6R73
Structure of IMP-13 metallo-beta-lactamase complexed with hydrolysed meropenem
Summary for 6R73
Entry DOI | 10.2210/pdb6r73/pdb |
Descriptor | Beta-lactamase, (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoy l)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid, ZINC ION, ... (4 entities in total) |
Functional Keywords | metallo-beta-lactamase, zinc-binding protein, antibiotic resistance, hydrolase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 51285.66 |
Authors | Softley, C.A.,Zak, K.,Kolonko, M.,Sattler, M.,Popowicz, G. (deposition date: 2019-03-28, release date: 2020-03-25, Last modification date: 2024-01-24) |
Primary citation | Softley, C.A.,Zak, K.M.,Bostock, M.J.,Fino, R.,Zhou, R.X.,Kolonko, M.,Mejdi-Nitiu, R.,Meyer, H.,Sattler, M.,Popowicz, G.M. Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase. Antimicrob.Agents Chemother., 64:-, 2020 Cited by PubMed: 32205343DOI: 10.1128/AAC.00123-20 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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