1ZY5
Crystal Structure of eIF2alpha Protein Kinase GCN2: R794G Hyperactivating Mutant Complexed with AMPPNP.
Summary for 1ZY5
| Entry DOI | 10.2210/pdb1zy5/pdb |
| Related | 1ZXE 1ZY4 1ZYC 1ZYD |
| Descriptor | Serine/threonine-protein kinase GCN2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total) |
| Functional Keywords | translation regulator, protein kinase, signal transduction, amino-acid starvation, starvation stress response, eif2alpha kinase, transferase |
| Biological source | Saccharomyces cerevisiae (baker's yeast) More |
| Total number of polymer chains | 2 |
| Total formula weight | 71147.67 |
| Authors | Padyana, A.K.,Qiu, H.,Roll-Mecak, A.,Hinnebusch, A.G.,Burley, S.K. (deposition date: 2005-06-09, release date: 2005-06-21, Last modification date: 2024-02-14) |
| Primary citation | Padyana, A.K.,Qiu, H.,Roll-Mecak, A.,Hinnebusch, A.G.,Burley, S.K. Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2 J.Biol.Chem., 280:29289-29299, 2005 Cited by PubMed: 15964839DOI: 10.1074/jbc.M504096200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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