公開日 | 2007-10-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs.
J.Am.Chem.Soc., 129, 2007
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1PVQ
 | | BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7 | | 分子名称: | DNA 34-MER, Recombinase cre | | 著者 | Baldwin, E.P, Martin, S.S, Abel, J, Gelato, K.A, Kim, H, Schultz, P.G, Santoro, S.W. | | 登録日 | 2003-06-28 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10, 2003
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1PVR
 | | BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE LOXP (WILDTYPE) RECOGNITION SITE | | 分子名称: | 34-MER, Recombinase CRE | | 著者 | Baldwin, E.P, Martin, S.S, Abel, J, Gelato, K.A, Kim, H, Schultz, P.G, Santoro, S.W. | | 登録日 | 2003-06-28 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10, 2003
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1PVP
 | | BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, ALSHG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7 | | 分子名称: | 34-MER, Recombinase cre | | 著者 | Baldwin, E.P, Martin, S.S, Abel, J, Gelato, K.A, Kim, H, Schultz, P.G, Santoro, S.W. | | 登録日 | 2003-06-28 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10, 2003
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