4UWQ
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![BU of 4uwq by Molmil](/molmil-images/mine/4uwq) | Crystal structure of the disulfide-linked complex of the thiosulfodyrolase SoxB with the carrier-protein SoxYZ from Thermus thermophilus | Descriptor: | MANGANESE (II) ION, SOXY PROTEIN, SOXZ, ... | Authors: | Grabarczyk, D.B, Chappell, P.E, Johnson, S, Stelzl, L.S, Lea, S.M, Berks, B.C. | Deposit date: | 2014-08-14 | Release date: | 2015-12-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.28 Å) | Cite: | Structural Basis for Specificity and Promiscuity in a Carrier Protein/Enzyme System from the Sulfur Cycle Proc.Natl.Acad.Sci.USA, 112, 2015
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4UU3
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![BU of 4uu3 by Molmil](/molmil-images/mine/4uu3) | Ferulic acid decarboxylase from Enterobacter sp. | Descriptor: | FERULIC ACID DECARBOXYLASE | Authors: | Hromic, A, Pavkov-Keller, T, Steinkellner, G, Lyskowski, A, Wuensch, C, Gross, J, Fuchs, M, Fauland, K, Glueck, S.M, Faber, K, Gruber, K. | Deposit date: | 2014-07-24 | Release date: | 2015-06-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Regioselective Enzymatic Beta-Carboxylation of Para-Hydroxy-Styrene Derivatives Catalyzed by Phenolic Acid Decarboxylases. Adv. Synth. Catal., 357, 2015
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6VV6
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![BU of 6vv6 by Molmil](/molmil-images/mine/6vv6) | Mycobacterium tuberculosis dihydrofolate reductase in complex with JEB113 | Descriptor: | 1-(4-fluorophenyl)-5-[3-(1H-indol-3-yl)propoxy]-1H-pyrazole-4-carboxylic acid, COBALT (II) ION, Dihydrofolate reductase, ... | Authors: | Ribeiro, J.A, Dias, M.V.B, Chaves-Pacheco, S.M. | Deposit date: | 2020-02-17 | Release date: | 2020-07-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.235 Å) | Cite: | Using a Fragment-Based Approach to Identify Alternative Chemical Scaffolds Targeting Dihydrofolate Reductase fromMycobacterium tuberculosis. Acs Infect Dis., 6, 2020
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4V47
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![BU of 4v47 by Molmil](/molmil-images/mine/4v47) | Real space refined coordinates of the 30S and 50S subunits fitted into the low resolution cryo-EM map of the EF-G.GTP state of E. coli 70S ribosome | Descriptor: | 16S RIBOSOMAL RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Gao, H, Sengupta, J, Valle, M, Korostelev, A, Eswar, N, Stagg, S.M, Van Roey, P, Agrawal, R.K, Harvey, S.T, Sali, A, Chapman, M.S, Frank, J. | Deposit date: | 2003-05-06 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (12.3 Å) | Cite: | Study of the structural dynamics of the E. coli 70S ribosome using real space refinement Cell(Cambridge,Mass.), 113, 2003
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6W1X
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![BU of 6w1x by Molmil](/molmil-images/mine/6w1x) | Cryo-EM structure of anti-CRISPR AcrIF9, bound to the type I-F crRNA-guided CRISPR surveillance complex | Descriptor: | CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, CRISPR-associated protein Csy3, ... | Authors: | Hirschi, M, Santiago-Frangos, A, Wilkinson, R, Golden, S.M, Wiedenheft, B, Lander, G. | Deposit date: | 2020-03-04 | Release date: | 2020-05-13 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | AcrIF9 tethers non-sequence specific dsDNA to the CRISPR RNA-guided surveillance complex. Nat Commun, 11, 2020
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5KEQ
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![BU of 5keq by Molmil](/molmil-images/mine/5keq) | High resolution cryo-EM maps of Human papillomavirus 16 reveal L2 location and heparin-induced conformational changes | Descriptor: | Major capsid protein L1 | Authors: | Guan, J, Bywaters, S.M, Brendle, S.A, Ashley, R.E, Makhov, A.M, Conway, J.F, Christensen, N.D, Hafenstein, S. | Deposit date: | 2016-06-10 | Release date: | 2017-01-25 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Cryoelectron Microscopy Maps of Human Papillomavirus 16 Reveal L2 Densities and Heparin Binding Site. Structure, 25, 2017
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8FLK
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![BU of 8flk by Molmil](/molmil-images/mine/8flk) | Cryo-EM structure of STING oligomer bound to cGAMP and NVS-STG2 | Descriptor: | 4-({[4-(2-tert-butyl-5,5-dimethyl-1,3-dioxan-2-yl)phenyl]methyl}amino)-3-methoxybenzoic acid, Stimulator of interferon genes protein, cGAMP | Authors: | Li, J, Canham, S.M, Zhang, X, Bai, X, Feng, Y. | Deposit date: | 2022-12-21 | Release date: | 2023-11-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Activation of human STING by a molecular glue-like compound. Nat.Chem.Biol., 20, 2024
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8FLM
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![BU of 8flm by Molmil](/molmil-images/mine/8flm) | Cryo-EM structure of STING oligomer bound to cGAMP, NVS-STG2 and C53 | Descriptor: | 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide, 4-({[4-(2-tert-butyl-5,5-dimethyl-1,3-dioxan-2-yl)phenyl]methyl}amino)-3-methoxybenzoic acid, Stimulator of interferon genes protein, ... | Authors: | Li, J, Canham, S.M, Zhang, X, Bai, X, Feng, Y. | Deposit date: | 2022-12-21 | Release date: | 2023-11-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Activation of human STING by a molecular glue-like compound. Nat.Chem.Biol., 20, 2024
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6NAC
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![BU of 6nac by Molmil](/molmil-images/mine/6nac) | Crystal structure of [FeFe]-hydrogenase I (CpI) solved with single pulse free electron laser data | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, IRON/SULFUR CLUSTER, ... | Authors: | Cohen, A.E, Davidson, C.M, Zadvornyy, O.A, Keable, S.M, Lyubimov, A.Y, Song, J, McPhillips, S.E, Soltis, S.M, Peters, J.W. | Deposit date: | 2018-12-05 | Release date: | 2019-12-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Tuning Catalytic Bias of Hydrogen Gas Producing Hydrogenases. J.Am.Chem.Soc., 142, 2020
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1KZU
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![BU of 1kzu by Molmil](/molmil-images/mine/1kzu) | INTEGRAL MEMBRANE PERIPHERAL LIGHT HARVESTING COMPLEX FROM RHODOPSEUDOMONAS ACIDOPHILA STRAIN 10050 | Descriptor: | BACTERIOCHLOROPHYLL A, LIGHT HARVESTING PROTEIN B-800/850, Rhodopin b-D-glucoside | Authors: | Cogdell, R.J, Freer, A.A, Isaacs, N.W, Hawthornthwaite-Lawless, A.M, Mcdermott, G, Papiz, M.Z, Prince, S.M. | Deposit date: | 1996-08-31 | Release date: | 1997-04-01 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Apoprotein structure in the LH2 complex from Rhodopseudomonas acidophila strain 10050: modular assembly and protein pigment interactions. J.Mol.Biol., 268, 1997
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6N6P
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![BU of 6n6p by Molmil](/molmil-images/mine/6n6p) | Crystal structure of [FeFe]-hydrogenase in the presence of 7 mM Sodium dithionite | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, IRON/SULFUR CLUSTER, ... | Authors: | Zadvornyy, O.A, Keable, S.M, Peters, J.W. | Deposit date: | 2018-11-26 | Release date: | 2019-12-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Tuning Catalytic Bias of Hydrogen Gas Producing Hydrogenases. J.Am.Chem.Soc., 142, 2020
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3EDN
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![BU of 3edn by Molmil](/molmil-images/mine/3edn) | Crystal structure of the Bacillus anthracis phenazine biosynthesis protein, PhzF family | Descriptor: | MAGNESIUM ION, Phenazine biosynthesis protein, PhzF family, ... | Authors: | Anderson, S.M, Brunzelle, J.S, Onopriyenko, O, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2008-09-03 | Release date: | 2008-10-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of the Bacillus anthracis phenazine biosynthesis protein, PhzF family To be Published
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6N59
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![BU of 6n59 by Molmil](/molmil-images/mine/6n59) | 1.0 Angstrom crystal structure of [FeFe]-hydrogenase | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, IRON/SULFUR CLUSTER, ... | Authors: | Zadvornyy, O.A, Keable, S.M, Artz, J.H, Peters, J.W. | Deposit date: | 2018-11-21 | Release date: | 2019-12-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.02 Å) | Cite: | Tuning Catalytic Bias of Hydrogen Gas Producing Hydrogenases. J.Am.Chem.Soc., 142, 2020
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6I84
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![BU of 6i84 by Molmil](/molmil-images/mine/6i84) | Structure of transcribing RNA polymerase II-nucleosome complex | Descriptor: | DNA (158-MER), DNA (170-MER), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Farnung, L, Vos, S.M, Cramer, P. | Deposit date: | 2018-11-19 | Release date: | 2019-01-02 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structure of transcribing RNA polymerase II-nucleosome complex. Nat Commun, 9, 2018
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3EH5
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![BU of 3eh5 by Molmil](/molmil-images/mine/3eh5) | Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus | Descriptor: | COPPER (I) ION, Cytochrome c oxidase polypeptide 2A, Cytochrome c oxidase subunit 1, ... | Authors: | Liu, B, Chen, Y, Doukov, T, Soltis, S.M, Stout, D, Fee, J.A. | Deposit date: | 2008-09-11 | Release date: | 2009-04-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Combined microspectrophotometric and crystallographic examination of chemically reduced and X-ray radiation-reduced forms of cytochrome ba3 oxidase from Thermus thermophilus: structure of the reduced form of the enzyme. Biochemistry, 48, 2009
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6IDL
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![BU of 6idl by Molmil](/molmil-images/mine/6idl) | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 5.0 (Class II particle) | Descriptor: | Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... | Authors: | Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. | Deposit date: | 2018-09-10 | Release date: | 2018-12-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (25 Å) | Cite: | Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody. Structure, 27, 2019
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6ID6
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![BU of 6id6 by Molmil](/molmil-images/mine/6id6) | |
3EQE
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![BU of 3eqe by Molmil](/molmil-images/mine/3eqe) | Crystal structure of the YubC protein from Bacillus subtilis. Northeast Structural Genomics Consortium target SR112. | Descriptor: | FE (III) ION, Putative cystein dioxygenase | Authors: | Vorobiev, S.M, Su, M, Seetharaman, J, Benach, J, Forouhar, F, Clayton, G, Cooper, B, Wang, H, Foote, E.L, Ciccosanti, C, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-09-30 | Release date: | 2008-10-14 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Crystal structure of the YubC protein from Bacillus subtilis. To be Published
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2CE8
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![BU of 2ce8 by Molmil](/molmil-images/mine/2ce8) | |
6OM6
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![BU of 6om6 by Molmil](/molmil-images/mine/6om6) | Structure of trans-translation inhibitor bound to E. coli 70S ribosome with P site tRNA | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Hoffer, E.D, Mehrani, A, Keiler, K.C, Stagg, S.M, Dunham, C.M. | Deposit date: | 2019-04-18 | Release date: | 2021-02-10 | Last modified: | 2021-09-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo. Nat Commun, 12, 2021
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3MNZ
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![BU of 3mnz by Molmil](/molmil-images/mine/3mnz) | Crystal structure of the non-neutralizing HIV antibody 13H11 Fab fragment with a gp41 MPER-derived peptide bearing Ala substitutions in a helical conformation | Descriptor: | ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN, SODIUM ION, ... | Authors: | Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F. | Deposit date: | 2010-04-22 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of a Non-Neutralizing HIV-1 gp41 Envelope Antibody Demonstrates Neutralization Mechanism of gp41 Antibodies To be Published
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3MOD
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![BU of 3mod by Molmil](/molmil-images/mine/3mod) | Crystal structure of the neutralizing HIV antibody 2F5 Fab fragment (recombinantly produced IgG) with 11 aa gp41 MPER-derived peptide | Descriptor: | ANTI-HIV-1 ANTIBODY 2F5 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 2F5 LIGHT CHAIN, gp41 MPER-derived peptide | Authors: | Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F. | Deposit date: | 2010-04-22 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of a Non-Neutralizing HIV-1 gp41 Envelope Antibody Demonstrates Neutralization Mechanism of gp41 Antibodies To be Published
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3MNV
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![BU of 3mnv by Molmil](/molmil-images/mine/3mnv) | Crystal structure of the non-neutralizing HIV antibody 13H11 Fab fragment | Descriptor: | 1,2-ETHANEDIOL, ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN, ... | Authors: | Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F. | Deposit date: | 2010-04-22 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region. Nat.Struct.Mol.Biol., 17, 2010
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3MNW
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![BU of 3mnw by Molmil](/molmil-images/mine/3mnw) | Crystal structure of the non-neutralizing HIV antibody 13H11 Fab fragment with a gp41 MPER-derived peptide in a helical conformation | Descriptor: | 1,2-ETHANEDIOL, ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN, ... | Authors: | Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F. | Deposit date: | 2010-04-22 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of a Non-Neutralizing HIV-1 gp41 Envelope Antibody Demonstrates Neutralization Mechanism of gp41 Antibodies To be Published
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3MOB
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![BU of 3mob by Molmil](/molmil-images/mine/3mob) | Crystal structure of the neutralizing HIV antibody 2F5 Fab fragment (recombinantly produced Fab) with 11 aa gp41 MPER-derived peptide | Descriptor: | ANTI-HIV-1 ANTIBODY 2F5 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 2F5 LIGHT CHAIN, gp41 MPER-derived peptide | Authors: | Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F. | Deposit date: | 2010-04-22 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of a Non-Neutralizing HIV-1 gp41 Envelope Antibody Demonstrates Neutralization Mechanism of gp41 Antibodies To be Published
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