7NBW
 
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8BTJ
 | | Murine cytomegalovirus protein M35 | | 分子名称: | (R,R)-2,3-BUTANEDIOL, MALONATE ION, Protein M35 | | 著者 | Schmelz, S, Van den Heuvel, J, Blankenfeldt, W. | | 登録日 | 2022-11-29 | | 公開日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | The Cytomegalovirus M35 Protein Directly Binds to the Interferon-beta Enhancer and Modulates Transcription of Ifnb1 and Other IRF3-Driven Genes.
J.Virol., 97, 2023
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5FZP
 | | Structure of the dispase autolysis inducing protein from Streptomyces mobaraensis | | 分子名称: | CALCIUM ION, DISPASE AUTOLYSIS-INDUCING PROTEIN, GLYCEROL | | 著者 | Schmelz, S, Fiebig, D, Beck, J, Fuchsbauer, H.L, Scrima, A. | | 登録日 | 2016-03-15 | | 公開日 | 2016-08-10 | | 最終更新日 | 2016-10-05 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of the Dispase Autolysis Inducing Protein from Streptomyces Mobaraensis and Glutamine Cross-Linking Sites for Transglutaminase
J.Biol.Chem., 291, 2016
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6I0I
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6YIZ
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6GMG
 | | Structure of a glutamine donor mimicking inhibitory peptide shaped by the catalytic cleft of microbial transglutaminase | | 分子名称: | CITRATE ANION, DI(HYDROXYETHYL)ETHER, PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE, ... | | 著者 | Schmelz, S, Juettner, N.E, Fuchsbauer, H.L, Scrima, A. | | 登録日 | 2018-05-25 | | 公開日 | 2018-10-24 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure of a glutamine donor mimicking inhibitory peptide shaped by the catalytic cleft of microbial transglutaminase.
FEBS J., 285, 2018
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6YA1
 | | Zinc metalloprotease ProA | | 分子名称: | ACETATE ION, CALCIUM ION, ZINC ION, ... | | 著者 | Schmelz, S, Blankenfeldt, W. | | 登録日 | 2020-03-11 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Zinc metalloprotease ProA of Legionella pneumophila increases alveolar septal thickness in human lung tissue explants by collagen IV degradation.
Cell.Microbiol., 23, 2021
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6YZE
 | | Zinc metalloprotease ProA from native source | | 分子名称: | ZINC ION, Zinc metalloproteinase | | 著者 | Schmelz, S, Blankenfeldt, W. | | 登録日 | 2020-05-06 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Zinc metalloprotease ProA of Legionella pneumophila increases alveolar septal thickness in human lung tissue explants by collagen IV degradation.
Cell.Microbiol., 23, 2021
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6FHP
 | | DAIP in complex with a C-terminal fragment of thermolysin | | 分子名称: | Dispase autolysis-inducing protein, Thermolysin | | 著者 | Schmelz, S, Fiebig, D, Fuchsbauer, H.L, Blankenfeldt, W, Scrima, A. | | 登録日 | 2018-01-15 | | 公開日 | 2018-09-12 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.703 Å) | | 主引用文献 | Destructive twisting of neutral metalloproteases: the catalysis mechanism of the Dispase autolysis-inducing protein from Streptomyces mobaraensis DSM 40487.
FEBS J., 285, 2018
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7P4U
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7QA0
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7QA3
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7QAV
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4CH7
 | | Crystal structure of the siroheme decarboxylase NirDL | | 分子名称: | NIRD-LIKE PROTEIN | | 著者 | Schmelz, S, Kriegler, T.M, Haufschildt, K, Layer, G, Heinz, D.W. | | 登録日 | 2013-11-29 | | 公開日 | 2014-07-30 | | 最終更新日 | 2014-09-10 | | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | | 主引用文献 | The Crystal Structure of Siroheme Decarboxylase in Complex with Iron-Uroporphyrin III Reveals Two Essential Histidine Residues
J.Mol.Biol., 426, 2014
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4CZC
 | | Crystal structure of the siroheme decarboxylase NirDL in co-complex with iron-uroporphyrin III analogue | | 分子名称: | Fe(III) Uroporphyrin, NIRD-LIKE PROTEIN | | 著者 | Schmelz, S, Kriegler, T.M, Haufschildt, K, Layer, G, Heinz, D.W. | | 登録日 | 2014-04-17 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The Crystal Structure of Siroheme Decarboxylase in Complex with Iron-Uroporphyrin III Reveals Two Essential Histidine Residues
J.Mol.Biol., 426, 2014
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5OJY
 | | Co-complex structure of regulator protein 2 (PamR2) with pamamycin 607 from Streptomyces alboniger | | 分子名称: | CITRIC ACID, GLYCEROL, Pamamycin 607, ... | | 著者 | Schmelz, S, Rebets, Y, Luzhetskyy, A, Scrima, A. | | 登録日 | 2017-07-24 | | 公開日 | 2018-04-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | | 主引用文献 | Design, development and application of whole-cell based antibiotic-specific biosensor.
Metab. Eng., 47, 2018
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5OJX
 | | Crystal structure of regulator protein 2 (PamR2) from the pamamycin biosynthetic gene cluster of Streptomyces alboniger | | 分子名称: | TetR family transcription regulator | | 著者 | Schmelz, S, Rebets, Y, Luzhetskyy, A, Scrima, A. | | 登録日 | 2017-07-24 | | 公開日 | 2018-04-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Design, development and application of whole-cell based antibiotic-specific biosensor.
Metab. Eng., 47, 2018
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5NTB
 | | Streptomyces papain inhibitor (SPI) | | 分子名称: | Papain inhibitor, SULFATE ION | | 著者 | Schmelz, S, Juettner, N.E, Fuchsbauer, H.L, Scrima, A. | | 登録日 | 2017-04-27 | | 公開日 | 2018-03-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Illuminating structure and acyl donor sites of a physiological transglutaminase substrate from Streptomyces mobaraensis.
Protein Sci., 27, 2018
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4ALZ
 | | The Yersinia T3SS basal body component YscD reveals a different structural periplasmatic domain organization to known homologue PrgH | | 分子名称: | GLYCEROL, PHOSPHATE ION, YOP PROTEINS TRANSLOCATION PROTEIN D | | 著者 | Schmelz, S, Wisand, U, Stenta, M, Muenich, S, Widow, U, Cornelis, G.R, Heinz, D.W. | | 登録日 | 2012-03-06 | | 公開日 | 2013-04-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | In Situ Structural Analysis of the Yersinia Enterocolitica Injectisome.
Elife, 2, 2013
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4A1T
 | | Co-Complex of the of NS3-4A protease with the inhibitory peptide CP5- 46-A (in-House data) | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BICARBONATE ION, CHLORIDE ION, ... | | 著者 | Schmelz, S, Kuegler, J, Collins, J, Heinz, D.W. | | 登録日 | 2011-09-19 | | 公開日 | 2012-09-19 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | High Affinity Peptide Inhibitors of the Hepatitis C Virus Ns3-4A Protease Refractory to Common Resistant Mutants.
J.Biol.Chem., 287, 2012
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4A1X
 | | Co-Complex structure of NS3-4A protease with the inhibitory peptide CP5-46-A (Synchrotron data) | | 分子名称: | CHLORIDE ION, CP5-46-A PEPTIDE, NONSTRUCTURAL PROTEIN 4A, ... | | 著者 | Schmelz, S, Kuegler, J, Collins, J, Heinz, D. | | 登録日 | 2011-09-20 | | 公開日 | 2012-09-19 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | High Affinity Peptide Inhibitors of the Hepatitis C Virus Ns3-4A Protease Refractory to Common Resistant Mutants.
J.Biol.Chem., 287, 2012
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4A1V
 | | Co-Complex structure of NS3-4A protease with the optimized inhibitory peptide CP5-46A-4D5E | | 分子名称: | CHLORIDE ION, CP5-46A-4D5E, NON-STRUCTURAL PROTEIN 4A, ... | | 著者 | Schmelz, S, Kuegler, J, Collins, J, Heinz, D.W. | | 登録日 | 2011-09-20 | | 公開日 | 2012-09-19 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | High Affinity Peptide Inhibitors of the Hepatitis C Virus Ns3-4A Protease Refractory to Common Resistant Mutants.
J.Biol.Chem., 287, 2012
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4AOR
 | | Cationic trypsin in complex with the Spinacia oleracea trypsin inhibitor III (SOTI-III) | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CATIONIC TRYPSIN, ... | | 著者 | Schmelz, S, Glotzbach, B, Reinwarth, M, Christmann, A, Kolmar, H, Heinz, D.W. | | 登録日 | 2012-03-29 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | | 主引用文献 | Structural Characterization of Spinacia Oleracea Trypsin Inhibitor III (Soti-III)
Acta Crystallogr.,Sect.D, 69, 2013
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4ABI
 | | Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (PtA)SFTI-1(1,14), that was 1,4-disubstituted with a 1,2,3- trizol to mimic a trans amide bond | | 分子名称: | CALCIUM ION, CATIONIC TRYPSIN, DIMETHYLFORMAMIDE, ... | | 著者 | Schmelz, S, Empting, M, Tischler, M, Nasu, D, Heinz, D, Kolmar, H. | | 登録日 | 2011-12-08 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Braces for the Peptide Backbone: Insights Into Structure-Activity Relation-Ships of Protease Inhibitor Mimics with Locked Amide Conformations
Angew.Chem.Int.Ed.Engl., 51, 2012
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4ABJ
 | | Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (IcA)SFTI-1(1,14), that was 1,5-disubstituted with 1,2,3- trizol to mimic a cis amide bond | | 分子名称: | CALCIUM ION, CATIONIC TRYPSIN, DIMETHYLFORMAMIDE, ... | | 著者 | Schmelz, S, Empting, M, Tischler, M, Nasu, D, Heinz, D, Kolmar, H. | | 登録日 | 2011-12-08 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Braces for the Peptide Backbone: Insights Into Structure-Activity Relation-Ships of Protease Inhibitor Mimics with Locked Amide Conformations
Angew.Chem.Int.Ed.Engl., 51, 2012
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