4CMM
 
 | | Structure of human CD47 in complex with human Signal Regulatory Protein (SIRP) alpha v1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUKOCYTE SURFACE ANTIGEN CD47, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 | | 著者 | Hatherley, D, Lea, S.M, Johnson, S, Barclay, A.N. | | 登録日 | 2014-01-16 | | 公開日 | 2014-02-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Polymorphisms in the Human Inhibitory Signal-Regulatory Protein Alpha Do not Affect Binding to its Ligand Cd47.
J.Biol.Chem., 289, 2014
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1YVW
 | | Crystal structure of Phosphoribosyl-ATP pyrophosphohydrolase from Bacillus cereus. NESGC target BcR13. | | 分子名称: | Phosphoribosyl-ATP pyrophosphatase | | 著者 | Benach, J, Kuzin, A.P, Forouhar, F, Abashidze, M, Vorobiev, S.M, Shastry, R, Rong, X, Acton, T.B, Montelione, G.T, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2005-02-16 | | 公開日 | 2005-03-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of Phosphoribosyl-ATP pyrophosphohydrolase from Bacillus cereus at 2.6 A resolution.
To be Published
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1YXB
 | | Crystal structure of Phosphoribosyl-ATP pyrophosphatase from Streptomyces coelicolor. NESG target RR8. | | 分子名称: | Phosphoribosyl-ATP pyrophosphatase | | 著者 | Benach, J, Kuzin, A.P, Forouhar, F, Abashidze, M, Vorobiev, S.M, Rong, X, Acton, T.B, Montelione, G.T, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2005-02-20 | | 公開日 | 2005-03-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of Phosphoribosyl-ATP pyrophosphatase from Streptomyces coelicolor. NESG target RR8.
To be Published
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3P2Q
 | | Crystal structure of the fluoroacetyl-CoA-specific thioesterase, FlK | | 分子名称: | Fluoroacetyl coenzyme A thioesterase | | 著者 | Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y. | | 登録日 | 2010-10-03 | | 公開日 | 2010-10-20 | | 最終更新日 | 2011-11-16 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
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4CGQ
 | | Full length Tah1 bound to HSP90 peptide SRMEEVD | | 分子名称: | CHLORIDE ION, HEAT SHOCK PROTEIN HSP 90-ALPHA, TPR REPEAT-CONTAINING PROTEIN ASSOCIATED WITH HSP90 | | 著者 | Roe, S.M, Pal, M. | | 登録日 | 2013-11-26 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Tah1 Helix-Swap Dimerization Prevents Mixed Hsp90 Co-Chaperone Complexes
Acta Crystallogr.,Sect.F, 71, 2015
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4CGP
 | | Leishmania major N-myristoyltransferase in complex with cofactor | | 分子名称: | GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, MAGNESIUM ION, TETRADECANOYL-COA | | 著者 | Brannigan, J.A, Roberts, S.M, Bell, A.S, Hutton, J.A, Smith, D.F, Tate, E.W, Leatherbarrow, R.J, Wilkinson, A.J. | | 登録日 | 2013-11-25 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Diverse Modes of Binding in Structures of Leishmania Major N-Myristoyltransferase with Selective Inhibitors
Iucrj, 1, 2014
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4CKT
 | | PIH1 N-terminal domain | | 分子名称: | PIH1 DOMAIN-CONTAINING PROTEIN 1, TELOMERE LENGTH REGULATION PROTEIN TEL2 HOMOLOG | | 著者 | Morgan, R.M, Roe, S.M. | | 登録日 | 2014-01-08 | | 公開日 | 2014-05-14 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1.
Structure, 22, 2014
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4CMV
 | | Crystal structure of Rv3378c | | 分子名称: | CITRIC ACID, DITERPENE SYNTHASE, MERCURY (II) ION | | 著者 | Layre, E, Lee, H.J, Young, D.C, Martinot, A.J, Buter, J, Minnaard, A.J, Annand, J.W, Fortune, S.M, Snider, B.B, Matsunaga, I, Rubin, E.J, Alber, T, Moody, D.B. | | 登録日 | 2014-01-18 | | 公開日 | 2014-02-19 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.307 Å) | | 主引用文献 | Molecular Profiling of Mycobacterium Tuberculosis Identifies Tuberculosinyl Nucleoside Products of the Virulence-Associated Enzyme Rv3378C.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3P3F
 | | Crystal structure of the F36A mutant of the fluoroacetyl-CoA-specific thioesterase FlK | | 分子名称: | Fluoroacetyl coenzyme A thioesterase | | 著者 | Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y. | | 登録日 | 2010-10-04 | | 公開日 | 2010-10-20 | | 最終更新日 | 2011-11-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
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3OJC
 | | Crystal structure of a putative Asp/Glu Racemase from Yersinia pestis | | 分子名称: | CALCIUM ION, HEXANE-1,6-DIOL, Putative aspartate/glutamate racemase | | 著者 | Anderson, S.M, Wawrzak, Z, Kudritska, M, Kwon, K, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2010-08-21 | | 公開日 | 2010-09-15 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of a putative Asp/Glu Racemase from Yersinia pestis
To be Published
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3R7O
 | | Structure of dually phosphorylated c-MET receptor kinase in complex with an MK-2461 analog | | 分子名称: | Hepatocyte growth factor receptor, N-[(2R)-1,4-dioxan-2-ylmethyl]-N-methyl-N'-{5-oxo-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl}sulfuric diamide | | 著者 | Soisson, S.M, Rickert, K, Patel, S.B, Munshi, S, Lumb, K.J. | | 登録日 | 2011-03-22 | | 公開日 | 2012-02-01 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for selective small molecule kinase inhibition of activated c-Met.
J.Biol.Chem., 286, 2011
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2AJ2
 | | X-Ray Crystal Structure of Protein VC0467 from Vibrio cholerae. Northeast Structural Genomics Consortium Target VcR8. | | 分子名称: | Hypothetical UPF0301 protein VC0467 | | 著者 | Kuzin, A.P, Abashidze, M, Vorobiev, S.M, Acton, T, Xiao, R, Conover, K, Ma, L.-C, Kellie, R, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2005-08-01 | | 公開日 | 2005-09-20 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | | 主引用文献 | X-Ray structure of hypothetical protein VC0467 from Vibrio cholerae: new fold. Northeast Structural Genomics Consortium target VcR8.
To be Published
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3RFB
 | | Structure of fRMsr | | 分子名称: | METHIONINE SULFOXIDE, Putative uncharacterized protein | | 著者 | Bong, S.M, Chi, Y.M. | | 登録日 | 2011-04-06 | | 公開日 | 2012-04-11 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of fRMsr
to be published
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3RFR
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4D0E
 | | Human Notch1 EGF domains 11-13 mutant GlcNAc-fucose disaccharide modified at T466 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | | 著者 | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | | 登録日 | 2014-04-25 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3Q4G
 | | Structure of NAD synthetase from Vibrio cholerae | | 分子名称: | CALCIUM ION, NH(3)-dependent NAD(+) synthetase | | 著者 | Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Peterson, S.N, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2010-12-23 | | 公開日 | 2011-01-26 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of NAD synthetase from Vibrio cholerae
TO BE PUBLISHED
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4CYN
 | | Leishmania major N-myristoyltransferase in complex with an aminoacylpyrrolidine inhibitor (2b) | | 分子名称: | (3R)-3-amino-4-(4-chlorophenyl)-1-[(3R,4S)-3-(4-chlorophenyl)-4-(hydroxymethyl)pyrrolidin-1-yl]butan-1-one, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, MAGNESIUM ION, ... | | 著者 | Hutton, J.A, Goncalves, V, Brannigan, J.A, Paape, D, Waugh, T, Roberts, S.M, Bell, A.S, Wilkinson, A.J, Smith, D.F, Leatherbarrow, R.J, Tate, E.W. | | 登録日 | 2014-04-14 | | 公開日 | 2014-10-01 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure-Based Design of Potent and Selective Leishmania N- Myristoyltransferase Inhibitors.
J.Med.Chem., 57, 2014
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3POM
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3ZKO
 | | The structure of ''breathing'' dengue virus. | | 分子名称: | ENVELOPE GLYCOPROTEIN | | 著者 | Fibriansah, G, Ng, T.S, Kostyuchenko, V.A, Lee, S, Wang, J, Lok, S.M. | | 登録日 | 2013-01-24 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (13.7 Å) | | 主引用文献 | Structural Changes of Dengue Virus When Exposed to 37 Degrees C.
J.Virol., 87, 2013
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3ZD1
 | | STRUCTURE OF THE TWO C-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 2 | | 分子名称: | 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 2 | | 著者 | Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M. | | 登録日 | 2012-11-23 | | 公開日 | 2013-03-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3PYP
 | | PHOTOACTIVE YELLOW PROTEIN, CRYOTRAPPED EARLY LIGHT CYCLE INTERMEDIATE | | 分子名称: | 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN | | 著者 | Genick, U.K, Soltis, S.M, Kuhn, P, Canestrelli, I.L, Getzoff, E.D. | | 登録日 | 1998-07-28 | | 公開日 | 1999-06-01 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | | 主引用文献 | Structure at 0.85 A resolution of an early protein photocycle intermediate.
Nature, 392, 1998
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2CTN
 | | STRUCTURE OF CALCIUM-SATURATED CARDIAC TROPONIN C, NMR, 30 STRUCTURES | | 分子名称: | CALCIUM ION, TROPONIN C | | 著者 | Sia, S.K, Li, M.X, Spyracopoulos, L, Gagne, S.M, Liu, W, Putkey, J.A, Sykes, B.D. | | 登録日 | 1997-05-06 | | 公開日 | 1998-05-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain.
J.Biol.Chem., 272, 1997
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3ZQ9
 | | Structure of a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 | | 分子名称: | (2R,3S,4R,5R)-5-(HYDROXYMETHYL)PIPERIDINE-2,3,4-TRIOL, 1,2-ETHANEDIOL, CALCIUM ION, ... | | 著者 | Ariza, A, Eklof, J.M, Spadiut, O, Offen, W.A, Roberts, S.M, Besenmatter, W, Friis, E.P, Skjot, M, Wilson, K.S, Brumer, H, Davies, G. | | 登録日 | 2011-06-08 | | 公開日 | 2011-06-22 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structure and Activity of Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44.
J.Biol.Chem., 286, 2011
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4CY4
 | | The Cryo-Electron Microscopy Structure of the CorA channel from Methanocaldococcus jannaschii at 21.6 Angstrom in low magnesium. | | 分子名称: | MAGNESIUM TRANSPORT PROTEIN CORA | | 著者 | Cleverley, R.M, Kean, J, Shintre, C.A, Baldock, C, Derrick, J.P, Ford, R.C, Prince, S.M. | | 登録日 | 2014-04-10 | | 公開日 | 2015-04-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (21.6 Å) | | 主引用文献 | The Cryo-EM structure of the CorA channel from Methanocaldococcus jannaschii in low magnesium conditions.
Biochim. Biophys. Acta, 1848, 2015
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4CYO
 | | Leishmania major N-myristoyltransferase in complex with a hybrid inhibitor (compound 21). | | 分子名称: | GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, MAGNESIUM ION, N-{5-[(3S,4R)-1-[(3R)-3-amino-4-(4-chlorophenyl)butanoyl]-4-(hydroxymethyl)pyrrolidin-3-yl]-2-chlorophenyl}-2-(4-fluorophenyl)acetamide, ... | | 著者 | Hutton, J.A, Goncalves, V, Brannigan, J.A, Paape, D, Waugh, T, Roberts, S.M, Bell, A.S, Wilkinson, A.J, Smith, D.F, Leatherbarrow, R.J, Tate, E.W. | | 登録日 | 2014-04-14 | | 公開日 | 2014-10-01 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure-Based Design of Potent and Selective Leishmania N- Myristoyltransferase Inhibitors.
J.Med.Chem., 57, 2014
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