Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 133 results

1K4Q
DownloadVisualize
BU of 1k4q by Molmil
Human Glutathione Reductase Inactivated by Peroxynitrite
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Glutathione Reductase
Authors:Savvides, S.N, Scheiwein, M, Boehme, C.C, Arteel, G.E, Karplus, P.A, Becker, K, Schirmer, R.H.
Deposit date:2001-10-08
Release date:2002-01-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the antioxidant enzyme glutathione reductase inactivated by peroxynitrite.
J.Biol.Chem., 277, 2002
1OPX
DownloadVisualize
BU of 1opx by Molmil
Crystal structure of the traffic ATPase (HP0525) of the Helicobacter pylori type IV secretion system bound by sulfate
Descriptor: NONAETHYLENE GLYCOL, SULFATE ION, virB11 homolog
Authors:Savvides, S.N, Yeo, H.J, Beck, M.R, Blaesing, F, Lurz, R, Lanka, E, Buhrdorf, R, Fischer, W, Haas, R, Waksman, G.
Deposit date:2003-03-06
Release date:2003-05-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:VirB11 ATPases are dynamic hexameric assemblies: New insights into bacterial type IV secretion
Embo J., 22, 2003
1NLZ
DownloadVisualize
BU of 1nlz by Molmil
Crystal structure of unliganded traffic ATPase of the type IV secretion system of helicobacter pylori
Descriptor: virB11 homolog
Authors:Savvides, S.N, Yeo, H.J, Beck, M.R, Blaesing, F, Lurz, R, Lanka, E, Buhrdorf, R, Fischer, W, Haas, R, Waksman, G.
Deposit date:2003-01-08
Release date:2003-05-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:VirB11 ATPases are dynamic hexameric assemblies: New insights into bacterial type IV secretion
Embo J., 22, 2003
1NLY
DownloadVisualize
BU of 1nly by Molmil
Crystal structure of the traffic ATPase of the Helicobacter pylori type IV secretion system in complex with ATPgammaS
Descriptor: MAGNESIUM ION, NONAETHYLENE GLYCOL, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Savvides, S.N, Yeo, H.J, Beck, M.R, Blaesing, F, Lurz, R, Lanka, E, Buhrdorf, R, Fischer, W, Haas, R, Waksman, G.
Deposit date:2003-01-08
Release date:2003-05-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:VirB11 ATPases are dynamic hexameric assemblies: New insights into bacterial type IV secretion
Embo J., 22, 2003
1SRU
DownloadVisualize
BU of 1sru by Molmil
Crystal structure of full length E. coli SSB protein
Descriptor: Single-strand binding protein
Authors:Savvides, S.N, Raghunathan, S, Fuetterer, K, Kozlov, A.G, Lohman, T.M, Waksman, G.
Deposit date:2004-03-23
Release date:2004-08-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The C-terminal domain of full-length E. coli SSB is disordered even when bound to DNA.
Protein Sci., 13, 2004
1XAN
DownloadVisualize
BU of 1xan by Molmil
HUMAN GLUTATHIONE REDUCTASE IN COMPLEX WITH A XANTHENE INHIBITOR
Descriptor: 3,6-DIHYDROXY-XANTHENE-9-PROPIONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE
Authors:Savvides, S.N, Karplus, P.A.
Deposit date:1996-01-26
Release date:1996-07-11
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kinetics and crystallographic analysis of human glutathione reductase in complex with a xanthene inhibitor.
J.Biol.Chem., 271, 1996
1ETE
DownloadVisualize
BU of 1ete by Molmil
CRYSTAL STRUCTURE OF THE FLT3 LIGAND
Descriptor: FLT3 LIGAND, ZINC ION
Authors:Savvides, S.N, Boone, T, Karplus, P.A.
Deposit date:2000-04-12
Release date:2000-06-14
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Flt3 ligand structure and unexpected commonalities of helical bundles and cystine knots.
Nat.Struct.Biol., 7, 2000
2GOU
DownloadVisualize
BU of 2gou by Molmil
Structure of wild type, oxidized SYE1, an OYE homologue from S. oneidensis
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, FLAVIN MONONUCLEOTIDE, ...
Authors:Savvides, S.N, van den Hemel, D.
Deposit date:2006-04-14
Release date:2006-07-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Ligand-induced conformational changes in the capping subdomain of a bacterial old yellow enzyme homologue and conserved sequence fingerprints provide new insights into substrate binding.
J.Biol.Chem., 281, 2006
2GQA
DownloadVisualize
BU of 2gqa by Molmil
Structure of NADH-reduced SYE1, an OYE homologue from S. oneidensis
Descriptor: FLAVIN MONONUCLEOTIDE, SULFATE ION, oxidoreductase, ...
Authors:Savvides, S.N, van den Hemel, D.
Deposit date:2006-04-20
Release date:2006-07-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Ligand-induced conformational changes in the capping subdomain of a bacterial old yellow enzyme homologue and conserved sequence fingerprints provide new insights into substrate binding.
J.Biol.Chem., 281, 2006
2GQ9
DownloadVisualize
BU of 2gq9 by Molmil
Structure of SYE1, an OYE homologue from S. oneidensis, in complex with p-hydroxybenzaldehyde
Descriptor: FLAVIN MONONUCLEOTIDE, P-HYDROXYBENZALDEHYDE, SULFATE ION, ...
Authors:Savvides, S.N, van den Hemel, D.
Deposit date:2006-04-20
Release date:2006-07-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Ligand-induced conformational changes in the capping subdomain of a bacterial old yellow enzyme homologue and conserved sequence fingerprints provide new insights into substrate binding.
J.Biol.Chem., 281, 2006
2I9V
DownloadVisualize
BU of 2i9v by Molmil
Structural role of Y98 in PYP: effects on fluorescence, gateway and photocycle recovery
Descriptor: 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein
Authors:Savvides, S.N, Kyndt, J.
Deposit date:2006-09-06
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural role of tyrosine 98 in photoactive yellow protein: effects on fluorescence, gateway, and photocycle recovery.
Biochemistry, 46, 2007
2GQ8
DownloadVisualize
BU of 2gq8 by Molmil
Structure of SYE1, an OYE homologue from S. ondeidensis, in complex with p-hydroxyacetophenone
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLAVIN MONONUCLEOTIDE, P-HYDROXYACETOPHENONE, ...
Authors:Savvides, S.N, van den Hemel, D.
Deposit date:2006-04-20
Release date:2006-07-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Ligand-induced conformational changes in the capping subdomain of a bacterial old yellow enzyme homologue and conserved sequence fingerprints provide new insights into substrate binding.
J.Biol.Chem., 281, 2006
7OX6
DownloadVisualize
BU of 7ox6 by Molmil
Solution structure of human interleukin-9
Descriptor: Interleukin-9
Authors:Savvides, S.N, Tripsianes, K, De Vos, T, Papageorgiou, A, Evangelidis, T.
Deposit date:2021-06-22
Release date:2022-12-28
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9)
Biorxiv, 2022
8QMG
DownloadVisualize
BU of 8qmg by Molmil
Tobacco lectin Nictaba in apo state including I and Eu SAD datasets.
Descriptor: Nictaba, ZINC ION
Authors:Bloch, Y, Savvides, S.N.
Deposit date:2023-09-22
Release date:2023-11-08
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of Nictaba reveals its carbohydrate-binding properties and a new lectin dimerization mode.
Glycobiology, 2024
7R3N
DownloadVisualize
BU of 7r3n by Molmil
mouse Interleukin-12 subunit beta - p80 homodimer in space group P21 crystal form 3
Descriptor: Interleukin-12 subunit beta, PHOSPHATE ION, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Bloch, Y, Savvides, S.N.
Deposit date:2022-02-07
Release date:2022-05-04
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Around she goes: the structure of mouse Interleukin-12 p80
To Be Published
8AVB
DownloadVisualize
BU of 8avb by Molmil
Cryo-EM structure for mouse leptin in complex with the mouse LEP-R ectodomain (1:2 mLEP:mLEPR model).
Descriptor: Leptin, Leptin receptor
Authors:Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
Deposit date:2022-08-26
Release date:2023-04-05
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.43 Å)
Cite:Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
7AL7
DownloadVisualize
BU of 7al7 by Molmil
The Crystal Structure of Human IL-18 in Complex With Human IL-18 Binding Protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutathione S-transferase class-mu 26 kDa isozyme,Interleukin-18, Interleukin-18-binding protein
Authors:Detry, S, Andries, J, Bloch, Y, Clancy, D, Savvides, S.N.
Deposit date:2020-10-05
Release date:2022-04-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity.
J.Biol.Chem., 298, 2022
4WRL
DownloadVisualize
BU of 4wrl by Molmil
Structure of the human CSF-1:CSF-1R complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage colony-stimulating factor 1, Macrophage colony-stimulating factor 1 receptor, ...
Authors:Felix, J, De Munck, S, Elegheert, J, Savvides, S.N.
Deposit date:2014-10-24
Release date:2015-08-12
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Structure and Assembly Mechanism of the Signaling Complex Mediated by Human CSF-1.
Structure, 23, 2015
4WRM
DownloadVisualize
BU of 4wrm by Molmil
Structure of the human CSF-1:CSF-1R complex
Descriptor: Macrophage colony-stimulating factor 1, Macrophage colony-stimulating factor 1 receptor
Authors:Felix, J, De Munck, S, Elegheert, J, Savvides, S.N.
Deposit date:2014-10-24
Release date:2015-08-12
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (6.853 Å)
Cite:Structure and Assembly Mechanism of the Signaling Complex Mediated by Human CSF-1.
Structure, 23, 2015
5D28
DownloadVisualize
BU of 5d28 by Molmil
Complex of GM-CSF/IL-2 inhibition factor with Granulocyte-macrophage colony-stimulating factor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GM-CSF/IL-2 inhibition factor, ...
Authors:Felix, J, Savvides, S.N.
Deposit date:2015-08-05
Release date:2016-11-16
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.845 Å)
Cite:Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF.
Nat Commun, 7, 2016
5D22
DownloadVisualize
BU of 5d22 by Molmil
Structure of ovine granulocyte-macrophage colony-stimulating factor
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Granulocyte-macrophage colony-stimulating factor
Authors:Felix, J, Savvides, S.N.
Deposit date:2015-08-05
Release date:2016-11-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.994 Å)
Cite:Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF.
Nat Commun, 7, 2016
2NNC
DownloadVisualize
BU of 2nnc by Molmil
Structure of the sulfur carrier protein SoxY from Chlorobium limicola f thiosulfatophilum
Descriptor: CHLORIDE ION, NITROGEN MOLECULE, PHOSPHATE ION, ...
Authors:Stout, J, Van Driessche, G, Savvides, S.N, Van Beeumen, J.
Deposit date:2006-10-24
Release date:2007-03-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:X-ray crystallographic analysis of the sulfur carrier protein SoxY from Chlorobium limicola f. thiosulfatophilum reveals a tetrameric structure.
Protein Sci., 16, 2007
2NNF
DownloadVisualize
BU of 2nnf by Molmil
Structure of the sulfur carrier protein SoxY from Chlorobium limicola f thiosulfatophilum
Descriptor: PHOSPHATE ION, Sulfur covalently-binding protein
Authors:Stout, J, Van Driessche, G, Savvides, S.N, Van Beeumen, J.
Deposit date:2006-10-24
Release date:2007-03-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:X-ray crystallographic analysis of the sulfur carrier protein SoxY from Chlorobium limicola f. thiosulfatophilum reveals a tetrameric structure.
Protein Sci., 16, 2007
4NN6
DownloadVisualize
BU of 4nn6 by Molmil
Cytokine receptor complex - Crystal form 1B
Descriptor: Cytokine receptor-like factor 2, Interleukin-7 receptor subunit alpha, Thymic stromal lymphopoietin
Authors:Verstraete, K, van Schie, L, Savvides, S.N.
Deposit date:2013-11-16
Release date:2014-03-19
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.545 Å)
Cite:Structural basis of the proinflammatory signaling complex mediated by TSLP.
Nat.Struct.Mol.Biol., 21, 2014
4NN5
DownloadVisualize
BU of 4nn5 by Molmil
Cytokine receptor complex - Crystal form 1A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Cytokine receptor-like factor 2, ...
Authors:Verstraete, K, van Schie, L, Savvides, S.N.
Deposit date:2013-11-16
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.898 Å)
Cite:Structural basis of the proinflammatory signaling complex mediated by TSLP.
Nat.Struct.Mol.Biol., 21, 2014

227561

PDB entries from 2024-11-20

PDB statisticsPDBj update infoContact PDBjnumon