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PDB: 2585 results

5GG5
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Crystal structure of Mycobacterium smegmatis MutT1
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Hydrolase, ...
Authors:Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M.
Deposit date:2016-06-15
Release date:2017-04-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017
5GG8
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Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGTP, 8-oxo-dGMP and pyrophosphate (II)
Descriptor: 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Hydrolase, ...
Authors:Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M.
Deposit date:2016-06-15
Release date:2017-04-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017
5GG9
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BU of 5gg9 by Molmil
Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-GTP, 8-oxo-GMP and pyrophosphate
Descriptor: 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, Hydrolase, NUDIX family protein, ...
Authors:Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M.
Deposit date:2016-06-15
Release date:2017-04-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017
5GGA
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Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-GDP, 8-oxo-GMP and pyrophosphate
Descriptor: Hydrolase, NUDIX family protein, MAGNESIUM ION, ...
Authors:Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M.
Deposit date:2016-06-15
Release date:2017-04-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017
3O3F
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T. maritima RNase H2 D107N in complex with nucleic acid substrate and magnesium ions
Descriptor: DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), MAGNESIUM ION, ...
Authors:Rychlik, M.P, Chon, H, Cerritelli, S.M, Klimek, P, Crouch, R.J, Nowotny, M.
Deposit date:2010-07-24
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage.
Mol.Cell, 40, 2010
5GGD
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BU of 5ggd by Molmil
Crystal structure of Mycobacterium smegmatis MutT1 in complex with phosphate and magnesium ions (excess magnesium, II)
Descriptor: Hydrolase, NUDIX family protein, MAGNESIUM ION, ...
Authors:Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M.
Deposit date:2016-06-15
Release date:2017-04-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017
3O8Z
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Crystal structure of Spn1 (Iws1) core domain
Descriptor: SULFATE ION, Transcription factor IWS1
Authors:McDonald, S.M, Close, D, Hill, C.P.
Deposit date:2010-08-03
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure and biological importance of the spn1-spt6 interaction, and its regulatory role in nucleosome binding.
Mol.Cell, 40, 2010
3O3H
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BU of 3o3h by Molmil
T. maritima RNase H2 D107N in complex with nucleic acid substrate and manganese ions
Descriptor: DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), MANGANESE (II) ION, ...
Authors:Rychlik, M.P, Chon, H, Cerritelli, S.M, Klimek, P, Crouch, R.J, Nowotny, M.
Deposit date:2010-07-24
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage.
Mol.Cell, 40, 2010
3NWV
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Human cytochrome c G41S
Descriptor: Cytochrome c, HEME C
Authors:Fagerlund, R.D, Wilbanks, S.M.
Deposit date:2010-07-11
Release date:2011-03-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Proapoptotic G41S Mutation to Human Cytochrome c Alters the Heme Electronic Structure and Increases the Electron Self-Exchange Rate.
J.Am.Chem.Soc., 133, 2011
5KEQ
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BU of 5keq by Molmil
High resolution cryo-EM maps of Human papillomavirus 16 reveal L2 location and heparin-induced conformational changes
Descriptor: Major capsid protein L1
Authors:Guan, J, Bywaters, S.M, Brendle, S.A, Ashley, R.E, Makhov, A.M, Conway, J.F, Christensen, N.D, Hafenstein, S.
Deposit date:2016-06-10
Release date:2017-01-25
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Cryoelectron Microscopy Maps of Human Papillomavirus 16 Reveal L2 Densities and Heparin Binding Site.
Structure, 25, 2017
2X1K
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BU of 2x1k by Molmil
H71S mutant of the antibiotic resistance protein NimA from Deinococcus radiodurans
Descriptor: ACETATE ION, NIMA-RELATED PROTEIN
Authors:Leiros, H.S, Brandsdal, B.O, McSweeney, S.M.
Deposit date:2010-01-07
Release date:2010-11-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Biophysical Characterization and Mutational Analysis of the Antibiotic Resistance Protein Nima from Deinococcus Radiodurans.
Biochim.Biophys.Acta, 1804, 2010
8FTU
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Crystal structure of the SNARE Use1 bound to Dsl1 complex subunits Sec39 and Dsl1, Revised Use1 structure
Descriptor: Protein transport protein DSL1, Protein transport protein SEC39, Vesicle transport protein USE1
Authors:Travis, S.M, Jeffrey, P.D, Hughson, F.M.
Deposit date:2023-01-13
Release date:2023-03-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (5.73 Å)
Cite:Structure of a membrane tethering complex incorporating multiple SNAREs.
Nat.Struct.Mol.Biol., 31, 2024
1WQ6
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The tetramer structure of the nervy homolgy two (NHR2) domain of AML1-ETO is critical for AML1-ETO'S activity
Descriptor: AML1-ETO
Authors:Liu, Y, Cheney, M.D, Chruszcz, M, Lukasik, S.M, Hartman, K.L, Laue, T.M, Dauter, Z, Minor, W, Speck, N.A, Bushweller, J.H.
Deposit date:2004-09-23
Release date:2005-10-04
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity
Cancer Cell, 9, 2006
1HFO
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BU of 1hfo by Molmil
The Structure of the Macrophage Migration Inhibitory Factor from Trichinella Spiralis.
Descriptor: MIGRATION INHIBITORY FACTOR
Authors:Roe, S.M, Meyer, D.J.
Deposit date:2000-12-07
Release date:2001-08-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Macrophage Migration Inhibitory Factor of the Parasitic Nematode Trichinella Spiralis
Biochem.J., 357, 2001
1IJD
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BU of 1ijd by Molmil
Crystallographic Structure of the LH3 Complex from Rhodopseudomonas acidophila strain 7050
Descriptor: BACTERIOCHLOROPHYLL A, LIGHT-HARVESTING PROTEIN B-800/820, ALPHA CHAIN, ...
Authors:McLuskey, K, Prince, S.M, Cogdell, R.J, Isaacs, N.W.
Deposit date:2001-04-25
Release date:2001-10-17
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystallographic structure of the B800-820 LH3 light-harvesting complex from the purple bacteria Rhodopseudomonas acidophila strain 7050.
Biochemistry, 40, 2001
8SLO
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BU of 8slo by Molmil
Plasmodium falciparum M1 aminopeptidase bound to selective inhibitor MIPS2673
Descriptor: 2-hydroxy-N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)ethyl]-2-methylpropanamide, GLYCEROL, M1 family aminopeptidase, ...
Authors:McGowan, S.M, Drinkwater, N.
Deposit date:2023-04-24
Release date:2024-04-03
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as an antimalarial strategy.
Elife, 13, 2024
2Y4R
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BU of 2y4r by Molmil
CRYSTAL STRUCTURE OF 4-AMINO-4-DEOXYCHORISMATE LYASE FROM PSEUDOMONAS AERUGINOSA
Descriptor: 1,2-ETHANEDIOL, 4-AMINO-4-DEOXYCHORISMATE LYASE, CHLORIDE ION, ...
Authors:O'Rourke, P.E.F, Eadsforth, T.C, Fyfe, P.K, Shepard, S.M, Agacan, M, Hunter, W.N.
Deposit date:2011-01-10
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Pseudomonas Aeruginosa 4-Amino-4-Deoxychorismate Lyase: Spatial Conservation of an Active Site Tyrosine and Classification of Two Types of Enzyme.
Plos One, 6, 2011
1WYZ
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BU of 1wyz by Molmil
X-Ray structure of the putative methyltransferase from Bacteroides thetaiotaomicron VPI-5482 at the resolution 2.5 A. Norteast Structural Genomics Consortium target Btr28
Descriptor: putative S-adenosylmethionine-dependent methyltransferase
Authors:Kuzin, A.P, Chen, Y, Forouhar, F, Vorobiev, S.M, Acton, T, Ma, L.-C, Xiao, R, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-02-21
Release date:2005-03-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-Ray structure of the putative methyltransferase from Bacteroides thetaiotaomicron VPI-5482 at the resolution 2.5 A. Norteast Structural Genomics Consortium target Btr28
To be Published
1XDV
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BU of 1xdv by Molmil
Experimentally Phased Structure of Human the Son of Sevenless protein at 4.1 Ang.
Descriptor: Son of sevenless protein homolog 1
Authors:Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J.
Deposit date:2004-09-08
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structural analysis of autoinhibition in the ras activator son of sevenless.
Cell(Cambridge,Mass.), 119, 2004
1GNP
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BU of 1gnp by Molmil
X-RAY CRYSTAL STRUCTURE ANALYSIS OF THE CATALYTIC DOMAIN OF THE ONCOGENE PRODUCT P21H-RAS COMPLEXED WITH CAGED GTP AND MANT DGPPNHP
Descriptor: C-H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID 3'-O-(N-METHYLANTHRANILOYL-2'-DEOXYGUANYLATE ESTER
Authors:Scheidig, A, Franken, S.M, Corrie, J.E.T, Reid, G.P, Wittinghofer, A, Pai, E.F, Goody, R.S.
Deposit date:1995-05-11
Release date:1995-07-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray crystal structure analysis of the catalytic domain of the oncogene product p21H-ras complexed with caged GTP and mant dGppNHp.
J.Mol.Biol., 253, 1995
5KUX
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BU of 5kux by Molmil
Designed influenza hemagglutinin binding protein HSB.2
Descriptor: Designed influenza inhibitor protein HSB.2
Authors:Lee, P.S, Bernard, S.M, Wilson, I.A.
Deposit date:2016-07-13
Release date:2017-06-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.
Nat. Biotechnol., 35, 2017
5KUY
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BU of 5kuy by Molmil
Influenza hemagglutinin H3 A/Hong Kong/1/1968 in complex with designed inhibitor protein HSB.2A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Designed influenza inhibitor HSB.2A, ...
Authors:Bernard, S.M, Wilson, I.A.
Deposit date:2016-07-13
Release date:2017-06-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.
Nat. Biotechnol., 35, 2017
1X9Q
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4m5.3 anti-fluorescein single chain antibody fragment (scFv)
Descriptor: 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, 4m5.3 anti-fluorescein single chain antibody fragment, ACETATE ION
Authors:Midelfort, K.S, Hernandez, H.H, Lippow, S.M, Tidor, B, Drennan, C.L, Wittrup, K.D.
Deposit date:2004-08-24
Release date:2005-03-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Substantial energetic improvement with minimal structural perturbation in a high affinity mutant antibody
J.Mol.Biol., 343, 2004
1XBH
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BU of 1xbh by Molmil
A BETA-HAIRPIN MIMIC FROM FCERI-ALPHA-CYCLO(L-262)
Descriptor: PROTEIN (CYCLO(L-262))
Authors:Mcdonnell, J.M, Fushman, D, Cahill, S.M, Sutton, B.J, Cowburn, D.
Deposit date:1999-02-17
Release date:1999-02-21
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Solution Structures of FceRI Alpha-Chain Mimics: A Beta-Hairpin Peptide and Its Retroenantiomer
J.Am.Chem.Soc., 119, 1997
2X1J
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BU of 2x1j by Molmil
H71A mutant of the antibiotic resistance protein NimA from Deinococcus radiodurans
Descriptor: ACETATE ION, NIMA-RELATED PROTEIN
Authors:Leiros, H.S, Brandsdal, B.O, McSweeney, S.M.
Deposit date:2010-01-07
Release date:2010-11-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Biophysical Characterization and Mutational Analysis of the Antibiotic Resistance Protein Nima from Deinococcus Radiodurans.
Biochim.Biophys.Acta, 1804, 2010

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