1ZY7
Crystal structure of the catalytic domain of an adenosine deaminase that acts on RNA (hADAR2) bound to inositol hexakisphosphate (IHP)
Summary for 1ZY7
| Entry DOI | 10.2210/pdb1zy7/pdb |
| Descriptor | RNA-specific adenosine deaminase B1, isoform DRADA2a, ZINC ION, INOSITOL HEXAKISPHOSPHATE, ... (5 entities in total) |
| Functional Keywords | alpha/beta deaminase motif, zinc coordination, ionsitol hexakisphosphate, hydrolase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 91557.72 |
| Authors | Macbeth, M.R.,Schubert, H.L.,Vandemark, A.P.,Lingam, A.T.,Hill, C.P.,Bass, B.L. (deposition date: 2005-06-09, release date: 2005-09-13, Last modification date: 2024-02-14) |
| Primary citation | Macbeth, M.R.,Schubert, H.L.,Vandemark, A.P.,Lingam, A.T.,Hill, C.P.,Bass, B.L. Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing. Science, 309:1534-1539, 2005 Cited by PubMed: 16141067DOI: 10.1126/science.1113150 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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