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PDB: 22 results

4U0G
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BU of 4u0g by Molmil
Crystal Structure of M. tuberculosis ClpP1P2 bound to ADEP and agonist
Descriptor: ADEP-2B5Me, ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2, ...
Authors:Schmitz, K.R, Carney, D.W, Sello, J.K, Sauer, R.T.
Deposit date:2014-07-11
Release date:2014-10-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.1978 Å)
Cite:Crystal structure of Mycobacterium tuberculosis ClpP1P2 suggests a model for peptidase activation by AAA+ partner binding and substrate delivery.
Proc.Natl.Acad.Sci.USA, 111, 2014
4U0H
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BU of 4u0h by Molmil
Crystal Structure of M. tuberculosis ClpP1P1
Descriptor: ATP-dependent Clp protease proteolytic subunit 1, SULFATE ION
Authors:Schmitz, K.R, Carney, D.W, Sello, J.K, Sauer, R.T.
Deposit date:2014-07-11
Release date:2014-10-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.2479 Å)
Cite:Crystal structure of Mycobacterium tuberculosis ClpP1P2 suggests a model for peptidase activation by AAA+ partner binding and substrate delivery.
Proc.Natl.Acad.Sci.USA, 111, 2014
3KN1
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BU of 3kn1 by Molmil
Crystal Structure of Golgi Phosphoprotein 3 N-term Truncation Variant
Descriptor: Golgi phosphoprotein 3, SULFATE ION
Authors:Schmitz, K.R, Bessman, N.J, Setty, T.G, Ferguson, K.M.
Deposit date:2009-11-11
Release date:2009-12-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking.
J.Cell Biol., 187, 2009
2ZIH
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BU of 2zih by Molmil
Crystal Structure of Yeast Vps74
Descriptor: Vacuolar protein sorting-associated protein 74
Authors:Schmitz, K.R, Li, S, Setty, T.G, Ferguson, K.M.
Deposit date:2008-02-18
Release date:2008-04-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Golgi localization of glycosyltransferases requires a Vps74p oligomer.
Dev.Cell, 14, 2008
2ZII
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BU of 2zii by Molmil
Crystal Structure of Yeast Vps74-N-term Truncation Variant
Descriptor: Vacuolar protein sorting-associated protein 74
Authors:Schmitz, K.R, Li, S, Setty, T.G, Ferguson, K.M.
Deposit date:2008-02-18
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Golgi localization of glycosyltransferases requires a Vps74p oligomer.
Dev.Cell, 14, 2008
3EGA
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BU of 3ega by Molmil
Crystal structure of Pellino2 FHA Domain at 1.8 Angstroms resolution
Descriptor: Protein pellino homolog 2, SULFATE ION
Authors:Ferguson, K.M, Lin, C, Schmitz, K.R.
Deposit date:2008-09-10
Release date:2008-12-23
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1.
Structure, 16, 2008
3EGB
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BU of 3egb by Molmil
Structure of Pellino2 FHA domain at 3.3 Angstroms resolution.
Descriptor: Protein pellino homolog 2
Authors:Ferguson, K.M, Lin, C, Schmitz, K.R.
Deposit date:2008-09-10
Release date:2008-12-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1.
Structure, 16, 2008
4KRP
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BU of 4krp by Molmil
Nanobody/VHH domain 9G8 in complex with the extracellular region of EGFR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab heavy chain, ...
Authors:Ferguson, K.M, Schmitz, K.R.
Deposit date:2013-05-16
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.823 Å)
Cite:Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains.
Structure, 21, 2013
4KRO
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Nanobody/VHH domain EgA1 in complex with the extracellular region of EGFR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab heavy chain, ...
Authors:Ferguson, K.M, Schmitz, K.R.
Deposit date:2013-05-16
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.054 Å)
Cite:Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains.
Structure, 21, 2013
4KRM
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BU of 4krm by Molmil
Nanobody/VHH domain 7D12 in complex with domain III of the extracellular region of EGFR, pH 3.5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:Ferguson, K.M, Schmitz, K.R.
Deposit date:2013-05-16
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.655 Å)
Cite:Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains.
Structure, 21, 2013
4KRN
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BU of 4krn by Molmil
Nanobody/VHH domain EgA1
Descriptor: Nanobody/VHH domain EgA1, SULFATE ION
Authors:Ferguson, K.M, Schmitz, K.R.
Deposit date:2013-05-16
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.553 Å)
Cite:Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains.
Structure, 21, 2013
4KRL
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BU of 4krl by Molmil
Nanobody/VHH domain 7D12 in complex with domain III of the extracellular region of EGFR, pH 6.0
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ferguson, K.M, Schmitz, K.R.
Deposit date:2013-05-16
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.849 Å)
Cite:Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains.
Structure, 21, 2013
4I5O
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BU of 4i5o by Molmil
Crystal Structure of W-W-R ClpX Hexamer
Descriptor: ATP-dependent Clp protease ATP-binding subunit ClpX, SULFATE ION
Authors:Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T.
Deposit date:2012-11-28
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.4787 Å)
Cite:Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine.
Cell(Cambridge,Mass.), 153, 2013
4I9K
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BU of 4i9k by Molmil
Crystal structure of symmetric W-W-W ClpX Hexamer
Descriptor: ATP-dependent Clp protease ATP-binding subunit ClpX, SULFATE ION
Authors:Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T.
Deposit date:2012-12-05
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (5.0003 Å)
Cite:Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine.
Cell(Cambridge,Mass.), 153, 2013
4I63
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BU of 4i63 by Molmil
Crystal Structure of E-R ClpX Hexamer
Descriptor: ATP-dependent Clp protease ATP-binding subunit ClpX, SULFATE ION
Authors:Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T.
Deposit date:2012-11-29
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (5.709 Å)
Cite:Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine.
Cell(Cambridge,Mass.), 153, 2013
1YY9
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BU of 1yy9 by Molmil
Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab Heavy chain, ...
Authors:Li, S, Schmitz, K.R, Jeffrey, P.D, Wiltzius, J.J.W, Kussie, P, Ferguson, K.M.
Deposit date:2005-02-24
Release date:2005-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.605 Å)
Cite:Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
Cancer Cell, 7, 2005
4I34
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BU of 4i34 by Molmil
Crystal Structure of W-W-W ClpX Hexamer
Descriptor: ATP-dependent Clp protease ATP-binding subunit ClpX, SULFATE ION
Authors:Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T.
Deposit date:2012-11-23
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.1218 Å)
Cite:Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine.
Cell(Cambridge,Mass.), 153, 2013
4I4L
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BU of 4i4l by Molmil
Crystal Structure of Nucleotide-Bound W-W-W ClpX Hexamer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, SULFATE ION
Authors:Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T.
Deposit date:2012-11-27
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.6981 Å)
Cite:Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine.
Cell(Cambridge,Mass.), 153, 2013
4I81
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BU of 4i81 by Molmil
Crystal Structure of ATPgS bound ClpX Hexamer
Descriptor: ATP-dependent Clp protease ATP-binding subunit ClpX, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, SULFATE ION
Authors:Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T.
Deposit date:2012-12-01
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.8182 Å)
Cite:Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine.
Cell(Cambridge,Mass.), 153, 2013
1YY8
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BU of 1yy8 by Molmil
Crystal structure of the Fab fragment from the monoclonal antibody cetuximab/Erbitux/IMC-C225
Descriptor: Cetuximab Fab Heavy chain, Cetuximab Fab Light chain
Authors:Li, S, Schmitz, K.R, Jeffrey, P.D, Wiltzius, J.J.W, Kussie, P, Ferguson, K.M.
Deposit date:2005-02-24
Release date:2005-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
Cancer Cell, 7, 2005
5JI3
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BU of 5ji3 by Molmil
HslUV complex
Descriptor: 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV
Authors:Grant, R.A, Sauer, R.T, Schmitz, K.R, Baytshtok, V.
Deposit date:2016-04-21
Release date:2016-12-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis.
Structure, 24, 2016
5JI2
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HslU L199Q in HslUV complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV, ...
Authors:Grant, R.A, Sauer, R.T, Schmitz, K.R, Baytshtok, V.
Deposit date:2016-04-21
Release date:2016-11-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.307 Å)
Cite:A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis.
Structure, 24, 2016

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