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PDB: 68 件
6SUA
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BU of 6sua by Molmil
Structure of the high affinity engineered lipocalin C1B12 in complex with the mouse CD98 heavy chain ectodomain
分子名称: 4F2 cell-surface antigen heavy chain, Neutrophil gelatinase-associated lipocalin, SULFATE ION
著者Schiefner, A, Deuschle, F.-C, Skerra, A.
登録日2019-09-13
公開日2020-06-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Design of a surrogate Anticalin protein directed against CD98hc for preclinical studies in mice.
Protein Sci., 29, 2020
6S8V
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BU of 6s8v by Molmil
Structure of the high affinity Anticalin P3D11 in complex with the human CD98 heavy chain ectodomain
分子名称: 1,2-ETHANEDIOL, 4F2 cell-surface antigen heavy chain, Neutrophil gelatinase-associated lipocalin
著者Schiefner, A, Deuschle, F.-C, Skerra, A.
登録日2019-07-10
公開日2020-03-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Development of a high affinity Anticalin®directed against human CD98hc for theranostic applications.
Theranostics, 10, 2020
6YJX
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BU of 6yjx by Molmil
Structure of Hen egg-white lysozyme crystallized with PAS polypeptide
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
著者Schiefner, A, Skerra, A.
登録日2020-04-05
公開日2020-07-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Proline/alanine-rich sequence (PAS) polypeptides as an alternative to PEG precipitants for protein crystallization.
Acta Crystallogr.,Sect.F, 76, 2020
6YJW
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BU of 6yjw by Molmil
Structure of Fragaria ananassa O-methyltransferase crystallized with PAS polypeptide
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, O-methyltransferase, ...
著者Schiefner, A, Skerra, A.
登録日2020-04-05
公開日2020-07-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Proline/alanine-rich sequence (PAS) polypeptides as an alternative to PEG precipitants for protein crystallization.
Acta Crystallogr.,Sect.F, 76, 2020
5E9O
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BU of 5e9o by Molmil
Spirochaeta thermophila X module - CBM64 - mutant G504A
分子名称: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, Cellulase, glycosyl hydrolase family 5, ...
著者Schiefner, A, Skerra, A.
登録日2015-10-15
公開日2016-03-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for cellulose binding by the type A carbohydrate-binding module 64 of Spirochaeta thermophila.
Proteins, 84, 2016
5E9P
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BU of 5e9p by Molmil
Spirochaeta thermophila X module - CBM64 - wildtype
分子名称: Cellulase, glycosyl hydrolase family 5, TPS linker, ...
著者Schiefner, A, Skerra, A.
登録日2015-10-15
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural basis for cellulose binding by the type A carbohydrate-binding module 64 of Spirochaeta thermophila.
Proteins, 84, 2016
1Z6R
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BU of 1z6r by Molmil
Crystal structure of Mlc from Escherichia coli
分子名称: Mlc protein, ZINC ION
著者Schiefner, A, Gerber, K, Seitz, S, Welte, W, Diederichs, K, Boos, W.
登録日2005-03-23
公開日2005-06-14
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of Mlc, a global regulator of sugar metabolism in Escherichia coli
J.Biol.Chem., 280, 2005
4GH7
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BU of 4gh7 by Molmil
Crystal structure of Anticalin N7A in complex with oncofetal fibronectin fragment Fn7B8
分子名称: Fibronectin, Neutrophil gelatinase-associated lipocalin
著者Schiefner, A, Gebauer, M, Skerra, A.
登録日2012-08-07
公開日2012-12-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Combinatorial design of an Anticalin directed against the extra-domain b for the specific targeting of oncofetal fibronectin
J.Mol.Biol., 425, 2013
6I9Q
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BU of 6i9q by Molmil
Structure of the mouse CD98 heavy chain ectodomain
分子名称: 1,2-ETHANEDIOL, 4F2 cell-surface antigen heavy chain, CHLORIDE ION
著者Schiefner, A, Deuschle, F.-C, Skerra, A.
登録日2018-11-24
公開日2019-04-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural differences between the ectodomains of murine and human CD98hc.
Proteins, 87, 2019
3T1W
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BU of 3t1w by Molmil
Structure of the four-domain fragment Fn7B89 of oncofetal fibronectin
分子名称: four-domain fibronectin fragment
著者Schiefner, A, Skerra, A.
登録日2011-07-22
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Extra-domain B in oncofetal fibronectin structurally promotes fibrillar head-to-tail dimerization of extracellular matrix protein.
J.Biol.Chem., 287, 2012
4RUN
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BU of 4run by Molmil
Crystal structure of human odorant binding protein OBPIIa
分子名称: CITRATE ANION, Odorant-binding protein 2a
著者Schiefner, A, Skerra, A.
登録日2014-11-21
公開日2015-04-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the human odorant binding protein, OBPIIa.
Proteins, 83, 2015
3LRH
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BU of 3lrh by Molmil
Structure of anti-huntingtin VL domain in complex with huntingtin peptide
分子名称: Huntingtin, anti-huntingtin VL domain
著者Schiefner, A, Chatwell, L, Skerra, A.
登録日2010-02-11
公開日2011-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Disulfide-Free Single-Domain V(L) Intrabody with Blocking Activity towards Huntingtin Reveals a Novel Mode of Epitope Recognition.
J.Mol.Biol., 414, 2011
3LRG
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BU of 3lrg by Molmil
Structure of anti-huntingtin VL domain
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IMIDAZOLE, anti-huntingtin VL domain
著者Schiefner, A, Chatwell, L, Skerra, A.
登録日2010-02-11
公開日2011-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A Disulfide-Free Single-Domain V(L) Intrabody with Blocking Activity towards Huntingtin Reveals a Novel Mode of Epitope Recognition.
J.Mol.Biol., 414, 2011
3MBT
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BU of 3mbt by Molmil
Structure of monomeric Blc from E. coli
分子名称: Outer membrane lipoprotein blc
著者Schiefner, A, Skerra, A.
登録日2010-03-26
公開日2010-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and biochemical analyses reveal a monomeric state of the bacterial lipocalin Blc.
Acta Crystallogr.,Sect.D, 66, 2010
4R0B
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BU of 4r0b by Molmil
Structure of dimeric human glycodelin
分子名称: Glycodelin
著者Schiefner, A, Skerra, A.
登録日2014-07-30
公開日2014-12-10
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The dimeric crystal structure of the human fertility lipocalin glycodelin reveals a protein scaffold for the presentation of complex glycans.
Biochem.J., 466, 2015
5N47
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BU of 5n47 by Molmil
Structure of Anticalin N7E in complex with the three-domain fragment Fn7B8 of human oncofetal fibronectin
分子名称: Fibronectin, Neutrophil gelatinase-associated lipocalin
著者Schiefner, A, Skerra, A.
登録日2017-02-10
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Anticalins Reveal High Plasticity in the Mode of Complex Formation with a Common Tumor Antigen.
Structure, 26, 2018
5N48
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BU of 5n48 by Molmil
Structure of Anticalin N9B in complex with extra-domain B of human oncofetal fibronectin
分子名称: Fibronectin, Neutrophil gelatinase-associated lipocalin
著者Schiefner, A, Skerra, A.
登録日2017-02-10
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Anticalins Reveal High Plasticity in the Mode of Complex Formation with a Common Tumor Antigen.
Structure, 26, 2018
5N5V
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BU of 5n5v by Molmil
Structure of p-boronophenylalanyl tRNA synthetase - apo form
分子名称: CHLORIDE ION, Tyrosine--tRNA ligase
著者Schiefner, A, Skerra, A.
登録日2017-02-14
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for the Specific Cotranslational Incorporation of p-Boronophenylalanine into Biosynthetic Proteins.
Biochemistry, 57, 2018
5N5U
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BU of 5n5u by Molmil
Structure of p-boronophenylalanyl tRNA synthetase in complex with p-boronophenylalanine and adenosine monophosphate
分子名称: 4-Borono-L-phenylalanine, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
著者Schiefner, A, Skerra, A.
登録日2017-02-14
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Basis for the Specific Cotranslational Incorporation of p-Boronophenylalanine into Biosynthetic Proteins.
Biochemistry, 57, 2018
4IDF
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BU of 4idf by Molmil
Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and HMF
分子名称: 1,2-ETHANEDIOL, 4-hydroxy-5-methylfuran-3(2H)-one, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Schiefner, A, Skerra, A.
登録日2012-12-12
公開日2013-04-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone
J.Biol.Chem., 288, 2013
4IDC
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Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and HDMF
分子名称: (2R)-4-hydroxy-2,5-dimethylfuran-3(2H)-one, 1,2-ETHANEDIOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Schiefner, A, Skerra, A.
登録日2012-12-12
公開日2013-04-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone
J.Biol.Chem., 288, 2013
4IDB
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BU of 4idb by Molmil
Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADP+
分子名称: 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Ripening-induced protein, ...
著者Schiefner, A, Skerra, A.
登録日2012-12-12
公開日2013-04-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone
J.Biol.Chem., 288, 2013
4IDD
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BU of 4idd by Molmil
Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and EHMF
分子名称: (2R)-2-ethyl-4-hydroxy-5-methylfuran-3(2H)-one, 1,2-ETHANEDIOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Schiefner, A, Skerra, A.
登録日2012-12-12
公開日2013-04-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone
J.Biol.Chem., 288, 2013
4IDE
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Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADP+ and EDHMF
分子名称: (2E)-2-ethylidene-4-hydroxy-5-methylfuran-3(2H)-one, 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Schiefner, A, Skerra, A.
登録日2012-12-12
公開日2013-04-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone
J.Biol.Chem., 288, 2013
4IDA
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BU of 4ida by Molmil
Structure of the Fragaria x ananassa enone oxidoreductase in its apo form
分子名称: 1,2-ETHANEDIOL, Ripening-induced protein, SULFATE ION
著者Schiefner, A, Skerra, A.
登録日2012-12-12
公開日2013-04-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone
J.Biol.Chem., 288, 2013

 

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