7MQO
| The insulin receptor ectodomain in complex with a venom hybrid insulin analog - "head" region | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, ... | 著者 | Blakely, A.D, Xiong, X, Kim, J.H, Menting, J, Schafer, I.B, Schubert, H.L, Agrawal, R, Gutmann, T, Delaine, C, Zhang, Y, Artik, G.O, Merriman, A, Eckert, D, Lawrence, M.C, Coskun, U, Fisher, S.J, Forbes, B.E, Safavi-Hemami, H, Hill, C.P, Chou, D.H.C. | 登録日 | 2021-05-06 | 公開日 | 2022-03-16 | 最終更新日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Symmetric and asymmetric receptor conformation continuum induced by a new insulin. Nat.Chem.Biol., 18, 2022
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7MQR
| The insulin receptor ectodomain in complex with four venom hybrid insulins - symmetric conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ... | 著者 | Blakely, A.D, Xiong, X, Kim, J.H, Menting, J, Schafer, I.B, Schubert, H.L, Agrawal, R, Gutmann, T, Delaine, C, Zhang, Y, Artik, G.O, Merriman, A, Eckert, D, Lawrence, M.C, Coskun, U, Fisher, S.J, Forbes, B.E, Safavi-Hemami, H, Hill, C.P, Chou, D.H.C. | 登録日 | 2021-05-06 | 公開日 | 2022-03-16 | 最終更新日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Symmetric and asymmetric receptor conformation continuum induced by a new insulin. Nat.Chem.Biol., 18, 2022
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6PEK
| Structure of Spastin Hexamer (Subunit A-E) in complex with substrate peptide | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | 著者 | Han, H, Schubert, H.L, McCullough, J, Monroe, N, Sundquist, W.I, Hill, C.P. | 登録日 | 2019-06-20 | 公開日 | 2019-12-04 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation. J.Biol.Chem., 295, 2020
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6PEN
| Structure of Spastin Hexamer (whole model) in complex with substrate peptide | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, EYEYEYEYEY, ... | 著者 | Han, H, Schubert, H.L, McCullough, J, Monroe, N, Sundquist, W.I, Hill, C.P. | 登録日 | 2019-06-20 | 公開日 | 2019-12-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation. J.Biol.Chem., 295, 2020
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3LL9
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3OYZ
| Haloferax volcanii Malate Synthase Pyruvate/Acetyl-CoA Ternary Complex | 分子名称: | ACETYL COENZYME *A, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Howard, B.R, Bracken, C, Neighbor, A, Thomas, G, Lamlenn, K.K, Schubert, H.L, Whitby, F.G. | 登録日 | 2010-09-24 | 公開日 | 2011-06-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G. Bmc Struct.Biol., 11, 2011
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3OYX
| Haloferax volcanii Malate Synthase Magnesium/Glyoxylate Complex | 分子名称: | CHLORIDE ION, GLYOXYLIC ACID, MAGNESIUM ION, ... | 著者 | Howard, B.R, Bracken, C, Neighbor, A, Thomas, G, Lamlenn, K.K, Schubert, H.L, Whitby, F.G. | 登録日 | 2010-09-24 | 公開日 | 2011-06-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G. Bmc Struct.Biol., 11, 2011
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1JPK
| Gly156Asp mutant of Human UroD, human uroporphyrinogen III decarboxylase | 分子名称: | UROPORPHYRINOGEN DECARBOXYLASE | 著者 | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | 登録日 | 2001-08-02 | 公開日 | 2001-12-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase. Blood, 98, 2001
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1JR2
| Structure of Uroporphyrinogen III Synthase | 分子名称: | UROPORPHYRINOGEN-III SYNTHASE | 著者 | Mathews, M.A, Schubert, H.L, Whitby, F.G, Alexander, K.J, Schadick, K, Bergonia, H.A, Phillips, J.D, Hill, C.P. | 登録日 | 2001-08-10 | 公開日 | 2001-11-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Crystal structure of human uroporphyrinogen III synthase. EMBO J., 20, 2001
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1JPH
| Ile260Thr mutant of Human UroD, human uroporphyrinogen III decarboxylase | 分子名称: | UROPORPHYRINOGEN DECARBOXYLASE | 著者 | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | 登録日 | 2001-08-02 | 公開日 | 2001-12-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase. Blood, 98, 2001
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1JPI
| Phe232Leu mutant of human UROD, human uroporphyrinogen III decarboxylase | 分子名称: | UROPORPHYRINOGEN DECARBOXYLASE | 著者 | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | 登録日 | 2001-08-02 | 公開日 | 2001-12-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase. Blood, 98, 2001
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1S4D
| Crystal Structure Analysis of the S-adenosyl-L-methionine dependent uroporphyrinogen-III C-methyltransferase SUMT | 分子名称: | GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, Uroporphyrin-III C-methyltransferase | 著者 | Vevodova, J, Graham, R.M, Raux, E, Schubert, H.L, Roper, D.I, Brindley, A.A, Scott, A.I, Roessner, C.A, Stamford, N.P.J, Stroupe, M.E, Getzoff, E.D, Warren, M.J, Wilson, K.S. | 登録日 | 2004-01-16 | 公開日 | 2004-11-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure/Function Studies on a S-Adenosyl-l-methionine-dependent Uroporphyrinogen III C Methyltransferase (SUMT), a Key Regulatory Enzyme of Tetrapyrrole Biosynthesis J.Mol.Biol., 344, 2004
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1S1Q
| TSG101(UEV) domain in complex with Ubiquitin | 分子名称: | ACETIC ACID, COPPER (II) ION, SULFATE ION, ... | 著者 | Sundquist, W.I, Schubert, H.L, Kelly, B.N, Hill, G.C, Holton, J.M, Hill, C.P. | 登録日 | 2004-01-07 | 公開日 | 2004-05-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Ubiquitin recognition by the human TSG101 protein Mol.Cell, 13, 2004
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1Z3Y
| Structure of Gun4-1 from Thermosynechococcus elongatus | 分子名称: | putative cytidylyltransferase | 著者 | Davison, P.A, Schubert, H.L, Reid, J.D, Iorg, C.D, Robinson, H, Hill, C.P, Hunter, C.N. | 登録日 | 2005-03-14 | 公開日 | 2005-06-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and Biochemical Characterization of Gun4 Suggests a Mechanism for Its Role in Chlorophyll Biosynthesis(,). Biochemistry, 44, 2005
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1Z3X
| Structure of Gun4 from Thermosynechococcus elongatus | 分子名称: | putative cytidylyltransferase | 著者 | Davison, P.A, Schubert, H.L, Reid, J.D, Iorg, C.D, Robinson, H, Hill, C.P, Hunter, C.N. | 登録日 | 2005-03-14 | 公開日 | 2005-06-07 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural and Biochemical Characterization of Gun4 Suggests a Mechanism for Its Role in Chlorophyll Biosynthesis(,). Biochemistry, 44, 2005
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1XXV
| Yersinia YopH (residues 163-468) binds phosphonodifluoromethyl-Phe containing hexapeptide at two sites | 分子名称: | Epidermal growth factor receptor derived peptide, Protein-tyrosine phosphatase yopH | 著者 | Ivanov, M.I, Stuckey, J.A, Schubert, H.L, Saper, M.A, Bliska, J.B. | 登録日 | 2004-11-08 | 公開日 | 2005-03-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Two substrate-targeting sites in the Yersinia protein tyrosine phosphatase co-operate to promote bacterial virulence Mol.Microbiol., 55, 2005
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1ZY7
| Crystal structure of the catalytic domain of an adenosine deaminase that acts on RNA (hADAR2) bound to inositol hexakisphosphate (IHP) | 分子名称: | INOSITOL HEXAKISPHOSPHATE, RNA-specific adenosine deaminase B1, isoform DRADA2a, ... | 著者 | Macbeth, M.R, Schubert, H.L, Vandemark, A.P, Lingam, A.T, Hill, C.P, Bass, B.L. | 登録日 | 2005-06-09 | 公開日 | 2005-09-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing. Science, 309, 2005
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1XXP
| Yersinia YopH (residues 163-468) C403S binds phosphotyrosyl peptide at two sites | 分子名称: | Hexapeptide ASP-ALA-ASP-GLU-PTR-CLE, Protein-tyrosine phosphatase yopH | 著者 | Ivanov, M.I, Stuckey, J.A, Schubert, H.L, Saper, M.A, Bliska, J.B. | 登録日 | 2004-11-07 | 公開日 | 2005-03-22 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Two substrate-targeting sites in the Yersinia protein tyrosine phosphatase co-operate to promote bacterial virulence Mol.Microbiol., 55, 2005
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3FRV
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