1ZXM
| Human Topo IIa ATPase/AMP-PNP | Descriptor: | DNA topoisomerase II, alpha isozyme, MAGNESIUM ION, ... | Authors: | Wei, H, Ruthenburg, A.J, Bechis, S.K, Verdine, G.L. | Deposit date: | 2005-06-08 | Release date: | 2005-08-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Nucleotide-dependent Domain Movement in the ATPase Domain of a Human Type IIA DNA Topoisomerase. J.Biol.Chem., 280, 2005
|
|
1ZY5
| Crystal Structure of eIF2alpha Protein Kinase GCN2: R794G Hyperactivating Mutant Complexed with AMPPNP. | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase GCN2 | Authors: | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | Deposit date: | 2005-06-09 | Release date: | 2005-06-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2 J.Biol.Chem., 280, 2005
|
|
3QDK
| |
1ZXE
| Crystal Structure of eIF2alpha Protein Kinase GCN2: D835N Inactivating Mutant in Apo Form | Descriptor: | GLYCEROL, Serine/threonine-protein kinase | Authors: | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | Deposit date: | 2005-06-07 | Release date: | 2005-06-21 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2 J.Biol.Chem., 280, 2005
|
|
3QRA
| The crystal structure of Ail, the attachment invasion locus protein of Yersinia pestis | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Attachment invasion locus protein | Authors: | Yamashita, S, Lukacik, P, Noinaj, N, Buchanan, S.K. | Deposit date: | 2011-02-17 | Release date: | 2011-11-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Structural Insights into Ail-Mediated Adhesion in Yersinia pestis. Structure, 19, 2011
|
|
2ADU
| Human Methionine Aminopeptidase Complex with 4-Aryl-1,2,3-triazole Inhibitor | Descriptor: | 4-(3-METHYLPHENYL)-1H-1,2,3-TRIAZOLE, COBALT (II) ION, Methionine aminopeptidase 2 | Authors: | Kallander, L.S, Lu, Q, Chen, W, Tomaszek, T, Yang, G, Tew, D, Meek, T.D, Hofmann, G.A, Schulz-Pritchard, C.K, Smith, W.W, Janson, C.A, Ryan, M.D, Zhang, G.F, Johanson, K.O, Kirkpatrick, R.B, Ho, T.F, Fisher, P.W, Mattern, M.R, Johnson, R.K, Hansbury, M.J, Winkler, J.D, Ward, K.W, Veber, D.F, Thompson, S.K. | Deposit date: | 2005-07-20 | Release date: | 2005-09-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | 4-Aryl-1,2,3-triazole: A Novel Template for a Reversible Methionine Aminopeptidase 2 Inhibitor, Optimized To Inhibit Angiogenesis in Vivo J.Med.Chem., 48, 2005
|
|
2A65
| Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters | Descriptor: | CHLORIDE ION, LEUCINE, Na(+):neurotransmitter symporter (Snf family), ... | Authors: | Yamashita, A, Singh, S.K, Kawate, T, Jin, Y, Gouaux, E. | Deposit date: | 2005-07-01 | Release date: | 2005-08-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of a bacterial homologue of Na(+)/Cl(-)-dependent neurotransmitter transporters. Nature, 437, 2005
|
|
3QQX
| Reduced Native Intermediate of the Multicopper Oxidase CueO | Descriptor: | Blue copper oxidase CueO, COPPER (I) ION, COPPER (II) ION, ... | Authors: | Montfort, W.R, Roberts, S.A, Singh, S.K. | Deposit date: | 2011-02-16 | Release date: | 2012-02-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | CueO E506D Mutant: Crystal Structure of Reduced Native Intermediate, Kinetics, and Impairment of Product Release To be Published
|
|
3QRC
| The crystal structure of Ail, the attachment invasion locus protein of Yersinia pestis, in complex with the heparin analogue sucrose octasulfate | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, Attachment invasion locus protein | Authors: | Yamashita, S, Lukacik, P, Noinaj, N, Buchanan, S.K. | Deposit date: | 2011-02-17 | Release date: | 2011-11-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.852 Å) | Cite: | Structural Insights into Ail-Mediated Adhesion in Yersinia pestis. Structure, 19, 2011
|
|
2GU1
| Crystal structure of a zinc containing peptidase from vibrio cholerae | Descriptor: | SODIUM ION, ZINC ION, Zinc peptidase | Authors: | Sugadev, R, Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2006-04-28 | Release date: | 2006-07-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of a putative lysostaphin peptidase from Vibrio cholerae. Proteins, 72, 2008
|
|
2GVC
| Crystal structure of flavin-containing monooxygenase (FMO)from S.pombe and substrate (methimazole) complex | Descriptor: | 1-METHYL-1,3-DIHYDRO-2H-IMIDAZOLE-2-THIONE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Eswaramoorthy, S, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2006-05-02 | Release date: | 2006-06-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Mechanism of action of a flavin-containing monooxygenase. Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
4B7B
| Eg5-3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CADMIUM ION, CALCIUM ION, ... | Authors: | Talapatra, S.K, Kozielski, F. | Deposit date: | 2012-08-17 | Release date: | 2013-07-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Mitotic Kinesin Eg5 Overcomes Inhibition to the Phase I/II Clinical Candidate Sb743921 by an Allosteric Resistance Mechanism. J.Med.Chem., 56, 2013
|
|
3T8L
| Crystal Structure of adenine deaminase with Mn/Fe | Descriptor: | Adenine deaminase 2, UNKNOWN ATOM OR ION | Authors: | Bagaria, A, Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2011-08-01 | Release date: | 2011-11-02 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The catalase activity of diiron adenine deaminase. Protein Sci., 20, 2011
|
|
3TA4
| Small laccase from Amycolatopsis sp. ATCC 39116 complexed with 1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)-1,3-dihydroxypropane | Descriptor: | (1R,2S)-1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol, COPPER (II) ION, small laccase, ... | Authors: | Lukk, T, Majumdar, S, Gerlt, J.A, Nair, S.K. | Deposit date: | 2011-08-03 | Release date: | 2012-09-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Roles of small laccases from Streptomyces in lignin degradation. Biochemistry, 53, 2014
|
|
3TBB
| Small laccase from Streptomyces viridosporus T7A; alternate crystal form. | Descriptor: | COPPER (II) ION, OXYGEN MOLECULE, PHOSPHATE ION, ... | Authors: | Lukk, T, Majumdar, S, Gerlt, J.A, Nair, S.K. | Deposit date: | 2011-08-05 | Release date: | 2012-08-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Roles of small laccases from Streptomyces in lignin degradation. Biochemistry, 53, 2014
|
|
3TLE
| |
1Z2L
| Crystal structure of Allantoate-amidohydrolase from E.coli K12 in complex with substrate Allantoate | Descriptor: | ALLANTOATE ION, Allantoate amidohydrolase, SULFATE ION, ... | Authors: | Agarwal, R, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2005-03-08 | Release date: | 2005-03-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural analysis of a ternary complex of allantoate amidohydrolase from Escherichia coli reveals its mechanics. J.Mol.Biol., 368, 2007
|
|
3TVI
| Crystal structure of Clostridium acetobutylicum aspartate kinase (CaAK): An important allosteric enzyme for industrial amino acids production | Descriptor: | ASPARTIC ACID, Aspartokinase, LYSINE | Authors: | Manjasetty, B.A, Chance, M.R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2011-09-20 | Release date: | 2011-11-09 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of Clostridium acetobutylicum Aspartate kinase (CaAK): An important allosteric enzyme for amino acids production. Biotechnol Rep (Amst), 3, 2014
|
|
4B3S
| Crystal structure of the 30S ribosome in complex with compound 37 | Descriptor: | (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-4-O-benzyl-2-deoxy-alpha-D-glucopyranoside, 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Ng, C.L, Lang, K, Shcherbakov, D, Matt, T, Perez-Fernandez, D, Patak, R, Meyer, M, Duscha, S, Akbergenov, R, Boukari, H, Freihofer, P, Kudyba, I, Reddy, M.S.K, Nandurikar, R.S, Ramakrishnan, V, Vasella, A, Bottger, E.C. | Deposit date: | 2012-07-26 | Release date: | 2013-08-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | 4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics Nat.Commun., 5, 2014
|
|
2KKI
| |
1ZXN
| Human DNA topoisomerase IIa ATPase/ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA topoisomerase II, alpha isozyme, ... | Authors: | Wei, H, Ruthenburg, A.J, Bechis, S.K, Verdine, G.L. | Deposit date: | 2005-06-08 | Release date: | 2005-08-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Nucleotide-dependent Domain Movement in the ATPase Domain of a Human Type IIA DNA Topoisomerase. J.Biol.Chem., 280, 2005
|
|
1ZYD
| Crystal Structure of eIF2alpha Protein Kinase GCN2: Wild-Type Complexed with ATP. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase GCN2 | Authors: | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | Deposit date: | 2005-06-09 | Release date: | 2005-06-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2 J.Biol.Chem., 280, 2005
|
|
3TLB
| |
1SZG
| A198G:L230A flavocytochrome b2 with sulfite bound | Descriptor: | Cytochrome b2, mitochondrial, N-SULFO-FLAVIN MONONUCLEOTIDE | Authors: | Mowat, C.G, Wehenkel, A, Green, A.J, Walkinshaw, M.D, Reid, G.A, Chapman, S.K. | Deposit date: | 2004-04-05 | Release date: | 2004-07-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Altered Substrate Specificity in Flavocytochrome b(2): Structural Insights into the Mechanism of l-Lactate Dehydrogenation Biochemistry, 43, 2004
|
|
3QLD
| |