2MF9
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![BU of 2mf9 by Molmil](/molmil-images/mine/2mf9) | Solution structure of the N-terminal domain of human FKBP38 (FKBP38NTD) | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP8 | Authors: | Kang, C, Ye, H, Simon, B, Sattler, M, Yoon, H.S. | Deposit date: | 2013-10-08 | Release date: | 2013-11-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Functional role of the flexible N-terminal extension of FKBP38 in catalysis. Sci Rep, 3, 2013
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1OQJ
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![BU of 1oqj by Molmil](/molmil-images/mine/1oqj) | Crystal structure of the SAND domain from glucocorticoid modulatory element binding protein-1 (GMEB1) | Descriptor: | Glucocorticoid Modulatory Element Binding protein-1, ZINC ION | Authors: | Surdo, P.L, Bottomley, M.J, Sattler, M, Scheffzek, K. | Deposit date: | 2003-03-10 | Release date: | 2003-11-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure and nuclear magnetic resonance analyses of the SAND domain from glucocorticoid modulatory element binding protein-1 reveals deoxyribonucleic acid and zinc binding regions MOL.ENDOCRINOL., 17, 2003
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1LXL
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![BU of 1lxl by Molmil](/molmil-images/mine/1lxl) | NMR STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH, MINIMIZED AVERAGE STRUCTURE | Descriptor: | BCL-XL | Authors: | Muchmore, S.W, Sattler, M, Liang, H, Meadows, R.P, Harlan, J.E, Yoon, H.S, Nettesheim, D, Chang, B.S, Thompson, C.B, Wong, S.L, Ng, S.C, Fesik, S.W. | Deposit date: | 1996-04-04 | Release date: | 1997-04-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature, 381, 1996
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1OPI
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![BU of 1opi by Molmil](/molmil-images/mine/1opi) | SOLUTION STRUCTURE OF THE THIRD RNA RECOGNITION MOTIF (RRM) OF U2AF65 IN COMPLEX WITH AN N-TERMINAL SF1 PEPTIDE | Descriptor: | SPLICING FACTOR SF1, SPLICING FACTOR U2AF 65 KDA SUBUNIT | Authors: | Selenko, P, Gregorovic, G, Sprangers, R, Stier, G, Rhani, Z, Kramer, A, Sattler, M. | Deposit date: | 2003-03-05 | Release date: | 2004-03-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP Mol.Cell, 11, 2003
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6RZS
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![BU of 6rzs by Molmil](/molmil-images/mine/6rzs) | Structure of IMP-13 metallo-beta-lactamase complexed with hydrolysed ertapenem | Descriptor: | Beta-lactamase, ZINC ION, hydrolysed ertapenem | Authors: | Zak, K.M, Softley, C, Kolonko, M, Sattler, M, Popowicz, G.M. | Deposit date: | 2019-06-13 | Release date: | 2020-04-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase. Antimicrob.Agents Chemother., 64, 2020
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6RT2
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![BU of 6rt2 by Molmil](/molmil-images/mine/6rt2) | Crystal structure of Trypanosoma Brucei PEX14 N-terminal domain in complex with small molecules designed to investigate the water envelope | Descriptor: | (3~{S})-3-[[1-(2-hydroxyethyl)-5-[(4-methoxynaphthalen-1-yl)methyl]-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridin-3-yl]carbonylamino]-3-phenyl-propanoic acid, BETA-MERCAPTOETHANOL, Peroxin 14, ... | Authors: | Napolitano, V, Ratkova, E.L, Dawidowski, M, Dubin, G, Fino, R, Popowicz, G, Sattler, M, Tetko, I.V. | Deposit date: | 2019-05-22 | Release date: | 2020-04-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Water envelope has a critical impact on the design of protein-protein interaction inhibitors. Chem.Commun.(Camb.), 56, 2020
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6RZR
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![BU of 6rzr by Molmil](/molmil-images/mine/6rzr) | Structure of IMP-13 metallo-beta-lactamase complexed with hydrolysed imipenem | Descriptor: | (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase, ... | Authors: | Zak, K.M, Softley, C, Kolonko, M, Sattler, M, Popowicz, G.M. | Deposit date: | 2019-06-13 | Release date: | 2020-04-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase. Antimicrob.Agents Chemother., 64, 2020
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4QI2
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![BU of 4qi2 by Molmil](/molmil-images/mine/4qi2) | X-ray structure of the ROQ domain from murine Roquin-1 in complex with a 23-mer Tnf-CDE RNA | Descriptor: | RNA (5'-R(*AP*CP*AP*UP*GP*UP*UP*UP*UP*CP*UP*GP*UP*GP*AP*AP*AP*AP*CP*GP*GP*AP*G)-3'), Roquin-1 | Authors: | Janowski, R, Schlundt, A, Sattler, M, Niessing, D. | Deposit date: | 2014-05-30 | Release date: | 2014-07-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation. Nat.Struct.Mol.Biol., 21, 2014
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6STG
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![BU of 6stg by Molmil](/molmil-images/mine/6stg) | Human Rab8a phosphorylated at Ser111 in complex with GPPNP | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Vieweg, S, Mulholland, K, Braeuning, B, Kachariya, N, Lai, Y, Toth, R, Sattler, M, Groll, M, Itzen, A, Muqit, M.M.K. | Deposit date: | 2019-09-10 | Release date: | 2020-04-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72. Biochem.J., 477, 2020
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6STF
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![BU of 6stf by Molmil](/molmil-images/mine/6stf) | Human Rab8a phosphorylated at Ser111 in complex with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-8A | Authors: | Vieweg, S, Mulholland, K, Braeuning, B, Kachariya, N, Lai, Y, Toth, R, Sattler, M, Groll, M, Itzen, A, Muqit, M.M.K. | Deposit date: | 2019-09-10 | Release date: | 2020-04-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72. Biochem.J., 477, 2020
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6S0H
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![BU of 6s0h by Molmil](/molmil-images/mine/6s0h) | Structure of IMP-13 metallo-beta-lactamase complexed with hydrolysed doripenem | Descriptor: | (2~{R},3~{R})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-3-methyl-4-[(3~{S},5~{S})-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-2,3-dihydro-1~{H}-pyrrole-5-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase, ... | Authors: | Zak, K.M, Softley, C, Kolonko, M, Sattler, M, Popowicz, G.M. | Deposit date: | 2019-06-14 | Release date: | 2020-04-01 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase. Antimicrob.Agents Chemother., 64, 2020
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2PE8
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6R79
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![BU of 6r79 by Molmil](/molmil-images/mine/6r79) | Structure of IMP-13 metallo-beta-lactamase in apo form (loop open) | Descriptor: | BETA-MERCAPTOETHANOL, Beta-lactamase, GLYCEROL, ... | Authors: | Zak, K.M, Softley, C, Kolonko, M, Sattler, M, Popowicz, G.M. | Deposit date: | 2019-03-28 | Release date: | 2020-04-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase. Antimicrob.Agents Chemother., 64, 2020
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4QI0
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![BU of 4qi0 by Molmil](/molmil-images/mine/4qi0) | X-ray structure of the ROQ domain from murine Roquin-1 | Descriptor: | 1,2-ETHANEDIOL, Roquin-1 | Authors: | Janowski, R, Schlundt, A, Sattler, M, Niessing, D. | Deposit date: | 2014-05-30 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation. Nat.Struct.Mol.Biol., 21, 2014
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6R73
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![BU of 6r73 by Molmil](/molmil-images/mine/6r73) | Structure of IMP-13 metallo-beta-lactamase complexed with hydrolysed meropenem | Descriptor: | (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoy l)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid, Beta-lactamase, ZINC ION | Authors: | Softley, C.A, Zak, K, Kolonko, M, Sattler, M, Popowicz, G. | Deposit date: | 2019-03-28 | Release date: | 2020-03-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase. Antimicrob.Agents Chemother., 64, 2020
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6R78
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![BU of 6r78 by Molmil](/molmil-images/mine/6r78) | Structure of IMP-13 metallo-beta-lactamase in apo form (loop closed) | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Beta-lactamase, ... | Authors: | Zak, K.M, Softley, C, Kolonko, M, Sattler, M, Popowicz, G.M. | Deposit date: | 2019-03-28 | Release date: | 2020-04-01 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase. Antimicrob.Agents Chemother., 64, 2020
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2PEH
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![BU of 2peh by Molmil](/molmil-images/mine/2peh) | Crystal structure of the UHM domain of human SPF45 in complex with SF3b155-ULM5 | Descriptor: | Splicing factor 3B subunit 1, Splicing factor 45 | Authors: | Corsini, L, Basquin, J, Hothorn, M, Sattler, M. | Deposit date: | 2007-04-03 | Release date: | 2007-06-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | U2AF-homology motif interactions are required for alternative splicing regulation by SPF45. Nat.Struct.Mol.Biol., 14, 2007
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6ELD
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![BU of 6eld by Molmil](/molmil-images/mine/6eld) | |
6F8G
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![BU of 6f8g by Molmil](/molmil-images/mine/6f8g) | |
4A24
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![BU of 4a24 by Molmil](/molmil-images/mine/4a24) | Structural and functional analysis of the DEAF-1 and BS69 MYND domains | Descriptor: | DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG, ZINC ION | Authors: | Kateb, F, Perrin, H, Tripsianes, K, Zou, P, Spadaccini, R, Bottomley, M, Bepperling, A, Ansieau, S, Sattler, M. | Deposit date: | 2011-09-22 | Release date: | 2012-11-07 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structural and Functional Analysis of the Deaf-1 and Bs69 Mynd Domains. Plos One, 8, 2013
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4A4G
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![BU of 4a4g by Molmil](/molmil-images/mine/4a4g) | Solution structure of SMN Tudor domain in complex with asymmetrically dimethylated arginine | Descriptor: | NG,NG-DIMETHYL-L-ARGININE, SURVIVAL MOTOR NEURON PROTEIN | Authors: | Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M. | Deposit date: | 2011-10-12 | Release date: | 2011-11-30 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins Nat.Struct.Mol.Biol., 18, 2011
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6F8F
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4A4F
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![BU of 4a4f by Molmil](/molmil-images/mine/4a4f) | Solution structure of SPF30 Tudor domain in complex with symmetrically dimethylated arginine | Descriptor: | N3, N4-DIMETHYLARGININE, SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30 | Authors: | Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M. | Deposit date: | 2011-10-12 | Release date: | 2011-11-30 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins Nat.Struct.Mol.Biol., 18, 2011
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4A4E
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![BU of 4a4e by Molmil](/molmil-images/mine/4a4e) | Solution structure of SMN Tudor domain in complex with symmetrically dimethylated arginine | Descriptor: | N3, N4-DIMETHYLARGININE, SURVIVAL MOTOR NEURON PROTEIN | Authors: | Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M. | Deposit date: | 2011-10-12 | Release date: | 2011-11-30 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins Nat.Struct.Mol.Biol., 18, 2011
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4A4H
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![BU of 4a4h by Molmil](/molmil-images/mine/4a4h) | Solution structure of SPF30 Tudor domain in complex with asymmetrically dimethylated arginine | Descriptor: | NG,NG-DIMETHYL-L-ARGININE, SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30 | Authors: | Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M. | Deposit date: | 2011-10-12 | Release date: | 2011-11-30 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins Nat.Struct.Mol.Biol., 18, 2011
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