8DMH
 
 | | Lymphocytic choriomeningitis virus glycoprotein in complex with neutralizing antibody M28 | | 分子名称: | 18.5C-M28 Fab Heavy Chain, 18.5C-M28 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Moon-Walker, A, Hastie, K.M, Zyla, D.S, Saphire, E.O. | | 登録日 | 2022-07-08 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Structural basis for antibody-mediated neutralization of lymphocytic choriomeningitis virus.
Cell Chem Biol, 30, 2023
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8DMI
 | | Lymphocytic choriomeningitis virus glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G1, ... | | 著者 | Moon-Walker, A, Hastie, K.M, Zyla, D.S, Saphire, E.O. | | 登録日 | 2022-07-08 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Structural basis for antibody-mediated neutralization of lymphocytic choriomeningitis virus.
Cell Chem Biol, 30, 2023
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7U9G
 | | Rabies virus glycoprotein pre-fusion trimer in complex with neutralizing antibody RVA122 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein, RVA122 Fab Heavy Chain, ... | | 著者 | Callaway, H.M, Zyla, D, Larrous, F, Dias de Melo, G, Hastie, K.M, Avalos, R.D, Agarwal, A, Bouhry, H, Corti, D, Saphire, E.O. | | 登録日 | 2022-03-10 | | 公開日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Structure of the rabies virus glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Sci Adv, 8, 2022
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8DPM
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8DPL
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7UOV
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7UOT
 | | Native Lassa glycoprotein in complex with neutralizing antibodies 8.9F and 37.2D | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 37.2D heavy chain (variable domain), ... | | 著者 | Li, H, Saphire, E.O. | | 登録日 | 2022-04-13 | | 公開日 | 2022-11-02 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | A cocktail of protective antibodies subverts the dense glycan shield of Lassa virus.
Sci Transl Med, 14, 2022
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8F0G
 | | Structure of SARS-CoV-2 Omicron BA.1 spike in complex with antibody Fab 1C3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 1C3 Fab Heavy Chain, ... | | 著者 | Yu, X, Zyla, D, Hastie, K.M, Saphire, E.O. | | 登録日 | 2022-11-02 | | 公開日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence.
Cell Rep, 42, 2023
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8F0H
 | | Structure of SARS-CoV-2 spike with antibody Fabs 2A10 and 1H2 (Local refinement of the RBD and Fabs 1H2 and 2A10) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 1H2 heavy chain, Antibody Fab 1H2 light chain, ... | | 著者 | Yu, X, Zyla, D, Hastie, K.M, Saphire, E.O. | | 登録日 | 2022-11-02 | | 公開日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence.
Cell Rep, 42, 2023
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8E1G
 | | SARS-CoV-2 RBD in complex with Omicron-neutralizing antibody 2A10 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2A10 Fab, heavy chain, ... | | 著者 | Wasserman, H, Hastie, K.M, Buck, T.K, Saphire, E.O. | | 登録日 | 2022-08-10 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence.
Cell Rep, 42, 2023
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7K5L
 | | Ebola virus VP40 octameric ring generated by an RNA oligonucleotide | | 分子名称: | HSP RNA oligonucleotide, Matrix protein VP40 | | 著者 | Landeras-Bueno, S, Wasserman, H, Salie, Z.L, Saphire, E.O. | | 登録日 | 2020-09-17 | | 公開日 | 2021-04-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form.
Cell Rep, 35, 2021
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7K5D
 | | Ebola virus VP40 octameric ring generated by a DNA oligonucleotide | | 分子名称: | HSP DNA oligonucleotide, Matrix protein VP40 | | 著者 | Landeras-Bueno, S, Wasserman, H, Salie, Z.L, Saphire, E.O. | | 登録日 | 2020-09-16 | | 公開日 | 2021-04-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form.
Cell Rep, 35, 2021
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5TOI
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5UQY
 | | Crystal structure of Marburg virus GP in complex with the human survivor antibody MR78 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE GLYCOPROTEIN GP1, ... | | 著者 | Hashiguchi, T, Fusco, M.L, Hastie, K.M, Bomholdt, Z.A, Lee, J.E, Flyak, A.I, Matsuoka, R, Kohda, D, Yanagi, Y, Hammel, M, Crowe, J.E, Saphire, E.O. | | 登録日 | 2017-02-08 | | 公開日 | 2017-03-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural basis for Marburg virus neutralization by a cross-reactive human antibody.
Cell, 160, 2015
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5T3T
 | | Ebola virus VP30 CTD bound to nucleoprotein | | 分子名称: | Fusion protein of Nucleoprotein and Minor nucleoprotein VP30, SULFATE ION | | 著者 | Kirchdoerfer, R.N, Moyer, C.L, Abelson, D.M, Saphire, E.O. | | 登録日 | 2016-08-26 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The Ebola Virus VP30-NP Interaction Is a Regulator of Viral RNA Synthesis.
Plos Pathog., 12, 2016
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5TOH
 | | Crystal Structure of the Marburg Virus VP35 Oligomerization Domain I2 | | 分子名称: | Polymerase cofactor VP35 | | 著者 | Bruhn, J.F, Kirchdoerfer, R.N, Tickle, I.J, Bricogne, G, Saphire, E.O. | | 登録日 | 2016-10-17 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Crystal Structure of the Marburg Virus VP35 Oligomerization Domain.
J. Virol., 91, 2017
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5VK2
 | | Structural basis for antibody-mediated neutralization of Lassa virus | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Hastie, K.M, Zandonatti, M.A, Kleinfelter, L.M, Rowland, M.L, Rowland, M.M, Chandra, K, Branco, L.M, Robinson, J.E, Garry, R.F, Saphire, E.O. | | 登録日 | 2017-04-20 | | 公開日 | 2017-05-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.201 Å) | | 主引用文献 | Structural basis for antibody-mediated neutralization of Lassa virus.
Science, 356, 2017
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5T3W
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8UT2
 | | Pre-fusion Measles virus fusion protein complexed with Fab 77 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zyla, D, Saphire, E.O. | | 登録日 | 2023-10-30 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | | 主引用文献 | A neutralizing antibody prevents postfusion transition of measles virus fusion protein.
Science, 384, 2024
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9AT8
 | | Fab 77-stabilized MeV F ectodomain fragment | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, mAB 77 heavy chain, ... | | 著者 | Zyla, D, Saphire, E.O. | | 登録日 | 2024-02-26 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | A neutralizing antibody prevents postfusion transition of measles virus fusion protein.
Science, 384, 2024
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8UTF
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8UUP
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8UUQ
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7JZT
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7JZJ
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